{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,24]],"date-time":"2026-01-24T08:31:45Z","timestamp":1769243505549,"version":"3.49.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,2,25]]},"DOI":"10.7759\/cureus.79620","type":"journal-article","created":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T12:46:47Z","timestamp":1740487607000},"source":"Crossref","is-referenced-by-count":1,"title":["Invasive Fungal Infections in the Neonatal Intensive Care Unit"],"prefix":"10.7759","author":[{"given":"Sabina","family":"Terzic","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alma","family":"Zgalj","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.7196\/AJTCCM.2022.v28i3.264","article-title":"Invasive fungal infections","volume":"28","author":"Kwarteng Owusu S","year":"2022","unstructured":"Kwarteng Owusu S. Invasive fungal infections. Afr J Thorac Crit Care Med. 2022, 28:100-1. 10.7196\/AJTCCM.2022.v28i3.264","journal-title":"Afr J Thorac Crit Care Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.2013.811925","article-title":"Invasive fungal infections in newborns and current management strategies","volume":"11","author":"Hundalani S","year":"2013","unstructured":"Hundalani S, Pammi M. Invasive fungal infections in newborns and current management strategies. Expert Rev Anti Infect Ther. 2013, 11:709-21. 10.1586\/14787210.2013.811925","journal-title":"Expert Rev Anti Infect Ther"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1542\/peds.110.2.285","article-title":"Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network","volume":"110","author":"Stoll BJ","year":"2002","unstructured":"Stoll BJ, Hansen N, Fanaroff AA, et al.. Late-onset sepsis in very low birth weight neonates: the experience of the NICHD Neonatal Research Network. Pediatrics. 2002, 110:285-91. 10.1542\/peds.110.2.285","journal-title":"Pediatrics"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-0671","article-title":"Changes in the incidence of candidiasis in neonatal intensive care units","volume":"133","author":"Aliaga S","year":"2014","unstructured":"Aliaga S, Clark RH, Laughon M, et al.. Changes in the incidence of candidiasis in neonatal intensive care units. Pediatrics. 2014, 133:236-42. 10.1542\/peds.2013-0671","journal-title":"Pediatrics"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/pix046","article-title":"Epidemiology of invasive fungal disease in children","volume":"6","author":"Pana ZD","year":"2017","unstructured":"Pana ZD, Roilides E, Warris A, Groll AH, Zaoutis T. Epidemiology of invasive fungal disease in children. J Pediatric Infect Dis Soc. 2017, 6:S3-S11. 10.1093\/jpids\/pix046","journal-title":"J Pediatric Infect Dis Soc"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2009-3412","article-title":"Neonatal candidiasis: epidemiology, risk factors, and clinical judgment","volume":"126","author":"Benjamin DK Jr","year":"2010","unstructured":"Benjamin DK Jr, Stoll BJ, Gantz MG, et al.. Neonatal candidiasis: epidemiology, risk factors, and clinical judgment. Pediatrics. 2010, 126:e865-73. 10.1542\/peds.2009-3412","journal-title":"Pediatrics"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.anpede.2021.07.008","article-title":"Incidence and factors associated with invasive candidiasis in a neonatal intensive care unit in Mexico","volume":"97","author":"Lona-Reyes JC","year":"2022","unstructured":"Lona-Reyes JC, G\u00f3mez-Ruiz LM, Cordero-Zamora A, Cort\u00e9s-Gonz\u00e1lez SI, Quiles-Corona M, P\u00e9rez-Ram\u00edrez RO, Pinto-Macedo H. Incidence and factors associated with invasive candidiasis in a neonatal intensive care unit in Mexico. An Pediatr (Engl Ed). 2022, 97:79-86. 10.1016\/j.anpede.2021.07.008","journal-title":"An Pediatr (Engl Ed)"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2017.00142","article-title":"Bloodstream infection incidence of different central venous catheters in neonates: a descriptive cohort study","volume":"5","author":"Dubbink-Verheij GH","year":"2017","unstructured":"Dubbink-Verheij GH, Bekker V, Pelsma IC, et al.. Bloodstream infection incidence of different central venous catheters in neonates: a descriptive cohort study. Front Pediatr. 2017, 5:142. 10.3389\/fped.2017.00142","journal-title":"Front Pediatr"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/jpids\/piy009","article-title":"Neonatal and pediatric candidemia: results from population-based active laboratory surveillance in four US locations, 2009-2015","volume":"7","author":"Benedict K","year":"2018","unstructured":"Benedict K, Roy M, Kabbani S, et al.. Neonatal and pediatric candidemia: results from population-based active laboratory surveillance in four US locations, 2009-2015. J Pediatric Infect Dis Soc. 2018, 7:e78-85. 10.1093\/jpids\/piy009","journal-title":"J Pediatric Infect Dis Soc"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2017.09.080","article-title":"Exposure to gastric acid inhibitors increases the risk of infection in preterm very low birth weight infants but concomitant administration of lactoferrin counteracts this effect","volume":"193","author":"Manzoni P","year":"2018","unstructured":"Manzoni P, Garc\u00eda S\u00e1nchez R, Meyer M, et al.. Exposure to gastric acid inhibitors increases the risk of infection in preterm very low birth weight infants but concomitant administration of lactoferrin counteracts this effect. J Pediatr. 