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Foods. 2020, 9:947. 10.3390\/foods9070947","journal-title":"Foods"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/332633-expert-opinion-on-the-use-of-probiotics-in-general-gynecological-conditions","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,20]],"date-time":"2025-03-20T11:57:15Z","timestamp":1742471835000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/332633-expert-opinion-on-the-use-of-probiotics-in-general-gynecological-conditions"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,20]]},"references-count":52,"URL":"https:\/\/doi.org\/10.7759\/cureus.80875","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,20]]}}}