{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,22]],"date-time":"2026-10-22T13:27:25Z","timestamp":1792675645897,"version":"4.5.0"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,10,13]]},"DOI":"10.7759\/cureus.71363","type":"journal-article","created":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T15:21:36Z","timestamp":1728832896000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparing the Postoperative Analgesic Efficacy of Ketorolac and Tramadol After Open Inguinal Hernia Mesh Repair: A Randomized Controlled Trial"],"prefix":"10.7759","author":[{"given":"Syed M","family":"Ahmed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sidra","family":"Shabbir","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nauman A","family":"Rana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atia","family":"Khatoon","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Umar F","family":"Ghani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Irmaghana","family":"Basharat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad  N","family":"Khan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fahd M","family":"Hameed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad F","family":"Dar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Inguinal hernia","author":"Hammoud M","year":"2023","unstructured":"Hammoud M, Gerken J. Inguinal hernia. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2023."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3182a19725","article-title":"Long-term results of a randomized controlled trial of a nonoperative strategy (watchful waiting) for men with minimally symptomatic inguinal hernias","volume":"258","author":"Fitzgibbons RJ Jr","year":"2013","unstructured":"Fitzgibbons RJ Jr, Ramanan B, Arya S, Turner SA, Li X, Gibbs JO, Reda DJ. Long-term results of a randomized controlled trial of a nonoperative strategy (watchful waiting) for men with minimally symptomatic inguinal hernias. Ann Surg. 2013, 258:508-15. 10.1097\/SLA.0b013e3182a19725","journal-title":"Ann Surg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.20517\/2574-1225.2021.26","article-title":"Comparison of open and laparoscopic inguinal hernia repair","volume":"5","author":"Burton V","year":"2021","unstructured":"Burton V, Perez AJ. Comparison of open and laparoscopic inguinal hernia repair. Mini-invasive Surgery. 2021, 5:26. 10.20517\/2574-1225.2021.26","journal-title":"Mini-invasive Surgery"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.5455\/medarh.2020.74.355-358","article-title":"Postoperative pain scores after open inguinal hernia repair: comparison of three postoperative analgesic regimens","volume":"74","author":"Mulita F","year":"2020","unstructured":"Mulita F, Parchas N, Solou K, Tchabashvili L, Gatomati F, Iliopoulos F, Maroulis I. Postoperative pain scores after open inguinal hernia repair: comparison of three postoperative analgesic regimens. Med Arch. 2020, 74:355-8. 10.5455\/medarh.2020.74.355-358","journal-title":"Med Arch"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(99)03313-9","article-title":"Acute pain","volume":"353","author":"Carr DB","year":"1999","unstructured":"Carr DB, Goudas LC. Acute pain. Lancet. 1999, 353:2051-8. 10.1016\/S0140-6736(99)03313-9","journal-title":"Lancet"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/87.1.62","article-title":"Effect of postoperative analgesia on surgical outcome","volume":"87","author":"Kehlet H","year":"2001","unstructured":"Kehlet H, Holte K. Effect of postoperative analgesia on surgical outcome. Br J Anaesth. 2001, 87:62-72. 10.1093\/bja\/87.1.62","journal-title":"Br J Anaesth"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1351138","article-title":"Postoperative pain control","volume":"26","author":"Garimella V","year":"2013","unstructured":"Garimella V, Cellini C. Postoperative pain control. Clin Colon Rectal Surg. 2013, 26:191-6. 