{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T03:10:21Z","timestamp":1736046621370,"version":"3.32.0"},"reference-count":17,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,4]]},"DOI":"10.7759\/cureus.76921","type":"journal-article","created":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T02:36:52Z","timestamp":1736044612000},"source":"Crossref","is-referenced-by-count":0,"title":["Clinical Outcomes and Healthcare Utilization in Pulmonary Embolism Patients With and Without Prothrombin G20210A Mutation: A National Retrospective Cohort Study"],"prefix":"10.7759","author":[{"given":"Fahmida","family":"Sultana","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ribaba","family":"Rayan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tasnim Jabbar","family":"Brishti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iffath","family":"Mizan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabrina","family":"Sifat","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"FNU","family":"Ifatujjahan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan Carlos","family":"Sequeira Gross","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Garry Aliosha","family":"Francis Morel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(82)90764-1","article-title":"Factors associated with correct antemortem diagnosis of major pulmonary embolism","volume":"73","author":"Goldhaber SZ","year":"1982","unstructured":"Goldhaber SZ, Hennekens CH, Evans DA, Newton EC, Godleski JJ. Factors associated with correct antemortem diagnosis of major pulmonary embolism. Am J Med. 1982, 73:822-6. 10.1016\/0002-9343(82)90764-1","journal-title":"Am J Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/01.ccm.0000171207.95319.b2","article-title":"Deep venous thrombosis in medical-surgical critically ill patients: prevalence, incidence, and risk factors","volume":"33","author":"Cook D","year":"2005","unstructured":"Cook D, Crowther M, Meade M, et al.. Deep venous thrombosis in medical-surgical critically ill patients: prevalence, incidence, and risk factors. Crit Care Med. 2005, 33:1565-71. 10.1097\/01.ccm.0000171207.95319.b2","journal-title":"Crit Care Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa010378","article-title":"Severe pulmonary embolism associated with air travel","volume":"345","author":"Lapostolle F","year":"2001","unstructured":"Lapostolle F, Surget V, Borron SW, et al.. Severe pulmonary embolism associated with air travel. N Engl J Med. 2001, 345:779-83. 10.1056\/NEJMoa010378","journal-title":"N Engl J Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2011.40.1810","article-title":"Tumor grade is associated with venous thromboembolism in patients with cancer: results from the Vienna Cancer and Thrombosis Study","volume":"30","author":"Ahlbrecht J","year":"2012","unstructured":"Ahlbrecht J, Dickmann B, Ay C, et al.. Tumor grade is associated with venous thromboembolism in patients with cancer: results from the Vienna Cancer and Thrombosis Study. J Clin Oncol. 2012, 30:3870-5. 10.1200\/JCO.2011.40.1810","journal-title":"J Clin Oncol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.11.6426","article-title":"Pulmonary embolism diagnosis and mortality with pulmonary CT angiography versus ventilation-perfusion scintigraphy: evidence of overdiagnosis with CT?","volume":"198","author":"Sheh SH","year":"2012","unstructured":"Sheh SH, Bellin E, Freeman KD, Haramati LB. Pulmonary embolism diagnosis and mortality with pulmonary CT angiography versus ventilation-perfusion scintigraphy: evidence of overdiagnosis with CT?. AJR Am J Roentgenol. 2012, 198:1340-5. 10.2214\/AJR.11.6426","journal-title":"AJR Am J Roentgenol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2005.06.058","article-title":"Incidence of venous thromboembolism in patients hospitalized with cancer","volume":"119","author":"Stein PD","year":"2006","unstructured":"Stein PD, Beemath A, Meyers FA, Skaf E, Sanchez J, Olson RE. Incidence of venous thromboembolism in patients hospitalized with cancer. Am J Med. 2006, 119:60-8. 10.1016\/j.amjmed.2005.06.058","journal-title":"Am J Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1378\/chest.11-2301","article-title":"Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th Ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"141","author":"Kearon C","year":"2012","unstructured":"Kearon C, Akl EA, Comerota AJ, et al.. Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th Ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2012, 141:e419S-96S. 10.1378\/chest.11-2301","journal-title":"Chest"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2016.02.638","article-title":"Analysis of national trends in admissions for pulmonary embolism","volume":"150","author":"Smith SB","year":"2016","unstructured":"Smith SB, Geske JB, Kathuria P, et al.. Analysis of national trends in admissions for pulmonary embolism. Chest. 2016, 150:35-45. 