{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T07:00:10Z","timestamp":1788418810703,"version":"build-2803163510"},"reference-count":37,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,22]]},"DOI":"10.7759\/cureus.65075","type":"journal-article","created":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T08:52:15Z","timestamp":1721638335000},"source":"Crossref","is-referenced-by-count":1,"title":["Determining Split Renal Function in Children With Ureteropelvic Junction Stenosis: Technetium-99m Mercaptoacetyltriglycine (Tc-99m MAG-3) or Technetium-99m Dimercaptosuccinic Acid (Tc-99m DMSA)?"],"prefix":"10.7759","author":[{"given":"Hale","family":"\u00d6zdemir","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u0130lknur","family":"Giri\u015fgen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga","family":"Yaylal\u0131","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T\u00fclay","family":"Becerir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u00d6zkan","family":"Herek","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hande","family":"\u015eenol","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sel\u00e7uk","family":"Y\u00fcksel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2010.02.205","article-title":"The Society for Fetal Urology consensus statement on the evaluation and management of antenatal hydronephrosis","volume":"6","author":"Nguyen HT","year":"2010","unstructured":"Nguyen HT, Herndon CD, Cooper C, et al.. The Society for Fetal Urology consensus statement on the evaluation and management of antenatal hydronephrosis. J Pediatr Urol. 2010, 6:212-231. 10.1016\/j.jpurol.2010.02.205","journal-title":"J Pediatr Urol"},{"key":"ref2","article-title":"Quantitative SPECT of 99mTc-DMSA uptake in kidneys of infants with unilateral ureteropelvic junction obstruction: assessment of structural and functional abnormalities","volume":"40","author":"Groshar D","year":"1999","unstructured":"Groshar D, Wald M, Moskovitz B, Issaq E, Nativ OJ. Quantitative SPECT of 99mTc-DMSA uptake in kidneys of infants with unilateral ureteropelvic junction obstruction: assessment of structural and functional abnormalities. J Nucl Med. 1999, 40:11-15.","journal-title":"J Nucl Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2008.08.512","article-title":"Operative versus nonoperative management of ureteropelvic junction obstruction in children","volume":"73","author":"Heinlen JE","year":"2009","unstructured":"Heinlen JE, Manatt CS, Bright BC, Kropp BP, Campbell JB, Frimberger D. Operative versus nonoperative management of ureteropelvic junction obstruction in children. Urology. 2009, 73:521-525. 10.1016\/j.urology.2008.08.512","journal-title":"Urology"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s12149-010-0397-3","article-title":"Relative renal function with MAG-3 and DMSA in children with unilateral hydronephrosis","volume":"24","author":"Akta\u015f GE","year":"2010","unstructured":"Akta\u015f GE, Inanir S. Relative renal function with MAG-3 and DMSA in children with unilateral hydronephrosis. Ann Nucl Med. 2010, 24:691-695. 10.1007\/s12149-010-0397-3","journal-title":"Ann Nucl Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2009.09.006","article-title":"Round table on the management of renal pelvic dilatation in children","volume":"5","author":"Piepsz A","year":"2009","unstructured":"Piepsz A, Gordon I, Brock J 3rd, Koff S. Round table on the management of renal pelvic dilatation in children. J Pediatr Urol. 2009, 5:437-444. 10.1016\/j.jpurol.2009.09.006","journal-title":"J Pediatr Urol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s12098-017-2346-9","article-title":"Is it always necessary to treat an asymptomatic hydronephrosis due to ureteropelvic junction obstruction?","volume":"84","author":"Sarin YK","year":"2017","unstructured":"Sarin YK. Is it always necessary to treat an asymptomatic hydronephrosis due to ureteropelvic junction obstruction?. Indian J Pediatr. 2017, 84:531-539. 