{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,30]],"date-time":"2025-08-30T16:27:12Z","timestamp":1756571232429,"version":"3.40.2"},"reference-count":26,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,3,24]]},"DOI":"10.7759\/cureus.81091","type":"journal-article","created":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T01:25:38Z","timestamp":1742865938000},"source":"Crossref","is-referenced-by-count":1,"title":["Whipple Procedure vs. Distal Pancreatectomy: A Study on the Efficacy, Survival Rates, and Complication Rates in Patients With Pancreatic Cancer"],"prefix":"10.7759","author":[{"given":"Hamza","family":"Siddique","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sabaina","family":"Arshad Tarar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmed Salman","family":"Majeed","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Hamza","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mueez","family":"Saleem Raja","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Haider Naqvi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Muhammad","family":"Zarar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fizza","family":"Chudhary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bilal","family":"Qammar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-200208000-00001","article-title":"Evidence-based pancreatic head resection for pancreatic cancer and chronic pancreatitis","volume":"236","author":"Sch\u00e4fer M","year":"2002","unstructured":"Sch\u00e4fer M, M\u00fcllhaupt B, Clavien PA. Evidence-based pancreatic head resection for pancreatic cancer and chronic pancreatitis. Ann Surg. 2002, 236:137-48. 10.1097\/00000658-200208000-00001","journal-title":"Ann Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0000000000000165","article-title":"Whipple made simple for surgical pathologists: orientation, dissection, and sampling of pancreaticoduodenectomy specimens for a more practical and accurate evaluation of pancreatic, distal common bile duct, and ampullary tumors","volume":"38","author":"Adsay NV","year":"2014","unstructured":"Adsay NV, Basturk O, Saka B, et al.. Whipple made simple for surgical pathologists: orientation, dissection, and sampling of pancreaticoduodenectomy specimens for a more practical and accurate evaluation of pancreatic, distal common bile duct, and ampullary tumors. Am J Surg Pathol. 2014, 38:480-93. 10.1097\/PAS.0000000000000165","journal-title":"Am J Surg Pathol"},{"key":"ref3","article-title":"Analysis of Whipple\u2019s resection specimens: a histopathological perspective","volume":"3","author":"Ibrahim SS","year":"2016","unstructured":"Ibrahim SS, Kumari MG. Analysis of Whipple\u2019s resection specimens: a histopathological perspective. Ann Pathol Lab Med. 2016, 3:106-12.","journal-title":"Ann Pathol Lab Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001763","article-title":"Multi-institutional validation study of the American Joint Commission on Cancer (8th edition) changes for T and N staging in patients with pancreatic adenocarcinoma","volume":"265","author":"Allen PJ","year":"2017","unstructured":"Allen PJ, Kuk D, Castillo CF, et al.. Multi-institutional validation study of the American Joint Commission on Cancer (8th edition) changes for T and N staging in patients with pancreatic adenocarcinoma. Ann Surg. 2017, 265:185-91. 10.1097\/SLA.0000000000001763","journal-title":"Ann Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000000712","article-title":"Single-incision versus multiple-incision thoracoscopic lobectomy and segmentectomy: a propensity-matched analysis","volume":"261","author":"Wang BY","year":"2015","unstructured":"Wang BY, Liu CY, Hsu PK, Shih CS, Liu CC. Single-incision versus multiple-incision thoracoscopic lobectomy and segmentectomy: a propensity-matched analysis. Ann Surg. 2015, 261:793-9. 10.1097\/SLA.0000000000000712","journal-title":"Ann Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1080\/13651820701646206","article-title":"Improved lymph node retrieval in Whipple specimens as a result of implementation of a new uncinate margin protocol","volume":"9","author":"Rowsell CH","year":"2007","unstructured":"Rowsell CH, Hanna S, Hsieh E, Law C, Khalifa MA. Improved lymph node retrieval in Whipple specimens as a result of implementation of a new uncinate margin protocol. HPB (Oxford). 2007, 9:388-91. 10.1080\/13651820701646206","journal-title":"HPB (Oxford)"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-017-6025-x","article-title":"8th edition of the AJCC cancer staging manual: pancreas and hepatobiliary cancers","volume":"25","author":"Chun YS","year":"2018","unstructured":"Chun YS, Pawlik TM, Vauthey JN. 8th edition of the AJCC cancer staging manual: pancreas and hepatobiliary cancers. Ann Surg Oncol. 2018, 25:845-7. 