{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,24]],"date-time":"2026-03-24T12:35:08Z","timestamp":1774355708427,"version":"3.50.1"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,8]]},"DOI":"10.7759\/cureus.81899","type":"journal-article","created":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T17:18:08Z","timestamp":1744132688000},"source":"Crossref","is-referenced-by-count":1,"title":["Atypical Presentation of Non-small Cell Lung Carcinoma"],"prefix":"10.7759","author":[{"given":"Ammaar","family":"Jan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oudhay S","family":"Sohal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Delaram","family":"Pourkalbassi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Desiree","family":"Boisson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nick","family":"Taylor","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lorena","family":"Rivera","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ernest","family":"Metelus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damian","family":"Casadesus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21492","article-title":"Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries","volume":"68","author":"Bray F","year":"2018","unstructured":"Bray F, Ferlay J, Soerjomataram I, Siegel RL, Torre LA, Jemal A. Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA Cancer J Clin. 2018, 68:394-424. 10.3322\/caac.21492","journal-title":"CA Cancer J Clin"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2021.4932","article-title":"Update of incidence, prevalence, survival, and initial treatment in patients with non-small cell lung cancer in the US","volume":"7","author":"Ganti AK","year":"2021","unstructured":"Ganti AK, Klein AB, Cotarla I, Seal B, Chou E. Update of incidence, prevalence, survival, and initial treatment in patients with non-small cell lung cancer in the US. JAMA Oncol. 2021, 7:1824-32. 10.1001\/jamaoncol.2021.4932","journal-title":"JAMA Oncol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2256","article-title":"What are the clinical symptoms and physical signs for non-small cell lung cancer before diagnosis is made? A nation-wide multicenter 10-year retrospective study in China","volume":"8","author":"Xing PY","year":"2019","unstructured":"Xing PY, Zhu YX, Wang L, et al.. What are the clinical symptoms and physical signs for non-small cell lung cancer before diagnosis is made? A nation-wide multicenter 10-year retrospective study in China. Cancer Med. 2019, 8:4055-69. 10.1002\/cam4.2256","journal-title":"Cancer Med"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159\/000506810","article-title":"Metastatic spread to the pituitary","volume":"110","author":"Shimon I","year":"2020","unstructured":"Shimon I. Metastatic spread to the pituitary. Neuroendocrinology. 2020, 110:805-8. 10.1159\/000506810","journal-title":"Neuroendocrinology"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.22608","article-title":"Lung cancer metastasis to the pituitary gland","volume":"14","author":"Kilbane Myers J","year":"2022","unstructured":"Kilbane Myers J, Abdelrahman A, Akpunonu B. Lung cancer metastasis to the pituitary gland. Cureus. 2022, 14:e22608. 10.7759\/cureus.22608","journal-title":"Cureus"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3390\/jcm4010075","article-title":"Malignant cardiac tamponade from non-small cell lung cancer: case series from the era of molecular targeted therapy","volume":"4","author":"Li BT","year":"2014","unstructured":"Li BT, Pearson A, Pavlakis N, et al.. Malignant cardiac tamponade from non-small cell lung cancer: case series from the era of molecular targeted therapy. J Clin Med. 2014, 4:75-84. 10.3390\/jcm4010075","journal-title":"J Clin Med"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.13762","article-title":"Lung adenocarcinoma presenting as malignant pericardial effusion\/tamponade","volume":"13","author":"Vemireddy LP","year":"2021","unstructured":"Vemireddy LP, Jain N, Aqeel A, Jeelani HM, Shayuk M. Lung adenocarcinoma presenting as malignant pericardial effusion\/tamponade. Cureus. 2021, 13:e13762. 10.7759\/cureus.13762","journal-title":"Cureus"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1378\/chest.12-2351","article-title":"Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines","volume":"143","author":"Gould MK","year":"2013","unstructured":"Gould MK, Donington J, Lynch WR, Mazzone PJ, Midthun DE, Naidich DP, Wiener RS. Evaluation of individuals with pulmonary nodules: when is it lung cancer? Diagnosis and management of lung cancer, 3rd ed: American College of Chest Physicians evidence-based clinical practice guidelines. Chest. 2013, 143:e93S-e120S. 10.1378\/chest.12-2351","journal-title":"Chest"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/nop\/npaf001","article-title":"Seizure risk factors and management approaches in patients with brain metastases [IN PRINT]","author":"Vaios EJ","year":"2025","unstructured":"Vaios EJ, Maingi S, Batich K, et al.. Seizure risk factors and management approaches in patients with brain metastases [IN PRINT]. Neuro-Oncology Practice. 2025, npaf001. 10.1093\/nop\/npaf001","journal-title":"Neuro-Oncology Practice"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-023-11733-1","article-title":"Clinical features and prognosis of cardiac metastatic tumors","volume":"23","author":"Lin Z","year":"2023","unstructured":"Lin Z, Xiao H, Liu J, et al.. Clinical features and prognosis of cardiac metastatic tumors. BMC Cancer. 2023, 23:1235. 10.1186\/s12885-023-11733-1","journal-title":"BMC Cancer"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-4070-x","article-title":"Metastatic cardiac tumors: from clinical presentation through diagnosis to treatment","volume":"18","author":"Burazor I","year":"2018","unstructured":"Burazor I, Aviel-Ronen S, Imazio M, et al.. Metastatic cardiac tumors: from clinical presentation through diagnosis to treatment. BMC Cancer. 2018, 18:202. 10.1186\/s12885-018-4070-x","journal-title":"BMC Cancer"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.16.16148","article-title":"Metastasis to the heart: a radiologic approach to diagnosis with pathologic correlation","volume":"207","author":"Lichtenberger JP 3rd","year":"2016","unstructured":"Lichtenberger JP 3rd, Reynolds DA, Keung J, Keung E, Carter BW. Metastasis to the heart: a radiologic approach to diagnosis with pathologic correlation. AJR Am J Roentgenol. 2016, 207:764-72. 10.2214\/AJR.16.16148","journal-title":"AJR Am J Roentgenol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1007\/s10147-015-0794-7","article-title":"Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients","volume":"20","author":"Takayama T","year":"2015","unstructured":"Takayama T, Okura Y, Okada Y, et al.. Characteristics of neoplastic cardiac tamponade and prognosis after pericardiocentesis: a single-center study of 113 consecutive cancer patients. Int J Clin Oncol. 2015, 20:872-7. 10.1007\/s10147-015-0794-7","journal-title":"Int J Clin Oncol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/s11102-020-01034-2","article-title":"Pituitary metastases: presentation and outcomes from a pituitary center over the last decade","volume":"23","author":"Lithgow K","year":"2020","unstructured":"Lithgow K, Siqueira I, Senthil L, et al.. Pituitary metastases: presentation and outcomes from a pituitary center over the last decade. Pituitary. 2020, 23:258-65. 10.1007\/s11102-020-01034-2","journal-title":"Pituitary"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2022.0025","article-title":"Non-small cell lung cancer, version 3.2022, NCCN clinical practice guidelines in oncology","volume":"20","author":"Ettinger DS","year":"2022","unstructured":"Ettinger DS, Wood DE, Aisner DL, et al.. Non-small cell lung cancer, version 3.2022, NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2022, 20:497-530. 10.6004\/jnccn.2022.0025","journal-title":"J Natl Compr Canc Netw"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/323259-atypical-presentation-of-non-small-cell-lung-carcinoma","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,8]],"date-time":"2025-04-08T17:18:09Z","timestamp":1744132689000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/323259-atypical-presentation-of-non-small-cell-lung-carcinoma"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,8]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.81899","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,8]]}}}