{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T12:11:05Z","timestamp":1790683865561,"version":"4.1.0"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,12,21]]},"DOI":"10.7759\/cureus.76121","type":"journal-article","created":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T11:56:41Z","timestamp":1734782201000},"source":"Crossref","is-referenced-by-count":1,"title":["Dasatinib-Induced Gynecomastia: A Case Report"],"prefix":"10.7759","author":[{"given":"Himanshi","family":"Kaushik","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kanchan D","family":"Devde","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nishtha","family":"Manuja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rahul","family":"Arora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amol","family":"Dongre","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/canjclin.55.2.74","article-title":"Global cancer statistics, 2002","volume":"55","author":"Parkin DM","year":"2005","unstructured":"Parkin DM, Bray F, Ferlay J, Pisani P. Global cancer statistics, 2002. CA Cancer J Clin. 2005, 55:74-108. 10.3322\/canjclin.55.2.74","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-07-102061","article-title":"Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets","volume":"110","author":"Rix U","year":"2007","unstructured":"Rix U, Hantschel O, D\u00fcrnberger G, et al.. Chemical proteomic profiles of the BCR-ABL inhibitors imatinib, nilotinib, and dasatinib reveal novel kinase and nonkinase targets. Blood. 2007, 110:4055-63. 10.1182\/blood-2007-07-102061","journal-title":"Blood"},{"key":"ref3","unstructured":"Gleevec (imatinib mesylate) tablets, for oral use. Prescribing information. (2022). Accessed. July 21, 2024: http:\/\/www.novartis.us\/sites\/www.novartis.us\/files\/gleevec_tabs.pdf."},{"key":"ref4","unstructured":"Sprycel prescribing information. (2021). Accessed. July 21, 2024: https:\/\/packageinserts.bms.com\/pi\/pi_sprycel.pdf."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13554-4","article-title":"Gynaecomastia in men with chronic myeloid leukaemia after imatinib","volume":"361","author":"Gambacorti-Passerini C","year":"2003","unstructured":"Gambacorti-Passerini C, Tornaghi L, Cavagnini F, et al.. Gynaecomastia in men with chronic myeloid leukaemia after imatinib. Lancet. 2003, 361:1954-6. 10.1016\/S0140-6736(03)13554-4","journal-title":"Lancet"},{"key":"ref6","article-title":"Gynecomastia: Etiology, Diagnosis, and Treatment","author":"Swerdloff RS","year":"2000","unstructured":"Swerdloff RS, Ng JCM. Gynecomastia: Etiology, Diagnosis, and Treatment. Feingold KR, Anawalt B, Blackman MR, et al. (ed): Endotext [Internet], South Dartmouth (MA); 2000."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1210\/er.2010-0004","article-title":"Role of platelet-derived growth factors in the testis","volume":"31","author":"Basciani S","year":"2010","unstructured":"Basciani S, Mariani S, Spera G, Gnessi L. Role of platelet-derived growth factors in the testis. Endocr Rev. 2010, 31:916-39. 10.1210\/er.2010-0004","journal-title":"Endocr Rev"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1723908","article-title":"The PDGF signaling pathway controls multiple steroid-producing lineages","volume":"22","author":"Schmahl J","year":"2008","unstructured":"Schmahl J, Rizzolo K, Soriano P. The PDGF signaling pathway controls multiple steroid-producing lineages. Genes Dev. 2008, 22:3255-67. 10.1101\/gad.1723908","journal-title":"Genes Dev"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4274\/TJH-2013-0109","article-title":"Gynecomastia in a boy with chronic myeloid leukemia during imatinib therapy","volume":"30","author":"Tavil B","year":"2013","unstructured":"Tavil B, K\u0131n\u0131k S, G\u00f6zen A, Olcay L. Gynecomastia in a boy with chronic myeloid leukemia during imatinib therapy. Turk J Haematol. 2013, 30:336-7. 