{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,22]],"date-time":"2024-06-22T00:21:32Z","timestamp":1719015692624},"reference-count":25,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,6,20]]},"DOI":"10.7759\/cureus.62790","type":"journal-article","created":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T03:00:36Z","timestamp":1718938836000},"source":"Crossref","is-referenced-by-count":0,"title":["An Autopsy Case of Severe COVID-19 Pneumonia Complicated by Intrapulmonary Thrombosis in Myelodysplastic\/Myeloproliferative Neoplasm With Ring Sideroblasts and Thrombocytosis"],"prefix":"10.7759","author":[{"given":"Yoshinori","family":"Harada","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masahiro","family":"Makino","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryuta","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yuji","family":"Shimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takehiro","family":"Ogata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiyo","family":"Hayakawa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirokazu","family":"Shiraishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Junya","family":"Kuroda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Satoaki","family":"Matoba","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Tanaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.2266-23","article-title":"Internal medicine year in review 2022","volume":"62","author":"Ogasawara N","year":"2023","unstructured":"Ogasawara N, Matsunaga K, Isomoto H, Shimizu W. Internal medicine year in review 2022. Intern Med. 2023, 62:3431-5. 10.2169\/internalmedicine.2266-23","journal-title":"Intern Med"},{"key":"ref2","unstructured":"WHO. Coronavirus (COVID-19) dashboard. (2023). Accessed: June 30, 2023: https:\/\/covid19.who.int."},{"key":"ref3","unstructured":"WHO. Statement on the fifteenth meeting of the IHR (2005) Emergency Committee on the COVID-19 pandemic. (2023). Accessed: June 30, 2023: https:\/\/www.who.int\/news\/item\/05-05-2023-statement-on-the-fifteenth-meeting-of-the-international-health-regulations-(...."},{"key":"ref4","article-title":"Coronavirus disease 2019 morbid pulmonary pathology: what did we learn from autopsy examinations?","volume":"7","author":"Zulfu A","year":"2021","unstructured":"Zulfu A, Hamid ST, Elseed KA, Elmadhoun WM, Ahmed M, Ahmed MH. Coronavirus disease 2019 morbid pulmonary pathology: what did we learn from autopsy examinations?. J Clin Transl Res. 2021, 7:479-84.","journal-title":"J Clin Transl Res"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.25573","article-title":"Histopathological findings in COVID-19 cases: a systematic review","volume":"14","author":"Hammoud H","year":"2022","unstructured":"Hammoud H, Bendari A, Bendari T, Bougmiza I. Histopathological findings in COVID-19 cases: a systematic review. Cureus. 2022, 14:e25573. 10.7759\/cureus.25573","journal-title":"Cureus"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/d41586-020-01403-8","article-title":"Coronavirus blood-clot mystery intensifies","volume":"581","author":"Willyard C","year":"2020","unstructured":"Willyard C. Coronavirus blood-clot mystery intensifies. Nature. 2020, 581:250. 10.1038\/d41586-020-01403-8","journal-title":"Nature"},{"key":"ref7","article-title":"","author":"Swerdlow SH","year":"2017","unstructured":"Swerdlow SH, Campo E, Harris NL, Jaffe ES, Pileri SA, Stein H, Thiele J. WHO Classification of Tumours of Haematopoietic and Lymphoid Tissues. IARC, Lyon, France; 2017. https:\/\/publications.iarc.fr\/Book-And-Report-Series\/Who-Classification-Of-Tumours\/WHO-Classification-Of-Tumours-Of-Ha...."},{"key":"ref8","unstructured":"NIH. Final NIH coronavirus disease (COVID-19) treatment guidelines (February 29, 2024). (2024). Accessed: May 30, 2024: https:\/\/www.covid19treatmentguidelines.nih.gov\/."},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2011.053918","article-title":"Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis","volume":"97","author":"Broseus J","year":"2012","unstructured":"Broseus J, Florensa L, Zipperer E, et al.. Clinical features and course of refractory anemia with ring sideroblasts associated with marked thrombocytosis. Haematologica. 