10.1055\/s-0033-1351138","journal-title":"Clin Colon Rectal Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1Q041","article-title":"Influence of intravenous opioid dose on postoperative ileus","volume":"45","author":"Barletta JF","year":"2011","unstructured":"Barletta JF, Asgeirsson T, Senagore AJ. Influence of intravenous opioid dose on postoperative ileus. Ann Pharmacother. 2011, 45:916-23. 10.1345\/aph.1Q041","journal-title":"Ann Pharmacother"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/pds.1338","article-title":"In-hospital use of opioids increases rate of coded postoperative paralytic ileus","volume":"16","author":"Goettsch WG","year":"2007","unstructured":"Goettsch WG, Sukel MP, van der Peet DL, van Riemsdijk MM, Herings RM. In-hospital use of opioids increases rate of coded postoperative paralytic ileus. Pharmacoepidemiol Drug Saf. 2007, 16:668-74. 10.1002\/pds.1338","journal-title":"Pharmacoepidemiol Drug Saf"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.17226\/24781","article-title":"Pain Management and the Opioid Epidemic: Balancing Societal and Individual Benefits and Risks of Prescription Opioid Use","year":"2017","unstructured":"Pain Management and the Opioid Epidemic. Balancing Societal and Individual Benefits and Risks of Prescription Opioid Use. Phillips JK, Ford MA, Bonnie RJ (ed): National Academies Press (US), Washington (DC); 2017. 10.17226\/24781"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-6576.2005.00674.x","article-title":"Effect of adding ketorolac to intravenous morphine patient-controlled analgesia on bowel function in colorectal surgery patients--a prospective, randomized, double-blind study","volume":"49","author":"Chen JY","year":"2005","unstructured":"Chen JY, Wu GJ, Mok MS, et al.. Effect of adding ketorolac to intravenous morphine patient-controlled analgesia on bowel function in colorectal surgery patients--a prospective, randomized, double-blind study. Acta Anaesthesiol Scand. 2005, 49:546-51. 10.1111\/j.1399-6576.2005.00674.x","journal-title":"Acta Anaesthesiol Scand"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00000539-200104000-00038","article-title":"The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery","volume":"92","author":"Pavy TJ","year":"2001","unstructured":"Pavy TJ, Paech MJ, Evans SF. The effect of intravenous ketorolac on opioid requirement and pain after cesarean delivery. Anesth Analg. 2001, 92:1010-4. 10.1097\/00000539-200104000-00038","journal-title":"Anesth Analg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1213\/ANE.0b013e3182334d68","article-title":"Perioperative single dose ketorolac to prevent postoperative pain: a meta-analysis of randomized trials","volume":"114","author":"De Oliveira GS Jr","year":"2012","unstructured":"De Oliveira GS Jr, Agarwal D, Benzon HT. Perioperative single dose ketorolac to prevent postoperative pain: a meta-analysis of randomized trials. Anesth Analg. 2012, 114:424-33. 10.1213\/ANE.0b013e3182334d68","journal-title":"Anesth Analg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.5455\/2319-2003.ijbcp20130814","article-title":"Comparison of postoperative analgesic efficacy and safety of parecoxib and ketorolac in patients of inguinal hernia","volume":"2","author":"Zende AM","year":"2013","unstructured":"Zende AM, Bhosale RR. Comparison of postoperative analgesic efficacy and safety of parecoxib and ketorolac in patients of inguinal hernia. Int J Basic Clin Pharmacol. 2013, 2:414-20. 10.5455\/2319-2003.ijbcp20130814","journal-title":"Int J Basic Clin Pharmacol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jclinane.2015.06.008","article-title":"Effect of postoperative analgesia on acute and persistent postherniotomy pain: a randomized study","volume":"27","author":"Bugada D","year":"2015","unstructured":"Bugada D, Lavand'homme P, Ambrosoli AL, et al.. Effect of postoperative analgesia on acute and persistent postherniotomy pain: a randomized study. J Clin Anesth. 2015, 27:658-64. 