{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,12]],"date-time":"2026-06-12T16:29:27Z","timestamp":1781281767038,"version":"3.54.1"},"reference-count":21,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,3]]},"DOI":"10.7759\/cureus.68541","type":"journal-article","created":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T16:09:48Z","timestamp":1725379788000},"source":"Crossref","is-referenced-by-count":2,"title":["Clinical Profile and Outcomes of Patients With Systemic Lupus Erythematosus"],"prefix":"10.7759","author":[{"given":"Prasad  C","family":"Bagare","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Akshata","family":"Borle","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Priya","family":"Baluni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gayatri Gajanan","family":"Ekbote","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shashikala","family":"Sangale","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2009.11.018","article-title":"Defining and analyzing geoepidemiology and human autoimmunity","volume":"34","author":"Shapira Y","year":"2010","unstructured":"Shapira Y, Agmon-Levin N, Shoenfeld Y. Defining and analyzing geoepidemiology and human autoimmunity. J Autoimmun. 2010, 34:J168-77. 10.1016\/j.jaut.2009.11.018","journal-title":"J Autoimmun"},{"key":"ref2","article-title":"Epidemiology of systemic lupus erythematosus","author":"Duarte C","year":"2011","unstructured":"Duarte C, Couto M, Ines L, Liang MH. Epidemiology of systemic lupus erythematosus. Systemic Lupus Erythematosus. Lahita RG, Tsokos G, Buyon J, Koike T (ed): Elsevier, London; 2011. 673-96."},{"key":"ref3","article-title":"Prognostic factors in lupus nephritis: diagnostic and therapeutic delay increases the risk of terminal renal failure","volume":"33","author":"Faurschou M","year":"2006","unstructured":"Faurschou M, Starklint H, Halberg P, Jacobsen S. Prognostic factors in lupus nephritis: diagnostic and therapeutic delay increases the risk of terminal renal failure. J Rheumatol. 2006, 33:1563-9.","journal-title":"J Rheumatol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780251101","article-title":"The 1982 revised criteria for the classification of systemic lupus erythematosus","volume":"25","author":"Tan EM","year":"1982","unstructured":"Tan EM, Cohen AS, Fries JF, et al.. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982, 25:1271-7. 10.1002\/art.1780251101","journal-title":"Arthritis Rheum"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780400928","article-title":"Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus","volume":"40","author":"Hochberg MC","year":"1997","unstructured":"Hochberg MC. Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1997, 40:1725. 10.1002\/art.1780400928","journal-title":"Arthritis Rheum"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780350606","article-title":"Derivation of the SLEDAI. A disease activity index for lupus patients. The committee on prognosis studies in SLE","volume":"35","author":"Bombardier C","year":"1992","unstructured":"Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH. Derivation of the SLEDAI. A disease activity index for lupus patients. The committee on prognosis studies in SLE. Arthritis Rheum. 1992, 35:630-40. 10.1002\/art.1780350606","journal-title":"Arthritis Rheum"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.66487","article-title":"A cross-sectional hospital-based study of autoantibody profile and clinical manifestations of systemic lupus erythematosus in south Indian patients","volume":"28","author":"Kosaraju K","year":"2010","unstructured":"Kosaraju K, Shenoy S, Suchithra U. A cross-sectional hospital-based study of autoantibody profile and clinical manifestations of systemic lupus erythematosus in south Indian patients. Indian J Med Microbiol. 2010, 28:245-7. 10.4103\/0255-0857.66487","journal-title":"Indian J Med Microbiol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/0972-6691.116614","article-title":"A cross-sectional hospital based study of clinical and immunological profile of systemic lupus erythematosus patients from central rural India","volume":"27","author":"Agrawal S","year":"2013","unstructured":"Agrawal S, Jain A, Rajput A, Tiewsoh I. A cross-sectional hospital based study of clinical and immunological profile of systemic lupus erythematosus patients from central rural India. Indian Journal of Allergy, Asthma and Immunology. 2013, 27:33-7. 10.4103\/0972-6691.116614","journal-title":"Indian Journal of Allergy, Asthma and Immunology"},{"key":"ref9","doi-asserted-by":"crossref","DOI":"10.22631\/rr.2017.69997.1011","article-title":"Autoantibody profile, disease activity and organ involvement in iranian systemic lupus erythematosus patients","volume":"2","author":"Mahmoudi M","year":"2017","unstructured":"Mahmoudi M, Rastin M, Sahebari M, Zamani S, Tabasi N. Autoantibody profile, disease activity and organ involvement in iranian systemic lupus erythematosus patients. Rheum Res. 2017, 2:11-16.","journal-title":"Rheum Res"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2014-206334","article-title":"The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012","volume":"75","author":"Rees F","year":"2016","unstructured":"Rees F, Doherty M, Grainge M, Davenport G, Lanyon P, Zhang W. The incidence and prevalence of systemic lupus erythematosus in the UK, 1999-2012. Ann Rheum Dis. 2016, 75:136-41. 10.1136\/annrheumdis-2014-206334","journal-title":"Ann Rheum Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1177\/0961203309350755","article-title":"Review: Male systemic lupus erythematosus: a review of sex disparities in this disease","volume":"19","author":"Lu LJ","year":"2010","unstructured":"Lu LJ, Wallace DJ, Ishimori ML, Scofield RH, Weisman MH. Review: Male systemic lupus erythematosus: a review of sex disparities in this disease. Lupus. 