10.1007\/s12098-017-2346-9","journal-title":"Indian J Pediatr"},{"key":"ref7","article-title":"\u00dcreteropelvik Bile\u015fke Darl\u0131klar\u0131nda Tan\u0131 ve Takip","author":"\u015eahinkanat T","year":"2015","unstructured":"\u015eahinkanat T. \u00dcreteropelvik Bile\u015fke Darl\u0131klar\u0131nda Tan\u0131 ve Takip. Derman Medical Pub. 2015, 148-163.","journal-title":"Derman Medical Pub"},{"key":"ref8","article-title":"Advantages of MAG3 kit with respect to the DTPA kit for the children having urological and nephrological problems","volume":"42","author":"Okumu\u015f","year":"2016","unstructured":"Okumu\u015f, E, Erdogan M. Advantages of MAG3 kit with respect to the DTPA kit for the children having urological and nephrological problems . Sel\u00e7uk \u00dcniversitesi Fen Fak\u00fcltesi Fen Dergisi. 2016, 42:57-63.","journal-title":"Sel\u00e7uk \u00dcniversitesi Fen Fak\u00fcltesi Fen Dergisi"},{"key":"ref9","article-title":"Dynamic and diuretic renal scintigraphy","volume":"2","author":"Torun N","year":"2011","unstructured":"Torun N, \u00dcst\u00fcn F, Altun G. Dynamic and diuretic renal scintigraphy. Turk Urol Sem. 2011, 2:96-103.","journal-title":"Turk Urol Sem"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4274\/nts.galenos.2019.0024","article-title":"The role of nuclear medicine in pediatric hydronephrosis","volume":"5","author":"\u00d6zcan Z","year":"2019","unstructured":"\u00d6zcan Z. The role of nuclear medicine in pediatric hydronephrosis. Nucl Med Semin. 2019, 5:173-178. 10.4274\/nts.galenos.2019.0024","journal-title":"Nucl Med Semin"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/bju.14781","article-title":"Value of supranormal function on (99m) Tc-mercaptoacetyltriglycine renal scan in paediatric patients with obstructive hydronephrosis","volume":"124","author":"Mart\u00edn-Sol\u00e9 O","year":"2019","unstructured":"Mart\u00edn-Sol\u00e9 O, Soria-Gondek A, P\u00e9rez-Bert\u00f3lez S, Paredes P, Tarrado X, Garc\u00eda-Aparicio L. Value of supranormal function on (99m) Tc-mercaptoacetyltriglycine renal scan in paediatric patients with obstructive hydronephrosis. BJU Int. 2019, 124:842-848. 10.1111\/bju.14781","journal-title":"BJU Int"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(01)66322-5","article-title":"Increased renal function in kidneys with ureteropelvic junction obstruction: fact or artifact? Assessment by quantitative single photon emission computerized tomography of dimercapto-succinic acid uptake by the kidneys","volume":"155","author":"Groshar D","year":"1996","unstructured":"Groshar D, Issaq E, Nativ O, Livne PM. Increased renal function in kidneys with ureteropelvic junction obstruction: fact or artifact? Assessment by quantitative single photon emission computerized tomography of dimercapto-succinic acid uptake by the kidneys. J Urol. 1996, 155:844-846. 10.1016\/s0022-5347(01)66322-5","journal-title":"J Urol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-008-0908-8","article-title":"Comparison of differential renal function using technetium-99m mercaptoacetyltriglycine (MAG3) and technetium-99m dimercaptosuccinic acid (DMSA) renography in a paediatric population","volume":"38","author":"Ritchie G","year":"2008","unstructured":"Ritchie G, Wilkinson AG, Prescott RJ. Comparison of differential renal function using technetium-99m mercaptoacetyltriglycine (MAG3) and technetium-99m dimercaptosuccinic acid (DMSA) renography in a paediatric population. Pediatr Radiol. 2008, 38:857-862. 10.1007\/s00247-008-0908-8","journal-title":"Pediatr Radiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/RLU.0b013e3182443f68","article-title":"Renal cortical imaging in children: 99mTc MAG3 versus 99mTc DMSA","volume":"37","author":"Othman S","year":"2012","unstructured":"Othman S, Al-Hawas A, Al-Maqtari R. Renal cortical imaging in children: 99mTc MAG3 versus 99mTc DMSA. Clin Nucl Med. 2012, 37:351-355. 10.1097\/RLU.0b013e3182443f68","journal-title":"Clin Nucl Med"},{"key":"ref15","article-title":"","author":"Ba\u015ftu\u011f F","year":"1990","unstructured":"Ba\u015ftu\u011f F, Dursun I, T\u00fclpar S, et al.. \u00c7ocuk Nefroloji Derne\u011fi El Kitab\u0131. D\u00fc\u015f\u00fcnsel R, Ba\u015ftu\u011f F (ed): Klinik ve Pratik Yakla\u015f\u0131mlar, Ankara; 1990. http:\/\/www.cocuknefroloji.org\/site\/\/kitap\/detail\/1\/cocUk-nefroloji-el-kitabi-%E2%80%93-klinik-pratik-yaklasimlar.html."