{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T05:13:30Z","timestamp":1740374010209,"version":"3.37.3"},"reference-count":33,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,22]]},"DOI":"10.7759\/cureus.79485","type":"journal-article","created":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T06:48:56Z","timestamp":1740293336000},"source":"Crossref","is-referenced-by-count":0,"title":["Evaluation of Etiological Causes and Incidence of Pancytopenia: A Case Series from a Tertiary Care Center"],"prefix":"10.7759","author":[{"given":"\u0130lker","family":"\u00c7ordan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tufan","family":"Tukek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.73148","article-title":"A comprehensive analysis of clinical presentations, laboratory findings, and etiologies of pancytopenia: a tertiary care experience","volume":"16","author":"Fazal W","year":"2024","unstructured":"Fazal W, Khan S, Akhtar R, et al.. A comprehensive analysis of clinical presentations, laboratory findings, and etiologies of pancytopenia: a tertiary care experience. Cureus. 2024, 16:10.7759\/cureus.73148","journal-title":"Cureus"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2727.78555","article-title":"Pancytopenia: a clinico hematological study","volume":"3","author":"Gayathri BN","year":"2011","unstructured":"Gayathri BN, Rao KS. Pancytopenia: a clinico hematological study. J Lab Physicians. 2011, 3:15-20. 10.4103\/0974-2727.78555","journal-title":"J Lab Physicians"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1186\/2052-1839-13-10","article-title":"An etiological reappraisal of pancytopenia - largest series reported to date from a single tertiary care teaching hospital","volume":"13","author":"Jain A","year":"2013","unstructured":"Jain A, Naniwadekar M. An etiological reappraisal of pancytopenia - largest series reported to date from a single tertiary care teaching hospital. BMC Hematol. 2013, 13:10.1186\/2052-1839-13-10","journal-title":"BMC Hematol"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.67875","article-title":"Investigating the clinico-etiological profile of pediatric pancytopenia: a prospective study in a tertiary care center","volume":"16","author":"Nadig ND","year":"2024","unstructured":"Nadig ND, Rajan P, Kolahalam VS, et al.. Investigating the clinico-etiological profile of pediatric pancytopenia: a prospective study in a tertiary care center. Cureus. 2024, 16:10.7759\/cureus.67875","journal-title":"Cureus"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.blre.2018.03.001","article-title":"Approach to pancytopenia: diagnostic algorithm for clinical hematologists","volume":"32","author":"Gnanaraj J","year":"2018","unstructured":"Gnanaraj J, Parnes A, Francis CW, Go RS, Takemoto CM, Hashmi SK. Approach to pancytopenia: diagnostic algorithm for clinical hematologists. Blood Rev. 2018, 32:361-7. 10.1016\/j.blre.2018.03.001","journal-title":"Blood Rev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinme.2024.100235","article-title":"Approach to pancytopenia: from blood tests to the bedside","volume":"24","author":"Chew S","year":"2024","unstructured":"Chew S, Kamangar M. Approach to pancytopenia: from blood tests to the bedside. Clin Med (Lond). 2024, 24:10.1016\/j.clinme.2024.100235","journal-title":"Clin Med (Lond)"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1177\/0379572117697535","article-title":"Perturbing status of vitamin B12 in Indian infants and their mothers","volume":"38","author":"Mittal M","year":"2017","unstructured":"Mittal M, Bansal V, Jain R, Dabla PK. Perturbing status of vitamin B12 in Indian infants and their mothers. Food Nutr Bull. 2017, 38:209-15. 10.1177\/0379572117697535","journal-title":"Food Nutr Bull"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3949\/ccjm.87a.19072","article-title":"Severe megaloblastic anemia: vitamin deficiency and other causes","volume":"87","author":"Socha DS","year":"2020","unstructured":"Socha DS, DeSouza SI, Flagg A, Sekeres M, Rogers HJ. Severe megaloblastic anemia: vitamin deficiency and other causes. Cleve Clin J Med. 2020, 87:153-64. 