{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,23]],"date-time":"2026-09-23T02:26:41Z","timestamp":1790130401265,"version":"4.0.1"},"reference-count":50,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,4]]},"DOI":"10.7759\/cureus.80025","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T14:18:03Z","timestamp":1741097883000},"source":"Crossref","is-referenced-by-count":2,"title":["Stereotactic Radiosurgery for Intramedullary Spinal Cord Metastases: A Systematic Review and Meta-Analysis"],"prefix":"10.7759","author":[{"given":"Felipe","family":"Carvajal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Garc\u00eda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felipe","family":"Rojas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kita","family":"Sallabanda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-004-0386-1","article-title":"Intramedullary spinal cord metastases: diagnosis and treatment - an illustrated review","volume":"146","author":"Kalayci M","year":"2004","unstructured":"Kalayci M, Ca\u011favi F, G\u00fcl S, Yenid\u00fcnya S, A\u00e7ikg\u00f6z B. Intramedullary spinal cord metastases: diagnosis and treatment - an illustrated review. Acta Neurochir (Wien). 2004, 146:1347-54. 10.1007\/s00701-004-0386-1","journal-title":"Acta Neurochir (Wien)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S193235","article-title":"Intramedullary spinal cord metastasis in malignancies: an institutional analysis and review","volume":"12","author":"Lv J","year":"2019","unstructured":"Lv J, Liu B, Quan X, Li C, Dong L, Liu M. Intramedullary spinal cord metastasis in malignancies: an institutional analysis and review. Onco Targets Ther. 2019, 12:4741-53. 10.2147\/OTT.S193235","journal-title":"Onco Targets Ther"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3171\/2015.5.FOCUS15149","article-title":"Intramedullary spinal cord metastases: an increasingly common diagnosis","volume":"39","author":"Payer S","year":"2015","unstructured":"Payer S, Mende KC, Westphal M, Eicker SO. Intramedullary spinal cord metastases: an increasingly common diagnosis. Neurosurg Focus. 2015, 39:E15. 10.3171\/2015.5.FOCUS15149","journal-title":"Neurosurg Focus"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.22.12.1222","article-title":"Intramedullary spinal cord metastases. Clinical and radiographic findings in nine cases","volume":"22","author":"Edelson RN","year":"1972","unstructured":"Edelson RN, Deck MD, Posner JB. Intramedullary spinal cord metastases. Clinical and radiographic findings in nine cases. Neurology. 1972, 22:1222-31. 10.1212\/wnl.22.12.1222","journal-title":"Neurology"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3171\/foc.2004.16.6.3","article-title":"Cauda equina syndrome caused by primary and metastatic neoplasms","volume":"16","author":"Bagley CA","year":"2004","unstructured":"Bagley CA, Gokaslan ZL. Cauda equina syndrome caused by primary and metastatic neoplasms. Neurosurg Focus. 2004, 16:e3. 10.3171\/foc.2004.16.6.3","journal-title":"Neurosurg Focus"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-007-9345-z","article-title":"Intramedullary spinal cord metastases: a single-institution experience","volume":"84","author":"Lee SS","year":"2007","unstructured":"Lee SS, Kim MK, Sym SJ, Kim SW, Kim WK, Kim SB, Ahn JH. Intramedullary spinal cord metastases: a single-institution experience. J Neurooncol. 2007, 84:85-9. 10.1007\/s11060-007-9345-z","journal-title":"J Neurooncol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1212\/wnl.47.4.906","article-title":"Intramedullary spinal cord metastases: clinical features and treatment outcome","volume":"47","author":"Schiff D","year":"1996","unstructured":"Schiff D, O'Neill BP. Intramedullary spinal cord metastases: clinical features and treatment outcome. Neurology. 1996, 47:906-12. 10.1212\/wnl.47.4.906","journal-title":"Neurology"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2012.04.005","article-title":"Intramedullary spinal cord metastases: a 20-year institutional experience with a comprehensive literature review","volume":"79","author":"Sung WS","year":"2013","unstructured":"Sung WS, Sung MJ, Chan JH, et al.. Intramedullary spinal cord metastases: a 20-year institutional experience with a comprehensive literature review. World Neurosurg. 