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/iju.14207","article-title":"Pediatric congenital hydronephrosis (ureteropelvic junction obstruction): medical management guide","volume":"27","author":"Kohno M","year":"2020","unstructured":"Kohno M, Ogawa T, Kojima Y, et al.. Pediatric congenital hydronephrosis (ureteropelvic junction obstruction): medical management guide. Int J Urol. 2020, 27:369-376. 10.1111\/iju.14207","journal-title":"Int J Urol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2013.03.041","article-title":"Predicting the clinical outcome of antenatally detected unilateral pelviureteric junction stenosis","volume":"82","author":"Duong HP","year":"2013","unstructured":"Duong HP, Piepsz A, Collier F, et al.. Predicting the clinical outcome of antenatally detected unilateral pelviureteric junction stenosis. Urology. 2013, 82:691-696. 10.1016\/j.urology.2013.03.041","journal-title":"Urology"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.5222\/JTAPS.2016.055","article-title":"Uretero-pelvic junction obstruction","volume":"30","author":"Onen A","year":"2016","unstructured":"Onen A. Uretero-pelvic junction obstruction. Turkish J Pediat Surg. 2016, 30:55-79. 10.5222\/JTAPS.2016.055","journal-title":"Turkish J Pediat Surg"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.09.2986","article-title":"Renal measurements, including length, parenchymal thickness, and medullary pyramid thickness, in healthy children: what are the normative ultrasound values?","volume":"194","author":"Kadioglu A","year":"2010","unstructured":"Kadioglu A. Renal measurements, including length, parenchymal thickness, and medullary pyramid thickness, in healthy children: what are the normative ultrasound values?. AJR Am J Roentgenol. 2010, 194:509-515. 10.2214\/AJR.09.2986","journal-title":"AJR Am J Roentgenol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-004-1708-5","article-title":"Optimised tracer-dependent dosage cards to obtain weight-independent effective doses","volume":"32","author":"Jacobs F","year":"2005","unstructured":"Jacobs F, Thierens H, Piepsz A, Bacher K, Van de Wiele C, Ham H, Dierckx RA. Optimised tracer-dependent dosage cards to obtain weight-independent effective doses. Eur J Nucl Med Mol Imaging. 2005, 32:581-588. 10.1007\/s00259-004-1708-5","journal-title":"Eur J Nucl Med Mol Imaging"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.14366\/usg.15073","article-title":"Ultrasonography of hydronephrosis in the newborn: a practical review","volume":"35","author":"Choi YH","year":"2016","unstructured":"Choi YH, Cheon JE, Kim WS, Kim IO. Ultrasonography of hydronephrosis in the newborn: a practical review. Ultrasonography. 2016, 35:198-211. 10.14366\/usg.15073","journal-title":"Ultrasonography"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/s0022-5347(17)47521-5","article-title":"The prognosis of surgically treated congenital hydronephrosis after diagnosis in utero","volume":"134","author":"Thorup J","year":"1985","unstructured":"Thorup J, Mortensen T, Diemer H, Johnsen A, Nielsen OH. The prognosis of surgically treated congenital hydronephrosis after diagnosis in utero. J Urol. 1985, 134:914-917. 10.1016\/s0022-5347(17)47521-5","journal-title":"J Urol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00467-004-1498-9","article-title":"Outcome of patients with antenatally detected pelviureteric junction obstruction","volume":"19","author":"Ylinen E","year":"2004","unstructured":"Ylinen E, Ala-Houhala M, Wikstr\u00f6m S. Outcome of patients with antenatally detected pelviureteric junction obstruction. Pediatr Nephrol. 2004, 19:880-887. 10.1007\/s00467-004-1498-9","journal-title":"Pediatr Nephrol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.eursup.2012.01.004","article-title":"Ureteropelvic junction obstruction","volume":"11","author":"Hashim H","year":"2012","unstructured":"Hashim H, Woodhouse CR. Ureteropelvic junction obstruction. Euro Urol Suppl. 