10.1016\/j.chest.2016.02.638","journal-title":"Chest"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-67105-7","article-title":"The prevalence, risk factors, and outcomes of acute pulmonary embolism complicating sepsis and septic shock: a national inpatient sample analysis","volume":"14","author":"Hasegawa D","year":"2024","unstructured":"Hasegawa D, Sato R, Lee YI, Wang HY, Nishida K, Steiger D. The prevalence, risk factors, and outcomes of acute pulmonary embolism complicating sepsis and septic shock: a national inpatient sample analysis. Sci Rep. 2024, 14:16049. 10.1038\/s41598-024-67105-7","journal-title":"Sci Rep"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s11239-024-02957-4","article-title":"Outcomes of venous thromboembolism in patients with inherited thrombophilia treated with direct oral anticoagulants: insights from the RIETE registry","volume":"57","author":"Cohen O","year":"2024","unstructured":"Cohen O, Kenet G, Levy-Mendelovich S, et al.. Outcomes of venous thromboembolism in patients with inherited thrombophilia treated with direct oral anticoagulants: insights from the RIETE registry. J Thromb Thrombolysis. 2024, 57:710-20. 10.1007\/s11239-024-02957-4","journal-title":"J Thromb Thrombolysis"},{"key":"ref11","article-title":"A single genetic origin for the common prothrombotic G20210A polymorphism in the prothrombin gene","volume":"15","author":"Zivelin A","year":"1998","unstructured":"Zivelin A, Rosenberg N, Faier S, et al.. A single genetic origin for the common prothrombotic G20210A polymorphism in the prothrombin gene. Blood. 1998, 15:1119-24.","journal-title":"Blood"},{"key":"ref12","article-title":"Geographic distribution of the 20210 G to A prothrombin variant","volume":"79","author":"Rosendaal FR","year":"1998","unstructured":"Rosendaal FR, Doggen CJ, Zivelin A, et al.. Geographic distribution of the 20210 G to A prothrombin variant. Thromb Haemost. 1998, 79:706-8.","journal-title":"Thromb Haemost"},{"key":"ref13","unstructured":"Prothrombin G20210A (Factor II Mutation) Resources. (2024). https.\/\/www.stoptheclot.org\/learn_more\/prothrombin-g20210a-factor-ii-mutation\/."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.164.17.1932","article-title":"Prothrombin 20210A mutation: a mild risk factor for venous thromboembolism but not for arterial thrombotic disease and pregnancy-related complications in a family study","volume":"164","author":"Bank I","year":"2004","unstructured":"Bank I, Libourel EJ, Middeldorp S, et al.. Prothrombin 20210A mutation: a mild risk factor for venous thromboembolism but not for arterial thrombotic disease and pregnancy-related complications in a family study. Arch Intern Med. 2004, 164:1932-7. 10.1001\/archinte.164.17.1932","journal-title":"Arch Intern Med"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0000000000000562","article-title":"Global prevalence of prothrombin gene mutation G20210A and implications in women's health: a systematic review","volume":"27","author":"Dziadosz M","year":"2016","unstructured":"Dziadosz M, Baxi LV. Global prevalence of prothrombin gene mutation G20210A and implications in women's health: a systematic review. Blood Coagul Fibrinolysis. 2016, 27:481-9. 10.1097\/MBC.0000000000000562","journal-title":"Blood Coagul Fibrinolysis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1642036","article-title":"Epidemiology, pathophysiology, and natural history of pulmonary embolism","volume":"35","author":"Turetz M","year":"2018","unstructured":"Turetz M, Sideris AT, Friedman OA, Triphathi N, Horowitz JM. Epidemiology, pathophysiology, and natural history of pulmonary embolism. Semin Intervent Radiol. 2018, 35:92-8. 10.1055\/s-0038-1642036","journal-title":"Semin Intervent Radiol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjms.2021.10.025","article-title":"Sudden cardiac arrest in patients with chronic obstructive pulmonary disease: trends and outcomes from the national inpatient sample","volume":"363","author":"Khan MZ","year":"2022","unstructured":"Khan MZ, Munir MB, Khan MU, Balla S. Sudden cardiac arrest in patients with chronic obstructive pulmonary disease: trends and outcomes from the national inpatient sample. Am J Med Sci. 2022, 363:502-10. 10.1016\/j.amjms.2021.10.025","journal-title":"Am J Med Sci"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/312884-clinical-outcomes-and-healthcare-utilization-in-pulmonary-embolism-patients-with-and-without-prothrombin-g20210a-mutation-a-national-retrospective-cohort-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,5]],"date-time":"2025-01-05T02:36:55Z","timestamp":1736044615000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/312884-clinical-outcomes-and-healthcare-utilization-in-pulmonary-embolism-patients-with-and-without-prothrombin-g20210a-mutation-a-national-retrospective-cohort-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,4]]},"references-count":17,"URL":"https:\/\/doi.org\/10.7759\/cureus.76921","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,4]]}}}