{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,2]],"date-time":"2025-06-02T14:51:31Z","timestamp":1748875891318},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,21]]},"DOI":"10.7759\/cureus.65049","type":"journal-article","created":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T18:30:31Z","timestamp":1721586631000},"source":"Crossref","is-referenced-by-count":1,"title":["A Comparative Study of the Cardiovascular Effects of a Lower Dose of Heat-Stable Carbetocin Versus the Standard Dose in the Prevention of Postpartum Hemorrhage During Elective Cesarean Delivery: A Single-Blinded, Randomized, Parallel-Group Trial"],"prefix":"10.7759","author":[{"given":"Rajasri G","family":"Yaliwal","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neelamma G","family":"Patil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shailaja","family":"Bidri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(14)70227-X","article-title":"Global causes of maternal death: a WHO systematic analysis","volume":"2","author":"Say L","year":"2014","unstructured":"Say L, Chou D, Gemmill A, et al.. Global causes of maternal death: a WHO systematic analysis. Lancet Glob Health. 2014, 2:323-33. 10.1016\/S2214-109X(14)70227-X","journal-title":"Lancet Glob Health"},{"key":"ref2","unstructured":"WHO recommendations. uterotonics for the prevention of postpartum haemorrhage. (2018). Accessed: March 2, 2024: https:\/\/iris.who.int\/bitstream\/handle\/10665\/277276\/9789241550420-eng.pdf."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aen071","article-title":"Signs of myocardial ischaemia after injection of oxytocin: a randomized double-blind comparison of oxytocin and methylergometrine during caesarean section","volume":"100","author":"Svanstr\u00f6m MC","year":"2008","unstructured":"Svanstr\u00f6m MC, Biber B, Hanes M, Johansson G, N\u00e4slund U, B\u00e5lfors EM. Signs of myocardial ischaemia after injection of oxytocin: a randomized double-blind comparison of oxytocin and methylergometrine during caesarean section. Br J Anaesth. 2008, 100:683-9. 10.1093\/bja\/aen071","journal-title":"Br J Anaesth"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.tjog.2018.06.001","article-title":"Postpartum hemorrhage: a value of carbetocin","volume":"57","author":"Wang PH","year":"2018","unstructured":"Wang PH. Postpartum hemorrhage: a value of carbetocin. Taiwan J Obstet Gynecol. 2018, 57:473-4. 10.1016\/j.tjog.2018.06.001","journal-title":"Taiwan J Obstet Gynecol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-013-0082-9","article-title":"Carbetocin at elective cesarean delivery: a sequential allocation trial to determine the minimum effective dose","volume":"61","author":"Khan M","year":"2014","unstructured":"Khan M, Balki M, Ahmed I, Farine D, Seaward G, Carvalho JC. Carbetocin at elective cesarean delivery: a sequential allocation trial to determine the minimum effective dose. Can J Anaesth. 2014, 61:242-8. 10.1007\/s12630-013-0082-9","journal-title":"Can J Anaesth"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpobgyn.2019.04.001","article-title":"Carbetocin: worth the extra expense?","volume":"61","author":"Gallos ID","year":"2019","unstructured":"Gallos ID, Coomarasamy A. Carbetocin: worth the extra expense?. Best Pract Res Clin Obstet Gynaecol. 2019, 61:55-65. 10.1016\/j.bpobgyn.2019.04.001","journal-title":"Best Pract Res Clin Obstet Gynaecol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1080\/14767058.2023.2208252","article-title":"Cardiovascular effects of oxytocin and carbetocin at cesarean section. A prospective double-blind randomized study using noninvasive pulse wave analysis","volume":"36","author":"Rabow S","year":"2023","unstructured":"Rabow S, Jonsson H, Bro E, Olofsson P. Cardiovascular effects of oxytocin and carbetocin at cesarean section. A prospective double-blind randomized study using noninvasive pulse wave analysis. J Matern Fetal Neonatal Med. 2023, 36:2208252. 10.1080\/14767058.2023.2208252","journal-title":"J Matern Fetal Neonatal Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpa.2022.02.002","article-title":"Optimal uterotonic management","volume":"36","author":"Heesen M","year":"2022","unstructured":"Heesen M, Orbach-Zinger S. Optimal uterotonic management. Best Pract Res Clin Anaesthesiol. 2022, 36:135-55. 10.1016\/j.bpa.2022.02.002","journal-title":"Best Pract Res Clin Anaesthesiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5812\/aapm-128782","article-title":"Hemodynamic effects of oxytocin and carbetocin during elective cesarean section in preeclamptic patients under spinal anesthesia: a randomized double-blind controlled study","volume":"13","author":"Bahr MH","year":"2023","unstructured":"Bahr MH, Abdelaal Ahmed Mahmoud M Alkhatip A, Ahmed AG, Elgamel AF, Abdelkader M, Hussein HA. Hemodynamic effects of oxytocin and carbetocin during elective cesarean section in preeclamptic patients under spinal anesthesia: a randomized double-blind controlled study. Anesth Pain Med. 2023, 13:e128782. 