{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,24]],"date-time":"2025-02-24T05:22:15Z","timestamp":1740374535347,"version":"3.37.3"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,23]]},"DOI":"10.7759\/cureus.79522","type":"journal-article","created":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T22:55:36Z","timestamp":1740351336000},"source":"Crossref","is-referenced-by-count":0,"title":["The Detection of Porphyromonas Gingivalis in Geriatrics and Its Associated Periodontal and Clinical Factors"],"prefix":"10.7759","author":[{"given":"Aina Nabilah","family":"Suhaimi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yashdev Atri","family":"Roop Kishore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohd Shaiful Ehsan","family":"Shalihin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hairul Aini","family":"Hamzah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sulhi","family":"Abidin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edre","family":"Mohammad Aidid","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ramli","family":"Musa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"World Health Organization. Ageing and health. (2022). Accessed: February 23, 2025: https:\/\/www.who.int\/news-room\/fact-sheets\/detail\/ageing-and-health."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1162\/daed_a_00332","article-title":"Global population aging: facts, challenges, solutions and perspectives","volume":"144","author":"Bloom DE","year":"2015","unstructured":"Bloom DE, Canning D, Lubet A. Global population aging: facts, challenges, solutions and perspectives. Daedalus. 2015, 144:80-92. 10.1162\/daed_a_00332","journal-title":"Daedalus"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2021.111273","article-title":"The oral microbiome and inflammation in mild cognitive impairment","volume":"147","author":"Yang I","year":"2021","unstructured":"Yang I, Arthur RA, Zhao L, et al.. The oral microbiome and inflammation in mild cognitive impairment. Exp Gerontol. 2021, 147:111273. 10.1016\/j.exger.2021.111273","journal-title":"Exp Gerontol"},{"key":"ref4","unstructured":"Centers for Disease Control and Prevention. Oral health tips for adults. (2023). Accessed: February 23, 2025: https:\/\/www.cdc.gov\/oralhealth\/basics\/adult-oral-health\/."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/jgs.17978","article-title":"Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies","volume":"70","author":"Asher S","year":"2022","unstructured":"Asher S, Stephen R, M\u00e4ntyl\u00e4 P, Suominen AL, Solomon A. Periodontal health, cognitive decline, and dementia: A systematic review and meta-analysis of longitudinal studies. J Am Geriatr Soc. 2022, 70:2695-709. 10.1111\/jgs.17978","journal-title":"J Am Geriatr Soc"},{"key":"ref6","article-title":"The clinical implications of Porphyromonas gingivalis and its detection methods - a systematic review","volume":"78","author":"Shalihin MS","year":"2023","unstructured":"Shalihin MS, Suhaimi NA, Hamzah HA, et al.. The clinical implications of Porphyromonas gingivalis and its detection methods - a systematic review. Med J Malaysia. 2023, 78:830-44.","journal-title":"Med J Malaysia"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1155\/2020\/2146160","article-title":"Global prevalence of periodontal disease and lack of its surveillance","volume":"2020","author":"Nazir M","year":"2020","unstructured":"Nazir M, Al-Ansari A, Al-Khalifa K, et al.. Global prevalence of periodontal disease and lack of its surveillance. Sci Wor Jr. 2020, 2020:2146160. 10.1155\/2020\/2146160","journal-title":"Sci Wor Jr"},{"key":"ref8","unstructured":"Institute for Health Metrics and Evaluation. Global burden of disease. (2021). Accessed: February 23, 2025: https:\/\/www.healthdata.org\/research-analysis\/gbd."},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2016.00053","article-title":"Porphyromonas gingivalis: An overview of periodontopathic pathogen below the gum line","volume":"7","author":"How KY","year":"2016","unstructured":"How KY, Song KP, Chan KG. Porphyromonas gingivalis: An overview of periodontopathic pathogen below the gum line. Front Microbiol. 2016, 7:53. 10.3389\/fmicb.2016.00053","journal-title":"Front Microbiol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.tim.2021.01.010","article-title":"Porphyromonas gingivalis","volume":"29","author":"Reyes L","year":"2021","unstructured":"Reyes L. Porphyromonas gingivalis. Trends Microbiol. 2021, 29:376-7. 10.1016\/j.tim.2021.01.010","journal-title":"Trends Microbiol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.15171\/joddd.2016.022","article-title":"Culture-based identification of pigmented Porphyromonas and Prevotella species in primary endodontic infections","volume":"10","author":"Rajaram A","year":"2016","unstructured":"Rajaram A, Kotrashetti VS, Somannavar PD, et al.. Culture-based identification of pigmented Porphyromonas and Prevotella species in primary endodontic infections. J Dent Res Dent Clin Dent Prospects. 