{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T20:03:17Z","timestamp":1780344197234,"version":"3.54.1"},"reference-count":44,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,11,29]]},"DOI":"10.7759\/cureus.74730","type":"journal-article","created":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T11:54:33Z","timestamp":1732881273000},"source":"Crossref","is-referenced-by-count":1,"title":["Sex Assignment in Cases of Ambiguous Genitalia"],"prefix":"10.7759","author":[{"given":"Hajira","family":"Mohammed","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nesa","family":"Ansari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ahmed Zafar","family":"Baig","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joud  J","family":"Alshowaikhat","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madiha M","family":"Uz Zama","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jumana","family":"Hussain Timraz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ruqayyah A","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mohommad","family":"Samy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.36347","article-title":"Sex assignment and re-assignment: a pediatric endocrinologist perspective; more than three decades of experience","author":"Al Jurayyan NAM","year":"2015","unstructured":"Al Jurayyan NAM. Sex assignment and re-assignment: a pediatric endocrinologist perspective; more than three decades of experience. Semantic Scholar. 2015, 10.36347","journal-title":"Semantic Scholar"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2014-0503","article-title":"The spectrum of 46XY disorders of sex development in a University centre in Saudi Arabia","volume":"28","author":"Al-Jurayyan NA","year":"2015","unstructured":"Al-Jurayyan NA, Al Issa SD, Al Nemri AM, Al Otaibi HM, Babiker AM. The spectrum of 46XY disorders of sex development in a University centre in Saudi Arabia. J Pediatr Endocrinol Metab. 2015, 28:1123-7. 10.1515\/jpem-2014-0503","journal-title":"J Pediatr Endocrinol Metab"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsbmb.2020.105736","article-title":"Molecular genetics of disorders of sex development in a highly consanguineous population","volume":"208","author":"Alswailem M","year":"2021","unstructured":"Alswailem M, Alsagheir A, Abbas BB, Alzahrani O, Alzahrani AS. Molecular genetics of disorders of sex development in a highly consanguineous population. J Steroid Biochem Mol Biol. 2021, 208:105736. 10.1016\/j.jsbmb.2020.105736","journal-title":"J Steroid Biochem Mol Biol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.17352\/ijcem.000061","article-title":"Disorders of sex development (DSD): a more than three decades of experience at a major teaching hospital","volume":"10","author":"Al-Jurayyan NAM","year":"2024","unstructured":"Al-Jurayyan NAM. Disorders of sex development (DSD): a more than three decades of experience at a major teaching hospital. Int J Clin Endocrinol Metab. 2024, 10:014-7. 10.17352\/ijcem.000061","journal-title":"Int J Clin Endocrinol Metab"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2350\/14-04-1466-PB.1","article-title":"Perspectives in pediatric pathology, chapter 7. Ovotesticular DSD (true hermaphroditism)","volume":"18","author":"Nistal M","year":"2015","unstructured":"Nistal M, Paniagua R, Gonz\u00e1lez-Peramato P, Reyes-M\u00fagica M. Perspectives in pediatric pathology, chapter 7. Ovotesticular DSD (true hermaphroditism). Pediatr Dev Pathol. 2015, 18:345-52. 10.2350\/14-04-1466-PB.1","journal-title":"Pediatr Dev Pathol"},{"key":"ref6","article-title":"Ambiguous Genitalia in the Newborn","author":"Fl\u00fcck CE","year":"2000","unstructured":"Fl\u00fcck CE, G\u00fcran T. Ambiguous Genitalia in the Newborn. Feingold KR, Anawalt B, Blackman MR, et al. (ed): MDText.com, Inc., South Dartmouth; 2000."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2019.00316","article-title":"What term to choose: ambiguous genitalia or disorders of sex development (DSD)?","volume":"7","author":"Acimi S","year":"2019","unstructured":"Acimi S. What term to choose: ambiguous genitalia or disorders of sex development (DSD)?. Front Pediatr. 