10.4274\/TJH-2013-0109","journal-title":"Turk J Haematol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1177\/1078155213500686","article-title":"Effect of imatinib on male reproductive hormones in BCR-ABL positive CML patients: a preliminary report","volume":"20","author":"Ghalaut VS","year":"2014","unstructured":"Ghalaut VS, Prakash G, Bansal P, et al.. Effect of imatinib on male reproductive hormones in BCR-ABL positive CML patients: a preliminary report. J Oncol Pharm Pract. 2014, 20:243-8. 10.1177\/1078155213500686","journal-title":"J Oncol Pharm Pract"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.40692","article-title":"Chronic myeloid leukemia presenting as non-cirrhotic portal hypertension","volume":"15","author":"Gemnani RR Jr","year":"2023","unstructured":"Gemnani RR Jr, Parepalli A, Kumar S, Acharya S, Shukla S. Chronic myeloid leukemia presenting as non-cirrhotic portal hypertension. Cureus. 2023, 15:e40692. 10.7759\/cureus.40692","journal-title":"Cureus"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-11-116","article-title":"Gynecomastia during imatinib mesylate treatment for gastrointestinal stromal tumor: a rare adverse event","volume":"11","author":"Liu H","year":"2011","unstructured":"Liu H, Liao G, Yan Z. Gynecomastia during imatinib mesylate treatment for gastrointestinal stromal tumor: a rare adverse event. BMC Gastroenterol. 2011, 11:116. 10.1186\/1471-230X-11-116","journal-title":"BMC Gastroenterol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1038\/nrendo.2014.139","article-title":"Gynaecomastia--pathophysiology, diagnosis and treatment","volume":"10","author":"Narula HS","year":"2014","unstructured":"Narula HS, Carlson HE. Gynaecomastia--pathophysiology, diagnosis and treatment. Nat Rev Endocrinol. 2014, 10:684-98. 10.1038\/nrendo.2014.139","journal-title":"Nat Rev Endocrinol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2005.20.3.512","article-title":"Concurrent male gynecomastia and testicular hydrocele after imatinib mesylate treatment of a gastrointestinal stromal tumor","volume":"20","author":"Kim H","year":"2005","unstructured":"Kim H, Chang HM, Ryu MH, et al.. Concurrent male gynecomastia and testicular hydrocele after imatinib mesylate treatment of a gastrointestinal stromal tumor. J Korean Med Sci. 2005, 20:512-5. 10.3346\/jkms.2005.20.3.512","journal-title":"J Korean Med Sci"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1177\/1078155211424629","article-title":"Imatinib-associated bilateral gynecomastia and unilateral testicular hydrocele in male patient with metastatic gastrointestinal stromal tumor: a literature review","volume":"18","author":"Tanriverdi O","year":"2012","unstructured":"Tanriverdi O, Unubol M, Taskin F, Meydan N, Sargin G, Guney E, Barutca S. Imatinib-associated bilateral gynecomastia and unilateral testicular hydrocele in male patient with metastatic gastrointestinal stromal tumor: a literature review. J Oncol Pharm Pract. 2012, 18:303-10. 10.1177\/1078155211424629","journal-title":"J Oncol Pharm Pract"},{"key":"ref16","article-title":"Dasatinib-induced gynecomastia in 2 patients with chronic myeloid leukemia: case reports and review of the literature","volume":"12","author":"Signorelli J","year":"2022","unstructured":"Signorelli J, Fathi A, Hobbs G. Dasatinib-induced gynecomastia in 2 patients with chronic myeloid leukemia: case reports and review of the literature. J Hematol Oncol Pharm. 2022, 12:24-8.","journal-title":"J Hematol Oncol Pharm"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/281012-dasatinib-induced-gynecomastia-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,21]],"date-time":"2024-12-21T11:56:43Z","timestamp":1734782203000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/281012-dasatinib-induced-gynecomastia-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,21]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.76121","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12,21]]}}}