{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,26]],"date-time":"2026-06-26T08:21:24Z","timestamp":1782462084277,"version":"3.54.5"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,25]]},"DOI":"10.7759\/cureus.67739","type":"journal-article","created":{"date-parts":[[2024,8,25]],"date-time":"2024-08-25T16:06:45Z","timestamp":1724602005000},"source":"Crossref","is-referenced-by-count":2,"title":["Thymoma With Myasthenia Gravis: A Study of Two Cases"],"prefix":"10.7759","author":[{"given":"Aravindan","family":"Kumaravel","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sulochana","family":"Sonti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Thoracic Tumours: WHO Classification of Tumours, 5th Edition, Volume 5","author":"WHO Classification of Tumors Editorial Board","year":"2021","unstructured":"WHO Classification of Tumors Editorial Board. Thoracic Tumours: WHO Classification of Tumours, 5th Edition, Volume 5. International Agency for Research on Cancer, Lyon, France; 2021."},{"key":"ref2","article-title":"Rosai and Ackerman\u2019s Surgical Pathology, Eleventh Edition","author":"Goldblum JR","year":"2017","unstructured":"Goldblum JR, Lamps LW, McKenney JK. Rosai and Ackerman\u2019s Surgical Pathology, Eleventh Edition. Goldblum JR, Lamps LW, McKenney JK, Myers JL (ed): Elsevier, Philadelphia, PA; 2017."},{"key":"ref3","article-title":"Specialist Training in Oncology","author":"Ajithkumar","year":"2011","unstructured":"Ajithkumar, Hatcher H. Specialist Training in Oncology. Ajithkumar TV, Hatcher H (ed): Mosby, Maryland Heights, MO; 2011."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000654","article-title":"The 2015 World Health Organization classification of tumors of the thymus: continuity and changes","volume":"10","author":"Marx A","year":"2015","unstructured":"Marx A, Chan JK, Coindre JM, et al.. The 2015 World Health Organization classification of tumors of the thymus: continuity and changes. J Thorac Oncol. 2015, 10:1383-95. 10.1097\/JTO.0000000000000654","journal-title":"J Thorac Oncol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31818e105c","article-title":"Thymoma: a focus on current therapeutic management","volume":"4","author":"Girard N","year":"2009","unstructured":"Girard N, Mornex F, Van Houtte P, Cordier JF, van Schil P. Thymoma: a focus on current therapeutic management. J Thorac Oncol. 2009, 4:119-26. 10.1097\/JTO.0b013e31818e105c","journal-title":"J Thorac Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3988\/jcn.2012.8.3.161","article-title":"Incidence of thymoma in myasthenia gravis: a systematic review","volume":"8","author":"Mao ZF","year":"2012","unstructured":"Mao ZF, Mo XA, Qin C, Lai YR, Hackett ML. Incidence of thymoma in myasthenia gravis: a systematic review. J Clin Neurol. 2012, 8:161-9. 10.3988\/jcn.2012.8.3.161","journal-title":"J Clin Neurol"},{"key":"ref7","article-title":"Mills and Sternberg's Diagnostic Surgical Pathology, Seventh Edition","author":"Longacre TA","year":"2022","unstructured":"Longacre TA. Mills and Sternberg's Diagnostic Surgical Pathology, Seventh Edition. Longacre TA, Greenson JK, Hornick JL, Reuter VE (ed): LWW, Baltimore, MD; 2022."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000297","article-title":"Histologic classification of thymoma: a practical guide for routine cases","volume":"9","author":"den Bakker MA","year":"2014","unstructured":"den Bakker MA, Roden AC, Marx A, Marino M. Histologic classification of thymoma: a practical guide for routine cases. J Thorac Oncol. 2014, 9:S125-30. 10.1097\/JTO.0000000000000297","journal-title":"J Thorac Oncol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0b013e31821e8cff","article-title":"The Masaoka-Koga stage classification for thymic malignancies: clarification and definition of terms","volume":"6","author":"Detterbeck FC","year":"2011","unstructured":"Detterbeck FC, Nicholson AG, Kondo K, Van Schil P, Moran C. The Masaoka-Koga stage classification for thymic malignancies: clarification and definition of terms. J Thorac Oncol. 2011, 6:S1710-6. 10.1097\/JTO.0b013e31821e8cff","journal-title":"J Thorac Oncol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13215254","article-title":"Masaoka-Koga and TNM staging system in thymic epithelial tumors: prognostic comparison and the role of the number of involved structures","volume":"13","author":"Chiappetta M","year":"2021","unstructured":"Chiappetta M, Lococo F, Pogliani L, et al.. Masaoka-Koga and TNM staging system in thymic epithelial tumors: prognostic comparison and the role of the number of involved structures. Cancers (Basel). 2021, 13:5254. 10.3390\/cancers13215254","journal-title":"Cancers (Basel)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/JTO.0000000000000300","article-title":"Paraneoplastic disorders in thymoma patients","volume":"9","author":"Evoli A","year":"2014","unstructured":"Evoli A, Lancaster E. Paraneoplastic disorders in thymoma patients. J Thorac Oncol. 2014, 9:S143-7. 10.1097\/JTO.0000000000000300","journal-title":"J Thorac Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2013.03.007","article-title":"The different roles of the thymus in the pathogenesis of the various myasthenia gravis subtypes","volume":"12","author":"Marx A","year":"2013","unstructured":"Marx A, Pfister F, Schalke B, Saruhan-Direskeneli G, Melms A, Str\u00f6bel P. The different roles of the thymus in the pathogenesis of the various myasthenia gravis subtypes. Autoimmun Rev. 2013, 12:875-84. 