2013, 79:576-84. 10.1016\/j.wneu.2012.04.005","journal-title":"World Neurosurg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.hemonc.2017.07.003","article-title":"Multimodality therapy improves survival in intramedullary spinal cord metastasis of lung primary","volume":"10","author":"Saeed H","year":"2017","unstructured":"Saeed H, Patel R, Thakkar J, Hamoodi L, Chen L, Villano JL. Multimodality therapy improves survival in intramedullary spinal cord metastasis of lung primary. Hematol Oncol Stem Cell Ther. 2017, 10:143-50. 10.1016\/j.hemonc.2017.07.003","journal-title":"Hematol Oncol Stem Cell Ther"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-015-0654-y","article-title":"The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms: a systematic literature review","volume":"39","author":"Hern\u00e1ndez-Dur\u00e1n S","year":"2016","unstructured":"Hern\u00e1ndez-Dur\u00e1n S, Hanft S, Komotar RJ, Manzano GR. The role of stereotactic radiosurgery in the treatment of intramedullary spinal cord neoplasms: a systematic literature review. Neurosurg Rev. 2016, 39:175-83. 10.1007\/s10143-015-0654-y","journal-title":"Neurosurg Rev"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2017.03.005","article-title":"Introduction","volume":"27","author":"Koong AC","year":"2017","unstructured":"Koong AC, Tepper JE. Introduction. Semin Radiat Oncol. 2017, 27:189. 10.1016\/j.semradonc.2017.03.005","journal-title":"Semin Radiat Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.semradonc.2005.01.006","article-title":"Extracranial stereotactic radiation delivery","volume":"15","author":"Timmerman RD","year":"2005","unstructured":"Timmerman RD, Forster KM, Chinsoo Cho L. Extracranial stereotactic radiation delivery. Semin Radiat Oncol. 2005, 15:202-7. 10.1016\/j.semradonc.2005.01.006","journal-title":"Semin Radiat Oncol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1080\/02841860310013490","article-title":"Extracranial stereotactic radioablation: physical principles","volume":"42","author":"Papiez L","year":"2003","unstructured":"Papiez L, Timmerman R, DesRosiers C, Randall M. Extracranial stereotactic radioablation: physical principles. Acta Oncol. 2003, 42:882-94. 10.1080\/02841860310013490","journal-title":"Acta Oncol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n160","article-title":"PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"Page MJ","year":"2021","unstructured":"Page MJ, Moher D, Bossuyt PM, et al.. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021, 372:n160. 10.1136\/bmj.n160","journal-title":"BMJ"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.11124\/JBISRIR-D-19-00099","article-title":"Methodological quality of case series studies: an introduction to the JBI critical appraisal tool","volume":"18","author":"Munn Z","year":"2020","unstructured":"Munn Z, Barker TH, Moola S, et al.. Methodological quality of case series studies: an introduction to the JBI critical appraisal tool. JBI Evid Synth. 2020, 18:2127-33. 10.11124\/JBISRIR-D-19-00099","journal-title":"JBI Evid Synth"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13020297","article-title":"Image-guided robotic radiosurgery for the management of intramedullary spinal cord metastases-a multicenter experience","volume":"13","author":"Ehret F","year":"2021","unstructured":"Ehret F, Senger C, Kufeld M, et al.. Image-guided robotic radiosurgery for the management of intramedullary spinal cord metastases-a multicenter experience. Cancers (Basel). 2021, 13:297. 10.3390\/cancers13020297","journal-title":"Cancers (Basel)"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.clineuro.2009.06.008","article-title":"Fractionated radiosurgical management of intramedullary spinal cord metastasis: a case report and review of the literature","volume":"111","author":"Parikh S","year":"2009","unstructured":"Parikh S, Heron DE. Fractionated radiosurgical management of intramedullary spinal cord metastasis: a case report and review of the literature. Clin Neurol Neurosurg. 2009, 111:858-61. 