{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T18:06:30Z","timestamp":1781546790335,"version":"3.54.5"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,20]]},"DOI":"10.7759\/cureus.67259","type":"journal-article","created":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T07:04:28Z","timestamp":1724137468000},"source":"Crossref","is-referenced-by-count":1,"title":["Demographic and Microbiological Profile of Corneal Ulcers in Eastern India"],"prefix":"10.7759","author":[{"given":"Neha","family":"Shilpy","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhishek","family":"Chandra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harshita","family":"Lal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sarswati","family":".","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ritu","family":"Dixit","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Govind V","family":"Khalkho","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Diksha","family":"Sareen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.81.8.622","article-title":"Corneal ulceration in the developing world--a silent epidemic","volume":"81","author":"Whitcher JP","year":"1997","unstructured":"Whitcher JP, Srinivasan M. Corneal ulceration in the developing world--a silent epidemic. Br J Ophthalmol. 1997, 81:622-3. 10.1136\/bjo.81.8.622","journal-title":"Br J Ophthalmol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.86.11.1211","article-title":"Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis","volume":"86","author":"Leck AK","year":"2002","unstructured":"Leck AK, Thomas PA, Hagan M, et al.. Aetiology of suppurative corneal ulcers in Ghana and south India, and epidemiology of fungal keratitis. Br J Ophthalmol. 2002, 86:1211-5. 10.1136\/bjo.86.11.1211","journal-title":"Br J Ophthalmol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318156caf2","article-title":"Risk factors and causative organisms in microbial keratitis","volume":"27","author":"Green M","year":"2008","unstructured":"Green M, Apel A, Stapleton F. Risk factors and causative organisms in microbial keratitis. Cornea. 2008, 27:22-7. 10.1097\/ICO.0b013e318156caf2","journal-title":"Cornea"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2013.1718","article-title":"Fluoroquinolone treatment and susceptibility of isolates from bacterial keratitis","volume":"131","author":"Ray KJ","year":"2013","unstructured":"Ray KJ, Prajna L, Srinivasan M, et al.. Fluoroquinolone treatment and susceptibility of isolates from bacterial keratitis. JAMA Ophthalmol. 2013, 131:310-3. 10.1001\/jamaophthalmol.2013.1718","journal-title":"JAMA Ophthalmol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1001\/archophthalmol.2011.45","article-title":"Topical fluoroquinolone use as a risk factor for in vitro fluoroquinolone resistance in ocular cultures","volume":"129","author":"Fintelmann RE","year":"2011","unstructured":"Fintelmann RE, Hoskins EN, Lietman TM, Keenan JD, Gaynor BD, Cevallos V, Acharya NR. Topical fluoroquinolone use as a risk factor for in vitro fluoroquinolone resistance in ocular cultures. Arch Ophthalmol. 2011, 129:399-402. 10.1001\/archophthalmol.2011.45","journal-title":"Arch Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1590\/S0036-46652015000700011","article-title":"Susceptibility test for fungi: clinical and laboratorial correlations in medical mycology","volume":"57 Suppl 19","author":"Alastruey-Izquierdo A","year":"2015","unstructured":"Alastruey-Izquierdo A, Melhem MS, Bonfietti LX, Rodriguez-Tudela JL. Susceptibility test for fungi: clinical and laboratorial correlations in medical mycology. Rev Inst Med Trop Sao Paulo. 2015, 57 Suppl 19:57-64. 10.1590\/S0036-46652015000700011","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"ref7","article-title":"Development of in vitro susceptibility testing criteria and quality control parameters, 5th ed","author":"Wikler MA","year":"2018","unstructured":"Wikler MA, Lewis JS, Moeck G, Nicolau DP, Satlin, M. Development of in vitro susceptibility testing criteria and quality control parameters, 5th ed. Clinical and Laboratory Standards Institute, Wayne, PA; 2018."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.31653","article-title":"Microbiological profile in patients having keratitis in a tertiary care hospital in India","volume":"14","author":"Pramanick P","year":"2022","unstructured":"Pramanick P, Sengupta M, Banerjee M, Ghosh S, Mitra AN, Chakraborty M, Sengupta M. Microbiological profile in patients having keratitis in a tertiary care hospital in India. Cureus. 2022, 14:e31653. 10.7759\/cureus.31653","journal-title":"Cureus"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-020-01339-3","article-title":"Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance","volume":"35","author":"Ting DS","year":"2021","unstructured":"Ting DS, Ho CS, Deshmukh R, Said DG, Dua HS. Infectious keratitis: an update on epidemiology, causative microorganisms, risk factors, and antimicrobial resistance. Eye (Lond). 