{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T06:26:20Z","timestamp":1787984780838,"version":"build-2784847793"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,10]]},"DOI":"10.7759\/cureus.66584","type":"journal-article","created":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T15:57:27Z","timestamp":1723305447000},"source":"Crossref","is-referenced-by-count":1,"title":["Relationship of C-reactive Protein\/Serum Albumin Ratio and qPitt Bacteremia Score With An All-Cause In-Hospital Mortality in Patients With Bloodstream Infections"],"prefix":"10.7759","author":[{"given":"Eyad J","family":"Al Shaqri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Balkhair","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-020-05950-6","article-title":"Bloodstream infections in critically ill patients: An expert statement","volume":"46","author":"Timsit JF","year":"2020","unstructured":"Timsit JF, Rupp\u00e9 E, Barbier F, Tabah A, Bassetti M. Bloodstream infections in critically ill patients: An expert statement. Intensive Care Med. 2020, 46:266-84. 10.1007\/s00134-020-05950-6","journal-title":"Intensive Care Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2019.10.031","article-title":"Burden of bacterial bloodstream infection-a brief update on epidemiology and significance of multidrug-resistant pathogens","volume":"26","author":"Kern WV","year":"2020","unstructured":"Kern WV, Rieg S. Burden of bacterial bloodstream infection-a brief update on epidemiology and significance of multidrug-resistant pathogens. Clin Microbiol Infect. 2020, 26:151-7. 10.1016\/j.cmi.2019.10.031","journal-title":"Clin Microbiol Infect"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30696-2","article-title":"Sepsis and septic shock","volume":"392","author":"Cecconi M","year":"2018","unstructured":"Cecconi M, Evans L, Levy M, Rhodes A. Sepsis and septic shock. Lancet. 2018, 392:75-87. 10.1016\/S0140-6736(18)30696-2","journal-title":"Lancet"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaa461","article-title":"epidemiology and risk factors associated with mortality in consecutive patients with bacterial bloodstream infection: Impact of MDR and XDR bacteria","volume":"7","author":"Santoro A","year":"2020","unstructured":"Santoro A, Franceschini E, Meschiari M, et al.. epidemiology and risk factors associated with mortality in consecutive patients with bacterial bloodstream infection: Impact of MDR and XDR bacteria. Open Forum Infect Dis. 2020, 7:ofaa461. 10.1093\/ofid\/ofaa461","journal-title":"Open Forum Infect Dis"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.629671","article-title":"Clinical profile, prognostic factors, and outcome prediction in hospitalized patients with bloodstream infection: Results from a 10-year prospective multicenter study","volume":"8","author":"Jin L","year":"2021","unstructured":"Jin L, Zhao C, Li H, Wang R, Wang Q, Wang H. Clinical profile, prognostic factors, and outcome prediction in hospitalized patients with bloodstream infection: Results from a 10-year prospective multicenter study. Front Med. 2021, 8:629671. 10.3389\/fmed.2021.629671","journal-title":"Front Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm7100333","article-title":"The C-reactive protein\/albumin ratio as a predictor of mortality in critically ill patients","volume":"7","author":"Park JE","year":"2018","unstructured":"Park JE, Chung KS, Song JH, et al.. The C-reactive protein\/albumin ratio as a predictor of mortality in critically ill patients. J Clin Med. 2018, 7:333. 10.3390\/jcm7100333","journal-title":"J Clin Med"},{"key":"ref7","article-title":"C Reactive Protein","author":"Nehring SM","year":"2024","unstructured":"Nehring SM, Goyal A, Patel BC. C Reactive Protein. StatPearls [Internet]. StatPearls Publishing, Treasure Island, FL; 2024."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2147\/JIR.S321074","article-title":"Predictive value of C-reactive protein-to-albumin ratio for neonatal sepsis","volume":"14","author":"Li T","year":"2021","unstructured":"Li T, Li X, Wei Y, et al.. Predictive value of C-reactive protein-to-albumin ratio for neonatal sepsis. J Inflamm Res. 2021, 14:3207-15. 10.2147\/JIR.S321074","journal-title":"J Inflamm Res"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.2174\/1381612821666150302115025","article-title":"Review: modifications of human serum albumin and their binding effect","volume":"21","author":"Lee P","year":"2015","unstructured":"Lee P, Wu X. Review: modifications of human serum albumin and their binding effect. Curr Pharm Des. 2015, 21:1862-5. 