{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T00:46:19Z","timestamp":1790210779679,"version":"4.1.0"},"reference-count":24,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,8]]},"DOI":"10.7759\/cureus.77128","type":"journal-article","created":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T10:53:52Z","timestamp":1736333632000},"source":"Crossref","is-referenced-by-count":5,"title":["Actinomyces Species As Emerging Pathogens: An Observational Study of Clinical Infections and Microbiological Implications"],"prefix":"10.7759","author":[{"given":"Abraham A","family":"Ayantunde","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joanne","family":"Kiang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadeem S","family":"Raja","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Javeed","family":"Ahmed","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anjali","family":"Sanghera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Saumya","family":"Venkatesha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew C","family":"Ekwesianya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.d6099","article-title":"Actinomycosis","volume":"343","author":"Wong VK","year":"2011","unstructured":"Wong VK, Turmezei TD, Weston VC. Actinomycosis. BMJ. 2011, 343:d6099. 10.1136\/bmj.d6099","journal-title":"BMJ"},{"key":"ref2","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000003923","article-title":"Clinical features of actinomycosis: a retrospective, multicenter study of 28 cases of miscellaneous presentations","volume":"95","author":"Bonnefond S","year":"2016","unstructured":"Bonnefond S, Catroux M, Melenotte C, Karkowski L, Rolland L, Trouillier S, Raffray L. Clinical features of actinomycosis: a retrospective, multicenter study of 28 cases of miscellaneous presentations. Medicine. 2016, 95:e3923.","journal-title":"Medicine"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00100-14","article-title":"Actinomyces and related organisms in human infections","volume":"28","author":"K\u00f6n\u00f6nen E","year":"2015","unstructured":"K\u00f6n\u00f6nen E, Wade WG. Actinomyces and related organisms in human infections. Clin Microbiol Rev. 2015, 28:419-42. 10.1128\/CMR.00100-14","journal-title":"Clin Microbiol Rev"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.2147\/IDR.S39601","article-title":"Actinomycosis: etiology, clinical features, diagnosis, treatment, and management","volume":"7","author":"Valour F","year":"2014","unstructured":"Valour F, S\u00e9n\u00e9chal A, Dupieux C, et al.. Actinomycosis: etiology, clinical features, diagnosis, treatment, and management. Infect Drug Resist. 2014, 7:183-97. 10.2147\/IDR.S39601","journal-title":"Infect Drug Resist"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00013-11","article-title":"Polymicrobial interactions: impact on pathogenesis and human disease","volume":"25","author":"Peters BM","year":"2012","unstructured":"Peters BM, Jabra-Rizk MA, O'May GA, Costerton JW, Shirtliff ME. Polymicrobial interactions: impact on pathogenesis and human disease. Clin Microbiol Rev. 2012, 25:193-213. 10.1128\/CMR.00013-11","journal-title":"Clin Microbiol Rev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/0378-1119(92)90560-c","article-title":"Actinomycete infections in humans - a review","volume":"15","author":"Schaal KP","year":"1992","unstructured":"Schaal KP, Lee HJ. Actinomycete infections in humans - a review. Gene. 1992, 15:201-11. 10.1016\/0378-1119(92)90560-c","journal-title":"Gene"},{"key":"ref7","unstructured":"The European Committee on Antimicrobial Susceptibility Testing. (2023). http.\/\/www.eucast.org."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinpr.2021.100084","article-title":"Investigation of Actinomyces spp. bacteraemia and associated 1 year mortality in NHS Greater Glasgow and Clyde","volume":"12","author":"Mollet G","year":"2021","unstructured":"Mollet G, Marek A. Investigation of Actinomyces spp. bacteraemia and associated 1 year mortality in NHS Greater Glasgow and Clyde. Clin Infect Pract. 