{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,7,25]],"date-time":"2024-07-25T00:29:47Z","timestamp":1721867387624},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,7,24]]},"DOI":"10.7759\/cureus.65283","type":"journal-article","created":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T16:13:37Z","timestamp":1721837617000},"source":"Crossref","is-referenced-by-count":0,"title":["A Paradox Unveiled: A Case Report of Cerebral Infarctions in a Patient With Severe Thrombocytopenia"],"prefix":"10.7759","author":[{"given":"Volha","family":"Chapiolkina","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yemesrach  F","family":"Mekonen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nehemias","family":"Guevara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esmirna","family":"Perez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jorge","family":"Sanchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria C","family":"Tole","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivette","family":"Vigoda","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra010501","article-title":"Immune thrombocytopenic purpura","volume":"346","author":"Cines DB","year":"2002","unstructured":"Cines DB, Blanchette VS. Immune thrombocytopenic purpura. N Engl J Med. 2002, 346:995-1008. 10.1056\/NEJMra010501","journal-title":"N Engl J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1080\/13696998.2019.1669329","article-title":"Primary immune thrombocytopenia in US clinical practice: incidence and healthcare burden in first 12 months following diagnosis","volume":"23","author":"Weycker D","year":"2020","unstructured":"Weycker D, Hanau A, Hatfield M, et al.. Primary immune thrombocytopenia in US clinical practice: incidence and healthcare burden in first 12 months following diagnosis. J Med Econ. 2020, 23:184-92. 10.1080\/13696998.2019.1669329","journal-title":"J Med Econ"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14227","article-title":"Risk factors for bleeding, including platelet count threshold, in newly diagnosed immune thrombocytopenia adults","volume":"16","author":"Piel-Julian ML","year":"2018","unstructured":"Piel-Julian ML, Mah\u00e9vas M, Germain J, et al.. Risk factors for bleeding, including platelet count threshold, in newly diagnosed immune thrombocytopenia adults. J Thromb Haemost. 2018, 16:1830-42. 10.1111\/jth.14227","journal-title":"J Thromb Haemost"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.12869","article-title":"Twenty-year mortality of adult patients with primary immune thrombocytopenia: a Danish population-based cohort study","volume":"166","author":"Frederiksen H","year":"2014","unstructured":"Frederiksen H, Maegbaek ML, N\u00f8rgaard M. Twenty-year mortality of adult patients with primary immune thrombocytopenia: a Danish population-based cohort study. Br J Haematol. 2014, 166:260-7. 10.1111\/bjh.12869","journal-title":"Br J Haematol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/ejh.12777","article-title":"Thromboembolism in adults with primary immune thrombocytopenia: a systematic literature review and meta-analysis","volume":"97","author":"Doobaree IU","year":"2016","unstructured":"Doobaree IU, Nandigam R, Bennett D, Newland A, Provan D. Thromboembolism in adults with primary immune thrombocytopenia: a systematic literature review and meta-analysis. Eur J Haematol. 2016, 97:321-30. 10.1111\/ejh.12777","journal-title":"Eur J Haematol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12636","article-title":"Thrombotic risk in patients with primary immune thrombocytopenia is only mildly increased and explained by personal and treatment-related risk factors","volume":"12","author":"Ruggeri M","year":"2014","unstructured":"Ruggeri M, Tosetto A, Palandri F, et al.. Thrombotic risk in patients with primary immune thrombocytopenia is only mildly increased and explained by personal and treatment-related risk factors. J Thromb Haemost. 2014, 12:1266-73. 10.1111\/jth.12636","journal-title":"J Thromb Haemost"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58020211","article-title":"Immune thrombocytopenic purpura as a hemorrhagic versus thrombotic disease: an updated insight into pathophysiological mechanisms","volume":"58","author":"T\u0103rniceriu CC","year":"2022","unstructured":"T\u0103rniceriu CC, Hurjui LL, Florea ID, et al.. Immune thrombocytopenic purpura as a hemorrhagic versus thrombotic disease: an updated insight into pathophysiological mechanisms. Medicina (Kaunas). 2022, 58:211. 10.3390\/medicina58020211","journal-title":"Medicina (Kaunas)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2009-01-129155","article-title":"The ITP syndrome: pathogenic and clinical diversity","volume":"113","author":"Cines DB","year":"2009","unstructured":"Cines DB, Bussel JB, Liebman HA, Luning Prak ET. The ITP syndrome: pathogenic and clinical diversity. Blood. 