10.2174\/1381612821666150302115025","journal-title":"Curr Pharm Des"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.14744\/TurkPediatriArs.2020.99076","article-title":"CRP\/albumin ratio: A promising marker of gram-negative bacteremia in late-onset neonatal sepsis","volume":"56","author":"G\u00fcne\u015f H","year":"2021","unstructured":"G\u00fcne\u015f H, Yurttutan S, \u00c7obanu\u015fa\u011f\u0131 M, Do\u011faner A. CRP\/albumin ratio: A promising marker of gram-negative bacteremia in late-onset neonatal sepsis. Turk Arch Pediatr. 2021, 56:32-6. 10.14744\/TurkPediatriArs.2020.99076","journal-title":"Turk Arch Pediatr"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33361-7","article-title":"Clinical usefulness of C-reactive protein to albumin ratio in predicting 30-day mortality in critically ill patients: A retrospective analysis","volume":"8","author":"Oh TK","year":"2018","unstructured":"Oh TK, Song IA, Lee JH. Clinical usefulness of C-reactive protein to albumin ratio in predicting 30-day mortality in critically ill patients: A retrospective analysis. Sci Rep. 2018, 8:14977. 10.1038\/s41598-018-33361-7","journal-title":"Sci Rep"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz535","article-title":"Resilience of the Pitt Bacteremia Score: 3 Decades and counting","volume":"70","author":"Al-Hasan MN","year":"2020","unstructured":"Al-Hasan MN, Baddour LM. Resilience of the Pitt Bacteremia Score: 3 Decades and counting. Clin Infect Dis. 2020, 70:1834-6. 10.1093\/cid\/ciz535","journal-title":"Clin Infect Dis"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/1469-0691.12085","article-title":"Predictive scoring model of mortality in Gram-negative bloodstream infection","volume":"19","author":"Al-Hasan MN","year":"2013","unstructured":"Al-Hasan MN, Lahr BD, Eckel-Passow JE, Baddour LM. Predictive scoring model of mortality in Gram-negative bloodstream infection. Clin Microbiol Infect. 2013, 19:948-54. 10.1111\/1469-0691.12085","journal-title":"Clin Microbiol Infect"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz528","article-title":"The Pitt Bacteremia Score predicts mortality in nonbacteremic infections","volume":"70","author":"Henderson H","year":"2020","unstructured":"Henderson H, Luterbach CL, Cober E, et al.. The Pitt Bacteremia Score predicts mortality in nonbacteremic infections. Clin Infect Dis. 2020, 70:1826-33. 10.1093\/cid\/ciz528","journal-title":"Clin Infect Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajic.2018.06.019","article-title":"Epidemiology and risk factors for mortality in bloodstream infections: A single-center retrospective study in Japan","volume":"46","author":"Hattori H","year":"2018","unstructured":"Hattori H, Maeda M, Nagatomo Y, et al.. Epidemiology and risk factors for mortality in bloodstream infections: A single-center retrospective study in Japan. Am J Infect Control. 2018, 46:e75-9. 10.1016\/j.ajic.2018.06.019","journal-title":"Am J Infect Control"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.02429-21","article-title":"Prevalence and mortality associated with bloodstream organisms: A population-wide retrospective cohort study","volume":"60","author":"Verway M","year":"2022","unstructured":"Verway M, Brown KA, Marchand-Austin A, et al.. Prevalence and mortality associated with bloodstream organisms: A population-wide retrospective cohort study. J Clin Microbiol. 2022, 60:e0242921. 10.1128\/jcm.02429-21","journal-title":"J Clin Microbiol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/tmi.13650","article-title":"The impact of ageing on the incidence and mortality rate of bloodstream infection: A hospital-based case-cohort study in a tertiary public hospital of Brazil","volume":"26","author":"da Silva NC","year":"2021","unstructured":"da Silva NC, da Rocha JA, do Valle FM, Silva AS, Ehrlich S, Martins IS. The impact of ageing on the incidence and mortality rate of bloodstream infection: A hospital-based case-cohort study in a tertiary public hospital of Brazil. Trop Med Int Health. 2021, 26:1276-84. 10.1111\/tmi.13650","journal-title":"Trop Med Int Health"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231911845","article-title":"Cellular Senescence in Immunity against Infections","volume":"23","author":"Marrella V","year":"2022","unstructured":"Marrella V, Facoetti A, Cassani B. Cellular Senescence in Immunity against Infections. Int J Mol Sci. 2022, 23:11845. 10.3390\/ijms231911845","journal-title":"Int J Mol Sci"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijregi.2023.04.005","article-title":"Access- and non-access-related infections among patients receiving haemodialysis: Experience of an academic centre in Oman","volume":"7","author":"Himali NA","year":"2023","unstructured":"Himali NA, Abdelrahman A, Suleimani YM, Balkhair A, Al-Zakwani I. Access- and non-access-related infections among patients receiving haemodialysis: Experience of an academic centre in Oman. IJID Reg. 2023, 7:252-5. 