10.1016\/j.clineuro.2009.06.008","journal-title":"Clin Neurol Neurosurg"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3171\/2009.9.FOCUS09194","article-title":"Stereotactic spine radiosurgery for intradural and intramedullary metastasis","volume":"27","author":"Shin DA","year":"2009","unstructured":"Shin DA, Huh R, Chung SS, Rock J, Ryu S. Stereotactic spine radiosurgery for intradural and intramedullary metastasis. Neurosurg Focus. 2009, 27:E10. 10.3171\/2009.9.FOCUS09194","journal-title":"Neurosurg Focus"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurol.2010.07.028","article-title":"Solitary intramedullary metastasis from malignant pleural mesothelioma treated with CyberKnife\u00ae: a case report","volume":"167","author":"Dewas S","year":"2011","unstructured":"Dewas S, Le Rhun E, Duhem R, Dansin E, Prevost B, Lartigau E. Solitary intramedullary metastasis from malignant pleural mesothelioma treated with CyberKnife\u00ae: a case report. Rev Neurol (Paris). 2011, 167:185-6. 10.1016\/j.neurol.2010.07.028","journal-title":"Rev Neurol (Paris)"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2012.02.002","article-title":"CyberKnife stereotactic radiosurgery for the treatment of intramedullary spinal cord metastases","volume":"19","author":"Veeravagu A","year":"2012","unstructured":"Veeravagu A, Lieberson RE, Mener A, et al.. CyberKnife stereotactic radiosurgery for the treatment of intramedullary spinal cord metastases. J Clin Neurosci. 2012, 19:1273-7. 10.1016\/j.jocn.2012.02.002","journal-title":"J Clin Neurosci"},{"key":"ref21","article-title":"Stereotactic radiotherapy for spinal intradural metastases developing within or adjacent to the previous irradiation field - report of three cases -","volume":"75","author":"Mori Y","year":"2013","unstructured":"Mori Y, Hashizume C, Shibamoto Y, Kobayashi T, Nakazawa H, Hagiwara M, Tsuwawa T. Stereotactic radiotherapy for spinal intradural metastases developing within or adjacent to the previous irradiation field - report of three cases -. Nagoya J Med Sci. 2013, 75:263-71.","journal-title":"Nagoya J Med Sci"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.609","article-title":"Robotic radiosurgery for the treatment of intramedullary spinal cord metastases: a case report and literature review","volume":"8","author":"Garcia R","year":"2016","unstructured":"Garcia R, Sallabanda K, Santa-Olalla I, et al.. Robotic radiosurgery for the treatment of intramedullary spinal cord metastases: a case report and literature review. Cureus. 2016, 8:e609. 10.7759\/cureus.609","journal-title":"Cureus"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.590","article-title":"Stereotactic radiotherapy for cervical spinal intramedullary metastasis and multiple brain metastases: a case report","volume":"8","author":"Mori Y","year":"2016","unstructured":"Mori Y, Kawamura T, Ohshima Y, Takeuchi A, Mori T, Ishiguchi T. Stereotactic radiotherapy for cervical spinal intramedullary metastasis and multiple brain metastases: a case report. Cureus. 2016, 8:e590. 10.7759\/cureus.590","journal-title":"Cureus"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.11.056","article-title":"Intramedullary spinal metastatic renal cell carcinoma: systematic review of disease presentation, treatment, and prognosis with case illustration","volume":"134","author":"Barrie U","year":"2020","unstructured":"Barrie U, Elguindy M, Pernik M, et al.. Intramedullary spinal metastatic renal cell carcinoma: systematic review of disease presentation, treatment, and prognosis with case illustration. World Neurosurg. 2020, 134:584-93. 10.1016\/j.wneu.2019.11.056","journal-title":"World Neurosurg"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-021-08901-6","article-title":"Stereotactic body radiotherapy for intramedullary metastases: a retrospective series at the Oscar Lambret center and a systematic review","volume":"21","author":"Tonneau M","year":"2021","unstructured":"Tonneau M, Mouttet-Audouard R, Le Tinier F, Mirabel X, Pasquier D. Stereotactic body radiotherapy for intramedullary metastases: a retrospective series at the Oscar Lambret center and a systematic review. BMC Cancer. 2021, 21:1168. 10.1186\/s12885-021-08901-6","journal-title":"BMC Cancer"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.21.2483","article-title":"Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial","volume":"295","author":"Aoyama H","year":"2006","unstructured":"Aoyama H, Shirato H, Tago M, et al.. Stereotactic radiosurgery plus whole-brain radiation therapy vs stereotactic radiosurgery alone for treatment of brain metastases: a randomized controlled trial. JAMA. 2006, 295:2483-91. 