{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T00:11:49Z","timestamp":1773619909987,"version":"3.50.1"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,14]]},"DOI":"10.7759\/cureus.77438","type":"journal-article","created":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T17:19:49Z","timestamp":1736875189000},"source":"Crossref","is-referenced-by-count":1,"title":["Splenic Infarction in a Patient With Sickle Cell Trait Following High-Altitude Exposure"],"prefix":"10.7759","author":[{"given":"Eian G","family":"Prohl","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neel K","family":"Vaidya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7326\/M18-1161","article-title":"Clinical outcomes associated with sickle cell trait: A systematic review","volume":"169","author":"Naik RP","year":"2018","unstructured":"Naik RP, Smith-Whitley K, Hassell KL, et al.. Clinical outcomes associated with sickle cell trait: A systematic review. Ann Intern Med. 2018, 169:619-27. 10.7326\/M18-1161","journal-title":"Ann Intern Med"},{"key":"ref2","article-title":"Incidence of sickle cell trait--United States, 2010","volume":"63","author":"Ojodu J","year":"2014","unstructured":"Ojodu J, Hulihan MM, Pope SN, Grant AM. Incidence of sickle cell trait--United States, 2010. MMWR Morb Mortal Wkly Rep. 2014, 63:1155-8.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1053\/j.semperi.2009.12.006","article-title":"History and current status of newborn screening for hemoglobinopathies","volume":"34","author":"Benson JM","year":"2010","unstructured":"Benson JM, Therrell BL Jr. History and current status of newborn screening for hemoglobinopathies. Semin Perinatol. 2010, 34:134-44. 10.1053\/j.semperi.2009.12.006","journal-title":"Semin Perinatol"},{"key":"ref4","article-title":"Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait","volume":"98","author":"Treadwell MJ","year":"2006","unstructured":"Treadwell MJ, McClough L, Vichinsky E. Using qualitative and quantitative strategies to evaluate knowledge and perceptions about sickle cell disease and sickle cell trait. J Natl Med Assoc. 2006, 98:704-10.","journal-title":"J Natl Med Assoc"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177\/0193945916665089","article-title":"Knowledge and awareness of sickle cell trait among young African American adults","volume":"39","author":"Harrison SE","year":"2017","unstructured":"Harrison SE, Walcott CM, Warner TD. Knowledge and awareness of sickle cell trait among young African American adults. West J Nurs Res. 2017, 39:1222-39. 10.1177\/0193945916665089","journal-title":"West J Nurs Res"},{"key":"ref6","article-title":"Sickle cell trait","author":"Vichinsky EP","year":"2023","unstructured":"Vichinsky EP. Sickle cell trait. UpToDate. Post TW (ed): UpToDate, Waltham, MA; 2023."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2013.05.009","article-title":"Acute splenic syndrome in an African-American male with sickle cell trait on a commercial airplane flight","volume":"45","author":"Murano T","year":"2013","unstructured":"Murano T, Fox AD, Anjaria D. Acute splenic syndrome in an African-American male with sickle cell trait on a commercial airplane flight. J Emerg Med. 2013, 45:e161-5. 10.1016\/j.jemermed.2013.05.009","journal-title":"J Emerg Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1954.02940360009003","article-title":"Clinical triad of massive splenic infarction, sicklemia trait, and high altitude flying","volume":"154","author":"Cooley JC","year":"1954","unstructured":"Cooley JC, Peterson WL, Engel CE, Jernigan JP. Clinical triad of massive splenic infarction, sicklemia trait, and high altitude flying. J Am Med Assoc. 1954, 154:111-3. 10.1001\/jama.1954.02940360009003","journal-title":"J Am Med Assoc"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-32-2-338","article-title":"Danger of airplane flight to persons with sicklemia","volume":"32","author":"Sullivan BH Jr","year":"1950","unstructured":"Sullivan BH Jr. Danger of airplane flight to persons with sicklemia. Ann Intern Med. 1950, 32:338-42. 10.7326\/0003-4819-32-2-338","journal-title":"Ann Intern Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.9815","article-title":"Splenic infarct secondary to high altitude exposure in sickle cell trait patients: a case series","volume":"12","author":"Gonzalez L","year":"2020","unstructured":"Gonzalez L, Shapiro AF, Tafur A, Plaza-Meneses C, Sabando B. Splenic infarct secondary to high altitude exposure in sickle cell trait patients: a case series. Cureus. 2020, 12:e9815. 10.7759\/cureus.9815","journal-title":"Cureus"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM197210052871413","article-title":"Splenic infarct and sickle-(cell) trait","volume":"287","author":"O'Brien RT","year":"1972","unstructured":"O'Brien RT, Pearson HA, Godley JA, Spencer RP. Splenic infarct and sickle-(cell) trait. N Engl J Med. 1972, 287:720. 