10.1016\/j.ijregi.2023.04.005","journal-title":"IJID Reg"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.22037\/aaem. v12i1.2148","article-title":"Comparison of qSOFA, SIRS, NEWS and REWS Scores in predicting severity and 28-day mortality of older suspected sepsis cases; a prognostic accuracy study","volume":"3","author":"Sanguanwit P","year":"2023","unstructured":"Sanguanwit P, Thudsaringkarnsakul W, Angkoontassaneeyarat C, Watcharakitpaisan S. Comparison of qSOFA, SIRS, NEWS and REWS Scores in predicting severity and 28-day mortality of older suspected sepsis cases; a prognostic accuracy study. Arch Acad Emerg Med. 2023, 3:e3. 10.22037\/aaem. v12i1.2148","journal-title":"Arch Acad Emerg Med"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S420569","article-title":"Prediction of 30-day mortality using the quick Pitt Bacteremia Score in hospitalized patients with Klebsiella pneumoniae infection","volume":"16","author":"Su C","year":"2023","unstructured":"Su C, Tsai IT, Lai CH, Lin KH, Chen CC, Hsu YC. Prediction of 30-day mortality using the quick Pitt Bacteremia Score in hospitalized patients with Klebsiella pneumoniae infection. Infect Drug Resist. 2023, 16:4807-15. 10.2147\/IDR.S420569","journal-title":"Infect Drug Resist"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-42352-2","article-title":"Effects of C-reactive protein trajectories of critically ill patients with sepsis on in-hospital mortality rate","volume":"13","author":"Jiang X","year":"2023","unstructured":"Jiang X, Zhang C, Pan Y, Cheng X, Zhang W. Effects of C-reactive protein trajectories of critically ill patients with sepsis on in-hospital mortality rate. Sci Rep. 2023, 13:15223. 10.1038\/s41598-023-42352-2","journal-title":"Sci Rep"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.2147\/CLEP.S396247","article-title":"Albumin level is associated with short-term and long-term outcomes in sepsis patients admitted in the ICU: A large public database retrospective research","volume":"15","author":"Cao Y","year":"2023","unstructured":"Cao Y, Su Y, Guo C, He L, Ding N. Albumin level is associated with short-term and long-term outcomes in sepsis patients admitted in the ICU: A large public database retrospective research. Clin Epidemiol. 2023, 15:263-73. 10.2147\/CLEP.S396247","journal-title":"Clin Epidemiol"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-42601-4","article-title":"C-reactive protein-to-albumin ratio as a biomarker in patients with sepsis: A novel LASSO-COX based prognostic nomogram","volume":"13","author":"Zhou X","year":"2023","unstructured":"Zhou X, Fu S, Wu Y, Guo Z, Dian W, Sun H, Liao Y. C-reactive protein-to-albumin ratio as a biomarker in patients with sepsis: A novel LASSO-COX based prognostic nomogram. Sci Rep. 2023, 13:15309. 10.1038\/s41598-023-42601-4","journal-title":"Sci Rep"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1080\/13685538.2023.2261540","article-title":"The prognostic value of C-reactive protein to albumin ratio in patients with sepsis: A systematic review and meta-analysis","volume":"26","author":"Liu Y","year":"2023","unstructured":"Liu Y, Gao Y, Liang B, Liang Z. The prognostic value of C-reactive protein to albumin ratio in patients with sepsis: A systematic review and meta-analysis. Aging Male. 2023, 26:2261540. 10.1080\/13685538.2023.2261540","journal-title":"Aging Male"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s15010-019-01277-7","article-title":"Derivation of a quick Pitt bacteremia score to predict mortality in patients with Gram-negative bloodstream infection","volume":"47","author":"Battle SE","year":"2019","unstructured":"Battle SE, Augustine MR, Watson CM, et al.. Derivation of a quick Pitt bacteremia score to predict mortality in patients with Gram-negative bloodstream infection. Infection. 2019, 47:571-8. 10.1007\/s15010-019-01277-7","journal-title":"Infection"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/282319-relationship-of-c-reactive-proteinserum-albumin-ratio-and-qpitt-bacteremia-score-with-an-all-cause-in-hospital-mortality-in-patients-with-bloodstream-infections","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,10]],"date-time":"2024-08-10T15:57:30Z","timestamp":1723305450000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/282319-relationship-of-c-reactive-proteinserum-albumin-ratio-and-qpitt-bacteremia-score-with-an-all-cause-in-hospital-mortality-in-patients-with-bloodstream-infections"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,10]]},"references-count":26,"URL":"https:\/\/doi.org\/10.7759\/cureus.66584","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,10]]}}}