{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,26]],"date-time":"2026-03-26T20:06:59Z","timestamp":1774555619763,"version":"3.50.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,4]]},"DOI":"10.7759\/cureus.66116","type":"journal-article","created":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T11:23:08Z","timestamp":1722770588000},"source":"Crossref","is-referenced-by-count":1,"title":["The Diagnostic Yield of Laboratory Tests in Chronic Constipation in Adults"],"prefix":"10.7759","author":[{"given":"Ali  A","family":"Ramadhan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aveen","family":"Mustafa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramadhan","family":"Issa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hassan","family":"Bapeer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.03.035","article-title":"Rome IV-functional GI disorders: disorders of gut-brain interaction","volume":"150","author":"Drossman DA","year":"2016","unstructured":"Drossman DA, Hasler WL. Rome IV-functional GI disorders: disorders of gut-brain interaction. Gastroenterology. 2016, 150:1257-61. 10.1053\/j.gastro.2016.03.035","journal-title":"Gastroenterology"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2011.164","article-title":"Prevalence of, and risk factors for, chronic idiopathic constipation in the community: systematic review and meta-analysis","volume":"106","author":"Suares NC","year":"2011","unstructured":"Suares NC, Ford AC. Prevalence of, and risk factors for, chronic idiopathic constipation in the community: systematic review and meta-analysis. Am J Gastroenterol. 2011, 106:1582-91; quiz 1581, 1592. 10.1038\/ajg.2011.164","journal-title":"Am J Gastroenterol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/nmo.12252","article-title":"Assessment of esophageal dysfunction and symptoms during and after a standardized test meal: development and clinical validation of a new methodology utilizing high-resolution manometry","volume":"26","author":"Sweis R","year":"2014","unstructured":"Sweis R, Anggiansah A, Wong T, Brady G, Fox M. Assessment of esophageal dysfunction and symptoms during and after a standardized test meal: development and clinical validation of a new methodology utilizing high-resolution manometry. Neurogastroenterol Motil. 2014, 26:215-28. 10.1111\/nmo.12252","journal-title":"Neurogastroenterol Motil"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0800670","article-title":"A placebo-controlled trial of prucalopride for severe chronic constipation","volume":"358","author":"Camilleri M","year":"2008","unstructured":"Camilleri M, Kerstens R, Rykx A, Vandeplassche L. A placebo-controlled trial of prucalopride for severe chronic constipation. N Engl J Med. 2008, 358:2344-54. 10.1056\/NEJMoa0800670","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.5056\/jnm.2012.18.4.373","article-title":"Rectal hyposensitivity","volume":"18","author":"Burgell RE","year":"2012","unstructured":"Burgell RE, Scott SM. Rectal hyposensitivity. J Neurogastroenterol Motil. 2012, 18:373-84. 10.5056\/jnm.2012.18.4.373","journal-title":"J Neurogastroenterol Motil"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10081738","article-title":"Current overview on clinical management of chronic constipation","volume":"10","author":"W\u0142odarczyk J","year":"2021","unstructured":"W\u0142odarczyk J, Wa\u015bniewska A, Fichna J, Dziki A, Dziki \u0141, W\u0142odarczyk M. Current overview on clinical management of chronic constipation. J Clin Med. 2021, 10:1738. 10.3390\/jcm10081738","journal-title":"J Clin Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.10.029","article-title":"American Gastroenterological Association medical position statement on constipation","volume":"144","author":"Bharucha AE","year":"2013","unstructured":"Bharucha AE, Dorn SD, Lembo A, Pressman A. American Gastroenterological Association medical position statement on constipation. Gastroenterology. 2013, 144:211-7. 10.1053\/j.gastro.2012.10.029","journal-title":"Gastroenterology"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002227","article-title":"American Gastroenterological Association-American College of Gastroenterology clinical practice guideline: pharmacological management of chronic idiopathic constipation","volume":"118","author":"Chang L","year":"2023","unstructured":"Chang L, Chey WD, Imdad A, et al.. American Gastroenterological Association-American College of Gastroenterology clinical practice guideline: pharmacological management of chronic idiopathic constipation. Am J Gastroenterol. 2023, 118:936-54. 10.14309\/ajg.0000000000002227","journal-title":"Am J Gastroenterol"},{"key":"ref9","unstructured":"Rome Foundation. Rome IV diagnostic criteria. (2021). Accessed: June 5, 2024: https:\/\/theromefoundation.org\/rome-iv\/rome-iv-criteria\/."},{"key":"ref10","article-title":"World Health Organization: The SuRF Report 2: The Surveillance of Risk Factors Report Series (SuRF). (2005). Accessed: July 5","author":"World Health Organization: . (2005). Accessed: July 5","year":"2005","unstructured":"World Health Organization. . (2005). Accessed: July 5: The SuRF Report 2: The Surveillance of Chronic Disease Risk Factors Country-level Data and Comparable Estimates. World Health Organization, Geneva, Switzerland; 2005. https:\/\/iris.who.int\/bitstream\/handle\/10665\/43190\/9241593024_eng.pdf."