{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,26]],"date-time":"2026-08-26T07:32:40Z","timestamp":1787729560456,"version":"build-2784847793"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,31]]},"DOI":"10.7759\/cureus.68292","type":"journal-article","created":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T12:34:35Z","timestamp":1725107675000},"source":"Crossref","is-referenced-by-count":1,"title":["Gastrointestinal Symptoms in Autism Spectrum Disorder:\r A Case-Control Study"],"prefix":"10.7759","author":[{"given":"Khaled","family":"Alqoaer","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam O","family":"Alenzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Doha","family":"Abuharfel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aziza","family":"Alenazi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1176\/appi.books.9780890425596","article-title":"","year":"2013","unstructured":"Diagnostic and Statistical Manual of Mental Disorders. DSM-5. American Psychiatric Publishing, Inc., Washington, DC; 2013. 10.1176\/appi.books.9780890425596"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.2017.303696","article-title":"Injury mortality in individuals with autism","volume":"107","author":"Guan J","year":"2017","unstructured":"Guan J, Li G. Injury mortality in individuals with autism. Am J Public Health. 2017, 107:791-3. 10.2105\/AJPH.2017.303696","journal-title":"Am J Public Health"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3109\/1547691X.2010.545086","article-title":"Theoretical aspects of autism: causes--a review","volume":"8","author":"Ratajczak HV","year":"2011","unstructured":"Ratajczak HV. Theoretical aspects of autism: causes--a review. J Immunotoxicol. 2011, 8:68-79. 10.3109\/1547691X.2010.545086","journal-title":"J Immunotoxicol"},{"key":"ref4","article-title":"Evolution of the concept of autism [Article in French]","volume":"60","author":"Robel L","year":"2010","unstructured":"Robel L. Evolution of the concept of autism [Article in French]. Rev Prat. 2010, 60:376-8.","journal-title":"Rev Prat"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1017\/S003329171400172X","article-title":"The epidemiology and global burden of autism spectrum disorders","volume":"45","author":"Baxter AJ","year":"2015","unstructured":"Baxter AJ, Brugha TS, Erskine HE, Scheurer RW, Vos T, Scott JG. The epidemiology and global burden of autism spectrum disorders. Psychol Med. 2015, 45:601-13. 10.1017\/S003329171400172X","journal-title":"Psychol Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/jar.12238","article-title":"The prevalence of autism spectrum disorders in West Pomeranian and Pomeranian regions of Poland","volume":"30","author":"Skonieczna-\u017bydecka K","year":"2017","unstructured":"Skonieczna-\u017bydecka K, Gorzkowska I, Pierzak-Sominka J, Adler G. The prevalence of autism spectrum disorders in West Pomeranian and Pomeranian regions of Poland. J Appl Res Intellect Disabil. 2017, 30:283-9. 10.1111\/jar.12238","journal-title":"J Appl Res Intellect Disabil"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1002\/aur.2128","article-title":"Clustering of co-occurring conditions in autism spectrum disorder during early childhood: a retrospective analysis of medical claims data","volume":"12","author":"Vargason T","year":"2019","unstructured":"Vargason T, Frye RE, McGuinness DL, Hahn J. Clustering of co-occurring conditions in autism spectrum disorder during early childhood: a retrospective analysis of medical claims data. Autism Res. 2019, 12:1272-85. 10.1002\/aur.2128","journal-title":"Autism Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2009.07.018","article-title":"Clinical features in autism [Article in French]","volume":"16","author":"Robel L","year":"2009","unstructured":"Robel L. Clinical features in autism [Article in French]. Arch Pediatr. 2009, 16:1507-12. 10.1016\/j.arcped.2009.07.018","journal-title":"Arch Pediatr"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.nurt.2010.06.001","article-title":"Medical comorbidities in autism: challenges to diagnosis and treatment","volume":"7","author":"Bauman ML","year":"2010","unstructured":"Bauman ML. Medical comorbidities in autism: challenges to diagnosis and treatment. Neurotherapeutics. 2010, 7:320-7. 