{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T04:19:45Z","timestamp":1744258785983,"version":"3.40.4"},"reference-count":64,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,9]]},"DOI":"10.7759\/cureus.81959","type":"journal-article","created":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T14:17:16Z","timestamp":1744208236000},"source":"Crossref","is-referenced-by-count":0,"title":["Assessing Morbidity and Outcomes of Posterior Lumbar Fusion in Elderly Patients: A Systematic Review and Meta-Analysis"],"prefix":"10.7759","author":[{"given":"Yeswanth","family":"Akula","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Srinath","family":"Pammi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sameer","family":"Rathore","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sonu","family":"Mehta","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pranshu","family":"Agrawal","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George W","family":"Monaghan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhanzhe","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ajay","family":"Asokan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maheswara","family":"Akula","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001161","article-title":"Minimally invasive versus open laminectomy for lumbar stenosis: a systematic review and meta-analysis","volume":"41","author":"Phan K","year":"2016","unstructured":"Phan K, Mobbs RJ. Minimally invasive versus open laminectomy for lumbar stenosis: a systematic review and meta-analysis. Spine (Phila Pa 1976). 2016, 41:E91-E100. 10.1097\/BRS.0000000000001161","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-010-1672-7","article-title":"Clinical features and surgical outcomes of cervical spondylotic myelopathy in patients aged 80 years or older: a multi-center retrospective study","volume":"20","author":"Nagashima H","year":"2011","unstructured":"Nagashima H, Dokai T, Hashiguchi H, et al.. Clinical features and surgical outcomes of cervical spondylotic myelopathy in patients aged 80 years or older: a multi-center retrospective study. Eur Spine J. 2011, 20:240-6. 10.1007\/s00586-010-1672-7","journal-title":"Eur Spine J"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2008.01771.x","article-title":"Complications and outcomes of lumbar spine surgery in elderly people: a review of the literature","volume":"56","author":"Cloyd JM","year":"2008","unstructured":"Cloyd JM, Acosta FL Jr, Ames CP. Complications and outcomes of lumbar spine surgery in elderly people: a review of the literature. J Am Geriatr Soc. 2008, 56:1318-27. 10.1111\/j.1532-5415.2008.01771.x","journal-title":"J Am Geriatr Soc"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0707136","article-title":"Surgical versus nonsurgical therapy for lumbar spinal stenosis","volume":"358","author":"Weinstein JN","year":"2008","unstructured":"Weinstein JN, Tosteson TD, Lurie JD, et al.. Surgical versus nonsurgical therapy for lumbar spinal stenosis. N Engl J Med. 2008, 358:794-810. 10.1056\/NEJMoa0707136","journal-title":"N Engl J Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-118-3-199302010-00011","article-title":"Hazards of hospitalization of the elderly","volume":"118","author":"Creditor MC","year":"1993","unstructured":"Creditor MC. Hazards of hospitalization of the elderly. Ann Intern Med. 1993, 118:219-23. 10.7326\/0003-4819-118-3-199302010-00011","journal-title":"Ann Intern Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1532-5415.2005.53159.x","article-title":"Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery","volume":"53","author":"Hamel MB","year":"2005","unstructured":"Hamel MB, Henderson WG, Khuri SF, Daley J. Surgical outcomes for patients aged 80 and older: morbidity and mortality from major noncardiac surgery. J Am Geriatr Soc. 2005, 53:424-9. 10.1111\/j.1532-5415.2005.53159.x","journal-title":"J Am Geriatr Soc"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.n160","article-title":"PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews","volume":"372","author":"Page MJ","year":"2021","unstructured":"Page MJ, Moher D, Bossuyt PM, et al.. PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021, 372:n160. 