2019, 7:316. 10.3389\/fped.2019.00316","journal-title":"Front Pediatr"},{"key":"ref8","article-title":"Androgen Insensitivity Syndrome","author":"Singh S","year":"2024","unstructured":"Singh S, Ilyayeva S. Androgen Insensitivity Syndrome. StatPearls, Treasure Island, FL; 2024."},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2017.10.038","article-title":"Mutational analysis of the androgen receptor (NR3C4) gene in patients with 46,XY DSD","volume":"641","author":"Ramos L","year":"2018","unstructured":"Ramos L, Ch\u00e1vez B, Mares L, Vald\u00e9s E, Vilchis F. Mutational analysis of the androgen receptor (NR3C4) gene in patients with 46,XY DSD. Gene. 2018, 641:86-93. 10.1016\/j.gene.2017.10.038","journal-title":"Gene"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2016-1372","article-title":"The long-term outcome of boys with partial androgen insensitivity syndrome and a mutation in the androgen receptor gene","volume":"101","author":"Lucas-Herald A","year":"2016","unstructured":"Lucas-Herald A, Bertelloni S, Juul A, et al.. The long-term outcome of boys with partial androgen insensitivity syndrome and a mutation in the androgen receptor gene. J Clin Endocrinol Metab. 2016, 101:3959-67. 10.1210\/jc.2016-1372","journal-title":"J Clin Endocrinol Metab"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4238\/gmr.15018232","article-title":"Correlation of androgen receptor and SRD5A2 gene mutations with pediatric hypospadias in 46, XY DSD children","volume":"15","author":"Fu XH","year":"2016","unstructured":"Fu XH, Zhang WQ, Qu XS. Correlation of androgen receptor and SRD5A2 gene mutations with pediatric hypospadias in 46, XY DSD children. Genet Mol Res. 2016, 15:15018232. 10.4238\/gmr.15018232","journal-title":"Genet Mol Res"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1515\/jpem-2014-0500","article-title":"Investigation of androgen receptor gene mutations in a series of 21 patients with 46,XY disorders of sex development","volume":"28","author":"Topcu V","year":"2015","unstructured":"Topcu V, Ilgin-Ruhi H, Siklar Z, et al.. Investigation of androgen receptor gene mutations in a series of 21 patients with 46,XY disorders of sex development. J Pediatr Endocrinol Metab. 2015, 28:1257-63. 10.1515\/jpem-2014-0500","journal-title":"J Pediatr Endocrinol Metab"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.sempedsurg.2019.150841","article-title":"Clinical management in mixed gonadal dysgenesis with chromosomal mosaicism: Considerations in newborns and adolescents","volume":"28","author":"Weidler EM","year":"2019","unstructured":"Weidler EM, Pearson M, van Leeuwen K, Garvey E. Clinical management in mixed gonadal dysgenesis with chromosomal mosaicism: Considerations in newborns and adolescents. Semin Pediatr Surg. 2019, 28:150841. 10.1016\/j.sempedsurg.2019.150841","journal-title":"Semin Pediatr Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2014-2605","article-title":"Exome sequencing for the diagnosis of 46,XY disorders of sex development","volume":"100","author":"Baxter RM","year":"2015","unstructured":"Baxter RM, Arboleda VA, Lee H, et al.. Exome sequencing for the diagnosis of 46,XY disorders of sex development. J Clin Endocrinol Metab. 2015, 100:E333-44. 10.1210\/jc.2014-2605","journal-title":"J Clin Endocrinol Metab"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2017.03.016","article-title":"Genetic approach to ambiguous genitalia and disorders of sex development: what clinicians need to know","volume":"41","author":"Yatsenko SA","year":"2017","unstructured":"Yatsenko SA, Witchel SF. Genetic approach to ambiguous genitalia and disorders of sex development: what clinicians need to know. Semin Perinatol. 2017, 41:232-43. 10.1053\/j.semperi.2017.03.016","journal-title":"Semin Perinatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0287515","article-title":"Genetic reanalysis of patients with a difference of sex development carrying the NR5A1\/SF-1 variant p.Gly146Ala has discovered other likely disease-causing variations","volume":"18","author":"Martinez de Lapiscina I","year":"2023","unstructured":"Martinez de Lapiscina I, Kouri C, Aurrekoetxea J, et al.. Genetic reanalysis of patients with a difference of sex development carrying the NR5A1\/SF-1 variant p.Gly146Ala has discovered other likely disease-causing variations. PLoS One. 2023, 18:e0287515. 