10.3949\/ccjm.87a.19072","journal-title":"Cleve Clin J Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.52764\/jms.23.31.1.12","article-title":"Frequency of pancytopenia among patients with vitamin B12 deficiency","volume":"31","author":"Niazi HT","year":"2023","unstructured":"Niazi HT, Jan ZS, Jan NS, Bahadur L, Khan KA, Ali M. Frequency of pancytopenia among patients with vitamin B12 deficiency. J Med Sci. 2023, 31:62-6. 10.52764\/jms.23.31.1.12","journal-title":"J Med Sci"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.4103\/2231-0770.191447","article-title":"Etiological causes of pancytopenia: a report of 137 cases","volume":"6","author":"Yoku\u015f O","year":"2016","unstructured":"Yoku\u015f O, Gedik H. Etiological causes of pancytopenia: a report of 137 cases. Avicenna J Med. 2016, 6:109-12. 10.4103\/2231-0770.191447","journal-title":"Avicenna J Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.21601\/ortadogutipdergisi.570341","article-title":"Etiological evaluation in 766 patients with pancytopenia; a single center experience","volume":"12","author":"Erismis B","year":"2020","unstructured":"Erismis B, Gulcicek G, Sisman M, Ozturk BY, Yilmaz D, Demiriz IS. Etiological evaluation in 766 patients with pancytopenia; a single center experience. Ortadogu T\u0131p Derg. 2020, 12:165-9. 10.21601\/ortadogutipdergisi.570341","journal-title":"Ortadogu T\u0131p Derg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/nu5114521","article-title":"Cobalamin deficiency: clinical picture and radiological findings","volume":"5","author":"Briani C","year":"2013","unstructured":"Briani C, Torre CD, Citton V, Manara R, Pompanin S, Binotto G, Adami F. Cobalamin deficiency: clinical picture and radiological findings. Nutrients. 2013, 5:4521-39. 10.3390\/nu5114521","journal-title":"Nutrients"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.5152\/tjg.2024.23572","article-title":"Changing trends in the etiology of cirrhosis in T\u00fcrkiye: a multicenter nationwide study","volume":"35","author":"\u00dc\u00e7bilek E","year":"2024","unstructured":"\u00dc\u00e7bilek E, Y\u0131ld\u0131r\u0131m AE, Ellik Z, et al.. Changing trends in the etiology of cirrhosis in T\u00fcrkiye: a multicenter nationwide study. Turk J Gastroenterol. 2024, 35:772-7. 10.5152\/tjg.2024.23572","journal-title":"Turk J Gastroenterol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.03.017","article-title":"Global burden of liver disease: 2023 update","volume":"79","author":"Devarbhavi H","year":"2023","unstructured":"Devarbhavi H, Asrani SK, Arab JP, Nartey YA, Pose E, Kamath PS. Global burden of liver disease: 2023 update. J Hepatol. 2023, 79:516-37. 10.1016\/j.jhep.2023.03.017","journal-title":"J Hepatol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-022-00688-6","article-title":"Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors","volume":"20","author":"Huang DQ","year":"2023","unstructured":"Huang DQ, Mathurin P, Cortez-Pinto H, Loomba R. Global epidemiology of alcohol-associated cirrhosis and HCC: trends, projections and risk factors. Nat Rev Gastroenterol Hepatol. 2023, 20:37-49. 10.1038\/s41575-022-00688-6","journal-title":"Nat Rev Gastroenterol Hepatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/microorganisms10101887","article-title":"Visceral leishmaniasis: epidemiology, diagnosis, and treatment regimens in different geographical areas with a focus on pediatrics","volume":"10","author":"Scarpini S","year":"2022","unstructured":"Scarpini S, Dondi A, Totaro C, et al.. Visceral leishmaniasis: epidemiology, diagnosis, and treatment regimens in different geographical areas with a focus on pediatrics. Microorganisms. 2022, 10:10.3390\/microorganisms10101887","journal-title":"Microorganisms"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022017141","article-title":"Visceral leishmaniasis in the differential diagnosis of pancytopenia","volume":"140","author":"Tang Y","year":"2022","unstructured":"Tang Y, Kurzer JH. Visceral leishmaniasis in the differential diagnosis of pancytopenia. Blood. 