{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T04:40:19Z","timestamp":1737434419448,"version":"3.33.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,1,20]]},"DOI":"10.7759\/cureus.77743","type":"journal-article","created":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T04:12:42Z","timestamp":1737432762000},"source":"Crossref","is-referenced-by-count":0,"title":["Palliative Radiotherapy to Preserve Eyesight in a Recurrent, Difficult-to-Treat Basal Cell Carcinoma"],"prefix":"10.7759","author":[{"given":"Andra Ioana","family":"Copil\u0103u","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beatrice","family":"B\u0103l\u0103ceanu-Gur\u0103u","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrei","family":"Anghel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Irina","family":"Tudose","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mara M\u0103d\u0103lina","family":"Mihai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2023.113254","article-title":"European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023","volume":"192","author":"Peris K","year":"2023","unstructured":"Peris K, Fargnoli MC, Kaufmann R, et al.. European consensus-based interdisciplinary guideline for diagnosis and treatment of basal cell carcinoma-update 2023. Eur J Cancer. 2023, 192:113254. 10.1016\/j.ejca.2023.113254","journal-title":"Eur J Cancer"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2018.03.060","article-title":"Basal cell carcinoma: epidemiology; pathophysiology; clinical and histological subtypes; and disease associations","volume":"80","author":"Cameron MC","year":"2019","unstructured":"Cameron MC, Lee E, Hibler BP, et al.. Basal cell carcinoma: epidemiology; pathophysiology; clinical and histological subtypes; and disease associations. J Am Acad Dermatol. 2019, 80:303-17. 10.1016\/j.jaad.2018.03.060","journal-title":"J Am Acad Dermatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.2340\/00015555-3495","article-title":"Update in the management of basal cell carcinoma","volume":"100","author":"Basset-Seguin N","year":"2020","unstructured":"Basset-Seguin N, Herms F. Update in the management of basal cell carcinoma. Acta Derm Venereol. 2020, 100:adv00140. 10.2340\/00015555-3495","journal-title":"Acta Derm Venereol"},{"key":"ref4","article-title":"Approach to management of giant basal cell carcinomas","volume":"99","author":"Mott SE","year":"2017","unstructured":"Mott SE, Hunter WJ, Silva E, Huerter CJ. Approach to management of giant basal cell carcinomas. Cutis. 2017, 99:356-62.","journal-title":"Cutis"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17466","article-title":"Position statement on classification of basal cell carcinomas. Part 1: unsupervised clustering of experts as a way to build an operational classification of advanced basal cell carcinoma based on pattern recognition","volume":"35","author":"Grob JJ","year":"2021","unstructured":"Grob JJ, Guminski A, Malvehy J, et al.. Position statement on classification of basal cell carcinomas. Part 1: unsupervised clustering of experts as a way to build an operational classification of advanced basal cell carcinoma based on pattern recognition. J Eur Acad Dermatol Venereol. 2021, 35:1949-56. 10.1111\/jdv.17466","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.17467","article-title":"Position statement on classification of basal cell carcinomas. Part 2: EADO proposal for new operational staging system adapted to basal cell carcinomas","volume":"35","author":"Grob JJ","year":"2021","unstructured":"Grob JJ, Gaudy-Marqueste C, Guminski A, et al.. Position statement on classification of basal cell carcinomas. Part 2: EADO proposal for new operational staging system adapted to basal cell carcinomas. J Eur Acad Dermatol Venereol. 2021, 35:2149-53. 10.1111\/jdv.17467","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2023.0056","article-title":"Basal Cell Skin Cancer, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology","volume":"21","author":"Schmults CD","year":"2023","unstructured":"Schmults CD, Blitzblau R, Aasi SZ, et al.. Basal Cell Skin Cancer, Version 2.2024, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2023, 21:1181-203. 10.6004\/jnccn.2023.0056","journal-title":"J Natl Compr Canc Netw"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.2147\/DDDT.S325852","article-title":"Current perspectives in the treatment of locally advanced basal cell carcinoma","volume":"16","author":"Gupta N","year":"2022","unstructured":"Gupta N, Ruiz ES. Current perspectives in the treatment of locally advanced basal cell carcinoma. Drug Des Devel Ther. 2022, 16:183-90. 10.2147\/DDDT.S325852","journal-title":"Drug Des Devel Ther"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1055\/s-0040-1709119","article-title":"Radiotherapy in cutaneous squamous cell and basal cell carcinoma","volume":"36","author":"Gharzai LA","year":"2020","unstructured":"Gharzai LA, Mierzwa ML. Radiotherapy in cutaneous squamous cell and basal cell carcinoma. Facial Plast Surg. 2020, 36:180-5. 10.1055\/s-0040-1709119","journal-title":"Facial Plast Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jgo.2018.09.009","article-title":"The role of personalized interventional radiotherapy (brachytherapy) in the management of older patients with non-melanoma skin cancer","volume":"10","author":"Lancellotta V","year":"2019","unstructured":"Lancellotta V, Kov\u00e1cs G, Tagliaferri L, et al.. The role of personalized interventional radiotherapy (brachytherapy) in the management of older patients with non-melanoma skin cancer. J Geriatr Oncol. 2019, 10:514-7. 