{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T10:42:27Z","timestamp":1791196947618,"version":"4.1.0"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,14]]},"DOI":"10.7759\/cureus.77413","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T08:57:46Z","timestamp":1736845066000},"source":"Crossref","is-referenced-by-count":5,"title":["Modulatory Effect of Probiotic Fiber (Lactobacillus reuteri) in Residual Periodontal Pockets: A Randomized, Double-Blind, Placebo-Controlled Study"],"prefix":"10.7759","author":[{"given":"Dasari","family":"Vanditha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramesh Reddy","family":"B. V.","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay Kumar","family":"Chava","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukrutha","family":"Biradavolu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreenivas","family":"Nagarakanti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sumanth","family":"Gunupati","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2012.01864.x","article-title":"Effects of a single topical doxycycline administration adjunctive to mechanical debridement in patients with persistent\/recurrent periodontitis but acceptable oral hygiene during supportive periodontal therapy","volume":"39","author":"Tonetti MS","year":"2012","unstructured":"Tonetti MS, Lang NP, Cortellini P, et al.. Effects of a single topical doxycycline administration adjunctive to mechanical debridement in patients with persistent\/recurrent periodontitis but acceptable oral hygiene during supportive periodontal therapy. J Clin Periodontol. 2012, 39:475-82. 10.1111\/j.1600-051X.2012.01864.x","journal-title":"J Clin Periodontol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.142445","article-title":"Comparative evaluation of single application of 2% whole turmeric gel versus 1% chlorhexidine gel in chronic periodontitis patients: a pilot study","volume":"18","author":"Jaswal R","year":"2014","unstructured":"Jaswal R, Dhawan S, Grover V, Malhotra R. Comparative evaluation of single application of 2% whole turmeric gel versus 1% chlorhexidine gel in chronic periodontitis patients: a pilot study. J Indian Soc Periodontol. 2014, 18:575-80. 10.4103\/0972-124X.142445","journal-title":"J Indian Soc Periodontol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2000.027001030.x","article-title":"The effect of scaling and root planing on the clinical and microbiological parameters of periodontal diseases: 12-month results","volume":"27","author":"Cugini MA","year":"2000","unstructured":"Cugini MA, Haffajee AD, Smith C, Kent RL Jr, Socransky SS. The effect of scaling and root planing on the clinical and microbiological parameters of periodontal diseases: 12-month results. J Clin Periodontol. 2000, 27:30-6. 10.1034\/j.1600-051x.2000.027001030.x","journal-title":"J Clin Periodontol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1177\/00220345920710071501","article-title":"Microbiological aspects of the chemical control of plaque and gingivitis","volume":"71","author":"Marsh PD","year":"1992","unstructured":"Marsh PD. Microbiological aspects of the chemical control of plaque and gingivitis. J Dent Res. 1992, 71:1431-8. 10.1177\/00220345920710071501","journal-title":"J Dent Res"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-302X.2005.00239.x","article-title":"Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity","volume":"20","author":"K\u00f5ll-Klais P","year":"2005","unstructured":"K\u00f5ll-Klais P, M\u00e4ndar R, Leibur E, Marcotte H, Hammarstr\u00f6m L, Mikelsaar M. Oral lactobacilli in chronic periodontitis and periodontal health: species composition and antimicrobial activity. Oral Microbiol Immunol. 2005, 20:354-61. 10.1111\/j.1399-302X.2005.00239.x","journal-title":"Oral Microbiol Immunol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00784-018-2682-9","article-title":"Are dairy products containing probiotics beneficial for oral health? A systematic review and meta-analysis","volume":"22","author":"Nadelman P","year":"2018","unstructured":"Nadelman P, Magno MB, Masterson D, da Cruz AG, Maia LC. Are dairy products containing probiotics beneficial for oral health? A systematic review and meta-analysis. Clin Oral Investig. 2018, 22:2763-85. 10.1007\/s00784-018-2682-9","journal-title":"Clin Oral Investig"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0022034515595950","article-title":"Effect of probiotic bacteria on oral Candida in frail elderly","volume":"94","author":"Kraft-Bodi E","year":"2015","unstructured":"Kraft-Bodi E, J\u00f8rgensen MR, Keller MK, Kragelund C, Twetman S. Effect of probiotic bacteria on oral Candida in frail elderly. J Dent Res. 2015, 94:181S-6S. 10.1177\/0022034515595950","journal-title":"J Dent Res"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/0972-124X.207053","article-title":"Probiotics in the treatment of periodontal disease: a systematic review","volume":"20","author":"Jayaram P","year":"2016","unstructured":"Jayaram P, Chatterjee A, Raghunathan V. Probiotics in the treatment of periodontal disease: a systematic review. J Indian Soc Periodontol. 2016, 20:488-95. 10.4103\/0972-124X.207053","journal-title":"J Indian Soc Periodontol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12155","article-title":"Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study","volume":"40","author":"Teughels W","year":"2013","unstructured":"Teughels W, Durukan A, Ozcelik O, Pauwels M, Quirynen M, Haytac MC. Clinical and microbiological effects of Lactobacillus reuteri probiotics in the treatment of chronic periodontitis: a randomized placebo-controlled study. J Clin Periodontol. 