10.1371\/journal.pone.0287515","journal-title":"PLoS One"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1177\/2042018817746291","article-title":"Current best practice in the management of Turner syndrome","volume":"9","author":"Shankar RK","year":"2018","unstructured":"Shankar RK, Backeljauw PF. Current best practice in the management of Turner syndrome. Ther Adv Endocrinol Metab. 2018, 9:33-40. 10.1177\/2042018817746291","journal-title":"Ther Adv Endocrinol Metab"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.21037\/pm-22-9","article-title":"Turner syndrome: narrative review of genetics and clinical aspects of management","volume":"28","author":"Fudge EB","year":"2024","unstructured":"Fudge EB. Turner syndrome: narrative review of genetics and clinical aspects of management. Pediatr Med. 2024, 28:7. 10.21037\/pm-22-9","journal-title":"Pediatr Med"},{"key":"ref19","article-title":"Klinefelter Syndrome","author":"Los E","year":"2023","unstructured":"Los E. Klinefelter Syndrome. U.S. National Library of Medicine. 2023,","journal-title":"U.S. National Library of Medicine"},{"key":"ref20","article-title":"Congenital Adrenal Hyperplasia","author":"Yau M","year":"2000","unstructured":"Yau M, Khattab A, Yuen T, et al.. Congenital Adrenal Hyperplasia. Feingold KR, Anawalt B, Blackman MR, et al. (ed): MDText.com, Inc., South Dartmouth; 2000."},{"key":"ref21","article-title":"21-Hydroxylase-Deficient Congenital Adrenal Hyperplasia","author":"Nimkarn S","year":"2002","unstructured":"Nimkarn S, Gangishetti PK, Yau M, et al.. 21-Hydroxylase-Deficient Congenital Adrenal Hyperplasia. University of Washington, Seattle; 2002."},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpag.2017.04.001","article-title":"Congenital adrenal hyperplasia","volume":"30","author":"Witchel SF","year":"2017","unstructured":"Witchel SF. Congenital adrenal hyperplasia. J Pediatr Adolesc Gynecol. 2017, 30:520-34. 10.1016\/j.jpag.2017.04.001","journal-title":"J Pediatr Adolesc Gynecol"},{"key":"ref23","article-title":"Congenital Adrenal Hyperplasia","author":"Momodu II","year":"2020","unstructured":"Momodu II, Lee B, Singh G. Congenital Adrenal Hyperplasia. StatPearls Publishing, Treasure Island, FL; 2020."},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.beem.2007.06.003","article-title":"Consequences of the ESPE\/LWPES guidelines for diagnosis and treatment of disorders of sex development","volume":"21","author":"Hughes IA","year":"2007","unstructured":"Hughes IA, Nihoul-F\u00e9k\u00e9t\u00e9 C, Thomas B, Cohen-Kettenis PT. Consequences of the ESPE\/LWPES guidelines for diagnosis and treatment of disorders of sex development. Best Pract Res Clin Endocrinol Metab. 2007, 21:351-65. 10.1016\/j.beem.2007.06.003","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.21699\/jns.v6i3.604","article-title":"Neonatal sex assignment in disorders of sex development: a philosophical introspection","volume":"6","author":"Raveenthiran V","year":"2017","unstructured":"Raveenthiran V. Neonatal sex assignment in disorders of sex development: a philosophical introspection. J Neonatal Surg. 2017, 6:58. 10.21699\/jns.v6i3.604","journal-title":"J Neonatal Surg"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.4274\/jcrpe.galenos.2020.2020.0009","article-title":"Gender Identity and assignment recommendations in disorders of sex development patients: 20 Years\u2019 experience and challenges","volume":"12","author":"G\u00fcrb\u00fcz F","year":"2020","unstructured":"G\u00fcrb\u00fcz F, Alkan M, \u00c7elik G, et al.. Gender Identity and assignment recommendations in disorders of sex development patients: 20 Years\u2019 experience and challenges. J Clin Res Pediatr Endocrinol. 2020, 12:347-57. 10.4274\/jcrpe.galenos.2020.2020.0009","journal-title":"J Clin Res Pediatr Endocrinol"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ando.2014.03.008","article-title":"Long-term management of patients with disorders of sex development (DSD)","volume":"75","author":"Hiort O","year":"2014","unstructured":"Hiort O. Long-term management of patients with disorders of sex development (DSD). Ann Endocrinol (Paris). 