10.1001\/jama.295.21.2483","journal-title":"JAMA"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2016.9839","article-title":"Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases: a randomized clinical trial","volume":"316","author":"Brown PD","year":"2016","unstructured":"Brown PD, Jaeckle K, Ballman KV, et al.. Effect of radiosurgery alone vs radiosurgery with whole brain radiation therapy on cognitive function in patients with 1 to 3 brain metastases: a randomized clinical trial. JAMA. 2016, 316:401-9. 10.1001\/jama.2016.9839","journal-title":"JAMA"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(09)70263-3","article-title":"Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial","volume":"10","author":"Chang EL","year":"2009","unstructured":"Chang EL, Wefel JS, Hess KR, et al.. Neurocognition in patients with brain metastases treated with radiosurgery or radiosurgery plus whole-brain irradiation: a randomised controlled trial. Lancet Oncol. 2009, 10:1037-44. 10.1016\/S1470-2045(09)70263-3","journal-title":"Lancet Oncol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.30.1655","article-title":"Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study","volume":"29","author":"Kocher M","year":"2011","unstructured":"Kocher M, Soffietti R, Abacioglu U, et al.. Adjuvant whole-brain radiotherapy versus observation after radiosurgery or surgical resection of one to three cerebral metastases: results of the EORTC 22952-26001 study. J Clin Oncol. 2011, 29:134-41. 10.1200\/JCO.2010.30.1655","journal-title":"J Clin Oncol"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2023.10.016","article-title":"Prognostic scoring system for surgical treatment of intramedullary spinal cord metastases","volume":"118","author":"Gazzeri R","year":"2023","unstructured":"Gazzeri R, Telera S, Galarza M, Sperduti I, Alfieri A. Prognostic scoring system for surgical treatment of intramedullary spinal cord metastases. J Clin Neurosci. 2023, 118:90-5. 10.1016\/j.jocn.2023.10.016","journal-title":"J Clin Neurosci"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-019-03105-2","article-title":"Intramedullary spinal cord metastases: an institutional review of survival and outcomes","volume":"142","author":"Goyal A","year":"2019","unstructured":"Goyal A, Yolcu Y, Kerezoudis P, Alvi MA, Krauss WE, Bydon M. Intramedullary spinal cord metastases: an institutional review of survival and outcomes. J Neurooncol. 2019, 142:347-54. 10.1007\/s11060-019-03105-2","journal-title":"J Neurooncol"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.3171\/foc.1998.4.6.4","article-title":"Outcomes in patients treated with gamma knife radiosurgery for brain metastases from malignant melanoma","volume":"4","author":"Friehs GM","year":"1998","unstructured":"Friehs GM, Legat J, Zheng Z, Pendl G, Noren GC. Outcomes in patients treated with gamma knife radiosurgery for brain metastases from malignant melanoma. Neurosurg Focus. 1998, 4:e1. 10.3171\/foc.1998.4.6.4","journal-title":"Neurosurg Focus"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-021-01491-8","article-title":"Surgical treatment of intramedullary spinal cord metastases: functional outcome and complications-a multicenter study","volume":"44","author":"Gazzeri R","year":"2021","unstructured":"Gazzeri R, Telera S, Galarza M, Callovini GM, Isabella S, Alfieri A. Surgical treatment of intramedullary spinal cord metastases: functional outcome and complications-a multicenter study. Neurosurg Rev. 2021, 44:3267-75. 10.1007\/s10143-021-01491-8","journal-title":"Neurosurg Rev"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-024-02308-0","article-title":"Survival and neurological outcomes following management of intramedullary spinal metastasis patients: a case series with comprehensive review of the literature","volume":"47","author":"Kritikos M","year":"2024","unstructured":"Kritikos M, Vivanco-Suarez J, Teferi N, et al.. Survival and neurological outcomes following management of intramedullary spinal metastasis patients: a case series with comprehensive review of the literature. Neurosurg Rev. 2024, 47:75. 