{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T11:58:11Z","timestamp":1787313491749,"version":"build-2736575974"},"reference-count":34,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,20]]},"DOI":"10.7759\/cureus.74115","type":"journal-article","created":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T23:57:39Z","timestamp":1732147059000},"source":"Crossref","is-referenced-by-count":1,"title":["Obesity and Sympathetic Overactivity in Young Individuals With Hypertension: Clinical Perspective of Indian Healthcare Providers"],"prefix":"10.7759","author":[{"given":"Uday","family":"Jadhav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dharmesh","family":"Solanki","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srinivas","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Hazra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Alexander","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amit","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shweta","family":"Ghatge","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Santosh","family":"Revankar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"National Center for Health Statistics. Hypertension prevalence, awareness, treatment, and control among adults age 18 and older. United States, August 2021-August 2023. (2024). https:\/\/www.cdc.gov\/nchs\/products\/databriefs\/db511.htm."},{"key":"ref2","unstructured":"WHO. Hypertension. (2023). https.\/\/www.who.int\/news-room\/fact-sheets\/detail\/hypertension#:~:text=Approximately%201%20in%205%20adults,33%25%20bet...."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000000146","article-title":"Hypertension in India: a systematic review and meta-analysis of prevalence, awareness, and control of hypertension","volume":"32","author":"Anchala R","year":"2014","unstructured":"Anchala R, Kannuri NK, Pant H, Khan H, Franco OH, Di Angelantonio E, Prabhakaran D. Hypertension in India: a systematic review and meta-analysis of prevalence, awareness, and control of hypertension. J Hypertens. 2014, 32:1170-7. 10.1097\/HJH.0000000000000146","journal-title":"J Hypertens"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0191948","article-title":"Prevalence and correlates of hypertension in Maharashtra, India: a multilevel analysis","volume":"13","author":"Bhise MD","year":"2018","unstructured":"Bhise MD, Patra S. Prevalence and correlates of hypertension in Maharashtra, India: a multilevel analysis. PLoS One. 2018, 13:e0191948. 10.1371\/journal.pone.0191948","journal-title":"PLoS One"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2022.765442","article-title":"Prevalence, awareness, treatment, and control of hypertension in young adults (20-39 years) in Kerala, South India","volume":"9","author":"Geevar Z","year":"2022","unstructured":"Geevar Z, Krishnan MN, Venugopal K, et al.. Prevalence, awareness, treatment, and control of hypertension in young adults (20-39 years) in Kerala, South India. Front Cardiovasc Med. 2022, 9:765442. 10.3389\/fcvm.2022.765442","journal-title":"Front Cardiovasc Med"},{"key":"ref6","article-title":"Hypertension prevalence among adults aged 18 and over: United States, 2017-2018","author":"Ostchega Y","year":"2020","unstructured":"Ostchega Y, Fryar CD, Nwankwo T, Nguyen DT. Hypertension prevalence among adults aged 18 and over: United States, 2017-2018. NCHS Data Brief, No 364. National Center for Health Statistics, Hyattsville, MD; 2020."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.123.033053","article-title":"Association between young adult characteristics and blood pressure trajectories","volume":"13","author":"An J","year":"2024","unstructured":"An J, Fischer H, Ni L, et al.. Association between young adult characteristics and blood pressure trajectories. J Am Heart Assoc. 2024, 13:e033053. 10.1161\/JAHA.123.033053","journal-title":"J Am Heart Assoc"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2011.08.032","article-title":"Blood pressure matters, even during young adulthood","volume":"58","author":"Bibbins-Domingo K","year":"2011","unstructured":"Bibbins-Domingo K, Pletcher MJ. Blood pressure matters, even during young adulthood. J Am Coll Cardiol. 2011, 58:2404-5. 