2010, 19:119-29. 10.1177\/0961203309350755","journal-title":"Lupus"},{"key":"ref12","article-title":"Systemic lupus erythematosus in northern India: a review of 329 cases","volume":"36","author":"Malaviya AN","year":"1988","unstructured":"Malaviya AN, Singh RR, Kumar A, De A, Kumar A, Aradhye S. Systemic lupus erythematosus in northern India: a review of 329 cases. J Assoc Physicians India. 1988, 36:476-80, 484.","journal-title":"J Assoc Physicians India"},{"key":"ref13","article-title":"Clinical profile of systemic lupus erythematosus in North Kerala","volume":"11","author":"Binoy JP","year":"2003","unstructured":"Binoy JP, Mohammed F, Kumar N, Razia MV. Clinical profile of systemic lupus erythematosus in North Kerala. J Indian Rheumatol Assoc. 2003, 11:94-7.","journal-title":"J Indian Rheumatol Assoc"},{"key":"ref14","article-title":"Clinical profile of systemic lupus erythematosus at a tertiary care center in Western India","volume":"13","author":"Saigal R","year":"2011","unstructured":"Saigal R, Kansal A, Mittal M, Singh Y, Maharia HR, Juneja M. Clinical profile of systemic lupus erythematosus at a tertiary care center in Western India. Journal, Indian Academy of Clinical Medicine. 2011, 13:27-32.","journal-title":"Journal, Indian Academy of Clinical Medicine"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/0049-0172(80)90016-5","article-title":"The gastrointestinal manifestations of systemic lupus erythematosus: a review of the literature","volume":"9","author":"Hoffman BI","year":"1980","unstructured":"Hoffman BI, Katz WA. The gastrointestinal manifestations of systemic lupus erythematosus: a review of the literature. Semin Arthritis Rheum. 1980, 9:237-47. 10.1016\/0049-0172(80)90016-5","journal-title":"Semin Arthritis Rheum"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/art.1780371118","article-title":"Nucleosome-restricted antibodies are detected before anti-dsDNA and\/or antihistone antibodies in serum of MRL-Mp lpr\/lpr and +\/+ mice, and are present in kidney eluates of lupus mice with proteinuria","volume":"37","author":"Amoura Z","year":"1994","unstructured":"Amoura Z, Chabre H, Koutouzov S, Lotton C, Cabrespines A, Bach JF, Jacob L. Nucleosome-restricted antibodies are detected before anti-dsDNA and\/or antihistone antibodies in serum of MRL-Mp lpr\/lpr and +\/+ mice, and are present in kidney eluates of lupus mice with proteinuria. Arthritis Rheum. 1994, 37:1684-8. 10.1002\/art.1780371118","journal-title":"Arthritis Rheum"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.5.431","article-title":"Anti-chromatin antibodies in systemic lupus erythematosus: a useful marker for lupus nephropathy","volume":"62","author":"Cervera R","year":"2003","unstructured":"Cervera R, Vi\u00f1as O, Ramos-Casals M, et al.. Anti-chromatin antibodies in systemic lupus erythematosus: a useful marker for lupus nephropathy. Ann Rheum Dis. 2003, 62:431-4. 10.1136\/ard.62.5.431","journal-title":"Ann Rheum Dis"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-012-9825-6","article-title":"Simultaneous positivity for anti-DNA, anti-nucleosome and anti-histone antibodies is a marker for more severe lupus nephritis","volume":"33","author":"Sui M","year":"2013","unstructured":"Sui M, Lin Q, Xu Z, et al.. Simultaneous positivity for anti-DNA, anti-nucleosome and anti-histone antibodies is a marker for more severe lupus nephritis. J Clin Immunol. 2013, 33:378-87. 10.1007\/s10875-012-9825-6","journal-title":"J Clin Immunol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/ard.62.6.556","article-title":"Anti-dsDNA, anti-Sm antibodies, and the lupus anticoagulant: significant factors associated with lupus nephritis","volume":"62","author":"Alba P","year":"2003","unstructured":"Alba P, Bento L, Cuadrado MJ, et al.. Anti-dsDNA, anti-Sm antibodies, and the lupus anticoagulant: significant factors associated with lupus nephritis. Ann Rheum Dis. 2003, 62:556-60. 10.1136\/ard.62.6.556","journal-title":"Ann Rheum Dis"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2003.08.034","article-title":"Antihistone and anti-double-stranded deoxyribonucleic acid antibodies are associated with renal disease in systemic lupus erythematosus","volume":"116","author":"Cort\u00e9s-Hern\u00e1ndez J","year":"2004","unstructured":"Cort\u00e9s-Hern\u00e1ndez J, Ordi-Ros J, Labrador M, Buj\u00e1n S, Balada E, Segarra A, Vilardell-Tarr\u00e9s M. Antihistone and anti-double-stranded deoxyribonucleic acid antibodies are associated with renal disease in systemic lupus erythematosus. Am J Med. 2004, 116:165-73. 10.1016\/j.amjmed.2003.08.034","journal-title":"Am J Med"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0b013e3181cb449c","article-title":"Clinical and serologic correlations and autoantibody clusters in systemic lupus erythematosus: a retrospective review of 917 patients in South China","volume":"89","author":"Tang X","year":"2010","unstructured":"Tang X, Huang Y, Deng W, Tang L, Weng W, Zhang X. Clinical and serologic correlations and autoantibody clusters in systemic lupus erythematosus: a retrospective review of 917 patients in South China. Medicine (Baltimore). 2010, 89:62-7. 10.1097\/MD.0b013e3181cb449c","journal-title":"Medicine (Baltimore)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/282612-clinical-profile-and-outcomes-of-patients-with-systemic-lupus-erythematosus","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,3]],"date-time":"2024-09-03T16:09:51Z","timestamp":1725379791000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/282612-clinical-profile-and-outcomes-of-patients-with-systemic-lupus-erythematosus"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,3]]},"references-count":21,"URL":"https:\/\/doi.org\/10.7759\/cureus.68541","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,3]]}}}