2012, 97:1036-41. 10.3324\/haematol.2011.053918","journal-title":"Haematologica"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-05-025544","article-title":"Management of extreme thrombocytosis in otherwise low-risk essential thrombocythemia; does number matter?","volume":"108","author":"Tefferi A","year":"2006","unstructured":"Tefferi A, Gangat N, Wolanskyj AP. Management of extreme thrombocytosis in otherwise low-risk essential thrombocythemia; does number matter?. Blood. 2006, 108:2493-4. 10.1182\/blood-2006-05-025544","journal-title":"Blood"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-02-339002","article-title":"Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: an international study of 891 patients","volume":"117","author":"Carobbio A","year":"2011","unstructured":"Carobbio A, Thiele J, Passamonti F, et al.. Risk factors for arterial and venous thrombosis in WHO-defined essential thrombocythemia: an international study of 891 patients. Blood. 2011, 117:5857-9. 10.1182\/blood-2011-02-339002","journal-title":"Blood"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-04-424911","article-title":"Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort","volume":"120","author":"Campbell PJ","year":"2012","unstructured":"Campbell PJ, MacLean C, Beer PA, et al.. Correlation of blood counts with vascular complications in essential thrombocythemia: analysis of the prospective PT1 cohort. Blood. 2012, 120:1409-11. 10.1182\/blood-2012-04-424911","journal-title":"Blood"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2021-246700","article-title":"COVID-19 with essential thrombocythemia treated with apixaban for antithrombotic prophylaxis","volume":"14","author":"Takasaki K","year":"2021","unstructured":"Takasaki K, Tsunenari T, Mori K, Aochi S. COVID-19 with essential thrombocythemia treated with apixaban for antithrombotic prophylaxis. BMJ Case Rep. 2021, 14:e246700. 10.1136\/bcr-2021-246700","journal-title":"BMJ Case Rep"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2022009022","article-title":"Circulating SARS-CoV-2+ megakaryocytes are associated with severe viral infection in COVID-19","volume":"7","author":"Fortmann SD","year":"2023","unstructured":"Fortmann SD, Patton MJ, Frey BF, et al.. Circulating SARS-CoV-2+ megakaryocytes are associated with severe viral infection in COVID-19. Blood Adv. 2023, 7:4200-14. 10.1182\/bloodadvances.2022009022","journal-title":"Blood Adv"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-020-02926-1","article-title":"Increased number of pulmonary megakaryocytes in COVID-19 patients with diffuse alveolar damage: an autopsy study with clinical correlation and review of the literature","volume":"478","author":"Valdivia-Mazeyra MF","year":"2021","unstructured":"Valdivia-Mazeyra MF, Salas C, Nieves-Alonso JM, et al.. Increased number of pulmonary megakaryocytes in COVID-19 patients with diffuse alveolar damage: an autopsy study with clinical correlation and review of the literature. Virchows Arch. 2021, 478:487-96. 10.1007\/s00428-020-02926-1","journal-title":"Virchows Arch"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(20)30434-5","article-title":"Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study","volume":"20","author":"Carsana L","year":"2020","unstructured":"Carsana L, Sonzogni A, Nasr A, et al.. Pulmonary post-mortem findings in a series of COVID-19 cases from northern Italy: a two-centre descriptive study. Lancet Infect Dis. 2020, 20:1135-40. 10.1016\/S1473-3099(20)30434-5","journal-title":"Lancet Infect Dis"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.807934","article-title":"The COVID complex: a review of platelet activation and immune complexes in COVID-19","volume":"13","author":"Jevtic SD","year":"2022","unstructured":"Jevtic SD, Nazy I. The COVID complex: a review of platelet activation and immune complexes in COVID-19. Front Immunol. 2022, 13:807934. 