},{"key":"ref11","article-title":"Mosby\u2019s Diagnostic & Laboratory Test Reference","author":"Pagana KD","year":"2022","unstructured":"Pagana KD, Pagana TJ, Pagana TN. Mosby\u2019s Diagnostic & Laboratory Test Reference. Elsevier, St. Louis, MO; 2022."},{"key":"ref12","unstructured":"Endocrine Society. Vitamin D for the prevention of disease guideline resources. (2024). Accessed: July 5, 2024: https:\/\/www.endocrine.org\/clinical-practice-guidelines\/vitamin-d-for-prevention-of-disease."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2019.12.034","article-title":"Mechanisms, evaluation, and management of chronic constipation","volume":"158","author":"Bharucha AE","year":"2020","unstructured":"Bharucha AE, Lacy BE. Mechanisms, evaluation, and management of chronic constipation. Gastroenterology. 2020, 158:1232-49.e3. 10.1053\/j.gastro.2019.12.034","journal-title":"Gastroenterology"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2013.03.016","article-title":"Chronic constipation: a critical review","volume":"45","author":"Basilisco G","year":"2013","unstructured":"Basilisco G, Coletta M. Chronic constipation: a critical review. Dig Liver Dis. 2013, 45:886-93. 10.1016\/j.dld.2013.03.016","journal-title":"Dig Liver Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2016.02.013","article-title":"Chronic Constipation","volume":"45","author":"Brenner DM","year":"2016","unstructured":"Brenner DM, Shah M. Chronic Constipation. Gastroenterol Clin North Am. 2016, 45:205-16. 10.1016\/j.gtc.2016.02.013","journal-title":"Gastroenterol Clin North Am"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2013.73","article-title":"Association of low dietary intake of fiber and liquids with constipation: evidence from the National Health and Nutrition Examination Survey","volume":"108","author":"Markland AD","year":"2013","unstructured":"Markland AD, Palsson O, Goode PS, Burgio KL, Busby-Whitehead J, Whitehead WE. Association of low dietary intake of fiber and liquids with constipation: evidence from the National Health and Nutrition Examination Survey. Am J Gastroenterol. 2013, 108:796-803. 10.1038\/ajg.2013.73","journal-title":"Am J Gastroenterol"},{"key":"ref17","doi-asserted-by":"crossref","DOI":"10.1111\/j.1572-0241.2003.07591.x","article-title":"Association between physical activity, fiber intake, and other lifestyle variables and constipation in a study of women","volume":"98","author":"Dukas L","year":"2003","unstructured":"Dukas L, Willett WC, Giovannucci EL. Association between physical activity, fiber intake, and other lifestyle variables and constipation in a study of women. Am J Gastroenterol. 2003, 98:1790-6.","journal-title":"Am J Gastroenterol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000035124","article-title":"Adverse physiological effects of smoking cessation on the gastrointestinal tract: a review","volume":"102","author":"Mahyoub MA","year":"2023","unstructured":"Mahyoub MA, Al-Qurmoti S, Rai AA, Abbas M, Jebril M, Alnaggar M, He S. Adverse physiological effects of smoking cessation on the gastrointestinal tract: a review. Medicine (Baltimore). 2023, 102:e35124. 10.1097\/MD.0000000000035124","journal-title":"Medicine (Baltimore)"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1080\/07315724.2020.1727380","article-title":"Risk factors for constipation in adults: a cross-sectional study","volume":"39","author":"Yurtda\u015f G","year":"2020","unstructured":"Yurtda\u015f G, Acar-Tek N, Akbulut G, Cemali \u00d6, Arslan N, Beyaz Co\u015fkun A, Zengin FH. Risk factors for constipation in adults: a cross-sectional study. J Am Coll Nutr. 2020, 39:713-9. 10.1080\/07315724.2020.1727380","journal-title":"J Am Coll Nutr"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/945165","article-title":"Yield and cost of performing screening tests for constipation in children","volume":"27","author":"Chogle A","year":"2013","unstructured":"Chogle A, Saps M. Yield and cost of performing screening tests for constipation in children. Can J Gastroenterol. 2013, 27:e35-8. 10.1155\/2013\/945165","journal-title":"Can J Gastroenterol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v25.i14.1729","article-title":"Chronic functional constipation is strongly linked to vitamin D deficiency","volume":"25","author":"Panarese A","year":"2019","unstructured":"Panarese A, Pesce F, Porcelli P, et al.. Chronic functional constipation is strongly linked to vitamin D deficiency. World J Gastroenterol. 2019, 25:1729-40. 10.3748\/wjg.v25.i14.1729","journal-title":"World J Gastroenterol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/274898-the-diagnostic-yield-of-laboratory-tests-in-chronic-constipation-in-adults","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,4]],"date-time":"2024-08-04T11:23:15Z","timestamp":1722770595000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/274898-the-diagnostic-yield-of-laboratory-tests-in-chronic-constipation-in-adults"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,4]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.66116","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,4]]}}}