2014, 75:64-6. 10.1016\/j.ando.2014.03.008","journal-title":"Ann Endocrinol (Paris)"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1530\/EJE-18-0256","article-title":"Genetics in endocrinology: Approaches to molecular genetic diagnosis in the management of differences\/disorders of sex development (DSD): position paper of EU COST action BM 1303 \"DSDnet\"","volume":"179","author":"Audi L","year":"2018","unstructured":"Audi L, Ahmed SF, Krone N, et al.. Genetics in endocrinology: Approaches to molecular genetic diagnosis in the management of differences\/disorders of sex development (DSD): position paper of EU COST action BM 1303 \"DSDnet\". Eur J Endocrinol. 2018, 179:R197-206. 10.1530\/EJE-18-0256","journal-title":"Eur J Endocrinol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1186\/1687-9856-2014-4","article-title":"State of the art review in gonadal dysgenesis: challenges in diagnosis and management","volume":"2014","author":"McCann-Crosby B","year":"2014","unstructured":"McCann-Crosby B, Mansouri R, Dietrich JE, et al.. State of the art review in gonadal dysgenesis: challenges in diagnosis and management. Int J Pediatr Endocrinol. 2014, 2014:4. 10.1186\/1687-9856-2014-4","journal-title":"Int J Pediatr Endocrinol"},{"key":"ref30","article-title":"Genetics, Gonadal Dysgenesis","author":"Breehl L","year":"2024","unstructured":"Breehl L, Caban O. Genetics, Gonadal Dysgenesis. StatPearls, Treasure Island, FL; 2024."},{"key":"ref31","article-title":"Abnormal sex determinism: true hermaphrodite (TH)","volume":"1","author":"Hossein RS","year":"2020","unstructured":"Hossein RS, Reza AH. Abnormal sex determinism: true hermaphrodite (TH). J Clin Trans Endocrinol Case Rep. 2020, 1:100070.","journal-title":"J Clin Trans Endocrinol Case Rep"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1159\/000442975","article-title":"Global disorders of sex development update since 2006: perceptions, approach and care","volume":"85","author":"Lee PA","year":"2016","unstructured":"Lee PA, Nordenstr\u00f6m A, Houk CP, et al.. Global disorders of sex development update since 2006: perceptions, approach and care. Horm Res Paediatr. 2016, 85:158-80. 10.1159\/000442975","journal-title":"Horm Res Paediatr"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.4103\/jiaps.JIAPS_70_18","article-title":"A clinical approach to diagnosis of ambiguous genitalia","volume":"24","author":"Khanna K","year":"2019","unstructured":"Khanna K, Sharma S, Gupta DK. A clinical approach to diagnosis of ambiguous genitalia. J Indian Assoc Pediatr Surg. 2019, 24:162-9. 10.4103\/jiaps.JIAPS_70_18","journal-title":"J Indian Assoc Pediatr Surg"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2018.00339","article-title":"Navigating surgical decision making in disorders of sex development (DSD)","volume":"6","author":"Gardner M","year":"2018","unstructured":"Gardner M, Sandberg DE. Navigating surgical decision making in disorders of sex development (DSD). Front Pediatr. 2018, 6:339. 10.3389\/fped.2018.00339","journal-title":"Front Pediatr"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1080\/15476278.2016.1210749","article-title":"Systematization of ambiguous genitalia","volume":"12","author":"Makiyan Z","year":"2016","unstructured":"Makiyan Z. Systematization of ambiguous genitalia. Organogenesis. 2016, 12:169-82. 10.1080\/15476278.2016.1210749","journal-title":"Organogenesis"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2017.09.027","article-title":"Risk association of congenital anomalies in patients with ambiguous genitalia: a 22-year single-center experience","volume":"14","author":"Heeley JM","year":"2018","unstructured":"Heeley JM, Hollander AS, Austin PF, Merritt DF, Wesevich VG, Amarillo IE. Risk association of congenital anomalies in patients with ambiguous genitalia: a 22-year single-center experience. J Pediatr Urol. 2018, 14:153.e1-7. 