10.1245\/s10434-017-6025-x","journal-title":"Ann Surg Oncol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2020-236477","article-title":"Primary squamous cell carcinoma of the ampulla of Vater: management and review of the literature","volume":"14","author":"Soni S","year":"2021","unstructured":"Soni S, Elhence P, Varshney VK, Suman S. Primary squamous cell carcinoma of the ampulla of Vater: management and review of the literature. BMJ Case Rep. 2021, 14:e236477. 10.1136\/bcr-2020-236477","journal-title":"BMJ Case Rep"},{"key":"ref9","article-title":"Pathologic findings of Whipple pancreaticoduodenectomy: a 5-year review on 51 cases at Taleghani general hospital","volume":"5","author":"Foroughi F","year":"2012","unstructured":"Foroughi F, Mohsenifar Z, Ahmadvand A, Zare K. Pathologic findings of Whipple pancreaticoduodenectomy: a 5-year review on 51 cases at Taleghani general hospital. Gastroenterol Hepatol Bed Bench. 2012, 5:179-82.","journal-title":"Gastroenterol Hepatol Bed Bench"},{"key":"ref10","doi-asserted-by":"crossref","DOI":"10.31729\/jnma.2857","article-title":"Histopathologic analysis of pancreatoduodenectomy specimen","volume":"55","author":"Dhakhwa R","year":"2016","unstructured":"Dhakhwa R, Kafle N. Histopathologic analysis of pancreatoduodenectomy specimen. J Nepal Med Assoc. 2016, 55:79-85.","journal-title":"J Nepal Med Assoc"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12957-015-0498-5","article-title":"Distribution and pathological features of pancreatic, ampullary, biliary and duodenal cancers resected with pancreaticoduodenectomy","volume":"13","author":"Chandrasegaram MD","year":"2015","unstructured":"Chandrasegaram MD, Chiam SC, Chen JW, et al.. Distribution and pathological features of pancreatic, ampullary, biliary and duodenal cancers resected with pancreaticoduodenectomy. World J Surg Oncol. 2015, 13:85. 10.1186\/s12957-015-0498-5","journal-title":"World J Surg Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/hpb.12098","article-title":"Evaluation of a laparoscopic liver resection in the setting of cirrhosis","volume":"16","author":"Cannon RM","year":"2014","unstructured":"Cannon RM, Saggi B, Buell JF. Evaluation of a laparoscopic liver resection in the setting of cirrhosis. HPB (Oxford). 2014, 16:164-9. 10.1111\/hpb.12098","journal-title":"HPB (Oxford)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.12.020","article-title":"Borderline resectable pancreatic cancer: the importance of this emerging stage of disease","volume":"206","author":"Katz MH","year":"2008","unstructured":"Katz MH, Pisters PW, Evans DB, et al.. Borderline resectable pancreatic cancer: the importance of this emerging stage of disease. J Am Coll Surg. 2008, 206:833-46; discussion 846-8. 10.1016\/j.jamcollsurg.2007.12.020","journal-title":"J Am Coll Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1515\/pjs-2015-0011","article-title":"Benign histology after pancreaticoduodenectomy for suspected malignancy. Lessons to be learned- a single centre experience","volume":"87","author":"Wojcicki J","year":"2015","unstructured":"Wojcicki J, Zen Y, Peddu P, et al.. Benign histology after pancreaticoduodenectomy for suspected malignancy. Lessons to be learned- a single centre experience. Pol Przegl Chir. 2015, 87:6-15. 10.1515\/pjs-2015-0011","journal-title":"Pol Przegl Chir"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.9734\/jammr\/2022\/v34i143131","article-title":"Histopathological spectrum in Whipple\u2019s resection specimens-a six years retrospective study in a tertiary care centre","volume":"5","author":"Imam ZS","year":"2022","unstructured":"Imam ZS, Rabab S, Singh R, Kumar B, Mandal M, Singh RK, Haider MZ. Histopathological spectrum in Whipple\u2019s resection specimens-a six years retrospective study in a tertiary care centre. J Adv Med Med Res. 2022, 5:31-47. 10.9734\/jammr\/2022\/v34i143131","journal-title":"J Adv Med Med Res"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-022-09441-1","article-title":"Comparison of oncologic outcomes between pancreaticoduodenectomy and total pancreatectomy for pancreatic adenocarcinoma","volume":"37","author":"Zhu J","year":"2023","unstructured":"Zhu J, Jiang Z, Xie B, Fu C, Xiao W, Li Y. Comparison of oncologic outcomes between pancreaticoduodenectomy and total pancreatectomy for pancreatic adenocarcinoma. Surg Endosc. 2023, 37:109-19. 10.1007\/s00464-022-09441-1","journal-title":"Surg Endosc"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2023.e20238","article-title":"Utility of intraoperative pathology consultations of whipple resection specimens and their impact on final margin status","volume":"9","author":"Sina N","year":"2023","unstructured":"Sina N, Olkhov-Mitsel E, Chen L, et al.. Utility of intraoperative pathology consultations of whipple resection specimens and their impact on final margin status. Heliyon. 