2021, 12:100084. 10.1016\/j.clinpr.2021.100084","journal-title":"Clin Infect Pract"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.03074-15","article-title":"Is the presence of Actinomyces spp. in blood culture always significant?","volume":"54","author":"Jeffery-Smith A","year":"2016","unstructured":"Jeffery-Smith A, Nic-Fhogartaigh C, Millar M. Is the presence of Actinomyces spp. in blood culture always significant?. J Clin Microbiol. 2016, 54:1137-9. 10.1128\/JCM.03074-15","journal-title":"J Clin Microbiol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/medicina57101064","article-title":"Clinical characteristics of Actinomyces viscosus bacteremia","volume":"57","author":"Hsiao YC","year":"2021","unstructured":"Hsiao YC, Lee YH, Ho CM, Tseng CH, Wang JH. Clinical characteristics of Actinomyces viscosus bacteremia. Medicina (Kaunas). 2021, 57:1064. 10.3390\/medicina57101064","journal-title":"Medicina (Kaunas)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.103583","article-title":"A 5-year retrospective study of Actinomyces odontolyticus bacteremia in the state of Qatar, case series","volume":"76","author":"Ali M","year":"2022","unstructured":"Ali M, Razok A, Ziglam H. A 5-year retrospective study of Actinomyces odontolyticus bacteremia in the state of Qatar, case series. Ann Med Surg (Lond). 2022, 76:103583. 10.1016\/j.amsu.2022.103583","journal-title":"Ann Med Surg (Lond)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1093\/omcr\/omu059","article-title":"The rising tide of bloodstream infections with Actinomyces species: bimicrobial infection with Actinomyces odontolyticus and Escherichia coli in an intravenous drug user","volume":"2014","author":"Weiand D","year":"2014","unstructured":"Weiand D, Barlow G. The rising tide of bloodstream infections with Actinomyces species: bimicrobial infection with Actinomyces odontolyticus and Escherichia coli in an intravenous drug user. Oxf Med Case Reports. 2014, 2014:156-8. 10.1093\/omcr\/omu059","journal-title":"Oxf Med Case Reports"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1590\/0037-8682-0215-2017","article-title":"Actinomycosis, a lurking threat: a report of 11 cases and literature review","volume":"51","author":"Paulo CO","year":"2018","unstructured":"Paulo CO, Jord\u00e3o S, Correia-Pinto J, Ferreira F, Neves I. Actinomycosis, a lurking threat: a report of 11 cases and literature review. Rev Soc Bras Med Trop. 2018, 51:7-13. 10.1590\/0037-8682-0215-2017","journal-title":"Rev Soc Bras Med Trop"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1258\/0956462001916047","article-title":"Actinomycosis in HIV infection: a review of a rare complication","volume":"11","author":"Chaudhry SI","year":"2000","unstructured":"Chaudhry SI, Greenspan JS. Actinomycosis in HIV infection: a review of a rare complication. Int J STD AIDS. 2000, 11:349-55. 10.1258\/0956462001916047","journal-title":"Int J STD AIDS"},{"key":"ref15","article-title":"Actinomyces and nocardia infections in immunocompromised and nonimmunocompromised patients","volume":"91","author":"Dominguez DC","year":"1999","unstructured":"Dominguez DC, Antony SJ. Actinomyces and nocardia infections in immunocompromised and nonimmunocompromised patients. J Natl Med Assoc. 1999, 91:35-9.","journal-title":"J Natl Med Assoc"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00277-002-0487-y","article-title":"Splenic actinomycotic abscess in a patient with acute myeloid leukemia","volume":"81","author":"Chen CY","year":"2002","unstructured":"Chen CY, Chen YC, Tang JL, Lin WC, Su IJ, Tien HF. Splenic actinomycotic abscess in a patient with acute myeloid leukemia. Ann Hematol. 2002, 81:532-4. 10.1007\/s00277-002-0487-y","journal-title":"Ann Hematol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/0029-7844(95)00350-9","article-title":"Intrauterine contraceptive device-associated actinomycotic abscess and Actinomyces detection on cervical smear","volume":"87","author":"Fiorino AS","year":"1996","unstructured":"Fiorino AS. Intrauterine contraceptive device-associated actinomycotic abscess and Actinomyces detection on cervical smear. Obstet Gynecol. 