{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,3,5]],"date-time":"2025-03-05T05:41:10Z","timestamp":1741153270832,"version":"3.38.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,4]]},"DOI":"10.7759\/cureus.80028","type":"journal-article","created":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T16:28:31Z","timestamp":1741105711000},"source":"Crossref","is-referenced-by-count":0,"title":["Double Trouble: A Case of an Evolving Leg Ulcer in the Setting of Heart Failure"],"prefix":"10.7759","author":[{"given":"Osman","family":"Zuberi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Micah","family":"Pippin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diahann","family":"Marshall","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14744","article-title":"Association between venous leg ulcers and chronic heart failure: a Mendelian randomization study","volume":"21","author":"Ke C","year":"2024","unstructured":"Ke C, Zhou Q, Lu M, Xie R, Kong W. Association between venous leg ulcers and chronic heart failure: a Mendelian randomization study. Int Wound J. 2024, 21:e14744. 10.1111\/iwj.14744","journal-title":"Int Wound J"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1089\/wound.2020.1381","article-title":"Venous leg ulcers: a review of published assessment and treatment algorithms","volume":"11","author":"Bernatchez SF","year":"2022","unstructured":"Bernatchez SF, Eysaman-Walker J, Weir D. Venous leg ulcers: a review of published assessment and treatment algorithms. Adv Wound Care (New Rochelle). 2022, 11:28-41. 10.1089\/wound.2020.1381","journal-title":"Adv Wound Care (New Rochelle)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1177\/1358863X14568677","article-title":"Venous leg ulceration pathophysiology and evidence based treatment","volume":"20","author":"Chi YW","year":"2015","unstructured":"Chi YW, Raffetto JD. Venous leg ulceration pathophysiology and evidence based treatment. Vasc Med. 2015, 20:168-81. 10.1177\/1358863X14568677","journal-title":"Vasc Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvs.2012.10.121","article-title":"Venous disease in women: epidemiology, manifestations, and treatment","volume":"57","author":"Lohr JM","year":"2013","unstructured":"Lohr JM, Bush RL. Venous disease in women: epidemiology, manifestations, and treatment. J Vasc Surg. 2013, 57:37S-45S. 10.1016\/j.jvs.2012.10.121","journal-title":"J Vasc Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s13643-021-01697-3","article-title":"Prevalence and incidence of venous leg ulcers--a protocol for a systematic review","volume":"10","author":"Probst S","year":"2021","unstructured":"Probst S, Weller CD, Bobbink P, Saini C, Pugliese M, Skinner MB, Gethin G. Prevalence and incidence of venous leg ulcers--a protocol for a systematic review. Syst Rev. 2021, 10:148. 10.1186\/s13643-021-01697-3","journal-title":"Syst Rev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1177\/1534734619850444","article-title":"Prevalence of chronic illness and risk factors for chronic illness among patients with venous leg ulceration: a cross-sectional study","volume":"18","author":"Kelly M","year":"2019","unstructured":"Kelly M, Gethin G. Prevalence of chronic illness and risk factors for chronic illness among patients with venous leg ulceration: a cross-sectional study. Int J Low Extrem Wounds. 2019, 18:301-8. 10.1177\/1534734619850444","journal-title":"Int J Low Extrem Wounds"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1111\/iwj.14405","article-title":"Chronic venous insufficiency and venous leg ulcers: aetiology, on the pathophysiology-based treatment","volume":"21","author":"Krizanova O","year":"2023","unstructured":"Krizanova O, Penesova A, Hokynkova A, Pokorna A, Samadian A, Babula P. Chronic venous insufficiency and venous leg ulcers: aetiology, on the pathophysiology-based treatment. Int Wound J. 2023, 21:e14405. 10.1111\/iwj.14405","journal-title":"Int Wound J"},{"key":"ref8","article-title":"Venous Insufficiency","author":"Patel SK","year":"2024","unstructured":"Patel SK, Surowiec SM. Venous Insufficiency. StatPearls [Internet], Treasure Island (FL); 2024."