{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,12]],"date-time":"2026-05-12T01:24:50Z","timestamp":1778549090402,"version":"3.51.4"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,14]]},"DOI":"10.7759\/cureus.78980","type":"journal-article","created":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T10:03:51Z","timestamp":1739527431000},"source":"Crossref","is-referenced-by-count":1,"title":["\"If We Manage Early, We Can Get It Right\": A Descriptive Study of Healthcare Workers' Experiences Managing Sepsis at a Kenyan Referral Hospital"],"prefix":"10.7759","author":[{"given":"Maria","family":"Srour","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shamim","family":"Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Matthew","family":"Hodge","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Charles","family":"Kwobah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Megan","family":"McHenry","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Ann","family":"Etling","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amira","family":"Nafiseh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Babar","family":"Khan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Clare C","family":"Prohaska","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Neelima","family":"Navuluri","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)32989-7","article-title":"Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study","volume":"395","author":"Rudd KE","year":"2020","unstructured":"Rudd KE, Johnson SC, Agesa KM, et al.. Global, regional, and national sepsis incidence and mortality, 1990-2017: analysis for the Global Burden of Disease Study. Lancet. 2020, 395:200-11. 10.1016\/S0140-6736(19)32989-7","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-018-2157-z","article-title":"The global burden of sepsis: barriers and potential solutions","volume":"22","author":"Rudd KE","year":"2018","unstructured":"Rudd KE, Kissoon N, Limmathurotsakul D, et al.. The global burden of sepsis: barriers and potential solutions. Crit Care. 2018, 22:232. 10.1186\/s13054-018-2157-z","journal-title":"Crit Care"},{"key":"ref3","unstructured":"Kampala declaration. (2017). Accessed. February 10, 2025: https:\/\/www.africansepsisalliance.org\/kampaladeclaration#:~:text=The%20African%20Sepsis%20Alliance%20aims,millions%20...."},{"key":"ref4","unstructured":"Global report on the epidemiology and burden of sepsis. (2020). Accessed. February 10, 2025: https:\/\/www.who.int\/publications\/i\/item\/9789240010789."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1101549","article-title":"Mortality after fluid bolus in African children with severe infection","volume":"364","author":"Maitland K","year":"2011","unstructured":"Maitland K, Kiguli S, Opoka RO, et al.. Mortality after fluid bolus in African children with severe infection. N Engl J Med. 2011, 364:2483-95. 10.1056\/NEJMoa1101549","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2017.10913","article-title":"Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial","volume":"318","author":"Andrews B","year":"2017","unstructured":"Andrews B, Semler MW, Muchemwa L, et al.. Effect of an early resuscitation protocol on in-hospital mortality among adults with sepsis and hypotension: a randomized clinical trial. JAMA. 2017, 318:1233-40. 10.1001\/jama.2017.10913","journal-title":"JAMA"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0029858","article-title":"Feasibility of modified surviving sepsis campaign guidelines in a resource-restricted setting based on a cohort study of severe S. aureus sepsis","volume":"7","author":"Mahavanakul W","year":"2012","unstructured":"Mahavanakul W, Nickerson EK, Srisomang P, et al.. Feasibility of modified surviving sepsis campaign guidelines in a resource-restricted setting based on a cohort study of severe S. aureus sepsis. PLoS One. 2012, 7:e29858. 10.1371\/journal.pone.0029858","journal-title":"PLoS One"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph15092017","article-title":"The early recognition and management of sepsis in sub-Saharan African adults: a systematic review and meta-analysis","volume":"15","author":"Morton B","year":"2018","unstructured":"Morton B, Stolbrink M, Kagima W, Rylance J, Mortimer K. The early recognition and management of sepsis in sub-Saharan African adults: a systematic review and meta-analysis. Int J Environ Res Public Health. 2018, 15:2017. 10.3390\/ijerph15092017","journal-title":"Int J Environ Res Public Health"},{"key":"ref9","article-title":"Ecological models of health behavior","author":"Sallis JF","year":"2008","unstructured":"Sallis JF, Owen N, Fisher EB. Ecological models of health behavior. Health Behavior and Health Education: Theory, Research, and Practice. Glanz K, Rimer BK, Viswanath K (ed): Jossey-Bass, San Francisco, CA; 2008."