2018, 193:62-67.e1. 10.1016\/j.jpeds.2017.09.080","journal-title":"J Pediatr"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1179\/1973947814Y.0000000222","article-title":"Invasive fungal infection in neonatal intensive care units: a multicenter survey","volume":"28","author":"Baptista MI","year":"2016","unstructured":"Baptista MI, Nona J, Ferreira M, et al.. Invasive fungal infection in neonatal intensive care units: a multicenter survey. J Chemother. 2016, 28:37-43. 10.1179\/1973947814Y.0000000222","journal-title":"J Chemother"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/jof8050465","article-title":"Clinical and microbiological characteristics of neonates with candidemia and impacts of therapeutic strategies on the outcomes","volume":"8","author":"Chen YN","year":"2022","unstructured":"Chen YN, Hsu JF, Chu SM, et al.. Clinical and microbiological characteristics of neonates with candidemia and impacts of therapeutic strategies on the outcomes. J Fungi (Basel). 2022, 8:465. 10.3390\/jof8050465","journal-title":"J Fungi (Basel)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000001968","article-title":"Invasive fungal infections in neonates in Canada: epidemiology and outcomes","volume":"37","author":"Ting JY","year":"2018","unstructured":"Ting JY, Roberts A, Synnes A, Canning R, Bodani J, Monterossa L, Shah PS. Invasive fungal infections in neonates in Canada: epidemiology and outcomes. Pediatr Infect Dis J. 2018, 37:1154-9. 10.1097\/INF.0000000000001968","journal-title":"Pediatr Infect Dis J"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/mmy\/myx096","article-title":"Nationwide survey of neonatal invasive fungal infection in Japan","volume":"56","author":"Ishiwada N","year":"2018","unstructured":"Ishiwada N, Kitajima H, Morioka I, Takeuchi N, Endo M, Watanabe A, Kamei K. Nationwide survey of neonatal invasive fungal infection in Japan. Med Mycol. 2018, 56:679-86. 10.1093\/mmy\/myx096","journal-title":"Med Mycol"},{"key":"ref15","article-title":"Invasive candidiasis in neonatal intensive care unit","volume":"4","author":"Almazer Y","year":"2019","unstructured":"Almazer Y, Ashaq L, Aljohani E, et al.. Invasive candidiasis in neonatal intensive care unit. J Pediatr Neonat Disord. 2019, 4:1-10.","journal-title":"J Pediatr Neonat Disord"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.32641\/rchped.v90i2.717","article-title":"[Risk factors and lethality associated with neonatal candidemia in a neonatal unit]","volume":"90","author":"Capar\u00f3 Ingram E","year":"2019","unstructured":"Capar\u00f3 Ingram E, V\u00e1squez Vega M, Norero X, S\u00e1ez-Llorens X, DeAntonio R, Rodr\u00edguez Barr\u00eda E. [Risk factors and lethality associated with neonatal candidemia in a neonatal unit]. Rev Chil Pediatr. 2019, 90:186-93. 10.32641\/rchped.v90i2.717","journal-title":"Rev Chil Pediatr"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/7901763","article-title":"Candidemia in the neonatal intensive care unit: a retrospective, observational survey and analysis of literature data","volume":"2017","author":"Caggiano G","year":"2017","unstructured":"Caggiano G, Lovero G, De Giglio O, Barbuti G, Montagna O, Laforgia N, Montagna MT. Candidemia in the neonatal intensive care unit: a retrospective, observational survey and analysis of literature data. Biomed Res Int. 2017, 2017:7901763. 10.1155\/2017\/7901763","journal-title":"Biomed Res Int"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1177\/2333794X17696684","article-title":"Epidemiology of invasive fungal infections at two tertiary care neonatal intensive care units over a 12-year period (2000-2011)","volume":"4","author":"Agarwal RR","year":"2017","unstructured":"Agarwal RR, Agarwal RL, Chen X, Lua JL, Ang JY. Epidemiology of invasive fungal infections at two tertiary care neonatal intensive care units over a 12-year period (2000-2011). Glob Pediatr Health. 2017, 4:2333794X17696684. 10.1177\/2333794X17696684","journal-title":"Glob Pediatr Health"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4103\/npmj.npmj_104_17","article-title":"Invasive candidiasis in a neonatal intensive care unit in Lagos, Nigeria","volume":"24","author":"Ezenwa BN","year":"2017","unstructured":"Ezenwa BN, Oladele RO, Akintan PE, Fajolu IB, Oshun PO, Oduyebo OO, Ezeaka VC. Invasive candidiasis in a neonatal intensive care unit in Lagos, Nigeria. Niger Postgrad Med J. 2017, 24:150-4. 10.4103\/npmj.npmj_104_17","journal-title":"Niger Postgrad Med J"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3100-2","article-title":"Comparison of the incidence, clinical features and outcomes of invasive candidiasis in children and neonates","volume":"18","author":"Hsu JF","year":"2018","unstructured":"Hsu JF, Lai MY, Lee CW, et al.. Comparison of the incidence, clinical features and outcomes of invasive candidiasis in children and neonates. BMC Infect Dis. 2018, 18:194. 