10.1016\/j.jpurol.2017.09.027","journal-title":"J Pediatr Urol"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1016\/j.sempedsurg.2019.150840","article-title":"The impact of culture on disclosure in differences of sex development","volume":"28","author":"Weidler EM","year":"2019","unstructured":"Weidler EM, Peterson KE. The impact of culture on disclosure in differences of sex development. Semin Pediatr Surg. 2019, 28:150840. 10.1016\/j.sempedsurg.2019.150840","journal-title":"Semin Pediatr Surg"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1007\/s10508-016-0754-y","article-title":"The Islamic perspectives of gender-related issues in the management of patients with disorders of sex development","volume":"46","author":"Zainuddin AA","year":"2017","unstructured":"Zainuddin AA, Mahdy ZA. The Islamic perspectives of gender-related issues in the management of patients with disorders of sex development. Arch Sex Behav. 2017, 46:353-60. 10.1007\/s10508-016-0754-y","journal-title":"Arch Sex Behav"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.2147\/AGG.S53226","article-title":"Disorders of sex development: advances in genetic diagnosis and challenges in management","volume":"8","author":"Kyriakou A","year":"2015","unstructured":"Kyriakou A, Lucas-Herald AK, McGowan R, Tobias ES, Ahmed SF. Disorders of sex development: advances in genetic diagnosis and challenges in management. Adv Genom Genet. 2015, 8:165-77. 10.2147\/AGG.S53226","journal-title":"Adv Genom Genet"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpurol.2020.11.017","article-title":"Gender identity disorder (GID) in adolescents and adults with differences of sex development (DSD): a systematic review and meta-analysis","volume":"17","author":"Babu R","year":"2021","unstructured":"Babu R, Shah U. Gender identity disorder (GID) in adolescents and adults with differences of sex development (DSD): a systematic review and meta-analysis. J Pediatr Urol. 2021, 17:39-47. 10.1016\/j.jpurol.2020.11.017","journal-title":"J Pediatr Urol"},{"key":"ref41","article-title":"Initial assessment of a child with suspected disorder of sex development","volume":"69","author":"Ahmad A","year":"2019","unstructured":"Ahmad A, Ayub F, Saleem I, Ahmad N. Initial assessment of a child with suspected disorder of sex development. J Pak Med Assoc. 2019, 69:711-7.","journal-title":"J Pak Med Assoc"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-018-0010-8","article-title":"Caring for individuals with a difference of sex development (DSD): a consensus statement","volume":"14","author":"Cools M","year":"2018","unstructured":"Cools M, Nordenstr\u00f6m A, Robeva R, et al.. Caring for individuals with a difference of sex development (DSD): a consensus statement. Nat Rev Endocrinol. 2018, 14:415-29. 10.1038\/s41574-018-0010-8","journal-title":"Nat Rev Endocrinol"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1186\/s13256-021-02914-2","article-title":"Ambiguous genitalia: clinical management of adult female with male assigned gender: a case report","volume":"15","author":"Ali MA","year":"2021","unstructured":"Ali MA, Maalman RS, Donkor YO, Mensah JE. Ambiguous genitalia: clinical management of adult female with male assigned gender: a case report. J Med Case Rep. 2021, 15:362. 10.1186\/s13256-021-02914-2","journal-title":"J Med Case Rep"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2014.83","article-title":"Malformation syndromes associated with disorders of sex development","volume":"10","author":"Hutson JM","year":"2014","unstructured":"Hutson JM, Grover SR, O'Connell M, Pennell SD. Malformation syndromes associated with disorders of sex development. Nat Rev Endocrinol. 2014, 10:476-87. 10.1038\/nrendo.2014.83","journal-title":"Nat Rev Endocrinol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/315075-sex-assignment-in-cases-of-ambiguous-genitalia","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,11,29]],"date-time":"2024-11-29T11:54:36Z","timestamp":1732881276000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/315075-sex-assignment-in-cases-of-ambiguous-genitalia"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,11,29]]},"references-count":44,"URL":"https:\/\/doi.org\/10.7759\/cureus.74730","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,11,29]]}}}