{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T14:40:36Z","timestamp":1724337636583},"reference-count":14,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,22]]},"DOI":"10.7759\/cureus.67489","type":"journal-article","created":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T13:47:11Z","timestamp":1724334431000},"source":"Crossref","is-referenced-by-count":0,"title":["Titin As the Culprit Behind Dilated Cardiomyopathy: A Case Series of Three Cases and a Comprehensive Literature Review"],"prefix":"10.7759","author":[{"given":"Binay K","family":"Panjiyar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikita","family":"Changlani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Saroj K","family":"Jha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sanam W","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Omar","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.cellbio.18.012502.105840","article-title":"Striated muscle cytoarchitecture: an intricate web of form and function","volume":"18","author":"Clark KA","year":"2002","unstructured":"Clark KA, McElhinny AS, Beckerle MC, Gregorio CC. Striated muscle cytoarchitecture: an intricate web of form and function. Annu Rev Cell Dev Biol. 2002, 18:637-706. 10.1146\/annurev.cellbio.18.012502.105840","journal-title":"Annu Rev Cell Dev Biol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1110186","article-title":"Truncations of titin causing dilated cardiomyopathy","volume":"366","author":"Herman DS","year":"2012","unstructured":"Herman DS, Lam L, Taylor MR, et al.. Truncations of titin causing dilated cardiomyopathy. N Engl J Med. 2012, 366:619-28. 10.1056\/NEJMoa1110186","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3010134","article-title":"Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease","volume":"7","author":"Roberts AM","year":"2015","unstructured":"Roberts AM, Ware JS, Herman DS, et al.. Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease. Sci Transl Med. 2015, 7:270-6. 10.1126\/scitranslmed.3010134","journal-title":"Sci Transl Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3719","article-title":"Titin-truncating variants affect heart function in disease cohorts and the general population","volume":"49","author":"Schafer S","year":"2017","unstructured":"Schafer S, de Marvao A, Adami E, et al.. Titin-truncating variants affect heart function in disease cohorts and the general population. Nat Genet. 2017, 49:46-53. 10.1038\/ng.3719","journal-title":"Nat Genet"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-018-0039-z","article-title":"Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG)","volume":"20","author":"Hershberger RE","year":"2018","unstructured":"Hershberger RE, Givertz MM, Ho CY, et al.. Genetic evaluation of cardiomyopathy: a clinical practice resource of the American College of Medical Genetics and Genomics (ACMG). Genet Med. 2018, 20:899-909. 10.1038\/s41436-018-0039-z","journal-title":"Genet Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0169007","article-title":"Titin truncating variants in dilated cardiomyopathy - prevalence and genotype-phenotype correlations","volume":"12","author":"Franaszczyk M","year":"2017","unstructured":"Franaszczyk M, Chmielewski P, Truszkowska G, et al.. Titin truncating variants in dilated cardiomyopathy - prevalence and genotype-phenotype correlations. PLoS One. 2017, 12:7. 10.1371\/journal.pone.0169007","journal-title":"PLoS One"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGEN.122.003788","article-title":"Prevalence and clinical consequences of multiple pathogenic variants in dilated cardiomyopathy","volume":"16","author":"Stroeks SL","year":"2023","unstructured":"Stroeks SL, Lunde IG, Hellebrekers DM, et al.. Prevalence and clinical consequences of multiple pathogenic variants in dilated cardiomyopathy. Circ Genom Precis Med. 2023, 16:107-14. 10.1161\/CIRCGEN.122.003788","journal-title":"Circ Genom Precis Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2013.1363","article-title":"Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy","volume":"309","author":"Gulati A","year":"2013","unstructured":"Gulati A, Jabbour A, Ismail TF, et al.. Association of fibrosis with mortality and sudden cardiac death in patients with nonischemic dilated cardiomyopathy. JAMA. 2013, 309:896-908. 10.1001\/jama.2013.1363","journal-title":"JAMA"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.16","article-title":"Long-term prognostic impact of therapeutic strategies in patients with idiopathic dilated cardiomyopathy: changing mortality over the last 30 years","volume":"16","author":"Merlo M","year":"2014","unstructured":"Merlo M, Pivetta A, Pinamonti B, et al.. Long-term prognostic impact of therapeutic strategies in patients with idiopathic dilated cardiomyopathy: changing mortality over the last 30 years. Eur J Heart Fail. 2014, 16:317-24. 10.1002\/ejhf.16","journal-title":"Eur J Heart Fail"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCIMAGING.114.002411","article-title":"Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy","volume":"7","author":"Captur G","year":"2014","unstructured":"Captur G, Lopes LR, Mohun TJ, et al.. Prediction of sarcomere mutations in subclinical hypertrophic cardiomyopathy. Circ Cardiovasc Imaging. 2014, 7:863-71. 10.1161\/CIRCIMAGING.114.002411","journal-title":"Circ Cardiovasc Imaging"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.15252\/emmm.201505047","article-title":"Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy","volume":"7","author":"Gramlich M","year":"2015","unstructured":"Gramlich M, Pane LS, Zhou Q, et al.. Antisense-mediated exon skipping: a therapeutic strategy for titin-based dilated cardiomyopathy. EMBO Mol Med. 2015, 7:562-76. 10.15252\/emmm.201505047","journal-title":"EMBO Mol Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(14)61282-4","article-title":"Left ventricular non-compaction cardiomyopathy","volume":"386","author":"Towbin JA","year":"2015","unstructured":"Towbin JA, Lorts A, Jefferies JL. Left ventricular non-compaction cardiomyopathy. Lancet. 2015, 386:813-25. 10.1016\/S0140-6736(14)61282-4","journal-title":"Lancet"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/nrcardio.2013.105","article-title":"Dilated cardiomyopathy: the complexity of a diverse genetic architecture","volume":"10","author":"Hershberger RE","year":"2013","unstructured":"Hershberger RE, Hedges DJ, Morales A. Dilated cardiomyopathy: the complexity of a diverse genetic architecture. Nat Rev Cardiol. 2013, 10:531-47. 10.1038\/nrcardio.2013.105","journal-title":"Nat Rev Cardiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehac180","article-title":"A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy","volume":"43","author":"Cadrin-Tourigny J","year":"2022","unstructured":"Cadrin-Tourigny J, Bosman LP, Nozza A, et al.. A new prediction model for ventricular arrhythmias in arrhythmogenic right ventricular cardiomyopathy. Eur Heart J. 2022, 43:e1-9. 10.1093\/eurheartj\/ehac180","journal-title":"Eur Heart J"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/264700-titin-as-the-culprit-behind-dilated-cardiomyopathy-a-case-series-of-three-cases-and-a-comprehensive-literature-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,22]],"date-time":"2024-08-22T13:47:59Z","timestamp":1724334479000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/264700-titin-as-the-culprit-behind-dilated-cardiomyopathy-a-case-series-of-three-cases-and-a-comprehensive-literature-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,22]]},"references-count":14,"URL":"https:\/\/doi.org\/10.7759\/cureus.67489","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,22]]}}}