},{"key":"ref10","article-title":"IU Center for Global Health, and The Indiana University School of Medicine: Mapping Contributions and Connections: The UN's Sustainable Development Goals (SDGs) and IUPUI","year":"2021","unstructured":"Mapping contributions & connections. the UN's Sustainable Development Goals (SDGs) and IUPUI. Indiana University Indianapolis, Indianapolis, IN; 2021. https:\/\/international.indianapolis.iu.edu\/doc\/partnerships\/AMPATH-SDGs-report_2021.pdf."},{"key":"ref11","unstructured":"Kenya Household and Health Expenditure and Utilization Survey (KHHEUS) 2018. (2018). Accessed. February 10, 2025: https:\/\/statistics.knbs.or.ke\/nada\/index.php\/catalog\/95."},{"key":"ref12","unstructured":"SHIF. Cure for ailing healthcare system or a repeat of past mistakes?. (2024). Accessed: February 10, 2025: https:\/\/nation.africa\/kenya\/health\/shif-cure-for-ailing-heathcare-system-or-a-repeat-of-past-mistakes--4786224."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/2050312118822927","article-title":"Grounded theory research: a design framework for novice researchers","volume":"7","author":"Chun Tie Y","year":"2019","unstructured":"Chun Tie Y, Birks M, Francis K. Grounded theory research: a design framework for novice researchers. SAGE Open Med. 2019, 7:2050312118822927. 10.1177\/2050312118822927","journal-title":"SAGE Open Med"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-018-2125-7","article-title":"Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials","volume":"22","author":"Wirz Y","year":"2018","unstructured":"Wirz Y, Meier MA, Bouadma L, et al.. Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in intensive care unit patients with infection and sepsis patients: a patient-level meta-analysis of randomized trials. Crit Care. 2018, 22:191. 10.1186\/s13054-018-2125-7","journal-title":"Crit Care"},{"key":"ref15","unstructured":"Kenya Universal Health Coverage (UHC) Policy 2020-2030. (2020). Accessed. February 10, 2025: http:\/\/guidelines.health.go.ke:8000\/media\/Kenya_Universal_Health_Coverage_Policy_2020__2030.pdf."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080\/23288604.2018.1513267","article-title":"Kenya National Hospital Insurance Fund reforms: implications and lessons for universal health coverage","volume":"4","author":"Barasa E","year":"2018","unstructured":"Barasa E, Rogo K, Mwaura N, Chuma J. Kenya National Hospital Insurance Fund reforms: implications and lessons for universal health coverage. Health Syst Reform. 2018, 4:346-61. 10.1080\/23288604.2018.1513267","journal-title":"Health Syst Reform"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1186\/s12939-024-02171-x","article-title":"Examining inequalities in spatial access to national health insurance fund contracted facilities in Kenya","volume":"23","author":"Kazungu J","year":"2024","unstructured":"Kazungu J, Moturi AK, Kuhora S, Ouko J, Quaife M, Nonvignon J, Barasa E. Examining inequalities in spatial access to national health insurance fund contracted facilities in Kenya. Int J Equity Health. 2024, 23:78. 10.1186\/s12939-024-02171-x","journal-title":"Int J Equity Health"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1186\/s12913-024-11282-8","article-title":"Barriers of access to primary healthcare services by National Health Insurance Fund capitated members in Uasin Gishu County, Kenya","volume":"24","author":"Were BN","year":"2024","unstructured":"Were BN, Mwangi EM, Muiruri LW. Barriers of access to primary healthcare services by National Health Insurance Fund capitated members in Uasin Gishu County, Kenya. BMC Health Serv Res. 2024, 24:1025. 10.1186\/s12913-024-11282-8","journal-title":"BMC Health Serv Res"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgh-2022-009748","article-title":"Investing in the health workforce in Kenya: trends in size, composition and distribution from a descriptive health labour market analysis","volume":"7","author":"Okoroafor SC","year":"2022","unstructured":"Okoroafor SC, Kwesiga B, Ogato J, et al.. Investing in the health workforce in Kenya: trends in size, composition and distribution from a descriptive health labour market analysis. BMJ Glob Health. 2022, 7:e009748. 10.1136\/bmjgh-2022-009748","journal-title":"BMJ Glob Health"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/1472-6963-6-89","article-title":"The cost of health professionals' brain drain in Kenya","volume":"6","author":"Kirigia JM","year":"2006","unstructured":"Kirigia JM, Gbary AR, Muthuri LK, Nyoni J, Seddoh A. The cost of health professionals' brain drain in Kenya. BMC Health Serv Res. 2006, 6:89. 