10.1016\/j.jacc.2011.08.032","journal-title":"J Am Coll Cardiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.dsx.2018.08.032","article-title":"Prevalence of obesity in India: a systematic review","volume":"13","author":"Ahirwar R","year":"2019","unstructured":"Ahirwar R, Mondal PR. Prevalence of obesity in India: a systematic review. Diabetes Metab Syndr. 2019, 13:318-21. 10.1016\/j.dsx.2018.08.032","journal-title":"Diabetes Metab Syndr"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.118.11676","article-title":"Obesity-associated organ damage and sympathetic nervous activity: a target for treatment?","volume":"73","author":"Lambert EA","year":"2019","unstructured":"Lambert EA, Esler MD, Schlaich MP, Dixon J, Eikelis N, Lambert GW. Obesity-associated organ damage and sympathetic nervous activity: a target for treatment?. Hypertension. 2019, 73:1150-9. 10.1161\/HYPERTENSIONAHA.118.11676","journal-title":"Hypertension"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2015.00234","article-title":"Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?","volume":"6","author":"Moreira MC","year":"2015","unstructured":"Moreira MC, Pinto IS, Mour\u00e3o AA, et al.. Does the sympathetic nervous system contribute to the pathophysiology of metabolic syndrome?. Front Physiol. 2015, 6:234. 10.3389\/fphys.2015.00234","journal-title":"Front Physiol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgab645","article-title":"Insulin resistance and cardiometabolic risk profile among nondiabetic American young adults: insights from NHANES","volume":"107","author":"Parcha V","year":"2022","unstructured":"Parcha V, Heindl B, Kalra R, Li P, Gower B, Arora G, Arora P. Insulin resistance and cardiometabolic risk profile among nondiabetic American young adults: insights from NHANES. J Clin Endocrinol Metab. 2022, 107:e25-37. 10.1210\/clinem\/dgab645","journal-title":"J Clin Endocrinol Metab"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-021-01356-w","article-title":"Autonomic nervous system activity changes in patients with hypertension and overweight: role and therapeutic implications","volume":"20","author":"Valensi P","year":"2021","unstructured":"Valensi P. Autonomic nervous system activity changes in patients with hypertension and overweight: role and therapeutic implications. Cardiovasc Diabetol. 2021, 20:170. 10.1186\/s12933-021-01356-w","journal-title":"Cardiovasc Diabetol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-018-0762-4","article-title":"Association between insulin resistance and the development of cardiovascular disease","volume":"17","author":"Ormazabal V","year":"2018","unstructured":"Ormazabal V, Nair S, Elfeky O, Aguayo C, Salomon C, Zu\u00f1iga FA. Association between insulin resistance and the development of cardiovascular disease. Cardiovasc Diabetol. 2018, 17:122. 10.1186\/s12933-018-0762-4","journal-title":"Cardiovasc Diabetol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.05.020","article-title":"Hypertension in the young: preventing the evolution of disease versus prevention of clinical events","volume":"50","author":"Williams B","year":"2007","unstructured":"Williams B. Hypertension in the young: preventing the evolution of disease versus prevention of clinical events. J Am Coll Cardiol. 2007, 50:840-2. 10.1016\/j.jacc.2007.05.020","journal-title":"J Am Coll Cardiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehy339","article-title":"2018 ESC\/ESH guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH)","volume":"39","author":"Williams B","year":"2018","unstructured":"Williams B, Mancia G, Spiering W, et al.. 2018 ESC\/ESH guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH). Eur Heart J. 2018, 39:3021-104. 10.1093\/eurheartj\/ehy339","journal-title":"Eur Heart J"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.15026","article-title":"2020 International Society of Hypertension global hypertension practice guidelines","volume":"75","author":"Unger T","year":"2020","unstructured":"Unger T, Borghi C, Charchar F, et al.. 2020 International Society of Hypertension global hypertension practice guidelines. Hypertension. 2020, 75:1334-57. 