{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T12:44:41Z","timestamp":1787748281953,"version":"build-2784847793"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,1]]},"DOI":"10.7759\/cureus.65918","type":"journal-article","created":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T07:47:32Z","timestamp":1722498452000},"source":"Crossref","is-referenced-by-count":2,"title":["Treatment of Infected Tibia Non-union Using a Novel Solid Intramedullary Nail Custom-Made for Antibiotic-Impregnated Cement Coating"],"prefix":"10.7759","author":[{"given":"Ashwin","family":"Deshmukh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Nair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shivappa","family":"Devarmani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ankit","family":"Barosani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"The infected nonunion of the tibia","author":"Toh CL","year":"1995","unstructured":"Toh CL, Jupiter JB. The infected nonunion of the tibia. Clin Orthop Relat Res. 1995, 176-91.","journal-title":"Clin Orthop Relat Res"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.5435\/00124635-200510000-00006","article-title":"Chronic posttraumatic osteomyelitis and infected nonunion of the tibia: Current management concepts","volume":"13","author":"Patzakis MJ","year":"2005","unstructured":"Patzakis MJ, Zalavras CG. Chronic posttraumatic osteomyelitis and infected nonunion of the tibia: Current management concepts. J Am Acad Orthop Surg. 2005, 13:417-27. 10.5435\/00124635-200510000-00006","journal-title":"J Am Acad Orthop Surg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/BCO.0b013e318230efcf","article-title":"Orthopaedic biofilm infections","volume":"22","author":"Stoodley P","year":"2011","unstructured":"Stoodley P, Ehrlich GD, Sedghizadeh PP, et al.. Orthopaedic biofilm infections. Curr Orthop Pract. 2011, 22:558-63. 10.1097\/BCO.0b013e318230efcf","journal-title":"Curr Orthop Pract"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1177\/03946320110241S223","article-title":"Antibiotic-coated nails in orthopedic and trauma surgery: State of the art","volume":"24","author":"Nizegorodcew T","year":"2011","unstructured":"Nizegorodcew T, Palmieri G, Marzetti E. Antibiotic-coated nails in orthopedic and trauma surgery: State of the art. Int J Immunopathol Pharmacol. 2011, 24:125-8. 10.1177\/03946320110241S223","journal-title":"Int J Immunopathol Pharmacol"},{"key":"ref5","article-title":"Antibiotic cement impregnated nailing in the management of infected nonunion of femur and tibia","volume":"26","author":"Dhanasekhar R","year":"2013","unstructured":"Dhanasekhar R, Jacob P, Francis J. Antibiotic cement impregnated nailing in the management of infected nonunion of femur and tibia. Kerala J Orthop. 2013, 26:93-7.","journal-title":"Kerala J Orthop"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0000000000002453","article-title":"Antibiotic cement-coated interlocked intramedullary nails for the treatment of infected nonunion after intramedullary nailing","volume":"37","author":"Zalikha AK","year":"2023","unstructured":"Zalikha AK, Sayeed Z, Stine SA, Bray R, Vaidya R. Antibiotic cement-coated interlocked intramedullary nails for the treatment of infected nonunion after intramedullary nailing. J Orthop Trauma. 2023, 37:e1-6. 10.1097\/BOT.0000000000002453","journal-title":"J Orthop Trauma"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.orthres.2004.11.006","article-title":"Infection resistance of unreamed solid, hollow slotted and cannulated intramedullary nails: An in-vivo experimental comparison","volume":"23","author":"Horn J","year":"2005","unstructured":"Horn J, Schlegel U, Krettek C, Ito K. Infection resistance of unreamed solid, hollow slotted and cannulated intramedullary nails: An in-vivo experimental comparison. J Orthop Res. 2005, 23:810-5. 10.1016\/j.orthres.2004.11.006","journal-title":"J Orthop Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s00402-007-0315-x","article-title":"Use of antibiotic cement rod to treat intramedullary infection after nailing: Preliminary study in 19 patients","volume":"127","author":"Qiang Z","year":"2007","unstructured":"Qiang Z, Jun PZ, Jie XJ, Hang L, Bing LJ, Cai LF. Use of antibiotic cement rod to treat intramedullary infection after nailing: Preliminary study in 19 patients. Arch Orthop Trauma Surg. 2007, 127:945-51. 10.1007\/s00402-007-0315-x","journal-title":"Arch Orthop Trauma Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/BOT.0b013e31803ea9e6","article-title":"Antibiotic cement-coated interlocking nail for the treatment of infected nonunions and segmental bone defects","volume":"21","author":"Thonse R","year":"2007","unstructured":"Thonse R, Conway J. Antibiotic cement-coated interlocking nail for the treatment of infected nonunions and segmental bone defects. J Orthop Trauma. 2007, 21:258-68. 10.1097\/BOT.0b013e31803ea9e6","journal-title":"J Orthop Trauma"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/01.bot.0000161542.93624.8d","article-title":"Infection after reamed intramedullary nailing of the tibia: A case series review","volume":"19","author":"Petrisor B","year":"2005","unstructured":"Petrisor B, Anderson S, Court-Brown CM. Infection after reamed intramedullary nailing of the tibia: A case series review. J Orthop Trauma. 