2021, 35:1084-101. 10.1038\/s41433-020-01339-3","journal-title":"Eye (Lond)"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.2009.169607","article-title":"Geographic variations in microbial keratitis: an analysis of the peer-reviewed literature","volume":"95","author":"Shah A","year":"2011","unstructured":"Shah A, Sachdev A, Coggon D, Hossain P. Geographic variations in microbial keratitis: an analysis of the peer-reviewed literature. Br J Ophthalmol. 2011, 95:762-7. 10.1136\/bjo.2009.169607","journal-title":"Br J Ophthalmol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-018-0085-4","article-title":"A 10-year analysis of microbiological profiles of microbial keratitis: the North East England Study","volume":"32","author":"Ting DS","year":"2018","unstructured":"Ting DS, Settle C, Morgan SJ, Baylis O, Ghosh S. A 10-year analysis of microbiological profiles of microbial keratitis: the North East England Study. Eye (Lond). 2018, 32:1416-7. 10.1038\/s41433-018-0085-4","journal-title":"Eye (Lond)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-019-0463-6","article-title":"An 11-year analysis of microbial keratitis in the South West of England using brain-heart infusion broth","volume":"33","author":"Tavassoli S","year":"2019","unstructured":"Tavassoli S, Nayar G, Darcy K, Grzeda M, Luck J, Williams OM, Tole D. An 11-year analysis of microbial keratitis in the South West of England using brain-heart infusion broth. Eye (Lond). 2019, 33:1619-25. 10.1038\/s41433-019-0463-6","journal-title":"Eye (Lond)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2020-316128","article-title":"12-year analysis of incidence, microbiological profiles and in vitro antimicrobial susceptibility of infectious keratitis: the Nottingham Infectious Keratitis Study","volume":"105","author":"Ting DS","year":"2021","unstructured":"Ting DS, Ho CS, Cairns J, et al.. 12-year analysis of incidence, microbiological profiles and in vitro antimicrobial susceptibility of infectious keratitis: the Nottingham Infectious Keratitis Study. Br J Ophthalmol. 2021, 105:328-33. 10.1136\/bjophthalmol-2020-316128","journal-title":"Br J Ophthalmol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000001390","article-title":"Bacterial keratitis in Toronto: a 16-year review of the microorganisms isolated and the resistance patterns observed","volume":"36","author":"Tam AL","year":"2017","unstructured":"Tam AL, C\u00f4t\u00e9 E, Saldanha M, Lichtinger A, Slomovic AR. Bacterial keratitis in Toronto: a 16-year review of the microorganisms isolated and the resistance patterns observed. Cornea. 2017, 36:1528-34. 10.1097\/ICO.0000000000001390","journal-title":"Cornea"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s10792-011-9441-0","article-title":"Microbial keratitis at a referral center in Brazil","volume":"31","author":"Cariello AJ","year":"2011","unstructured":"Cariello AJ, Passos RM, Yu MC, Hofling-Lima AL. Microbial keratitis at a referral center in Brazil. Int Ophthalmol. 2011, 31:197-204. 10.1007\/s10792-011-9441-0","journal-title":"Int Ophthalmol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000428","article-title":"Trends in microbiological and antibiotic sensitivity patterns in infectious keratitis: 10-year experience in Mexico City","volume":"34","author":"Hernandez-Camarena JC","year":"2015","unstructured":"Hernandez-Camarena JC, Graue-Hernandez EO, Ortiz-Casas M, et al.. Trends in microbiological and antibiotic sensitivity patterns in infectious keratitis: 10-year experience in Mexico City. Cornea. 2015, 34:778-85. 10.1097\/ICO.0000000000000428","journal-title":"Cornea"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165223","article-title":"Trends of bacterial keratitis culture isolates in Jerusalem: a 13-years analysis","volume":"11","author":"Politis M","year":"2016","unstructured":"Politis M, Wajnsztajn D, Rosin B, Block C, Solomon A. Trends of bacterial keratitis culture isolates in Jerusalem: a 13-years analysis. PLoS One. 2016, 11:e0165223. 10.1371\/journal.pone.0165223","journal-title":"PLoS One"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2018-312881","article-title":"Queensland microbial keratitis database: 2005-2015","volume":"103","author":"Green M","year":"2019","unstructured":"Green M, Carnt N, Apel A, Stapleton F. Queensland microbial keratitis database: 2005-2015. Br J Ophthalmol. 2019, 103:1481-6. 10.1136\/bjophthalmol-2018-312881","journal-title":"Br J Ophthalmol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/ceo.13672","article-title":"Antimicrobial resistance trends in bacterial keratitis over 5\u2009years in Sydney, Australia","volume":"48","author":"Cabrera-Aguas M","year":"2020","unstructured":"Cabrera-Aguas M, Khoo P, George CR, Lahra MM, Watson SL. Antimicrobial resistance trends in bacterial keratitis over 5\u2009years in Sydney, Australia. Clin Exp Ophthalmol. 2020, 48:183-91. 