2022, 140:10.1182\/blood.2022017141","journal-title":"Blood"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.actatropica.2007.10.002","article-title":"Hyper-reactive malarial splenomegaly (HMS) in malaria endemic area in Eastern Sudan","volume":"105","author":"Allam MM","year":"2008","unstructured":"Allam MM, Alkadarou TA, Ahmed BG, et al.. Hyper-reactive malarial splenomegaly (HMS) in malaria endemic area in Eastern Sudan. Acta Trop. 2008, 105:196-9. 10.1016\/j.actatropica.2007.10.002","journal-title":"Acta Trop"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmae077","article-title":"Clinical and hematological profile of patients with pancytopenia at a tertiary medical center in Ethiopia","author":"Kiya GT","year":"2024","unstructured":"Kiya GT, Dandena E, Adissu W, Kebede E. Clinical and hematological profile of patients with pancytopenia at a tertiary medical center in Ethiopia. Lab Med. 2024, 10.1093\/labmed\/lmae077","journal-title":"Lab Med"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijid.2009.06.031","article-title":"Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature","volume":"14","author":"Buzgan T","year":"2010","unstructured":"Buzgan T, Karahocagil MK, Irmak H, Baran AI, Karsen H, Evirgen O, Akdeniz H. Clinical manifestations and complications in 1028 cases of brucellosis: a retrospective evaluation and review of the literature. Int J Infect Dis. 2010, 14:469-78. 10.1016\/j.ijid.2009.06.031","journal-title":"Int J Infect Dis"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.46910-0","article-title":"Haemophagocytosis in a patient with Crimean Congo haemorrhagic fever","volume":"56","author":"Cagatay A","year":"2007","unstructured":"Cagatay A, Kapmaz M, Karadeniz A, et al.. Haemophagocytosis in a patient with Crimean Congo haemorrhagic fever. J Med Microbiol. 2007, 56:1126-8. 10.1099\/jmm.0.46910-0","journal-title":"J Med Microbiol"},{"key":"ref22","article-title":"A pediatric case of malaria caused by Plasmodium vivax","volume":"12","author":"Kan\u0131k MK","year":"2018","unstructured":"Kan\u0131k MK, \u015eahin A, Dalg\u0131\u00e7 N, Y\u0131ld\u0131rmak ZY, Bayraktar B, Bilgin N. A pediatric case of malaria caused by Plasmodium vivax. J Pediatr Inf. 2018, 12:35-8.","journal-title":"J Pediatr Inf"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1080\/16078454.2019.1590961","article-title":"Etiology and clinico-hematological profile of pancytopenia: experience of a Mexican Tertiary Care Center and review of the literature","volume":"24","author":"Vargas-Carretero CJ","year":"2019","unstructured":"Vargas-Carretero CJ, Fernandez-Vargas OE, Ron-Maga\u00f1a AL, Padilla-Ortega JA, Ron-Guerrero CS, Barrera-Chairez E. Etiology and clinico-hematological profile of pancytopenia: experience of a Mexican Tertiary Care Center and review of the literature. Hematology. 2019, 24:399-404. 10.1080\/16078454.2019.1590961","journal-title":"Hematology"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1309\/AJCP50AEEYGREWUZ","article-title":"The differential diagnosis and bone marrow evaluation of new-onset pancytopenia","volume":"139","author":"Weinzierl EP","year":"2013","unstructured":"Weinzierl EP, Arber DA. The differential diagnosis and bone marrow evaluation of new-onset pancytopenia. Am J Clin Pathol. 2013, 139:9-29. 10.1309\/AJCP50AEEYGREWUZ","journal-title":"Am J Clin Pathol"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-01-0161","article-title":"The epidemiology of aplastic anemia in Thailand","volume":"107","author":"Issaragrisil S","year":"2006","unstructured":"Issaragrisil S, Kaufman DW, Anderson T, Chansung K, Leaverton PE, Shapiro S, Young NS. The epidemiology of aplastic anemia in Thailand. Blood. 2006, 107:1299-307. 