10.3389\/fimmu.2022.807934","journal-title":"Front Immunol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-022-04318-x","article-title":"Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19","volume":"79","author":"Zhu A","year":"2022","unstructured":"Zhu A, Real F, Capron C, et al.. Infection of lung megakaryocytes and platelets by SARS-CoV-2 anticipate fatal COVID-19. Cell Mol Life Sci. 2022, 79:365. 10.1007\/s00018-022-04318-x","journal-title":"Cell Mol Life Sci"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15534","article-title":"Platelets contribute to disease severity in COVID-19","volume":"19","author":"Barrett TJ","year":"2021","unstructured":"Barrett TJ, Bilaloglu S, Cornwell M, et al.. Platelets contribute to disease severity in COVID-19. J Thromb Haemost. 2021, 19:3139-53. 10.1111\/jth.15534","journal-title":"J Thromb Haemost"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2020007252","article-title":"Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19","volume":"136","author":"Hottz ED","year":"2020","unstructured":"Hottz ED, Azevedo-Quintanilha IG, Palhinha L, et al.. Platelet activation and platelet-monocyte aggregate formation trigger tissue factor expression in patients with severe COVID-19. Blood. 2020, 136:1330-41. 10.1182\/blood.2020007252","journal-title":"Blood"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2021011871","article-title":"Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets","volume":"138","author":"Bye AP","year":"2021","unstructured":"Bye AP, Hoepel W, Mitchell JL, et al.. Aberrant glycosylation of anti-SARS-CoV-2 spike IgG is a prothrombotic stimulus for platelets. Blood. 2021, 138:1481-9. 10.1182\/blood.2021011871","journal-title":"Blood"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2024.02.011","article-title":"2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19","volume":"22","author":"Schulman S","year":"2024","unstructured":"Schulman S, Arnold DM, Bradbury CA, et al.. 2023 ISTH update of the 2022 ISTH guidelines for antithrombotic treatment in COVID-19. J Thromb Haemost. 2024, 22:1779-97. 10.1016\/j.jtha.2024.02.011","journal-title":"J Thromb Haemost"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n2400","article-title":"Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial","volume":"375","author":"Sholzberg M","year":"2021","unstructured":"Sholzberg M, Tang GH, Rahhal H, et al.. Effectiveness of therapeutic heparin versus prophylactic heparin on death, mechanical ventilation, or intensive care unit admission in moderately ill patients with covid-19 admitted to hospital: RAPID randomised clinical trial. BMJ. 2021, 375:n2400. 10.1136\/bmj.n2400","journal-title":"BMJ"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2105911","article-title":"Therapeutic anticoagulation with heparin in noncritically ill patients with covid-19","volume":"385","author":"Lawler PR","year":"2021","unstructured":"Lawler PR, Goligher EC, Berger JS, et al.. Therapeutic anticoagulation with heparin in noncritically ill patients with covid-19. N Engl J Med. 2021, 385:790-802. 10.1056\/NEJMoa2105911","journal-title":"N Engl J Med"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2103417","article-title":"Therapeutic anticoagulation with heparin in critically ill patients with covid-19","volume":"385","author":"Goligher EC","year":"2021","unstructured":"Goligher EC, Bradbury CA, McVerry BJ, et al.. Therapeutic anticoagulation with heparin in critically ill patients with covid-19. N Engl J Med. 2021, 385:777-89. 10.1056\/NEJMoa2103417","journal-title":"N Engl J Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/228722-an-autopsy-case-of-severe-covid-19-pneumonia-complicated-by-intrapulmonary-thrombosis-in-myelodysplasticmyeloproliferative-neoplasm-with-ring-sideroblasts-and-thrombocytosis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,21]],"date-time":"2024-06-21T03:00:45Z","timestamp":1718938845000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/228722-an-autopsy-case-of-severe-covid-19-pneumonia-complicated-by-intrapulmonary-thrombosis-in-myelodysplasticmyeloproliferative-neoplasm-with-ring-sideroblasts-and-thrombocytosis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,20]]},"references-count":25,"URL":"https:\/\/doi.org\/10.7759\/cureus.62790","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,6,20]]}}}