2023, 9:e20238. 10.1016\/j.heliyon.2023.e20238","journal-title":"Heliyon"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8664","article-title":"Impact of nationwide centralization of pancreaticoduodenectomy on hospital mortality","volume":"99","author":"de Wilde RF","year":"2012","unstructured":"de Wilde RF, Besselink MG, van der Tweel I, et al.. Impact of nationwide centralization of pancreaticoduodenectomy on hospital mortality. Br J Surg. 2012, 99:404-10. 10.1002\/bjs.8664","journal-title":"Br J Surg"},{"key":"ref19","article-title":"Assessment of risk factors for complications following Whipple operation","volume":"5","author":"Karichery M","year":"2023","unstructured":"Karichery M, Zacharia GS. Assessment of risk factors for complications following Whipple operation. Int J Acad Med Pharm. 2023, 5:434-8.","journal-title":"Int J Acad Med Pharm"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.surge.2010.10.011","article-title":"Postoperative pancreatic fistula","volume":"9","author":"Hackert T","year":"2011","unstructured":"Hackert T, Werner J, B\u00fcchler MW. Postoperative pancreatic fistula. Surgeon. 2011, 9:211-7. 10.1016\/j.surge.2010.10.011","journal-title":"Surgeon"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2016.11.014","article-title":"Ernational Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after","volume":"161","author":"Bassi C","year":"2017","unstructured":"Bassi C, Marchegiani G, Dervenis C, et al.. Ernational Study Group (ISGPS) definition and grading of postoperative pancreatic fistula: 11 years after. Surgery. 2017, 161:584-91. 10.1016\/j.surg.2016.11.014","journal-title":"Surgery"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000033808","article-title":"Surgical treatment of gastric stump carcinoma after Whipple procedure: a case report","volume":"102","author":"Xie W","year":"2023","unstructured":"Xie W, Liu K, Lai J, Li J. Surgical treatment of gastric stump carcinoma after Whipple procedure: a case report. Medicine (Baltimore). 2023, 102:e33808. 10.1097\/MD.0000000000033808","journal-title":"Medicine (Baltimore)"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2018.02.014","article-title":"Early postoperative and late metabolic morbidity after pancreatic resections: an old and new challenge for surgeons - a review","volume":"216","author":"Beger HG","year":"2018","unstructured":"Beger HG, Mayer B. Early postoperative and late metabolic morbidity after pancreatic resections: an old and new challenge for surgeons - a review. Am J Surg. 2018, 216:131-4. 10.1016\/j.amjsurg.2018.02.014","journal-title":"Am J Surg"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2024.110635","article-title":"Solid pseudopapillary neoplasm of the pancreas causing obstructive jaundice: case report of a rare entity","volume":"126","author":"Maity R","year":"2025","unstructured":"Maity R, Dhali A, Chattopadhyay PK, Biswas J, Dhali GK. Solid pseudopapillary neoplasm of the pancreas causing obstructive jaundice: case report of a rare entity. Int J Surg Case Rep. 2025, 126:110635. 10.1016\/j.ijscr.2024.110635","journal-title":"Int J Surg Case Rep"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1093\/bjs\/znad330","article-title":"Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries","volume":"111","author":"PancreasGroup.org Collaborative","year":"2024","unstructured":"PancreasGroup.org Collaborative. Pancreatic surgery outcomes: multicentre prospective snapshot study in 67 countries. Br J Surg. 2024, 111:znad330. 10.1093\/bjs\/znad330","journal-title":"Br J Surg"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000001869","article-title":"A multi-institutional comparison of perioperative outcomes of robotic and open pancreaticoduodenectomy","volume":"264","author":"Zureikat AH","year":"2016","unstructured":"Zureikat AH, Postlewait LM, Liu Y, et al.. A multi-institutional comparison of perioperative outcomes of robotic and open pancreaticoduodenectomy. Ann Surg. 2016, 264:640-9. 10.1097\/SLA.0000000000001869","journal-title":"Ann Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/350228-whipple-procedure-vs-distal-pancreatectomy-a-study-on-the-efficacy-survival-rates-and-complication-rates-in-patients-with-pancreatic-cancer","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,25]],"date-time":"2025-03-25T01:26:10Z","timestamp":1742865970000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/350228-whipple-procedure-vs-distal-pancreatectomy-a-study-on-the-efficacy-survival-rates-and-complication-rates-in-patients-with-pancreatic-cancer"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,24]]},"references-count":26,"URL":"https:\/\/doi.org\/10.7759\/cureus.81091","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,3,24]]}}}