10.1007\/s10143-024-02308-0","journal-title":"Neurosurg Rev"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s11060-004-8097-2","article-title":"Metastasis to nervous system: spinal epidural and intramedullary metastases","volume":"75","author":"Mut M","year":"2005","unstructured":"Mut M, Schiff D, Shaffrey ME. Metastasis to nervous system: spinal epidural and intramedullary metastases. J Neurooncol. 2005, 75:43-56. 10.1007\/s11060-004-8097-2","journal-title":"J Neurooncol"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-007-0031-6","article-title":"Clinical outcome in patients with intramedullary spinal cord metastases from lung cancer","volume":"9","author":"Conill C","year":"2007","unstructured":"Conill C, Marruecos J, Verger E, et al.. Clinical outcome in patients with intramedullary spinal cord metastases from lung cancer. Clin Transl Oncol. 2007, 9:172-6. 10.1007\/s12094-007-0031-6","journal-title":"Clin Transl Oncol"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22555","article-title":"A review of hypofractionated palliative radiotherapy","volume":"109","author":"Lutz ST","year":"2007","unstructured":"Lutz ST, Chow EL, Hartsell WF, Konski AA. A review of hypofractionated palliative radiotherapy. Cancer. 2007, 109:1462-70. 10.1002\/cncr.22555","journal-title":"Cancer"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1016\/s0360-3016(01)02687-6","article-title":"Dose-volume effects in the rat cervical spinal cord after proton irradiation","volume":"52","author":"Bijl HP","year":"2002","unstructured":"Bijl HP, van Luijk P, Coppes RP, Schippers JM, Konings AWT, van der Kogel AJ. Dose-volume effects in the rat cervical spinal cord after proton irradiation. Int J Radiat Oncol Biol Phys. 2002, 52:205-11. 10.1016\/s0360-3016(01)02687-6","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1259\/0007-1285-60-719-1099","article-title":"The influence of field size on the late tolerance of the rat spinal cord to single doses of X rays","volume":"60","author":"Hopewell JW","year":"1987","unstructured":"Hopewell JW, Morris AD, Dixon-Brown A. The influence of field size on the late tolerance of the rat spinal cord to single doses of X rays. Br J Radiol. 1987, 60:1099-108. 10.1259\/0007-1285-60-719-1099","journal-title":"Br J Radiol"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)30932-6","article-title":"Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial","volume":"395","author":"Murray Brunt A","year":"2020","unstructured":"Murray Brunt A, Haviland JS, Wheatley DA, et al.. Hypofractionated breast radiotherapy for 1 week versus 3 weeks (FAST-Forward): 5-year efficacy and late normal tissue effects results from a multicentre, non-inferiority, randomised, phase 3 trial. Lancet. 2020, 395:1613-26. 10.1016\/S0140-6736(20)30932-6","journal-title":"Lancet"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2020.11.060","article-title":"Pain response after stereotactic body radiation therapy versus conventional radiation therapy in patients with bone metastases-a phase 2 randomized controlled trial within a prospective cohort","volume":"110","author":"Pielkenrood BJ","year":"2021","unstructured":"Pielkenrood BJ, van der Velden JM, van der Linden YM, et al.. Pain response after stereotactic body radiation therapy versus conventional radiation therapy in patients with bone metastases-a phase 2 randomized controlled trial within a prospective cohort. Int J Radiat Oncol Biol Phys. 2021, 110:358-67. 10.1016\/j.ijrobp.2020.11.060","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.esmoop.2023.101624","article-title":"Leptomeningeal metastasis from solid tumours: EANO-ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up","volume":"8","author":"Le Rhun E","year":"2023","unstructured":"Le Rhun E, Weller M, van den Bent M, et al.. Leptomeningeal metastasis from solid tumours: EANO-ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up. ESMO Open. 2023, 8:101624. 10.1016\/j.esmoop.2023.101624","journal-title":"ESMO Open"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1007\/s00066-024-02202-0","article-title":"DEGRO guideline for personalized radiotherapy of brain metastases and leptomeningeal carcinomatosis in patients with breast cancer","volume":"200","author":"Borm KJ","year":"2024","unstructured":"Borm KJ, Behzadi ST, H\u00f6rner-Rieber J, et al.. DEGRO guideline for personalized radiotherapy of brain metastases and leptomeningeal carcinomatosis in patients with breast cancer. Strahlenther Onkol. 