2013, 40:1025-35. 10.1111\/jcpe.12155","journal-title":"J Clin Periodontol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3402\/jom.v2i0.5344","article-title":"Effect of the probiotic Lactobacilli reuteri (Prodentis) in the management of periodontal disease: a preliminary randomized clinical trial","volume":"2","author":"Vivekananda MR","year":"2010","unstructured":"Vivekananda MR, Vandana KL, Bhat KG. Effect of the probiotic Lactobacilli reuteri (Prodentis) in the management of periodontal disease: a preliminary randomized clinical trial. J Oral Microbiol. 2010, 2:10.3402\/jom.v2i0.5344","journal-title":"J Oral Microbiol"},{"key":"ref11","article-title":"Decreased gum bleeding and reduced gingivitis by the probiotic Lactobacillus reuteri","volume":"30","author":"Krasse P","year":"2006","unstructured":"Krasse P, Carlsson B, Dahl C, Paulsson A, Nilsson A, Sinkiewicz G. Decreased gum bleeding and reduced gingivitis by the probiotic Lactobacillus reuteri. Swed Dent J. 2006, 30:55-60.","journal-title":"Swed Dent J"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6846074","article-title":"Antibiotics in the treatment of periodontitis: a systematic review of the literature","volume":"2021","author":"Hammami C","year":"2021","unstructured":"Hammami C, Nasri W. Antibiotics in the treatment of periodontitis: a systematic review of the literature. Int J Dent. 2021, 2021:6846074. 10.1155\/2021\/6846074","journal-title":"Int J Dent"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12464","article-title":"The effect of a streptococci containing probiotic in periodontal therapy: a randomized controlled trial","volume":"42","author":"Laleman I","year":"2015","unstructured":"Laleman I, Yilmaz E, Ozcelik O, et al.. The effect of a streptococci containing probiotic in periodontal therapy: a randomized controlled trial. J Clin Periodontol. 2015, 42:1032-41. 10.1111\/jcpe.12464","journal-title":"J Clin Periodontol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/jre.12608","article-title":"Probiotics alter the immune response of gingival epithelial cells challenged by Porphyromonas gingivalis","volume":"54","author":"Albuquerque-Souza E","year":"2019","unstructured":"Albuquerque-Souza E, Balzarini D, Ando-Suguimoto ES, Ishikawa KH, Simionato MR, Holzhausen M, Mayer MP. Probiotics alter the immune response of gingival epithelial cells challenged by Porphyromonas gingivalis. J Periodontal Res. 2019, 54:115-27. 10.1111\/jre.12608","journal-title":"J Periodontal Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2180-9-35","article-title":"Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors","volume":"9","author":"Jones SE","year":"2009","unstructured":"Jones SE, Versalovic J. Probiotic Lactobacillus reuteri biofilms produce antimicrobial and anti-inflammatory factors. BMC Microbiol. 2009, 9:35. 10.1186\/1471-2180-9-35","journal-title":"BMC Microbiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-33-6236-9_11","article-title":"Probiotic interventions for oral health","author":"Twetman S","year":"2021","unstructured":"Twetman S, J\u00f8rgensen MR. Probiotic interventions for oral health. Probiotic Research in Therapeutics. Pawar SV, Rishi P (ed): Springer, Singapore; 2021. 10.1007\/978-981-33-6236-9_11"},{"key":"ref17","article-title":"Probiotics in periodontal therapy","volume":"6","author":"Scariya L","year":"2015","unstructured":"Scariya L, Nagarathna DV, Varghese M. Probiotics in periodontal therapy. Int J Pharma Bio Sci. 2015, 6:242-50.","journal-title":"Int J Pharma Bio Sci"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.4103\/2279-042X.179568","article-title":"Efficacy of local use of probiotics as an adjunct to scaling and root planing in chronic periodontitis and halitosis: a randomized controlled trial","volume":"5","author":"Penala S","year":"2016","unstructured":"Penala S, Kalakonda B, Pathakota KR, et al.. Efficacy of local use of probiotics as an adjunct to scaling and root planing in chronic periodontitis and halitosis: a randomized controlled trial. J Res Pharm Pract. 2016, 5:86-93. 10.4103\/2279-042X.179568","journal-title":"J Res Pharm Pract"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2009.01434.x","article-title":"Comparison between polymerase chain reaction-based and checkerboard DNA hybridization techniques for microbial assessment of subgingival plaque samples","volume":"36","author":"Haffajee AD","year":"2009","unstructured":"Haffajee AD, Yaskell T, Torresyap G, Teles R, Socransky SS. Comparison between polymerase chain reaction-based and checkerboard DNA hybridization techniques for microbial assessment of subgingival plaque samples. J Clin Periodontol. 2009, 36:642-9. 10.1111\/j.1600-051X.2009.01434.x","journal-title":"J Clin Periodontol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/329624-modulatory-effect-of-probiotic-fiber-lactobacillus-reuteri-in-residual-periodontal-pockets-a-randomized-double-blind-placebo-controlled-study","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T08:57:47Z","timestamp":1736845067000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/329624-modulatory-effect-of-probiotic-fiber-lactobacillus-reuteri-in-residual-periodontal-pockets-a-randomized-double-blind-placebo-controlled-study"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,14]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.77413","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,14]]}}}