10.1182\/blood-2005-01-0161","journal-title":"Blood"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.24933","article-title":"Spectrum of pancytopenia in adults attending a clinical hematology department: a four-year experience from a tertiary care center of Western India","volume":"14","author":"Patel GR","year":"2022","unstructured":"Patel GR, Prajapati GR. Spectrum of pancytopenia in adults attending a clinical hematology department: a four-year experience from a tertiary care center of Western India. Cureus. 2022, 14:10.7759\/cureus.24933","journal-title":"Cureus"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.11604\/pamj.2019.34.149.18749","article-title":"Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia","volume":"34","author":"Sarbay H","year":"2019","unstructured":"Sarbay H. Comparison of the severity of cytopenias with etiologic factors in patients with pancytopenia and bicytopenia. Pan Afr Med J. 2019, 34:10.11604\/pamj.2019.34.149.18749","journal-title":"Pan Afr Med J"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.18203\/2349-3933.ijam20183125","article-title":"Evaluation of pancytopenia on bone marrow aspiration- study at a tertiary care center in Kashmir valley, India","volume":"5","author":"Khan SP","year":"2018","unstructured":"Khan SP, Geelani S, Khan FP, et al.. Evaluation of pancytopenia on bone marrow aspiration- study at a tertiary care center in Kashmir valley, India. Int J Adv Med. 2018, 5:946-9. 10.18203\/2349-3933.ijam20183125","journal-title":"Int J Adv Med"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.30449","article-title":"Clinical and etiological profiles of patients with pancytopenia in a tertiary care hospital","volume":"14","author":"Gajbhiye SS","year":"2022","unstructured":"Gajbhiye SS, Karwa AR, Dhok A, Jadhav SS. Clinical and etiological profiles of patients with pancytopenia in a tertiary care hospital. Cureus. 2022, 14:10.7759\/cureus.30449","journal-title":"Cureus"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200326100-00003","article-title":"Drug-induced myelosuppression: diagnosis and management","volume":"26","author":"Carey PJ","year":"2003","unstructured":"Carey PJ. Drug-induced myelosuppression: diagnosis and management. Drug Saf. 2003, 26:691-706. 10.2165\/00002018-200326100-00003","journal-title":"Drug Saf"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.glmedi.2024.100118","article-title":"An autopsy presentation of spontaneous splenic rupture in chronic myeloid leukemia: a rare case report","volume":"4","author":"Kanani J","year":"2024","unstructured":"Kanani J, Sheikh MI. An autopsy presentation of spontaneous splenic rupture in chronic myeloid leukemia: a rare case report. J Med Surg Public Health. 2024, 4:10.1016\/j.glmedi.2024.100118","journal-title":"J Med Surg Public Health"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s42000-020-00227-5","article-title":"Graves' hyperthyroidism-related pancytopenia: a case report with literature review","volume":"20","author":"Scappaticcio L","year":"2021","unstructured":"Scappaticcio L, Bellastella G, Maiorino MI, et al.. Graves' hyperthyroidism-related pancytopenia: a case report with literature review. Hormones (Athens). 2021, 20:93-100. 10.1007\/s42000-020-00227-5","journal-title":"Hormones (Athens)"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.45034","article-title":"Iron deficiency anemia presenting with pancytopenia: a study from India","volume":"15","author":"Meena M","year":"2023","unstructured":"Meena M, Khichar S, Pawar A, et al.. Iron deficiency anemia presenting with pancytopenia: a study from India. Cureus. 2023, 15:10.7759\/cureus.45034","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/333450-evaluation-of-etiological-causes-and-incidence-of-pancytopenia-a-case-series-from-a-tertiary-care-center","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T06:49:00Z","timestamp":1740293340000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/333450-evaluation-of-etiological-causes-and-incidence-of-pancytopenia-a-case-series-from-a-tertiary-care-center"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,22]]},"references-count":33,"URL":"https:\/\/doi.org\/10.7759\/cureus.79485","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,22]]}}}