2016, 10:136-41. 10.15171\/joddd.2016.022","journal-title":"J Dent Res Dent Clin Dent Prospects"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.20982\/tqmp.03.2.p043","article-title":"Understanding power and rules of thumb for determining sample sizes","volume":"3","author":"Wilson VC","year":"2007","unstructured":"Wilson VC, Morgan B. Understanding power and rules of thumb for determining sample sizes. Tut Qua Met Psy. 2007, 3:43-50. 10.20982\/tqmp.03.2.p043","journal-title":"Tut Qua Met Psy"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1111\/jcpe.12946","article-title":"Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions","volume":"45 Suppl 20","author":"Papapanou PN","year":"2018","unstructured":"Papapanou PN, Sanz M, Buduneli N, et al.. Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Clin Periodontol. 2018, 45 Suppl 20:S162-70. 10.1111\/jcpe.12946","journal-title":"J Clin Periodontol"},{"key":"ref14","article-title":"Periodontal Disease","author":"Gasner NS","year":"2023","unstructured":"Gasner NS, Schure RS. Periodontal Disease. StatPearls Publishing, 2023."},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/prd.12145","article-title":"Periodontitis prevalence in adults \u2265\u00a065\u00a0years of age, in the USA","volume":"72","author":"Eke PI","year":"2016","unstructured":"Eke PI, Wei L, Borgnakke WS, et al.. Periodontitis prevalence in adults \u2265\u00a065\u00a0years of age, in the USA. Periodontol. 2016, 72:76-95. 10.1111\/prd.12145","journal-title":"Periodontol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1080\/00016357.2018.1469788","article-title":"Distribution of Porphyromonas gingivalis fimA genotypes in patients affected by rheumatoid arthritis and periodontitis","volume":"76","author":"Ayala-Herrera JL","year":"2018","unstructured":"Ayala-Herrera JL, Abud-Mendoza C, Gonzalez-Amaro RF, et al.. Distribution of Porphyromonas gingivalis fimA genotypes in patients affected by rheumatoid arthritis and periodontitis. Acta Odontol Scand. 2018, 76:520-4. 10.1080\/00016357.2018.1469788","journal-title":"Acta Odontol Scand"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1536\/ihj.17-480","article-title":"Increased oral Porphyromonas gingivalis prevalence in cardiovascular patients with uncontrolled diabetes mellitus","volume":"59","author":"Aoyama N","year":"2018","unstructured":"Aoyama N, Suzuki JI, Kobayashi N, et al.. Increased oral Porphyromonas gingivalis prevalence in cardiovascular patients with uncontrolled diabetes mellitus. Int Heart J. 2018, 59:802-7. 10.1536\/ihj.17-480","journal-title":"Int Heart J"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.15517\/ijds.2022.49232","article-title":"Fluido crevicular gingival como biomarcador de enfermedad de Alzheimer","volume":"24","author":"Sansores-Espa\u00f1a LD","year":"2022","unstructured":"Sansores-Espa\u00f1a LD, Morales F, Arriola-Pacheco F, et al.. Fluido crevicular gingival como biomarcador de enfermedad de Alzheimer. Odo Inter Jr Den Sci. 2022, 24:156-176. 10.15517\/ijds.2022.49232","journal-title":"Odo Inter Jr Den Sci"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4103\/jomfp.jomfp_163_21","article-title":"Detection and comparison of prevalence of Porphyromonas gingivalis through culture and real time-polymerase chain reaction in subgingival plaque samples of chronic periodontitis and healthy individuals","volume":"26","author":"Ingalagi P","year":"2022","unstructured":"Ingalagi P, Bhat KG, Kulkarni RD, et al.. Detection and comparison of prevalence of Porphyromonas gingivalis through culture and real time-polymerase chain reaction in subgingival plaque samples of chronic periodontitis and healthy individuals. J Oral Maxillofac Pathol. 2022, 26:288. 10.4103\/jomfp.jomfp_163_21","journal-title":"J Oral Maxillofac Pathol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2007.060264","article-title":"Case definitions for use in population-based surveillance of periodontitis","volume":"78 Suppl 7S","author":"Page RC","year":"2007","unstructured":"Page RC, Eke PI. Case definitions for use in population-based surveillance of periodontitis. J Periodontol. 2007, 78 Suppl 7S:1387-99. 10.1902\/jop.2007.060264","journal-title":"J Periodontol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.4103\/2231-0754.173791","article-title":"Prevalence of Porphyromonas gingivalis and its relationship with herpesvirus in Indian subjects with chronic periodontitis: A cross-sectional study","volume":"8","author":"Joshi V","year":"2016","unstructured":"Joshi V, Bhat K, Kugaji M, et al.. Prevalence of Porphyromonas gingivalis and its relationship with herpesvirus in Indian subjects with chronic periodontitis: A cross-sectional study. Jr Inter Clin Den Res Org. 2016, 8:106-10. 