2024, 200:259-75. 10.1007\/s00066-024-02202-0","journal-title":"Strahlenther Onkol"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1093\/neuonc\/noae103","article-title":"Leptomeningeal metastases from solid tumors: a Society for Neuro-Oncology and American Society of Clinical Oncology consensus review on clinical management and future directions","volume":"26","author":"Wilcox JA","year":"2024","unstructured":"Wilcox JA, Chukwueke UN, Ahn MJ, et al.. Leptomeningeal metastases from solid tumors: a Society for Neuro-Oncology and American Society of Clinical Oncology consensus review on clinical management and future directions. Neuro Oncol. 2024, 26:1781-804. 10.1093\/neuonc\/noae103","journal-title":"Neuro Oncol"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2019.09.038","article-title":"Spinal cord dose tolerance to stereotactic body radiation therapy","volume":"110","author":"Sahgal A","year":"2021","unstructured":"Sahgal A, Chang JH, Ma L, et al.. Spinal cord dose tolerance to stereotactic body radiation therapy. Int J Radiat Oncol Biol Phys. 2021, 110:124-36. 10.1016\/j.ijrobp.2019.09.038","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2009.05.023","article-title":"Spinal cord tolerance for stereotactic body radiotherapy","volume":"77","author":"Sahgal A","year":"2010","unstructured":"Sahgal A, Ma L, Gibbs I, et al.. Spinal cord tolerance for stereotactic body radiotherapy. Int J Radiat Oncol Biol Phys. 2010, 77:548-53. 10.1016\/j.ijrobp.2009.05.023","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2012.05.007","article-title":"Probabilities of radiation myelopathy specific to stereotactic body radiation therapy to guide safe practice","volume":"85","author":"Sahgal A","year":"2013","unstructured":"Sahgal A, Weinberg V, Ma L, et al.. Probabilities of radiation myelopathy specific to stereotactic body radiation therapy to guide safe practice. Int J Radiat Oncol Biol Phys. 2013, 85:341-7. 10.1016\/j.ijrobp.2012.05.007","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2017.05.053","article-title":"A detailed dosimetric analysis of spinal cord tolerance in high-dose spine radiosurgery","volume":"99","author":"Katsoulakis E","year":"2017","unstructured":"Katsoulakis E, Jackson A, Cox B, Lovelock M, Yamada Y. A detailed dosimetric analysis of spinal cord tolerance in high-dose spine radiosurgery. Int J Radiat Oncol Biol Phys. 2017, 99:598-607. 10.1016\/j.ijrobp.2017.05.053","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2010.01.040","article-title":"Tolerance of the spinal cord to stereotactic radiosurgery: insights from hemangioblastomas","volume":"80","author":"Daly ME","year":"2011","unstructured":"Daly ME, Choi CY, Gibbs IC, Adler JR Jr, Chang SD, Lieberson RE, Soltys SG. Tolerance of the spinal cord to stereotactic radiosurgery: insights from hemangioblastomas. Int J Radiat Oncol Biol Phys. 2011, 80:213-20. 10.1016\/j.ijrobp.2010.01.040","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2023.12.015","article-title":"Optimizing risk vs. reward in the era of ablative radiotherapy through calculated useful trauma (CUT)","volume":"119","author":"Sanford NN","year":"2024","unstructured":"Sanford NN, Timmerman RD. Optimizing risk vs. reward in the era of ablative radiotherapy through calculated useful trauma (CUT). Int J Radiat Oncol Biol Phys. 2024, 119:721-3. 10.1016\/j.ijrobp.2023.12.015","journal-title":"Int J Radiat Oncol Biol Phys"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/346754-stereotactic-radiosurgery-for-intramedullary-spinal-cord-metastases-a-systematic-review-and-meta-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T14:18:06Z","timestamp":1741097886000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/346754-stereotactic-radiosurgery-for-intramedullary-spinal-cord-metastases-a-systematic-review-and-meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,4]]},"references-count":50,"URL":"https:\/\/doi.org\/10.7759\/cureus.80025","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,4]]}}}