2009, 113:6511-21. 10.1182\/blood-2009-01-129155","journal-title":"Blood"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1055\/s-0039-1683416","article-title":"Epidemiology and clinical manifestations of immune thrombocytopenia","volume":"39","author":"Kohli R","year":"2019","unstructured":"Kohli R, Chaturvedi S. Epidemiology and clinical manifestations of immune thrombocytopenia. Hamostaseologie. 2019, 39:238-49. 10.1055\/s-0039-1683416","journal-title":"Hamostaseologie"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.19070","article-title":"Complement in immune thrombocytopenia (ITP): the role of complement in refractory ITP","volume":"203","author":"Weitz IC","year":"2023","unstructured":"Weitz IC, Liebman HA. Complement in immune thrombocytopenia (ITP): the role of complement in refractory ITP. Br J Haematol. 2023, 203:96-100. 10.1111\/bjh.19070","journal-title":"Br J Haematol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.110.233056","article-title":"Microparticles in hemostasis and thrombosis","volume":"108","author":"Owens AP","year":"2011","unstructured":"Owens AP, Mackman N. Microparticles in hemostasis and thrombosis. Circ Res. 2011, 108:1284-97. 10.1161\/CIRCRESAHA.110.233056","journal-title":"Circ Res"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2009.018390","article-title":"Thromboembolic events among adult patients with primary immune thrombocytopenia in the United Kingdom General Practice Research Database","volume":"95","author":"Sarpatwari A","year":"2010","unstructured":"Sarpatwari A, Bennett D, Logie JW, et al.. Thromboembolic events among adult patients with primary immune thrombocytopenia in the United Kingdom General Practice Research Database. Haematologica. 2010, 95:1167-75. 10.3324\/haematol.2009.018390","journal-title":"Haematologica"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s12185-010-0636-3","article-title":"Comorbidities in patients with persistent or chronic immune thrombocytopenia","volume":"92","author":"Enger C","year":"2010","unstructured":"Enger C, Bennett D, Forssen U, Fogarty PF, McAfee AT. Comorbidities in patients with persistent or chronic immune thrombocytopenia. Int J Hematol. 2010, 92:289-95. 10.1007\/s12185-010-0636-3","journal-title":"Int J Hematol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/MOH.0b013e32833e77ee","article-title":"Clinical relevance of microparticles from platelets and megakaryocytes","volume":"17","author":"Italiano JE Jr","year":"2010","unstructured":"Italiano JE Jr, Mairuhu AT, Flaumenhaft R. Clinical relevance of microparticles from platelets and megakaryocytes. Curr Opin Hematol. 2010, 17:578-84. 10.1097\/MOH.0b013e32833e77ee","journal-title":"Curr Opin Hematol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-018-1649-7","article-title":"Management of antithrombotic therapy in adults with immune thrombocytopenia (ITP): a survey of ITP specialists and general hematologist-oncologists","volume":"46","author":"Pishko AM","year":"2018","unstructured":"Pishko AM, Misgav M, Cuker A, Cines DB, George JN, Vesely SK, Terrell DR. Management of antithrombotic therapy in adults with immune thrombocytopenia (ITP): a survey of ITP specialists and general hematologist-oncologists. J Thromb Thrombolysis. 2018, 46:24-30. 10.1007\/s11239-018-1649-7","journal-title":"J Thromb Thrombolysis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1017\/cjn.2020.138","article-title":"The clinical conundrum of managing ischemic stroke in patients with immune thrombocytopenia","volume":"48","author":"Alrohimi A","year":"2021","unstructured":"Alrohimi A, Purdy K, Alqarni M, et al.. The clinical conundrum of managing ischemic stroke in patients with immune thrombocytopenia. Can J Neurol Sci. 2021, 48:38-46. 10.1017\/cjn.2020.138","journal-title":"Can J Neurol Sci"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2017.03.021","article-title":"Intravenous thrombolysis for acute ischemic stroke in patients with thrombocytopenia","volume":"26","author":"Mowla A","year":"2017","unstructured":"Mowla A, Kamal H, Lail NS, et al.. Intravenous thrombolysis for acute ischemic stroke in patients with thrombocytopenia. J Stroke Cerebrovasc Dis. 2017, 26:1414-8. 10.1016\/j.jstrokecerebrovasdis.2017.03.021","journal-title":"J Stroke Cerebrovasc Dis"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/262644-a-paradox-unveiled-a-case-report-of-cerebral-infarctions-in-a-patient-with-severe-thrombocytopenia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,24]],"date-time":"2024-07-24T16:13:42Z","timestamp":1721837622000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/262644-a-paradox-unveiled-a-case-report-of-cerebral-infarctions-in-a-patient-with-severe-thrombocytopenia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,24]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.65283","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7,24]]}}}