10.4103\/2231-0754.173791","journal-title":"Jr Inter Clin Den Res Org"},{"key":"ref22","article-title":"Molecular detection of Porphyromonas gingivalis in chronic periodontitis patients","volume":"19","author":"Kulkarni PG","year":"2018","unstructured":"Kulkarni PG, Gosavi S, Haricharan PB, et al.. Molecular detection of Porphyromonas gingivalis in chronic periodontitis patients. J Contemp Dent Pract. 2018, 19:992-6.","journal-title":"J Contemp Dent Pract"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.4103\/0976-237X.194097","article-title":"Detection of Porphyromonas gingivalis and Treponema denticola in chronic and aggressive periodontitis patients: A comparative polymerase chain reaction study","volume":"7","author":"Kumawat RM","year":"2016","unstructured":"Kumawat RM, Ganvir SM, Hazarey VK, et al.. Detection of Porphyromonas gingivalis and Treponema denticola in chronic and aggressive periodontitis patients: A comparative polymerase chain reaction study. Contemp Clin Dent. 2016, 7:481-6. 10.4103\/0976-237X.194097","journal-title":"Contemp Clin Dent"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.15218\/zjms.2015.0034","article-title":"The impact of the presence of Porphyromonas gingivalis on periodontal health in a group of patients with periodontitis in Erbil","volume":"19","author":"Abdulaziz S","year":"2015","unstructured":"Abdulaziz S, Said A, Mustafa S. The impact of the presence of Porphyromonas gingivalis on periodontal health in a group of patients with periodontitis in Erbil. Zan Jr Med Sci. 2015, 19:1069-1074. 10.15218\/zjms.2015.0034","journal-title":"Zan Jr Med Sci"},{"key":"ref25","article-title":"Positive correlations between presence of gram negative enteric rods and Porphyromonas gingivalis in subgingival plaque","volume":"24","author":"Ardila CM","year":"2011","unstructured":"Ardila CM, L\u00f3pez MA, Guzm\u00e1n IC. Positive correlations between presence of gram negative enteric rods and Porphyromonas gingivalis in subgingival plaque. Acta Odontol Latinoam. 2011, 24:15-9.","journal-title":"Acta Odontol Latinoam"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.120.16790","article-title":"Association between periodontitis and blood pressure highlighted in systemically healthy individuals: results from a nested case-control study","volume":"77","author":"Mu\u00f1oz Aguilera E","year":"2021","unstructured":"Mu\u00f1oz Aguilera E, Suvan J, Orlandi M, et al.. Association between periodontitis and blood pressure highlighted in systemically healthy individuals: results from a nested case-control study. Hypertension. 2021, 77:1765-74. 10.1161\/HYPERTENSIONAHA.120.16790","journal-title":"Hypertension"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bdj.2014.907","article-title":"Diabetes and periodontal disease: a two-way relationship","volume":"217","author":"Casanova L","year":"2014","unstructured":"Casanova L, Hughes FJ, Preshaw PM. Diabetes and periodontal disease: a two-way relationship. Br Dent J. 2014, 217:433-7. 10.1038\/sj.bdj.2014.907","journal-title":"Br Dent J"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2023.1141339","article-title":"Porphyromonas gingivalis-induced periodontitis could contribute to cognitive impairment in Sprague-Dawley rats via the P38 MAPK signaling pathway","volume":"17","author":"Jin R","year":"2023","unstructured":"Jin R, Ning X, Liu X, Zhao Y, Ye G. Porphyromonas gingivalis-induced periodontitis could contribute to cognitive impairment in Sprague-Dawley rats via the P38 MAPK signaling pathway. Front Cell Neurosci. 2023, 17:1141339. 10.3389\/fncel.2023.1141339","journal-title":"Front Cell Neurosci"},{"key":"ref29","unstructured":"Neuroscience News. Oral microbiome may influence cognitive decline and brain health. (2023). Accessed: February 23, 2025: https:\/\/neurosciencenews.com\/oral-microbiome-cognition-28391\/."},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-024-04119-2","article-title":"Oral microbiota and Porphyromonas gingivalis Kgp genotypes altered in Parkinson's disease with mild cognitive impairment","volume":"61","author":"Li D","year":"2024","unstructured":"Li D, Ren T, Li H, et al.. Oral microbiota and Porphyromonas gingivalis Kgp genotypes altered in Parkinson's disease with mild cognitive impairment. Mol Neurobiol. 2024, 61:8631-9. 10.1007\/s12035-024-04119-2","journal-title":"Mol Neurobiol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/344851-the-detection-of-porphyromonas-gingivalis-in-geriatrics-and-its-associated-periodontal-and-clinical-factors","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,23]],"date-time":"2025-02-23T22:55:40Z","timestamp":1740351340000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/344851-the-detection-of-porphyromonas-gingivalis-in-geriatrics-and-its-associated-periodontal-and-clinical-factors"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,23]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.79522","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,23]]}}}