10.1186\/1472-6963-6-89","journal-title":"BMC Health Serv Res"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.5334\/aogh.2568","article-title":"Emergency department design in low- and middle-income settings: lessons from a university hospital in Haiti","volume":"86","author":"Marsh RH","year":"2020","unstructured":"Marsh RH, Chalmers KD, Checkett KA, et al.. Emergency department design in low- and middle-income settings: lessons from a university hospital in Haiti. Ann Glob Health. 2020, 86:6. 10.5334\/aogh.2568","journal-title":"Ann Glob Health"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/s12960-017-0248-6","article-title":"Bridging the human resource gap in surgical and anesthesia care in low-resource countries: a review of the task sharing literature","volume":"15","author":"Ashengo T","year":"2017","unstructured":"Ashengo T, Skeels A, Hurwitz EJ, Thuo E, Sanghvi H. Bridging the human resource gap in surgical and anesthesia care in low-resource countries: a review of the task sharing literature. Hum Resour Health. 2017, 15:77. 10.1186\/s12960-017-0248-6","journal-title":"Hum Resour Health"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0236308","article-title":"Assessing the hospital surge capacity of the Kenyan health system in the face of the COVID-19 pandemic","volume":"15","author":"Barasa EW","year":"2020","unstructured":"Barasa EW, Ouma PO, Okiro EA. Assessing the hospital surge capacity of the Kenyan health system in the face of the COVID-19 pandemic. PLoS One. 2020, 15:e0236308. 10.1371\/journal.pone.0236308","journal-title":"PLoS One"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0284245","article-title":"Organisation, staffing and resources of critical care units in Kenya","volume":"18","author":"Mwangi W","year":"2023","unstructured":"Mwangi W, Kaddu R, Njoki Muiru C, et al.. Organisation, staffing and resources of critical care units in Kenya. PLoS One. 2023, 18:e0284245. 10.1371\/journal.pone.0284245","journal-title":"PLoS One"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.34197\/ats-scholar.2020-0060PS","article-title":"COVID-19 and the need for global critical care training. Why ventilators alone are not the answer","volume":"2","author":"Brotherton BJ","year":"2020","unstructured":"Brotherton BJ, Mbugua E, Halestrap P, Lee BW. COVID-19 and the need for global critical care training. Why ventilators alone are not the answer. ATS Sch. 2020, 2:13-8. 10.34197\/ats-scholar.2020-0060PS","journal-title":"ATS Sch"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/j.afjem.2023.08.006","article-title":"Development and delivery of a higher diploma in emergency medicine and critical care for clinical officers in Kenya","volume":"13","author":"Halestrap P","year":"2023","unstructured":"Halestrap P, Aliba D, Otieno G, et al.. Development and delivery of a higher diploma in emergency medicine and critical care for clinical officers in Kenya. Afr J Emerg Med. 2023, 13:225-9. 10.1016\/j.afjem.2023.08.006","journal-title":"Afr J Emerg Med"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)30459-8","article-title":"Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions","volume":"391","author":"Sayed S","year":"2018","unstructured":"Sayed S, Cherniak W, Lawler M, et al.. Improving pathology and laboratory medicine in low-income and middle-income countries: roadmap to solutions. Lancet. 2018, 391:1939-52. 10.1016\/S0140-6736(18)30459-8","journal-title":"Lancet"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097\/pq9.0000000000000053","article-title":"Reducing interdisciplinary communication failures through secure text messaging: a quality improvement project","volume":"3","author":"Hansen JE","year":"2018","unstructured":"Hansen JE, Lazow M, Hagedorn PA. Reducing interdisciplinary communication failures through secure text messaging: a quality improvement project. Pediatr Qual Saf. 2018, 3:e053. 10.1097\/pq9.0000000000000053","journal-title":"Pediatr Qual Saf"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.k4907","article-title":"Understanding organisational culture for healthcare quality improvement","volume":"363","author":"Mannion R","year":"2018","unstructured":"Mannion R, Davies H. Understanding organisational culture for healthcare quality improvement. BMJ. 2018, 363:k4907. 10.1136\/bmj.k4907","journal-title":"BMJ"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/321842-if-we-manage-early-we-can-get-it-right-a-descriptive-study-of-healthcare-workers-experiences-managing-sepsis-at-a-kenyan-referral-hospital","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,14]],"date-time":"2025-02-14T10:03:56Z","timestamp":1739527436000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/321842-if-we-manage-early-we-can-get-it-right-a-descriptive-study-of-healthcare-workers-experiences-managing-sepsis-at-a-kenyan-referral-hospital"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,14]]},"references-count":29,"URL":"https:\/\/doi.org\/10.7759\/cureus.78980","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,14]]}}}