10.1016\/j.nurt.2010.06.001","journal-title":"Neurotherapeutics"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-011-1379-6","article-title":"Brief report: association between behavioral features and gastrointestinal problems among children with autism spectrum disorder","volume":"42","author":"Maenner MJ","year":"2012","unstructured":"Maenner MJ, Arneson CL, Levy SE, Kirby RS, Nicholas JS, Durkin MS. Brief report: association between behavioral features and gastrointestinal problems among children with autism spectrum disorder. J Autism Dev Disord. 2012, 42:1520-5. 10.1007\/s10803-011-1379-6","journal-title":"J Autism Dev Disord"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10802-012-9668-x","article-title":"Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders","volume":"41","author":"Mazurek MO","year":"2013","unstructured":"Mazurek MO, Vasa RA, Kalb LG, et al.. Anxiety, sensory over-responsivity, and gastrointestinal problems in children with autism spectrum disorders. J Abnorm Child Psychol. 2013, 41:165-76. 10.1007\/s10802-012-9668-x","journal-title":"J Abnorm Child Psychol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-017-3271-5","article-title":"Behavioral phenotype of ASD preschoolers with gastrointestinal symptoms or food selectivity","volume":"47","author":"Prosperi M","year":"2017","unstructured":"Prosperi M, Santocchi E, Balboni G, et al.. Behavioral phenotype of ASD preschoolers with gastrointestinal symptoms or food selectivity. J Autism Dev Disord. 2017, 47:3574-88. 10.1007\/s10803-017-3271-5","journal-title":"J Autism Dev Disord"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbi.2016.05.009","article-title":"Associations between cytokines, endocrine stress response, and gastrointestinal symptoms in autism spectrum disorder","volume":"58","author":"Ferguson BJ","year":"2016","unstructured":"Ferguson BJ, Marler S, Altstein LL, et al.. Associations between cytokines, endocrine stress response, and gastrointestinal symptoms in autism spectrum disorder. Brain Behav Immun. 2016, 58:57-62. 10.1016\/j.bbi.2016.05.009","journal-title":"Brain Behav Immun"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.15537\/smj.2021.42.4.20200630","article-title":"Prevalence and characteristics of autistic children attending autism centres in 2 major cities in Saudi Arabia: a cross-sectional study","volume":"42","author":"Sabbagh HJ","year":"2021","unstructured":"Sabbagh HJ, Al-Jabri BA, Alsulami MA, Hashem LA, Aljubour AA, Alamoudi RA. Prevalence and characteristics of autistic children attending autism centres in 2 major cities in Saudi Arabia: a cross-sectional study. Saudi Med J. 2021, 42:419-27. 10.15537\/smj.2021.42.4.20200630","journal-title":"Saudi Med J"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-3995","article-title":"Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis","volume":"133","author":"McElhanon BO","year":"2014","unstructured":"McElhanon BO, McCracken C, Karpen S, Sharp WG. Gastrointestinal symptoms in autism spectrum disorder: a meta-analysis. Pediatrics. 2014, 133:872-83. 10.1542\/peds.2013-3995","journal-title":"Pediatrics"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s10803-013-1973-x","article-title":"Gastrointestinal problems in children with autism, developmental delays or typical development","volume":"44","author":"Chaidez V","year":"2014","unstructured":"Chaidez V, Hansen RL, Hertz-Picciotto I. Gastrointestinal problems in children with autism, developmental delays or typical development. J Autism Dev Disord. 2014, 44:1117-27. 10.1007\/s10803-013-1973-x","journal-title":"J Autism Dev Disord"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3390\/medicina56010011","article-title":"A descriptive review on the prevalence of gastrointestinal disturbances and their multiple associations in autism spectrum disorder","volume":"56","author":"Lefter R","year":"2019","unstructured":"Lefter R, Ciobica A, Timofte D, Stanciu C, Trifan A. A descriptive review on the prevalence of gastrointestinal disturbances and their multiple associations in autism spectrum disorder. Medicina (Kaunas). 2019, 56:11. 