10.1056\/NEJM197210052871413","journal-title":"N Engl J Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.wem.2017.08.021","article-title":"A case of autosplenectomy in sickle cell trait following an exposure to high altitude","volume":"29","author":"Yanamandra U","year":"2018","unstructured":"Yanamandra U, Das R, Malhotra P, Varma S. A case of autosplenectomy in sickle cell trait following an exposure to high altitude. Wilderness Environ Med. 2018, 29:85-9. 10.1016\/j.wem.2017.08.021","journal-title":"Wilderness Environ Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2012.05.033","article-title":"Splenic infarction at high altitude secondary to sickle cell trait","volume":"31","author":"Scordino D","year":"2013","unstructured":"Scordino D, Kirsch T. Splenic infarction at high altitude secondary to sickle cell trait. Am J Emerg Med. 2013, 31:446.e1-3. 10.1016\/j.ajem.2012.05.033","journal-title":"Am J Emerg Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1089\/ham.2014.1034","article-title":"The splenic syndrome in individuals with sickle cell trait","volume":"15","author":"Goodman J","year":"2014","unstructured":"Goodman J, Hassell K, Irwin D, Witkowski EH, Nuss R. The splenic syndrome in individuals with sickle cell trait. High Alt Med Biol. 2014, 15:468-71. 10.1089\/ham.2014.1034","journal-title":"High Alt Med Biol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.7205\/milmed.173.12.1233","article-title":"Splenic syndrome: a rare indication for splenectomy","volume":"173","author":"Pothula V","year":"2008","unstructured":"Pothula V, Saegusa E, Takekoshi D, Edson T, Ignacio R. Splenic syndrome: a rare indication for splenectomy. Mil Med. 2008, 173:1233-7. 10.7205\/milmed.173.12.1233","journal-title":"Mil Med"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1985.03350390093033","article-title":"Splenic syndrome at mountain altitudes in sickle cell trait. Its occurrence in nonblack persons","volume":"253","author":"Lane PA","year":"1985","unstructured":"Lane PA, Githens JH. Splenic syndrome at mountain altitudes in sickle cell trait. Its occurrence in nonblack persons. JAMA. 1985, 253:2251-4. 10.1001\/jama.1985.03350390093033","journal-title":"JAMA"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1002\/jha2.248","article-title":"Splenic infarction in sickle cell trait: A comprehensive systematic review of case studies","volume":"2","author":"Jefferson JM","year":"2021","unstructured":"Jefferson JM, Sims WM, Umeh N, et al.. Splenic infarction in sickle cell trait: A comprehensive systematic review of case studies. EJHaem. 2021, 2:585-600. 10.1002\/jha2.248","journal-title":"EJHaem"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-016-0786-8","article-title":"Massive splenic infarction and splenic venous thrombosis observed in a patient with acute splenic syndrome of sickle cell traits on contrast-enhanced thin-slice computed tomography","volume":"41","author":"Hayashi TY","year":"2016","unstructured":"Hayashi TY, Matsuda I, Hagiwara K, Takayanagi T, Hagiwara A. Massive splenic infarction and splenic venous thrombosis observed in a patient with acute splenic syndrome of sickle cell traits on contrast-enhanced thin-slice computed tomography. Abdom Radiol (NY). 2016, 41:1718-21. 10.1007\/s00261-016-0786-8","journal-title":"Abdom Radiol (NY)"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2008.02.014","article-title":"Splenic infarction: 10 years of experience","volume":"27","author":"Antopolsky M","year":"2009","unstructured":"Antopolsky M, Hiller N, Salameh S, Goldshtein B, Stalnikowicz R. Splenic infarction: 10 years of experience. Am J Emerg Med. 2009, 27:262-5. 10.1016\/j.ajem.2008.02.014","journal-title":"Am J Emerg Med"},{"key":"ref20","article-title":"Splenic syndrome in patients at high altitude with unrecognized sickle cell trait: splenectomy is often unnecessary","volume":"48","author":"Sheikha A","year":"2005","unstructured":"Sheikha A. Splenic syndrome in patients at high altitude with unrecognized sickle cell trait: splenectomy is often unnecessary. Can J Surg. 2005, 48:377-81.","journal-title":"Can J Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/326638-splenic-infarction-in-a-patient-with-sickle-cell-trait-following-high-altitude-exposure","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,14]],"date-time":"2025-01-14T17:19:51Z","timestamp":1736875191000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/326638-splenic-infarction-in-a-patient-with-sickle-cell-trait-following-high-altitude-exposure"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,14]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.77438","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,14]]}}}