2012, 11:25-32. 10.1016\/j.eursup.2012.01.004","journal-title":"Euro Urol Suppl"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.4274\/jus.366","article-title":"Assessment of differential renal function in children with hydronephrosis: comparison of DMSA and MAG-3","volume":"2015","author":"Akbal C","year":"2015","unstructured":"Akbal C, Sahan A, Garayev A, Sekerci CA, Sulukaya M. Assessment of differential renal function in children with hydronephrosis: comparison of DMSA and MAG-3. J Urol Surg. 2015, 2015:129-134. 10.4274\/jus.366","journal-title":"J Urol Surg"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1046\/j.1464-4096.2001.woodward.2578.x","article-title":"Postnatal management of antenatal hydronephrosis","volume":"89","author":"Woodward M","year":"2002","unstructured":"Woodward M, Frank D. Postnatal management of antenatal hydronephrosis. BJU Int. 2002, 89:149-156. 10.1046\/j.1464-4096.2001.woodward.2578.x","journal-title":"BJU Int"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.17219\/acem\/59509","article-title":"Hydronephrosis in the course of ureteropelvic junction obstruction: An underestimated problem? Current opinions on the pathogenesis, diagnosis and treatment","volume":"26","author":"Krajewski W","year":"2017","unstructured":"Krajewski W, Wojciechowska J, Dembowski J, Zdrojowy R, Szyde\u0142ko T. Hydronephrosis in the course of ureteropelvic junction obstruction: An underestimated problem? Current opinions on the pathogenesis, diagnosis and treatment. Adv Clin Exp Med. 2017, 26:857-864. 10.17219\/acem\/59509","journal-title":"Adv Clin Exp Med"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3413\/nukmed-0056","article-title":"Effects of background substraction on differential kidney function measured by static scintigraphy with DMSA and dynamic scintigraphy with MAG 3","volume":"47","author":"Girotto N","year":"2008","unstructured":"Girotto N, Smokvina A, Grbac Ivankovi\u0107 S, Licul V. Effects of background substraction on differential kidney function measured by static scintigraphy with DMSA and dynamic scintigraphy with MAG 3. Nuklearmedizin. 2008, 47:43-47. 10.3413\/nukmed-0056","journal-title":"Nuklearmedizin"},{"key":"ref29","article-title":"[Advantages of the new radiopharmaceutic agent, 99mTC-mercaptoacetyltriglycine (99mTc-MAG3), in the diagnosis of kidneydiseases. A comparative study with 131I-OIH, 99mTc-DTPA and 99mTc-DMSA]","volume":"93","author":"Lepej J","year":"1992","unstructured":"Lepej J, Marosov\u00e1 A, Kliment J, Buchanec J, Svit\u00e1c J, Klisenbauer L. [Advantages of the new radiopharmaceutic agent, 99mTC-mercaptoacetyltriglycine (99mTc-MAG3), in the diagnosis of kidneydiseases. A comparative study with 131I-OIH, 99mTc-DTPA and 99mTc-DMSA]. Bratisl Lek Listy. 1992, 93:258-265.","journal-title":"Bratisl Lek Listy"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.4103\/iju.IJU_109_20","article-title":"Supranormal differential renal function in adults with ureteropelvic junction obstruction: Does it really exist?","volume":"36","author":"Elbaset MA","year":"2020","unstructured":"Elbaset MA, Ezzat O, Elgamal M, Sharaf MA, Elmeniar AM, Abdelhamid A, Osman Y. Supranormal differential renal function in adults with ureteropelvic junction obstruction: Does it really exist?. Indian J Urol. 2020, 36:205-211. 10.4103\/iju.IJU_109_20","journal-title":"Indian J Urol"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2016.07.016","article-title":"Comparative outcome analysis of children who underwent pyeloplasty for ureteropelvic junction obstruction associated with or without supranormal differential renal function","volume":"99","author":"Rickard M","year":"2017","unstructured":"Rickard M, Braga LH, Gandhi S, Oliveria JP, Demaria J, Lorenzo AJ. Comparative outcome analysis of children who underwent pyeloplasty for ureteropelvic junction obstruction associated with or without supranormal differential renal function. Urology. 2017, 99:210-214. 