10.3390\/medicina56010011","journal-title":"Medicina (Kaunas)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1080\/1028415X.2017.1388598","article-title":"Maternal breastfeeding and autism spectrum disorder in children: a systematic review and meta-analysis","volume":"22","author":"Tseng PT","year":"2019","unstructured":"Tseng PT, Chen YW, Stubbs B, et al.. Maternal breastfeeding and autism spectrum disorder in children: a systematic review and meta-analysis. Nutr Neurosci. 2019, 22:354-62. 10.1080\/1028415X.2017.1388598","journal-title":"Nutr Neurosci"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000907","article-title":"Breast milk protects against gastrointestinal symptoms in infants at high risk for autism during early development","volume":"62","author":"Penn AH","year":"2016","unstructured":"Penn AH, Carver LJ, Herbert CA, et al.. Breast milk protects against gastrointestinal symptoms in infants at high risk for autism during early development. J Pediatr Gastroenterol Nutr. 2016, 62:317-27. 10.1097\/MPG.0000000000000907","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/aur.2091","article-title":"Association between breastfeeding initiation and duration and autism spectrum disorder in preschool children enrolled in the study to explore early development","volume":"12","author":"Soke GN","year":"2019","unstructured":"Soke GN, Maenner M, Windham G, Moody E, Kaczaniuk J, DiGuiseppi C, Schieve LA. Association between breastfeeding initiation and duration and autism spectrum disorder in preschool children enrolled in the study to explore early development. Autism Res. 2019, 12:816-29. 10.1002\/aur.2091","journal-title":"Autism Res"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3390\/nu14010045","article-title":"Association of breastfeeding for the first six months of life and autism spectrum disorders: a national multi-center study in China","volume":"14","author":"Huang S","year":"2021","unstructured":"Huang S, Wang X, Sun T, et al.. Association of breastfeeding for the first six months of life and autism spectrum disorders: a national multi-center study in China. Nutrients. 2021, 14:45. 10.3390\/nu14010045","journal-title":"Nutrients"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-023-05022-z","article-title":"Feeding practice during infancy is associated with attention-deficit\/hyperactivity disorder and autism spectrum disorder: a population-based study in South Korea","volume":"182","author":"Cha JH","year":"2023","unstructured":"Cha JH, Cho Y, Moon JH, Lee J, Na JY, Kim YJ. Feeding practice during infancy is associated with attention-deficit\/hyperactivity disorder and autism spectrum disorder: a population-based study in South Korea. Eur J Pediatr. 2023, 182:3559-68. 10.1007\/s00431-023-05022-z","journal-title":"Eur J Pediatr"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-1878C","article-title":"Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report","volume":"125 Suppl 1","author":"Buie T","year":"2010","unstructured":"Buie T, Campbell DB, Fuchs GJ 3rd, et al.. Evaluation, diagnosis, and treatment of gastrointestinal disorders in individuals with ASDs: a consensus report. Pediatrics. 2010, 125 Suppl 1:S1-18. 10.1542\/peds.2009-1878C","journal-title":"Pediatrics"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1177\/1362361317733182","article-title":"The association between socioeconomic status and autism diagnosis in the United Kingdom for children aged 5-8\u2009years of age: findings from the Born in Bradford cohort","volume":"23","author":"Kelly B","year":"2019","unstructured":"Kelly B, Williams S, Collins S, et al.. The association between socioeconomic status and autism diagnosis in the United Kingdom for children aged 5-8\u2009years of age: findings from the Born in Bradford cohort. Autism. 2019, 23:131-40. 10.1177\/1362361317733182","journal-title":"Autism"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/281118-gastrointestinal-symptoms-in-autism-spectrum-disorder--a-case-control-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,31]],"date-time":"2024-08-31T12:34:39Z","timestamp":1725107679000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/281118-gastrointestinal-symptoms-in-autism-spectrum-disorder--a-case-control-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,31]]},"references-count":24,"URL":"https:\/\/doi.org\/10.7759\/cureus.68292","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8,31]]}}}