10.1186\/s12879-018-3100-2","journal-title":"BMC Infect Dis"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens10030319","article-title":"Invasive Candida infections in neonates after major surgery: current evidence and new directions","volume":"10","author":"De Rose DU","year":"2021","unstructured":"De Rose DU, Santisi A, Ronchetti MP, et al.. Invasive Candida infections in neonates after major surgery: current evidence and new directions. Pathogens. 2021, 10:319. 10.3390\/pathogens10030319","journal-title":"Pathogens"},{"key":"ref22","article-title":"Which patient in the neonatal intensive care unit should receive antifungal prophylaxis therapy?","volume":"23","author":"Hanna Pharm M","year":"2021","unstructured":"Hanna Pharm M, Mazkereth R. Which patient in the neonatal intensive care unit should receive antifungal prophylaxis therapy?. Isr Med Assoc J. 2021, 23:116-20.","journal-title":"Isr Med Assoc J"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3345\/cep.2019.01431","article-title":"Fluconazole prophylaxis against invasive candidiasis in very low and extremely low birth weight preterm neonates: a systematic review and meta-analysis","volume":"64","author":"Robati Anaraki M","year":"2021","unstructured":"Robati Anaraki M, Nouri-Vaskeh M, Abdoli Oskoei S. Fluconazole prophylaxis against invasive candidiasis in very low and extremely low birth weight preterm neonates: a systematic review and meta-analysis. Clin Exp Pediatr. 2021, 64:172-9. 10.3345\/cep.2019.01431","journal-title":"Clin Exp Pediatr"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky353","article-title":"Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants","volume":"73","author":"Autmizguine J","year":"2018","unstructured":"Autmizguine J, Smith PB, Prather K, et al.. Effect of fluconazole prophylaxis on Candida fluconazole susceptibility in premature infants. J Antimicrob Chemother. 2018, 73:3482-7. 10.1093\/jac\/dky353","journal-title":"J Antimicrob Chemother"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1080\/09537104.2017.1293810","article-title":"Value of platelet count in the early diagnosis of nosocomial invasive fungal infections in premature infants","volume":"29","author":"Yang YC","year":"2018","unstructured":"Yang YC, Mao J. Value of platelet count in the early diagnosis of nosocomial invasive fungal infections in premature infants. Platelets. 2018, 29:65-70. 10.1080\/09537104.2017.1293810","journal-title":"Platelets"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002317","article-title":"Management of invasive fungal disease in neonates and children","volume":"38","author":"Ferreras-Antol\u00edn L","year":"2019","unstructured":"Ferreras-Antol\u00edn L, Sharland M, Warris A. Management of invasive fungal disease in neonates and children. Pediatr Infect Dis J. 2019, 38:S2-6. 10.1097\/INF.0000000000002317","journal-title":"Pediatr Infect Dis J"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13053","article-title":"Epidemiological features of nosocomial candidaemia in neonates, infants and children: a multicentre study in Iran","volume":"63","author":"Ahangarkani F","year":"2020","unstructured":"Ahangarkani F, Shokohi T, Rezai MS, et al.. Epidemiological features of nosocomial candidaemia in neonates, infants and children: a multicentre study in Iran. Mycoses. 2020, 63:382-94. 10.1111\/myc.13053","journal-title":"Mycoses"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3389\/fped.2017.00054","article-title":"Candida parapsilosis protects premature intestinal epithelial cells from invasion and damage by Candida albicans","volume":"5","author":"Gonia S","year":"2017","unstructured":"Gonia S, Archambault L, Shevik M, et al.. Candida parapsilosis protects premature intestinal epithelial cells from invasion and damage by Candida albicans. Front Pediatr. 2017, 5:54. 10.3389\/fped.2017.00054","journal-title":"Front Pediatr"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000002530","article-title":"Etiology and outcome of candidemia in neonates and children in Europe: an 11-year multinational retrospective study","volume":"39","author":"Warris A","year":"2020","unstructured":"Warris A, Pana ZD, Oletto A, et al.. Etiology and outcome of candidemia in neonates and children in Europe: an 11-year multinational retrospective study. Pediatr Infect Dis J. 2020, 39:114-20. 10.1097\/INF.0000000000002530","journal-title":"Pediatr Infect Dis J"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/339023-invasive-fungal-infections-in-the-neonatal-intensive-care-unit","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,2,25]],"date-time":"2025-02-25T12:46:49Z","timestamp":1740487609000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/339023-invasive-fungal-infections-in-the-neonatal-intensive-care-unit"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,2,25]]},"references-count":29,"URL":"https:\/\/doi.org\/10.7759\/cureus.79620","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,2,25]]}}}