{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,4]],"date-time":"2026-06-04T01:47:41Z","timestamp":1780537661297,"version":"3.54.1"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,25]]},"DOI":"10.7759\/cureus.74462","type":"journal-article","created":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T07:05:56Z","timestamp":1732604756000},"source":"Crossref","is-referenced-by-count":2,"title":["Alobar Holoprosencephaly in a Newborn: A Case Report of Prenatal Diagnosis and a Review of the Literature"],"prefix":"10.7759","author":[{"given":"Kamal","family":"Chafiq","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Khalil","family":"Toumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fatima Ezzahra","family":"Khayi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdellatif","family":"Daoudi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/children10040647","article-title":"Holoprosencephaly: review of embryology, clinical phenotypes, etiology and management","volume":"10","author":"Malta M","year":"2023","unstructured":"Malta M, AlMutiri R, Martin CS, Srour M. Holoprosencephaly: review of embryology, clinical phenotypes, etiology and management. Children (Basel). 2023, 10:647. 10.3390\/children10040647","journal-title":"Children (Basel)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30233","article-title":"Epidemiology of holoprosencephaly: prevalence and risk factors","volume":"154C","author":"Orioli IM","year":"2010","unstructured":"Orioli IM, Castilla EE. Epidemiology of holoprosencephaly: prevalence and risk factors. Am J Med Genet C Semin Med Genet. 2010, 154C:13-21. 10.1002\/ajmg.c.30233","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1159\/000104278","article-title":"Alobar holoprosencephaly (arhinencephaly) with median cleft lip and palate: clinical, electroencephalographic and nosologic considerations","volume":"23","author":"Demyer W","year":"1963","unstructured":"Demyer W, Zeman W. Alobar holoprosencephaly (arhinencephaly) with median cleft lip and palate: clinical, electroencephalographic and nosologic considerations. Confin Neurol. 1963, 23:1-36. 10.1159\/000104278","journal-title":"Confin Neurol"},{"key":"ref4","article-title":"Middle interhemispheric fusion: an unusual variant of holoprosencephaly","volume":"14","author":"Barkovich AJ","year":"1993","unstructured":"Barkovich AJ, Quint DJ. Middle interhemispheric fusion: an unusual variant of holoprosencephaly. AJNR Am J Neuroradiol. 1993, 14:431-40.","journal-title":"AJNR Am J Neuroradiol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s11604-024-01655-8","article-title":"Holoprosencephaly spectrum: an up-to-date overview of classification, genetics and neuroimaging","author":"Gomez GD","year":"2024","unstructured":"Gomez GD, Corr\u00eaa DG, Trapp B, et al.. Holoprosencephaly spectrum: an up-to-date overview of classification, genetics and neuroimaging. Jpn J Radiol. 2024, 10.1007\/s11604-024-01655-8","journal-title":"Jpn J Radiol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.795194","article-title":"Concepts in multifactorial etiology of developmental disorders: gene-gene and gene-environment interactions in holoprosencephaly","volume":"9","author":"Lo HF","year":"2021","unstructured":"Lo HF, Hong M, Krauss RS. Concepts in multifactorial etiology of developmental disorders: gene-gene and gene-environment interactions in holoprosencephaly. Front Cell Dev Biol. 2021, 9:795194. 10.3389\/fcell.2021.795194","journal-title":"Front Cell Dev Biol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1148\/rg.351140040","article-title":"Holoprosencephaly: a survey of the entity, with embryology and fetal imaging","volume":"35","author":"Winter TC","year":"2015","unstructured":"Winter TC, Kennedy AM, Woodward PJ. Holoprosencephaly: a survey of the entity, with embryology and fetal imaging. Radiographics. 2015, 35:275-90. 10.1148\/rg.351140040","journal-title":"Radiographics"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.31614","article-title":"Nongenetic risk factors for holoprosencephaly: an updated review of the epidemiologic literature","volume":"178","author":"Summers AD","year":"2018","unstructured":"Summers AD, Reefhuis J, Taliano J, Rasmussen SA. Nongenetic risk factors for holoprosencephaly: an updated review of the epidemiologic literature. Am J Med Genet C Semin Med Genet. 2018, 178:151-64. 10.1002\/ajmg.c.31614","journal-title":"Am J Med Genet C Semin Med Genet"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.nic.2019.03.003","article-title":"Disorders of ventral induction\/spectrum of holoprosencephaly","volume":"29","author":"Calloni SF","year":"2019","unstructured":"Calloni SF, Caschera L, Triulzi FM. Disorders of ventral induction\/spectrum of holoprosencephaly. Neuroimaging Clin N Am. 2019, 29:411-21. 10.1016\/j.nic.2019.03.003","journal-title":"Neuroimaging Clin N Am"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1002\/ajmg.c.30254","article-title":"Management of children with holoprosencephaly","volume":"154C","author":"Levey EB","year":"2010","unstructured":"Levey EB, Stashinko E, Clegg NJ, Delgado MR. Management of children with holoprosencephaly. Am J Med Genet C Semin Med Genet. 2010, 154C:183-90. 10.1002\/ajmg.c.30254","journal-title":"Am J Med Genet C Semin Med Genet"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/318656-alobar-holoprosencephaly-in-a-newborn-a-case-report-of-prenatal-diagnosis-and-a-review-of-the-literature","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,26]],"date-time":"2024-11-26T07:05:57Z","timestamp":1732604757000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/318656-alobar-holoprosencephaly-in-a-newborn-a-case-report-of-prenatal-diagnosis-and-a-review-of-the-literature"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,25]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.74462","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,25]]}}}