{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T17:40:15Z","timestamp":1770226815676,"version":"3.49.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,9,26]]},"DOI":"10.7759\/cureus.70241","type":"journal-article","created":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T10:16:01Z","timestamp":1727345761000},"source":"Crossref","is-referenced-by-count":2,"title":["Recurrent Intrathoracic Liposarcoma: A Case Report and a Comprehensive Literature Review of a Rare Clinical Entity"],"prefix":"10.7759","author":[{"given":"Vasileios","family":"Leivaditis","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manfred","family":"Dahm","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Athanasios","family":"Papatriantafyllou","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Georg","family":"Keul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lydia","family":"Kohl","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Joachim","family":"Sch\u00e4fers","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-009-0815-x","article-title":"Well-differentiated and dedifferentiated liposarcomas","volume":"456","author":"Coindre JM","year":"2010","unstructured":"Coindre JM, P\u00e9deutour F, Aurias A. Well-differentiated and dedifferentiated liposarcomas. Virchows Arch. 2010, 456:167-79. 10.1007\/s00428-009-0815-x","journal-title":"Virchows Arch"},{"key":"ref2","article-title":"Thoracic liposarcoma in an end stage renal disease patient","volume":"31","author":"Ishtiaq R","year":"2019","unstructured":"Ishtiaq R, Naeem A, Ratnani I. Thoracic liposarcoma in an end stage renal disease patient. J Ayub Med Coll Abbottabad. 2019, 31:286-9.","journal-title":"J Ayub Med Coll Abbottabad"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11247353","article-title":"Clinicopathological features of intrathoracic liposarcoma-a systematic review with an illustrative case","volume":"11","author":"Kie\u0142bowski K","year":"2022","unstructured":"Kie\u0142bowski K, Ruszel N, Skrzyniarz SA, et al.. Clinicopathological features of intrathoracic liposarcoma-a systematic review with an illustrative case. J Clin Med. 2022, 11:7353. 10.3390\/jcm11247353","journal-title":"J Clin Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2023.03.009","article-title":"Liposarcoma of the pleural cavity","volume":"136","author":"Kawai T","year":"2023","unstructured":"Kawai T, Nakashima H, Washimi K, et al.. Liposarcoma of the pleural cavity. Hum Pathol. 2023, 136:105-13. 10.1016\/j.humpath.2023.03.009","journal-title":"Hum Pathol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000135524.73447.4a","article-title":"Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases","volume":"28","author":"Hornick JL","year":"2004","unstructured":"Hornick JL, Bosenberg MW, Mentzel T, McMenamin ME, Oliveira AM, Fletcher CD. Pleomorphic liposarcoma: clinicopathologic analysis of 57 cases. Am J Surg Pathol. 2004, 28:1257-67. 10.1097\/01.pas.0000135524.73447.4a","journal-title":"Am J Surg Pathol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.26513","article-title":"Mediastinal liposarcoma with anterior and posterior mediastinal involvement: a thoracic oncovascular case report","volume":"14","author":"Keita P","year":"2022","unstructured":"Keita P, Tran A, Cheema M, Peterman NJ, Katigbak M. Mediastinal liposarcoma with anterior and posterior mediastinal involvement: a thoracic oncovascular case report. Cureus. 2022, 14:e26513. 10.7759\/cureus.26513","journal-title":"Cureus"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2018.1757","article-title":"Pleural dedifferentiated liposarcoma: a case report","volume":"10","author":"Matsukuma S","year":"2019","unstructured":"Matsukuma S, Oshika Y, Utsumi Y, Obara K, Tanimoto T, Katsurada Y, Takeo H. Pleural dedifferentiated liposarcoma: a case report. Mol Clin Oncol. 2019, 10:132-6. 10.3892\/mco.2018.1757","journal-title":"Mol Clin Oncol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1177\/2050313X231206031","article-title":"Giant primary liposarcoma of the mediastinum: a case report and review of the literature","volume":"11","author":"Rao J","year":"2023","unstructured":"Rao J, Zhu Q, Yang X. Giant primary liposarcoma of the mediastinum: a case report and review of the literature. SAGE Open Med Case Rep. 2023, 11:2050313X231206031. 10.1177\/2050313X231206031","journal-title":"SAGE Open Med Case Rep"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3978\/j.issn.2072-1439.2014.07.30","article-title":"Primary pleural liposarcoma, pleomorphic variant","volume":"6","author":"Carrillo B JA","year":"2014","unstructured":"Carrillo B JA, Navarrete C, L\u00f3pez Arias MA, Pel\u00e1ez M. Primary pleural liposarcoma, pleomorphic variant. J Thorac Dis. 2014, 6:E166-8. 