10.1161\/HYPERTENSIONAHA.120.15026","journal-title":"Hypertension"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1038\/s41371-020-0349-x","article-title":"Indian guidelines on hypertension-IV (2019)","volume":"34","author":"Shah SN","year":"2020","unstructured":"Shah SN, Munjal YP, Kamath SA, et al.. Indian guidelines on hypertension-IV (2019). J Hum Hypertens. 2020, 34:745-58. 10.1038\/s41371-020-0349-x","journal-title":"J Hum Hypertens"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ihj.2014.10.421","article-title":"Prevalence of sympathetic overactivity in hypertensive patients - a pan India, non-interventional, cross sectional study","volume":"66","author":"Padmanabhan TN","year":"2014","unstructured":"Padmanabhan TN, Dani S, Chopra VK, Guha S, Vasnawala H, Ammar R. Prevalence of sympathetic overactivity in hypertensive patients - a pan India, non-interventional, cross sectional study. Indian Heart J. 2014, 66:686-90. 10.1016\/j.ihj.2014.10.421","journal-title":"Indian Heart J"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3283537347","article-title":"Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and difficult to treat arterial hypertension","volume":"30","author":"Jordan J","year":"2012","unstructured":"Jordan J, Yumuk V, Schlaich M, et al.. Joint statement of the European Association for the Study of Obesity and the European Society of Hypertension: obesity and difficult to treat arterial hypertension. J Hypertens. 2012, 30:1047-55. 10.1097\/HJH.0b013e3283537347","journal-title":"J Hypertens"},{"key":"ref21","article-title":"Hypertension in young adults in India: perspectives and therapeutic options amongst clinician\u2019s in a cross sectional observational study","volume":"69","author":"Jadhav U","year":"2021","unstructured":"Jadhav U, Tiwaskar M, Khan A, et al.. Hypertension in young adults in India: perspectives and therapeutic options amongst clinician\u2019s in a cross sectional observational study. J Assoc Physicians India. 2021, 69:11-2.","journal-title":"J Assoc Physicians India"},{"key":"ref22","unstructured":"ICH Guideline E6, Guideline For Good Clinical Practice, 1 May 1996. (2016). Accessed. October 23, 2023: https:\/\/database.ich.org\/sites\/default\/files\/E6_R2_Addendum.pdf."},{"key":"ref23","unstructured":"World Medical Association. Declaration of Helsinki. medical research involving human participants. (2023). Accessed: October 23, 2023: https:\/\/www.wma.net\/what-we-do\/medical-ethics\/declaration-of-helsinki\/."},{"key":"ref24","article-title":"Guidelines for good epidemiology practices for occupational and environmental epidemiologic research","volume":"33","author":"The Chemical Manufacturers Association\u2019s Epidemiology Task Group","year":"1991","unstructured":"The Chemical Manufacturers Association\u2019s Epidemiology Task Group. Guidelines for good epidemiology practices for occupational and environmental epidemiologic research. J Occup Med. 1991, 33:1221-9.","journal-title":"J Occup Med"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.119.13820","article-title":"Investigation and treatment of high blood pressure in young people: too much medicine or appropriate risk reduction?","volume":"75","author":"Hinton TC","year":"2020","unstructured":"Hinton TC, Adams ZH, Baker RP, Hope KA, Paton JF, Hart EC, Nightingale AK. Investigation and treatment of high blood pressure in young people: too much medicine or appropriate risk reduction?. Hypertension. 2020, 75:16-22. 10.1161\/HYPERTENSIONAHA.119.13820","journal-title":"Hypertension"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-011-0191-1","article-title":"Sympathetic neural mechanisms in human blood pressure regulation","volume":"13","author":"Hart EC","year":"2011","unstructured":"Hart EC, Charkoudian N. Sympathetic neural mechanisms in human blood pressure regulation. Curr Hypertens Rep. 2011, 13:237-43. 10.1007\/s11906-011-0191-1","journal-title":"Curr Hypertens Rep"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s11886-017-0912-4","article-title":"Hypertension in obesity and the impact of weight loss","volume":"19","author":"Cohen JB","year":"2017","unstructured":"Cohen JB. Hypertension in obesity and the impact of weight loss. Curr Cardiol Rep. 2017, 19:98. 