10.5812\/aapm-128782","journal-title":"Anesth Pain Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.preghy.2012.01.002","article-title":"The maternal cardiovascular effect of carbetocin compared to oxytocin in women undergoing caesarean section","volume":"2","author":"Pisani I","year":"2012","unstructured":"Pisani I, Tiralongo GM, Gagliardi G, Scala RL, Todde C, Frigo MG, Valensise H. The maternal cardiovascular effect of carbetocin compared to oxytocin in women undergoing caesarean section. Pregnancy Hypertens. 2012, 2:139-42. 10.1016\/j.preghy.2012.01.002","journal-title":"Pregnancy Hypertens"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0000000000004712","article-title":"The effect of carbetocin dose on transmural dispersion of myocardial repolarization in healthy parturients scheduled for elective cesarean delivery under spinal anesthesia: a prospective, randomized clinical trial","volume":"132","author":"Clunies-Ross N","year":"2021","unstructured":"Clunies-Ross N, Roston TM, Taylor J, Whyte S, Albert A, G\u00f6rges M, Chau A. The effect of carbetocin dose on transmural dispersion of myocardial repolarization in healthy parturients scheduled for elective cesarean delivery under spinal anesthesia: a prospective, randomized clinical trial. Anesth Analg. 2021, 132:485-92. 10.1213\/ANE.0000000000004712","journal-title":"Anesth Analg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/anae.14480","article-title":"Uterotonics in elective caesarean delivery: a randomised non-inferiority study comparing carbetocin 20 \u03bcg and 100 \u03bcg","volume":"74","author":"Tabl S","year":"2019","unstructured":"Tabl S, Balki M, Downey K, Tomlinson G, Farine D, Seaward G, Carvalho JC. Uterotonics in elective caesarean delivery: a randomised non-inferiority study comparing carbetocin 20 \u03bcg and 100 \u03bcg. Anaesthesia. 2019, 74:190-6. 10.1111\/anae.14480","journal-title":"Anaesthesia"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s12630-022-02227-y","article-title":"Comparison of carbetocin as a bolus or an infusion with prophylactic phenylephrine on maternal heart rate during cesarean delivery under spinal anesthesia: a double-blinded randomized controlled trial","volume":"69","author":"Boisselle M\u00c8","year":"2022","unstructured":"Boisselle M\u00c8, Zaphiratos VV, Fortier A, Richeb\u00e9 P, Loubert C. Comparison of carbetocin as a bolus or an infusion with prophylactic phenylephrine on maternal heart rate during cesarean delivery under spinal anesthesia: a double-blinded randomized controlled trial. Can J Anaesth. 2022, 69:715-25. 10.1007\/s12630-022-02227-y","journal-title":"Can J Anaesth"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD005457.pub4","article-title":"Carbetocin for preventing postpartum haemorrhage","author":"Su LL","year":"2012","unstructured":"Su LL, Chong YS, Samuel M. Carbetocin for preventing postpartum haemorrhage. Cochrane Database Syst Rev. 2012, CD005457. 10.1002\/14651858.CD005457.pub4","journal-title":"Cochrane Database Syst Rev"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1136\/dtb.2021.000030","article-title":"Is there a role for carbetocin in the prophylaxis of postpartum obstetric haemorrhage?","volume":"60","author":"Day A","year":"2022","unstructured":"Day A, Barclay P, Page L. Is there a role for carbetocin in the prophylaxis of postpartum obstetric haemorrhage?. Drug Ther Bull. 2022, 60:136-40. 10.1136\/dtb.2021.000030","journal-title":"Drug Ther Bull"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/259646-a-comparative-study-of-the-cardiovascular-effects-of-a-lower-dose-of-heat-stable-carbetocin-versus-the-standard-dose-in-the-prevention-of-postpartum-hemorrhage-during-elective-cesarean-delivery-a-single-blinded-randomized-parallel-group-trial","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,21]],"date-time":"2024-07-21T18:30:34Z","timestamp":1721586634000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/259646-a-comparative-study-of-the-cardiovascular-effects-of-a-lower-dose-of-heat-stable-carbetocin-versus-the-standard-dose-in-the-prevention-of-postpartum-hemorrhage-during-elective-cesarean-delivery-a-single-blinded-randomized-parallel-group-trial"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,21]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.65049","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7,21]]}}}