2005, 19:437-41. 10.1097\/01.bot.0000161542.93624.8d","journal-title":"J Orthop Trauma"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/230949900401200215","article-title":"Unreamed interlocking nailing in open fractures of tibia","volume":"12","author":"Joshi D","year":"2004","unstructured":"Joshi D, Ahmed A, Krishna L, Lal Y. Unreamed interlocking nailing in open fractures of tibia. J Orthop Surg (Hong Kong). 2004, 12:216-21. 10.1177\/230949900401200215","journal-title":"J Orthop Surg (Hong Kong)"},{"key":"ref12","doi-asserted-by":"crossref","DOI":"10.1097\/00003086-198411000-00014","article-title":"Antibiotic-loaded acrylic cement: Current concepts","author":"Buchholz HW","year":"1984","unstructured":"Buchholz HW, Elson RA, Heinert K. Antibiotic-loaded acrylic cement: Current concepts. Clin Orthop Relat Res. 1984, 96-108.","journal-title":"Clin Orthop Relat Res"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000143571.18892.8d","article-title":"Local antibiotic therapy in the treatment of open fractures and osteomyelitis","volume":"427","author":"Zalavras CG","year":"2004","unstructured":"Zalavras CG, Patzakis MJ, Holtom P. Local antibiotic therapy in the treatment of open fractures and osteomyelitis. Clin Orthop Relat Res. 2004, 427:86-93. 10.1097\/01.blo.0000143571.18892.8d","journal-title":"Clin Orthop Relat Res"},{"key":"ref14","article-title":"Antibiotic bead chains","author":"Klemm KW","year":"1993","unstructured":"Klemm KW. Antibiotic bead chains. Clin Orthop Relat Res. 1993, 63-76.","journal-title":"Clin Orthop Relat Res"},{"key":"ref15","doi-asserted-by":"crossref","DOI":"10.1097\/00003086-198611000-00020","article-title":"Infection following intramedullary nailing of long bones. Diagnosis and management","author":"Patzakis MJ","year":"1986","unstructured":"Patzakis MJ, Wilkins J, Wiss DA. Infection following intramedullary nailing of long bones. Diagnosis and management. Clin Orthop Relat Res. 1986, 182-91.","journal-title":"Clin Orthop Relat Res"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/01.blo.0000150462.41498.fe","article-title":"The treatment of chronic open osteomyelitis of the tibia in adults","volume":"433","author":"Beals RK","year":"2005","unstructured":"Beals RK, Bryant RE. The treatment of chronic open osteomyelitis of the tibia in adults. Clin Orthop Relat Res. 2005, 433:212-7. 10.1097\/01.blo.0000150462.41498.fe","journal-title":"Clin Orthop Relat Res"},{"key":"ref17","article-title":"Complications of external skeletal fixation","author":"Green SA","year":"1983","unstructured":"Green SA. Complications of external skeletal fixation. Clin Orthop Relat Res. 1983, 109-16.","journal-title":"Clin Orthop Relat Res"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/00005131-200211000-00007","article-title":"Intramedullary infections treated with antibiotic cement rods: Preliminary results in nine cases","volume":"16","author":"Paley D","year":"2002","unstructured":"Paley D, Herzenberg JE. Intramedullary infections treated with antibiotic cement rods: Preliminary results in nine cases. J Orthop Trauma. 2002, 16:723-9. 10.1097\/00005131-200211000-00007","journal-title":"J Orthop Trauma"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/00003086-199608000-00034","article-title":"Persistence of bacteria on antibiotic loaded acrylic depots. A reason for caution","volume":"329","author":"Kendall RW","year":"1996","unstructured":"Kendall RW, Duncan CP, Smith JA, Ngui-Yen JH. Persistence of bacteria on antibiotic loaded acrylic depots. A reason for caution. Clin Orthop Relat Res. 1996, 329:273-80. 10.1097\/00003086-199608000-00034","journal-title":"Clin Orthop Relat Res"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/0020-1383(96)89028-0","article-title":"Infection after intramedullary nailing: An experimental investigation on rabbits","volume":"27","author":"Melcher GA","year":"1996","unstructured":"Melcher GA, Hauke C, Metzdorf A, Perren SM, Printzen G, Schlegel U, Ziegler WJ. Infection after intramedullary nailing: An experimental investigation on rabbits. Injury. 1996, 27:23-6. 10.1016\/0020-1383(96)89028-0","journal-title":"Injury"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-010-1626-8","article-title":"Increased antibiotic release from a bone cement containing bacterial cellulose","volume":"469","author":"Mori R","year":"2011","unstructured":"Mori R, Nakai T, Enomoto K. Increased antibiotic release from a bone cement containing bacterial cellulose. Clin Orthop Relat Res. 2011, 469:600-6. 10.1007\/s11999-010-1626-8","journal-title":"Clin Orthop Relat Res"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/273068-treatment-of-infected-tibia-non-union-using-a-novel-solid-intramedullary-nail-custom-made-for-antibiotic-impregnated-cement-coating","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T07:47:36Z","timestamp":1722498456000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/273068-treatment-of-infected-tibia-non-union-using-a-novel-solid-intramedullary-nail-custom-made-for-antibiotic-impregnated-cement-coating"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,1]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.65918","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,1]]}}}