10.3978\/j.issn.2072-1439.2014.07.30","journal-title":"J Thorac Dis"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/1759-7714.12888","article-title":"Primary mediastinal dedifferentiated liposarcoma: five case reports and a review","volume":"9","author":"Miura K","year":"2018","unstructured":"Miura K, Hamanaka K, Matsuoka S, et al.. Primary mediastinal dedifferentiated liposarcoma: five case reports and a review. Thorac Cancer. 2018, 9:1733-40. 10.1111\/1759-7714.12888","journal-title":"Thorac Cancer"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13019-019-0965-0","article-title":"Resection of a huge mediastinal well-differentiated liposarcoma involving left thoracic cavity","volume":"14","author":"Zhang M","year":"2019","unstructured":"Zhang M, Zhang S, Shi H, Li W, Wei Z. Resection of a huge mediastinal well-differentiated liposarcoma involving left thoracic cavity. J Cardiothorac Surg. 2019, 14:148. 10.1186\/s13019-019-0965-0","journal-title":"J Cardiothorac Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5858\/2008-132-1149-PPNEOT","article-title":"Primary pleural neoplasia: entities other than diffuse malignant mesothelioma","volume":"132","author":"Guinee DG","year":"2008","unstructured":"Guinee DG, Allen TC. Primary pleural neoplasia: entities other than diffuse malignant mesothelioma. Arch Pathol Lab Med. 2008, 132:1149-70. 10.5858\/2008-132-1149-PPNEOT","journal-title":"Arch Pathol Lab Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-023-04121-7","article-title":"Mediastinal liposarcoma: a case report and review of the literature","volume":"17","author":"Ataya J","year":"2023","unstructured":"Ataya J, Nahle AA, Hamdar H, Sikaria A, Souleiman Y. Mediastinal liposarcoma: a case report and review of the literature. J Med Case Rep. 2023, 17:372. 10.1186\/s13256-023-04121-7","journal-title":"J Med Case Rep"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1097\/PAT.0000000000000048","article-title":"Grading of soft tissue sarcomas: from histological to molecular assessment","volume":"46","author":"Neuville A","year":"2014","unstructured":"Neuville A, Chibon F, Coindre JM. Grading of soft tissue sarcomas: from histological to molecular assessment. Pathology. 2014, 46:113-20. 10.1097\/PAT.0000000000000048","journal-title":"Pathology"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtho.2021.12.014","article-title":"The 2021 WHO Classification of Tumors of the Pleura: advances since the 2015 classification","volume":"17","author":"Sauter JL","year":"2022","unstructured":"Sauter JL, Dacic S, Galateau-Salle F, et al.. The 2021 WHO Classification of Tumors of the Pleura: advances since the 2015 classification. J Thorac Oncol. 2022, 17:608-22. 10.1016\/j.jtho.2021.12.014","journal-title":"J Thorac Oncol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2015.04.004","article-title":"Imaging features of primary and recurrent intrathoracic synovial sarcoma: a single-institute experience","volume":"39","author":"Baheti AD","year":"2015","unstructured":"Baheti AD, Sewatkar R, Hornick JL, Saboo SS, Jagannathan JP, Ramaiya NH, Tirumani SH. Imaging features of primary and recurrent intrathoracic synovial sarcoma: a single-institute experience. Clin Imaging. 2015, 39:803-8. 10.1016\/j.clinimag.2015.04.004","journal-title":"Clin Imaging"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/7594027","article-title":"Diagnosis and prognosis of retroperitoneal liposarcoma: a single Asian center cohort of 57 cases","volume":"2021","author":"Xiao J","year":"2021","unstructured":"Xiao J, Liu J, Chen M, Liu W, He X. Diagnosis and prognosis of retroperitoneal liposarcoma: a single Asian center cohort of 57 cases. J Oncol. 2021, 2021:7594027. 10.1155\/2021\/7594027","journal-title":"J Oncol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s11748-014-0510-y","article-title":"Successful resection of recurrent mediastinal liposarcoma using preoperative evaluation of organ invasion by four-dimensional computed tomography","volume":"64","author":"Fujimoto R","year":"2016","unstructured":"Fujimoto R, Sato M, Miyata R, Minakata K, Omasa M, Kubo T, Date H. Successful resection of recurrent mediastinal liposarcoma using preoperative evaluation of organ invasion by four-dimensional computed tomography. Gen Thorac Cardiovasc Surg. 2016, 64:488-91. 