10.1007\/s11886-017-0912-4","journal-title":"Curr Cardiol Rep"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1161\/HYP.0000000000000195","article-title":"Management of stage 1 hypertension in adults with a low 10-year risk for cardiovascular disease: filling a guidance gap: a scientific statement from the American Heart Association","volume":"77","author":"Jones DW","year":"2021","unstructured":"Jones DW, Whelton PK, Allen N, et al.. Management of stage 1 hypertension in adults with a low 10-year risk for cardiovascular disease: filling a guidance gap: a scientific statement from the American Heart Association. Hypertension. 2021, 77:e58-67. 10.1161\/HYP.0000000000000195","journal-title":"Hypertension"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.4065\/84.9.822","article-title":"Sympathetic neural mechanisms in human cardiovascular health and disease","volume":"84","author":"Charkoudian N","year":"2009","unstructured":"Charkoudian N, Rabbitts JA. Sympathetic neural mechanisms in human cardiovascular health and disease. Mayo Clin Proc. 2009, 84:822-30. 10.4065\/84.9.822","journal-title":"Mayo Clin Proc"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.101.25.2981","article-title":"Left ventricular remodeling after myocardial infarction: pathophysiology and therapy","volume":"101","author":"Sutton MG","year":"2000","unstructured":"Sutton MG, Sharpe N. Left ventricular remodeling after myocardial infarction: pathophysiology and therapy. Circulation. 2000, 101:2981-8. 10.1161\/01.cir.101.25.2981","journal-title":"Circulation"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehs299","article-title":"Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency","volume":"34","author":"Lam CS","year":"2013","unstructured":"Lam CS, Shah AM, Borlaug BA, et al.. Effect of antihypertensive therapy on ventricular-arterial mechanics, coupling, and efficiency. Eur Heart J. 2013, 34:676-83. 10.1093\/eurheartj\/ehs299","journal-title":"Eur Heart J"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12049","article-title":"Obesity-related hypertension: pathogenesis, cardiovascular risk, and treatment: a position paper of the Obesity Society and the American Society of Hypertension","volume":"15","author":"Landsberg L","year":"2013","unstructured":"Landsberg L, Aronne LJ, Beilin LJ, Burke V, Igel LI, Lloyd-Jones D, Sowers J. Obesity-related hypertension: pathogenesis, cardiovascular risk, and treatment: a position paper of the Obesity Society and the American Society of Hypertension. J Clin Hypertens (Greenwich). 2013, 15:14-33. 10.1111\/jch.12049","journal-title":"J Clin Hypertens (Greenwich)"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s11906-005-0065-5","article-title":"Management of hypertension in overweight and obese patients: a practical guide for clinicians","volume":"7","author":"Dentali F","year":"2005","unstructured":"Dentali F, Sharma AM, Douketis JD. Management of hypertension in overweight and obese patients: a practical guide for clinicians. Curr Hypertens Rep. 2005, 7:330-6. 10.1007\/s11906-005-0065-5","journal-title":"Curr Hypertens Rep"},{"key":"ref34","article-title":"How to treat hypertension in the obese. An article from the e-journal of the ESC Council for Cardiology Practice","volume":"12","author":"Grassi G","year":"2013","unstructured":"Grassi G. How to treat hypertension in the obese. An article from the e-journal of the ESC Council for Cardiology Practice. EJ Cardiol Pract. 2013, 12:","journal-title":"EJ Cardiol Pract"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/266975-obesity-and-sympathetic-overactivity-in-young-individuals-with-hypertension-clinical-perspective-of-indian-healthcare-providers","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,20]],"date-time":"2024-11-20T23:57:46Z","timestamp":1732147066000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/266975-obesity-and-sympathetic-overactivity-in-young-individuals-with-hypertension-clinical-perspective-of-indian-healthcare-providers"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,20]]},"references-count":34,"URL":"https:\/\/doi.org\/10.7759\/cureus.74115","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,20]]}}}