1996, 87:142-9. 10.1016\/0029-7844(95)00350-9","journal-title":"Obstet Gynecol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv347","article-title":"Resistance patterns in clinical isolates of pathogenic Actinomyces species","volume":"71","author":"Steininger C","year":"2016","unstructured":"Steininger C, Willinger B. Resistance patterns in clinical isolates of pathogenic Actinomyces species. J Antimicrob Chemother. 2016, 71:422-7. 10.1093\/jac\/dkv347","journal-title":"J Antimicrob Chemother"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3393\/ac.2021.00332.0047","article-title":"Perianal actinomycosis: a surgeon\u2019s perspective and review of literature","volume":"37","author":"Dosis A","year":"2021","unstructured":"Dosis A, Khan A, Leslie H, Musaad S, Smith A. Perianal actinomycosis: a surgeon\u2019s perspective and review of literature. Ann Coloproctol. 2021, 37:269-74. 10.3393\/ac.2021.00332.0047","journal-title":"Ann Coloproctol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/j.1574-6976.2011.00298.x","article-title":"Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiology","volume":"36","author":"Croxatto A","year":"2012","unstructured":"Croxatto A, Prod'hom G, Greub G. Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiology. FEMS Microbiol Rev. 2012, 36:380-407. 10.1111\/j.1574-6976.2011.00298.x","journal-title":"FEMS Microbiol Rev"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.043927-0","article-title":"The value of MALDI-TOF MS for the identification of clinically relevant anaerobic bacteria in routine laboratories","volume":"61","author":"Nagy E","year":"2012","unstructured":"Nagy E, Becker S, Kostrzewa M, Barta N, Urb\u00e1n E. The value of MALDI-TOF MS for the identification of clinically relevant anaerobic bacteria in routine laboratories. J Med Microbiol. 2012, 61:1393-400. 10.1099\/jmm.0.043927-0","journal-title":"J Med Microbiol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dki206","article-title":"Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents","volume":"56","author":"Smith AJ","year":"2005","unstructured":"Smith AJ, Hall V, Thakker B, Gemmell CG. Antimicrobial susceptibility testing of Actinomyces species with 12 antimicrobial agents. J Antimicrob Chemother. 2005, 56:407-9. 10.1093\/jac\/dki206","journal-title":"J Antimicrob Chemother"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2334-14-10","article-title":"Multivariate analysis of prognostic factors in patients with pulmonary actinomycosis","volume":"14","author":"Park JY","year":"2014","unstructured":"Park JY, Lee T, Lee H, et al.. Multivariate analysis of prognostic factors in patients with pulmonary actinomycosis. BMC Infect Dis. 2014, 14:10. 10.1186\/1471-2334-14-10","journal-title":"BMC Infect Dis"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1086\/381099","article-title":"Short-term treatment of actinomycosis: two cases and a review","volume":"38","author":"Sudhakar SS","year":"2004","unstructured":"Sudhakar SS, Ross JJ. Short-term treatment of actinomycosis: two cases and a review. Clin Infect Dis. 2004, 38:444-7. 10.1086\/381099","journal-title":"Clin Infect Dis"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/325515-actinomyces-species-as-emerging-pathogens-an-observational-study-of-clinical-infections-and-microbiological-implications","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,8]],"date-time":"2025-01-08T10:53:55Z","timestamp":1736333635000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/325515-actinomyces-species-as-emerging-pathogens-an-observational-study-of-clinical-infections-and-microbiological-implications"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,8]]},"references-count":24,"URL":"https:\/\/doi.org\/10.7759\/cureus.77128","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,8]]}}}