10.1016\/j.autrev.2013.03.007","journal-title":"Autoimmun Rev"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2004.06.090","article-title":"Thymoma and myasthenia gravis: a clinical study of 1,089 patients from Japan","volume":"79","author":"Kondo K","year":"2005","unstructured":"Kondo K, Monden Y. Thymoma and myasthenia gravis: a clinical study of 1,089 patients from Japan. Ann Thorac Surg. 2005, 79:219-24. 10.1016\/j.athoracsur.2004.06.090","journal-title":"Ann Thorac Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-829585","article-title":"Pathophysiology of myasthenia gravis","volume":"24","author":"Hughes BW","year":"2004","unstructured":"Hughes BW, Moro De Casillas ML, Kaminski HJ. Pathophysiology of myasthenia gravis. Semin Neurol. 2004, 24:21-30. 10.1055\/s-2004-829585","journal-title":"Semin Neurol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10112235","article-title":"Myasthenia gravis: epidemiology, pathophysiology and clinical manifestations","volume":"10","author":"Dresser L","year":"2021","unstructured":"Dresser L, Wlodarski R, Rezania K, Soliven B. Myasthenia gravis: epidemiology, pathophysiology and clinical manifestations. J Clin Med. 2021, 10:2235. 10.3390\/jcm10112235","journal-title":"J Clin Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/mus.20030","article-title":"Clinical evaluation and management of myasthenia gravis","volume":"29","author":"Keesey JC","year":"2004","unstructured":"Keesey JC. Clinical evaluation and management of myasthenia gravis. Muscle Nerve. 2004, 29:484-505. 10.1002\/mus.20030","journal-title":"Muscle Nerve"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.00212","article-title":"Autoantibody specificities in myasthenia gravis; implications for improved diagnostics and therapeutics","volume":"11","author":"Lazaridis K","year":"2020","unstructured":"Lazaridis K, Tzartos SJ. Autoantibody specificities in myasthenia gravis; implications for improved diagnostics and therapeutics. Front Immunol. 2020, 11:212. 10.3389\/fimmu.2020.00212","journal-title":"Front Immunol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-016-8045-z","article-title":"Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the guidelines of the German Neurological Society","volume":"263","author":"Melzer N","year":"2016","unstructured":"Melzer N, Ruck T, Fuhr P, et al.. Clinical features, pathogenesis, and treatment of myasthenia gravis: a supplement to the guidelines of the German Neurological Society. J Neurol. 2016, 263:1473-94. 10.1007\/s00415-016-8045-z","journal-title":"J Neurol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3892\/ol.2016.4528","article-title":"Myasthenia gravis in patients with thymoma affects survival rate following extended thymectomy","volume":"11","author":"Zhang Z","year":"2016","unstructured":"Zhang Z, Cui Y, Jia R, Xue L, Liang H. Myasthenia gravis in patients with thymoma affects survival rate following extended thymectomy. Oncol Lett. 2016, 11:4177-82. 10.3892\/ol.2016.4528","journal-title":"Oncol Lett"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/474512","article-title":"Thymoma in myasthenia gravis: from diagnosis to treatment","volume":"2011","author":"Romi F","year":"2011","unstructured":"Romi F. Thymoma in myasthenia gravis: from diagnosis to treatment. Autoimmune Dis. 2011, 2011:474512. 10.4061\/2011\/474512","journal-title":"Autoimmune Dis"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.14744\/nci.2016.60352","article-title":"The effect of myasthenia gravis as a prognostic factor in thymoma treatment","volume":"3","author":"Aydemir B","year":"2016","unstructured":"Aydemir B. The effect of myasthenia gravis as a prognostic factor in thymoma treatment. North Clin Istanb. 2016, 3:194-200. 10.14744\/nci.2016.60352","journal-title":"North Clin Istanb"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3389\/fsurg.2022.726673","article-title":"Pathological features and prognosis of thymoma with or without myasthenia gravis","volume":"9","author":"Zhang Y","year":"2022","unstructured":"Zhang Y, Yu L, Ke J. Pathological features and prognosis of thymoma with or without myasthenia gravis. Front Surg. 2022, 9:726673. 10.3389\/fsurg.2022.726673","journal-title":"Front Surg"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3904\/kjim.1996.11.1.40","article-title":"Prognostic factors of patients with thymoma","volume":"11","author":"Lee WS","year":"1996","unstructured":"Lee WS, Heo DS, Bang YJ, et al.. Prognostic factors of patients with thymoma. Korean J Intern Med. 1996, 11:40-9. 10.3904\/kjim.1996.11.1.40","journal-title":"Korean J Intern Med"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/278366-thymoma-with-myasthenia-gravis-a-study-of-two-cases","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,25]],"date-time":"2024-08-25T16:06:49Z","timestamp":1724602009000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/278366-thymoma-with-myasthenia-gravis-a-study-of-two-cases"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,25]]},"references-count":23,"URL":"https:\/\/doi.org\/10.7759\/cureus.67739","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,25]]}}}