10.1016\/j.jgo.2018.09.009","journal-title":"J Geriatr Oncol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/onco.13959","article-title":"Hedgehog inhibitor induction with addition of concurrent superficial radiotherapy in patients with locally advanced basal cell carcinoma: a case series","volume":"26","author":"Weissman JP","year":"2021","unstructured":"Weissman JP, Samlowski W, Meoz R. Hedgehog inhibitor induction with addition of concurrent superficial radiotherapy in patients with locally advanced basal cell carcinoma: a case series. Oncologist. 2021, 26:e2247-53. 10.1002\/onco.13959","journal-title":"Oncologist"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2017.08.011","article-title":"Hypofractionated radiation therapy for basal and squamous cell skin cancer: a meta-analysis","volume":"125","author":"Zaorsky NG","year":"2017","unstructured":"Zaorsky NG, Lee CT, Zhang E, Keith SW, Galloway TJ. Hypofractionated radiation therapy for basal and squamous cell skin cancer: a meta-analysis. Radiother Oncol. 2017, 125:13-20. 10.1016\/j.radonc.2017.08.011","journal-title":"Radiother Oncol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.7326\/M18-0678","article-title":"Treatments of primary basal cell carcinoma of the skin: a systematic review and network meta-analysis","volume":"169","author":"Drucker AM","year":"2018","unstructured":"Drucker AM, Adam GP, Rofeberg V, et al.. Treatments of primary basal cell carcinoma of the skin: a systematic review and network meta-analysis. Ann Intern Med. 2018, 169:456-66. 10.7326\/M18-0678","journal-title":"Ann Intern Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16230","article-title":"Sonidegib and vismodegib in the treatment of patients with locally advanced basal cell carcinoma: a joint expert opinion","volume":"34","author":"Dummer R","year":"2020","unstructured":"Dummer R, Ascierto PA, Basset-Seguin N, et al.. Sonidegib and vismodegib in the treatment of patients with locally advanced basal cell carcinoma: a joint expert opinion. J Eur Acad Dermatol Venereol. 2020, 34:1944-56. 10.1111\/jdv.16230","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s40257-023-00763-x","article-title":"Efficacy and safety of Sonic hedgehog inhibitors in basal cell carcinomas: an updated systematic review and meta-analysis (2009-2022)","volume":"24","author":"Nguyen A","year":"2023","unstructured":"Nguyen A, Xie P, Litvinov IV, Lefran\u00e7ois P. Efficacy and safety of Sonic hedgehog inhibitors in basal cell carcinomas: an updated systematic review and meta-analysis (2009-2022). Am J Clin Dermatol. 2023, 24:359-74. 10.1007\/s40257-023-00763-x","journal-title":"Am J Clin Dermatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(14)71523-5","article-title":"Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid","volume":"113","author":"Howard GR","year":"1992","unstructured":"Howard GR, Nerad JA, Carter KD, Whitaker DC. Clinical characteristics associated with orbital invasion of cutaneous basal cell and squamous cell tumors of the eyelid. Am J Ophthalmol. 1992, 113:123-33. 10.1016\/s0002-9394(14)71523-5","journal-title":"Am J Ophthalmol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4081\/oncol.2020.420","article-title":"Periocular basal cell carcinoma - clinical perspectives","volume":"14","author":"Furdova A","year":"2020","unstructured":"Furdova A, Kapitanova K, Kollarova A, Sekac J. Periocular basal cell carcinoma - clinical perspectives. Oncol Rev. 2020, 14:420. 10.4081\/oncol.2020.420","journal-title":"Oncol Rev"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/4347707","article-title":"Advanced periocular basal cell carcinoma with orbital invasion: update on management and treatment advances","volume":"2024","author":"Bengoa-Gonz\u00e1lez A","year":"2024","unstructured":"Bengoa-Gonz\u00e1lez A, Menc\u00eda-Guti\u00e9rrez E, Garrido M, Salvador E, Lago-Llin\u00e1s MD. Advanced periocular basal cell carcinoma with orbital invasion: update on management and treatment advances. J Ophthalmol. 2024, 2024:4347707. 10.1155\/2024\/4347707","journal-title":"J Ophthalmol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2004.11.036","article-title":"Orbital invasion by periocular basal cell carcinoma","volume":"112","author":"Leibovitch I","year":"2005","unstructured":"Leibovitch I, McNab A, Sullivan T, Davis G, Selva D. Orbital invasion by periocular basal cell carcinoma. Ophthalmology. 2005, 112:717-23. 10.1016\/j.ophtha.2004.11.036","journal-title":"Ophthalmology"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13225706","article-title":"Treatment of advanced basal cell carcinoma with hedgehog pathway inhibitors: a multidisciplinary expert meeting","volume":"13","author":"De Giorgi V","year":"2021","unstructured":"De Giorgi V, Scarf\u00ec F, Trane L, et al.. Treatment of advanced basal cell carcinoma with hedgehog pathway inhibitors: a multidisciplinary expert meeting. Cancers (Basel). 2021, 13:10.3390\/cancers13225706","journal-title":"Cancers (Basel)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/320332-palliative-radiotherapy-to-preserve-eyesight-in-a-recurrent-difficult-to-treat-basal-cell-carcinoma","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,21]],"date-time":"2025-01-21T04:12:46Z","timestamp":1737432766000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/320332-palliative-radiotherapy-to-preserve-eyesight-in-a-recurrent-difficult-to-treat-basal-cell-carcinoma"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,1,20]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.77743","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,1,20]]}}}