10.1111\/ceo.13672","journal-title":"Clin Exp Ophthalmol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/181564","article-title":"Spectrum of bacterial keratitis at a tertiary eye care centre in India","volume":"2013","author":"Kaliamurthy J","year":"2013","unstructured":"Kaliamurthy J, Kalavathy CM, Parmar P, Nelson Jesudasan CA, Thomas PA. Spectrum of bacterial keratitis at a tertiary eye care centre in India. Biomed Res Int. 2013, 2013:181564. 10.1155\/2013\/181564","journal-title":"Biomed Res Int"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2014-305000","article-title":"Trends in bacterial and fungal keratitis in south India, 2002-2012","volume":"99","author":"Lalitha P","year":"2015","unstructured":"Lalitha P, Prajna NV, Manoharan G, et al.. Trends in bacterial and fungal keratitis in south India, 2002-2012. Br J Ophthalmol. 2015, 99:192-4. 10.1136\/bjophthalmol-2014-305000","journal-title":"Br J Ophthalmol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S206831","article-title":"Nine-year analysis of isolated pathogens and antibiotic susceptibilities of microbial keratitis from a large referral eye center in southern China","volume":"12","author":"Lin L","year":"2019","unstructured":"Lin L, Duan F, Yang Y, Lou B, Liang L, Lin X. Nine-year analysis of isolated pathogens and antibiotic susceptibilities of microbial keratitis from a large referral eye center in southern China. Infect Drug Resist. 2019, 12:1295-302. 10.2147\/IDR.S206831","journal-title":"Infect Drug Resist"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1097\/00003226-200210000-00002","article-title":"Evaluation of corneal scraping smear examination methods in the diagnosis of bacterial and fungal keratitis: a survey of eight years of laboratory experience","volume":"21","author":"Sharma S","year":"2002","unstructured":"Sharma S, Kunimoto DY, Gopinathan U, Athmanathan S, Garg P, Rao GN. Evaluation of corneal scraping smear examination methods in the diagnosis of bacterial and fungal keratitis: a survey of eight years of laboratory experience. Cornea. 2002, 21:643-7. 10.1097\/00003226-200210000-00002","journal-title":"Cornea"},{"key":"ref24","article-title":"Fungal keratitis","author":"Castano G","year":"2020","unstructured":"Castano G, Elnahry AG, Mada PK. Fungal keratitis. StatPearls. StatPearls (ed): StatPearls Publishing, Treasure Island (FL); 2020."},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_928_19","article-title":"Demographic details, risk factors, microbiological profile, and clinical outcomes of pediatric infectious keratitis cases in North India","volume":"68","author":"Singh M","year":"2020","unstructured":"Singh M, Gour A, Gandhi A, Mathur U, Farooqui JH. Demographic details, risk factors, microbiological profile, and clinical outcomes of pediatric infectious keratitis cases in North India. Indian J Ophthalmol. 2020, 68:434-40. 10.4103\/ijo.IJO_928_19","journal-title":"Indian J Ophthalmol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.4103\/2008-322X.194071","article-title":"Microbial profile of corneal ulcers in a tertiary care hospital in south India","volume":"11","author":"Ranjini CY","year":"2016","unstructured":"Ranjini CY, Waddepally VV. Microbial profile of corneal ulcers in a tertiary care hospital in south India. J Ophthalmic Vis Res. 2016, 11:363-7. 10.4103\/2008-322X.194071","journal-title":"J Ophthalmic Vis Res"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000000431","article-title":"Antibiotic resistance in the treatment of Staphylococcus aureus keratitis: a 20-year review","volume":"34","author":"Chang VS","year":"2015","unstructured":"Chang VS, Dhaliwal DK, Raju L, Kowalski RP. Antibiotic resistance in the treatment of Staphylococcus aureus keratitis: a 20-year review. Cornea. 2015, 34:698-703. 10.1097\/ICO.0000000000000431","journal-title":"Cornea"},{"key":"ref28","article-title":"Minimum inhibitory concentrations and resistance for selected antimicrobial agents (including imipenem, linezolid and tigecycline) of bacteria obtained from eye infections","volume":"64","author":"Galvis V","year":"2020","unstructured":"Galvis V, Tello A, S\u00e1nchez W, Camacho P, Villarreal D, Garc\u00eda D. Minimum inhibitory concentrations and resistance for selected antimicrobial agents (including imipenem, linezolid and tigecycline) of bacteria obtained from eye infections. Rom J Ophthalmol. 2020, 64:269-79.","journal-title":"Rom J Ophthalmol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/279050-demographic-and-microbiological-profile-of-corneal-ulcers-in-eastern-india","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,20]],"date-time":"2024-08-20T07:04:31Z","timestamp":1724137471000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/279050-demographic-and-microbiological-profile-of-corneal-ulcers-in-eastern-india"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,20]]},"references-count":28,"URL":"https:\/\/doi.org\/10.7759\/cureus.67259","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,20]]}}}