10.1007\/s11748-014-0510-y","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.23774","article-title":"The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution","volume":"113","author":"Mussi C","year":"2008","unstructured":"Mussi C, Collini P, Miceli R, et al.. The prognostic impact of dedifferentiation in retroperitoneal liposarcoma: a series of surgically treated patients at a single institution. Cancer. 2008, 113:1657-65. 10.1002\/cncr.23774","journal-title":"Cancer"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000234795.98607.00","article-title":"Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk","volume":"244","author":"Dalal KM","year":"2006","unstructured":"Dalal KM, Kattan MW, Antonescu CR, Brennan MF, Singer S. Subtype specific prognostic nomogram for patients with primary liposarcoma of the retroperitoneum, extremity, or trunk. Ann Surg. 2006, 244:381-91. 10.1097\/01.sla.0000234795.98607.00","journal-title":"Ann Surg"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-197912000-00004","article-title":"Liposarcoma: a study of 55 cases with a reassessment of its classification","volume":"3","author":"Evans HL","year":"1979","unstructured":"Evans HL. Liposarcoma: a study of 55 cases with a reassessment of its classification. Am J Surg Pathol. 1979, 3:507-23. 10.1097\/00000478-197912000-00004","journal-title":"Am J Surg Pathol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-023-01064-5","article-title":"Myxoid liposarcoma: how to stage and follow","volume":"24","author":"Ho TP","year":"2023","unstructured":"Ho TP. Myxoid liposarcoma: how to stage and follow. Curr Treat Options Oncol. 2023, 24:292-9. 10.1007\/s11864-023-01064-5","journal-title":"Curr Treat Options Oncol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2016.05.007","article-title":"Liposarcoma: multimodality management and future targeted therapies","volume":"25","author":"Crago AM","year":"2016","unstructured":"Crago AM, Dickson MA. Liposarcoma: multimodality management and future targeted therapies. Surg Oncol Clin N Am. 2016, 25:761-73. 10.1016\/j.soc.2016.05.007","journal-title":"Surg Oncol Clin N Am"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3857\/roj.2016.01858","article-title":"Retroperitoneal liposarcoma: the role of adjuvant radiation therapy and the prognostic factors","volume":"34","author":"Lee HS","year":"2016","unstructured":"Lee HS, Yu JI, Lim DH, Kim SJ. Retroperitoneal liposarcoma: the role of adjuvant radiation therapy and the prognostic factors. Radiat Oncol J. 2016, 34:216-22. 10.3857\/roj.2016.01858","journal-title":"Radiat Oncol J"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(20)30446-0","article-title":"Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC- 62092: STRASS): a multicentre, open-label, randomised, phase 3 trial","volume":"21","author":"onvalot S","year":"2020","unstructured":"onvalot S, Gronchi A, Le P\u00e9choux C, et al.. Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC- 62092: STRASS): a multicentre, open-label, randomised, phase 3 trial. Lancet Oncol. 2020, 21:1366-77. 10.1016\/S1470-2045(20)30446-0","journal-title":"Lancet Oncol"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1080\/17512433.2017.1289086","article-title":"Pharmacological therapies for liposarcoma","volume":"10","author":"Saponara M","year":"2017","unstructured":"Saponara M, Stacchiotti S, Gronchi A. Pharmacological therapies for liposarcoma. Expert Rev Clin Pharmacol. 2017, 10:361-77. 10.1080\/17512433.2017.1289086","journal-title":"Expert Rev Clin Pharmacol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2021.496","article-title":"Clinicopathologic characteristics and clinical outcome of localized liposarcoma: a single-center experience over 25 years and evaluation of PD-L1 expression","volume":"54","author":"Chae H","year":"2022","unstructured":"Chae H, Kim JE, Kim W, et al.. Clinicopathologic characteristics and clinical outcome of localized liposarcoma: a single-center experience over 25 years and evaluation of PD-L1 expression. Cancer Res Treat. 2022, 54:579-89. 10.4143\/crt.2021.496","journal-title":"Cancer Res Treat"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/299786-recurrent-intrathoracic-liposarcoma-a-case-report-and-a-comprehensive-literature-review-of-a-rare-clinical-entity","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,9,26]],"date-time":"2024-09-26T10:16:05Z","timestamp":1727345765000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/299786-recurrent-intrathoracic-liposarcoma-a-case-report-and-a-comprehensive-literature-review-of-a-rare-clinical-entity"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,26]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.70241","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,9,26]]}}}