10.1016\/j.urology.2016.07.016","journal-title":"Urology"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1097\/00003072-200502000-00004","article-title":"Contradictory supranormal function in hydronephrotic kidneys: fact or artifact on pediatric MAG-3 renal scans?","volume":"30","author":"Inanir S","year":"2005","unstructured":"Inanir S, Biyikli N, Noshari O, et al.. Contradictory supranormal function in hydronephrotic kidneys: fact or artifact on pediatric MAG-3 renal scans?. Clin Nucl Med. 2005, 30:91-96. 10.1097\/00003072-200502000-00004","journal-title":"Clin Nucl Med"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.urology.2012.09.017","article-title":"Nature and fate of supranormal differential renal function: lessons from long-term follow-up after pyeloplasty","volume":"81","author":"Cho SY","year":"2013","unstructured":"Cho SY, Kim IS, Lee SB, Choi H, Park K. Nature and fate of supranormal differential renal function: lessons from long-term follow-up after pyeloplasty. Urology. 2013, 81:163-167. 10.1016\/j.urology.2012.09.017","journal-title":"Urology"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1097\/00006231-200202000-00006","article-title":"Effect of the size of regions of interest on the estimation of differential renal function in children with congenital hydronephrosis","volume":"23","author":"Gungor F","year":"2002","unstructured":"Gungor F, Anderson P, Gordon I. Effect of the size of regions of interest on the estimation of differential renal function in children with congenital hydronephrosis. Nucl Med Commun. 2002, 23:147-151. 10.1097\/00006231-200202000-00006","journal-title":"Nucl Med Commun"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.juro.2008.06.010","article-title":"The importance of obtaining conjugate views on renographic evaluation of large hydronephrotic kidneys: an in vitro and ex vivo analysis","volume":"180","author":"Pippi Salle JL","year":"2008","unstructured":"Pippi Salle JL, Cook A, Papanikolaou F, et al.. The importance of obtaining conjugate views on renographic evaluation of large hydronephrotic kidneys: an in vitro and ex vivo analysis. J Urol. 2008, 180:1559-1565. 10.1016\/j.juro.2008.06.010","journal-title":"J Urol"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1464-410X.2007.06774.x","article-title":"The change in renal function in the supranormal hydronephrotic kidney after pyeloplasty","volume":"99","author":"Song C","year":"2007","unstructured":"Song C, Park H, Park S, Moon KH, Kim KS. The change in renal function in the supranormal hydronephrotic kidney after pyeloplasty. BJU Int. 2007, 99:1483-1486. 10.1111\/j.1464-410X.2007.06774.x","journal-title":"BJU Int"},{"key":"ref37","article-title":"Value of supranormal function and renogram patterns on 99mTc-mercaptoacetyltriglycine scintigraphy in relation to the extent of hydronephrosis for predicting ureteropelvic junction obstruction in the newborn","volume":"44","author":"Moon DH","year":"2003","unstructured":"Moon DH, Park YS, Jun NL, et al.. Value of supranormal function and renogram patterns on 99mTc-mercaptoacetyltriglycine scintigraphy in relation to the extent of hydronephrosis for predicting ureteropelvic junction obstruction in the newborn. J Nucl Med. 2003, 44:725-731.","journal-title":"J Nucl Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/266738-determining-split-renal-function-in-children-with-ureteropelvic-junction-stenosis-technetium-99m-mercaptoacetyltriglycine-tc-99m-mag-3-or-technetium-99m-dimercaptosuccinic-acid-tc-99m-dmsa","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,22]],"date-time":"2024-07-22T08:52:29Z","timestamp":1721638349000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/266738-determining-split-renal-function-in-children-with-ureteropelvic-junction-stenosis-technetium-99m-mercaptoacetyltriglycine-tc-99m-mag-3-or-technetium-99m-dimercaptosuccinic-acid-tc-99m-dmsa"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,22]]},"references-count":37,"URL":"https:\/\/doi.org\/10.7759\/cureus.65075","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7,22]]}}}