},{"key":"ref9","article-title":"Venous ulcers: diagnosis and treatment","volume":"1","author":"Bonkemeyer Millan S","year":"2019","unstructured":"Bonkemeyer Millan S, Gan R, Townsend PE. Venous ulcers: diagnosis and treatment. Am Fam Physician. 2019, 1:298-305.","journal-title":"Am Fam Physician"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.31083\/j.rcm2510357","article-title":"Causal association of chronic venous insufficiency and cardiovascular diseases: a univariable and multivariable Mendelian randomization study","volume":"25","author":"Guo X","year":"2024","unstructured":"Guo X, Zhang K, Sun Y, Dong R. Causal association of chronic venous insufficiency and cardiovascular diseases: a univariable and multivariable Mendelian randomization study. Rev Cardiovasc Med. 2024, 25:357. 10.31083\/j.rcm2510357","journal-title":"Rev Cardiovasc Med"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.annder.2010.03.022","article-title":"[Heart failure and stasis ulcer: a significant association (prospective study of 100 cases)]","volume":"137","author":"Augey F","year":"2010","unstructured":"Augey F, Pinet A, Renaudier P. [Heart failure and stasis ulcer: a significant association (prospective study of 100 cases)]. Ann Dermatol Venereol. 2010, 137:353-8. 10.1016\/j.annder.2010.03.022","journal-title":"Ann Dermatol Venereol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2013.06.003","article-title":"Identification of symptom clusters in patients with chronic venous leg ulcers","volume":"47","author":"Edwards H","year":"2014","unstructured":"Edwards H, Finlayson K, Skerman H, Alexander K, Miaskowski C, Aouizerat B, Gibb M. Identification of symptom clusters in patients with chronic venous leg ulcers. J Pain Symptom Manage. 2014, 47:867-75. 10.1016\/j.jpainsymman.2013.06.003","journal-title":"J Pain Symptom Manage"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/ehf2.12848","article-title":"Compression therapy for leg oedema in patients with heart failure","volume":"7","author":"Urbanek T","year":"2020","unstructured":"Urbanek T, Ju\u015bko M, Kuczmik WB. Compression therapy for leg oedema in patients with heart failure. ESC Heart Fail. 2020, 7:2012-20. 10.1002\/ehf2.12848","journal-title":"ESC Heart Fail"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.23736\/S2724-5683.23.06130-6","article-title":"Venous ulcers: look at the patient, not at the ulcer! Risk factors and comorbid conditions in venous ulcers of lower limbs","volume":"71","author":"Garavello A","year":"2023","unstructured":"Garavello A, Fransvea P, Gilardi S, Fiamma P. Venous ulcers: look at the patient, not at the ulcer! Risk factors and comorbid conditions in venous ulcers of lower limbs. Minerva Cardiol Angiol. 2023, 71:575-81. 10.23736\/S2724-5683.23.06130-6","journal-title":"Minerva Cardiol Angiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jvsv.2018.07.014","article-title":"Risk factors associated with the venous leg ulcer that fails to heal after 1\u00a0year of treatment","volume":"7","author":"Melikian R","year":"2019","unstructured":"Melikian R, O'Donnell TF Jr, Suarez L, Iafrati MD. Risk factors associated with the venous leg ulcer that fails to heal after 1\u00a0year of treatment. J Vasc Surg Venous Lymphat Disord. 2019, 7:98-105. 10.1016\/j.jvsv.2018.07.014","journal-title":"J Vasc Surg Venous Lymphat Disord"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/322783-double-trouble-a-case-of-an-evolving-leg-ulcer-in-the-setting-of-heart-failure","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,4]],"date-time":"2025-03-04T16:28:33Z","timestamp":1741105713000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/322783-double-trouble-a-case-of-an-evolving-leg-ulcer-in-the-setting-of-heart-failure"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,4]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.80028","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,4]]}}}