10.1016\/j.jclinane.2015.06.008","journal-title":"J Clin Anesth"},{"key":"ref16","article-title":"Pain management after open inguinal hernia repair: an updated systematic review and procedure-specific postoperative pain management (PROSPECT\/ESRA) recommendations","volume":"71","author":"Coppens S","year":"2020","unstructured":"Coppens S, Gidts L, Huynen P, de Velde V, Joshi GP. Pain management after open inguinal hernia repair: an updated systematic review and procedure-specific postoperative pain management (PROSPECT\/ESRA) recommendations. Acta Anaesthesiologica Belgica. 2020, 71:45-56.","journal-title":"Acta Anaesthesiologica Belgica"},{"key":"ref17","article-title":"Comparison of diclofenac sodium and morphine sulphate for postoperative analgesia after day case inguinal hernia surgery","volume":"78","author":"McEvoy A","year":"1996","unstructured":"McEvoy A, Livingstone JI, Cahill CJ. Comparison of diclofenac sodium and morphine sulphate for postoperative analgesia after day case inguinal hernia surgery. Ann R Coll Surg Engl. 1996, 78:363-6.","journal-title":"Ann R Coll Surg Engl"},{"key":"ref18","article-title":"Postoperative ileus","author":"Buchanan L","year":"2023","unstructured":"Buchanan L, Tuma F. Postoperative ileus. StatPearls [Internet]. StatPearls Publishing, Treasure Island (FL); 2023."},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.05.014","article-title":"Opioids in gastroenterology: treating adverse effects and creating therapeutic benefits","volume":"15","author":"Camilleri M","year":"2017","unstructured":"Camilleri M, Lembo A, Katzka DA. Opioids in gastroenterology: treating adverse effects and creating therapeutic benefits. Clin Gastroenterol Hepatol. 2017, 15:1338-49. 10.1016\/j.cgh.2017.05.014","journal-title":"Clin Gastroenterol Hepatol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.2174\/138161212803582469","article-title":"Non-analgesic effects of opioids: opioid-induced respiratory depression","volume":"18","author":"Boom M","year":"2012","unstructured":"Boom M, Niesters M, Sarton E, Aarts L, Smith TW, Dahan A. Non-analgesic effects of opioids: opioid-induced respiratory depression. Curr Pharm Des. 2012, 18:5994-6004. 10.2174\/138161212803582469","journal-title":"Curr Pharm Des"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3390\/ph17020205","article-title":"Risk factors for respiratory depression associated with tramadol based on the Global Pharmacovigilance Database (VigiBase)","volume":"17","author":"Park S","year":"2024","unstructured":"Park S, Lee GH, Kim S, Kim S, Kim Y, Choi SA. Risk factors for respiratory depression associated with tramadol based on the Global Pharmacovigilance Database (VigiBase). Pharmaceuticals (Basel). 2024, 17:205. 10.3390\/ph17020205","journal-title":"Pharmaceuticals (Basel)"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i18.2147","article-title":"Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility","volume":"18","author":"Takeuchi K","year":"2012","unstructured":"Takeuchi K. Pathogenesis of NSAID-induced gastric damage: importance of cyclooxygenase inhibition and gastric hypermotility. World J Gastroenterol. 2012, 18:2147-60. 10.3748\/wjg.v18.i18.2147","journal-title":"World J Gastroenterol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.7861\/clinmed.2021-0039","article-title":"Non-steroidal anti-inflammatory drugs and the gastrointestinal tract","volume":"21","author":"Tai FW","year":"2021","unstructured":"Tai FW, McAlindon ME. Non-steroidal anti-inflammatory drugs and the gastrointestinal tract. Clin Med (Lond). 2021, 21:131-4. 10.7861\/clinmed.2021-0039","journal-title":"Clin Med (Lond)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/308181-comparing-the-postoperative-analgesic-efficacy-of-ketorolac-and-tramadol-after-open-inguinal-hernia-mesh-repair-a-randomized-controlled-trial","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,10,13]],"date-time":"2024-10-13T15:21:38Z","timestamp":1728832898000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/308181-comparing-the-postoperative-analgesic-efficacy-of-ketorolac-and-tramadol-after-open-inguinal-hernia-mesh-repair-a-randomized-controlled-trial"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,10,13]]},"references-count":23,"URL":"https:\/\/doi.org\/10.7759\/cureus.71363","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,10,13]]}}}