10.1136\/bmj.n160","journal-title":"BMJ"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2020.04.128","article-title":"How safe is minimally invasive transforaminal lumbar interbody fusion for octogenarians?: a perioperative complication analysis","volume":"139","author":"Vasilikos I","year":"2020","unstructured":"Vasilikos I, Fistouris P, Kr\u00fcger MT, et al.. How safe is minimally invasive transforaminal lumbar interbody fusion for octogenarians?: a perioperative complication analysis. World Neurosurg. 2020, 139:e754-60. 10.1016\/j.wneu.2020.04.128","journal-title":"World Neurosurg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2019.06.181","article-title":"Enhanced recovery after surgery (ERAS) for spine surgery: a systematic review","volume":"130","author":"Dietz N","year":"2019","unstructured":"Dietz N, Sharma M, Adams S, et al.. Enhanced recovery after surgery (ERAS) for spine surgery: a systematic review. World Neurosurg. 2019, 130:415-26. 10.1016\/j.wneu.2019.06.181","journal-title":"World Neurosurg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000002208","article-title":"90-day readmission after lumbar spinal fusion surgery in New York state between 2005 and 2014: a 10-year analysis of a statewide cohort","volume":"42","author":"Baaj AA","year":"2017","unstructured":"Baaj AA, Lang G, Hsu W-C, Avila MJ, Mao J, Sedrakyan A. 90-day readmission after lumbar spinal fusion surgery in New York state between 2005 and 2014: a 10-year analysis of a statewide cohort. Spine. 2017, 42:1706-16. 10.1097\/BRS.0000000000002208","journal-title":"Spine"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000004451","article-title":"Are octogenarians at higher risk of complications after elective lumbar spinal fusion surgery? Analysis of a cohort of 7880 patients from the kaiser permanente spine registry","volume":"47","author":"Kuo CC","year":"2022","unstructured":"Kuo CC, Royse KE, Prentice HA, Harris JE, Guppy KH. Are octogenarians at higher risk of complications after elective lumbar spinal fusion surgery? Analysis of a cohort of 7880 patients from the kaiser permanente spine registry. Spine (Phila Pa 1976). 2022, 47:1719-27. 10.1097\/BRS.0000000000004451","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.51.829","article-title":"Clinical outcomes and adverse events following transforaminal interbody fusion for lumbar degenerative spondylolisthesis in elderly patients","volume":"51","author":"Takahashi T","year":"2011","unstructured":"Takahashi T, Hanakita J, Minami M, et al.. Clinical outcomes and adverse events following transforaminal interbody fusion for lumbar degenerative spondylolisthesis in elderly patients. Neurol Med Chir (Tokyo). 2011, 51:829-35. 10.2176\/nmc.51.829","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1055\/s-0036-1578806","article-title":"Clinical outcomes of posterior lumbar interbody fusion for patients 80 years of age and older with lumbar degenerative disease: minimum 2 years' follow-up","volume":"6","author":"Hayashi K","year":"2016","unstructured":"Hayashi K, Matsumura A, Konishi S, Kato M, Namikawa T, Nakamura H. Clinical outcomes of posterior lumbar interbody fusion for patients 80 years of age and older with lumbar degenerative disease: minimum 2 years' follow-up. Global Spine J. 2016, 6:665-72. 10.1055\/s-0036-1578806","journal-title":"Global Spine J"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/0019-5413.201704","article-title":"Complication rate during multilevel lumbar fusion in patients above 60 years","volume":"51","author":"Mahesh B","year":"2017","unstructured":"Mahesh B, Upendra B, Vijay S, Kumar GA, Reddy S. Complication rate during multilevel lumbar fusion in patients above 60 years. Indian J Orthop. 2017, 51:139-46. 10.4103\/0019-5413.201704","journal-title":"Indian J Orthop"},{"key":"ref15","article-title":"Complications and clinical outcomes of minimally invasive transforaminal lumbar interbody fusion for the treatment of one- or two-level degenerative disc diseases of the lumbar spine in patients older than 65 years","volume":"125","author":"Wu WJ","year":"2012","unstructured":"Wu WJ, Liang Y, Zhang XK, Cao P, Zheng T. Complications and clinical outcomes of minimally invasive transforaminal lumbar interbody fusion for the treatment of one- or two-level degenerative disc diseases of the lumbar spine in patients older than 65 years . Chin Med J (Engl). 2012, 125:2505-10.","journal-title":"Chin Med J (Engl)"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.2176\/nmc.oa2012-0415","article-title":"Decompression only versus fusion surgery for lumbar stenosis in elderly patients over 75 years old: which is reasonable?","volume":"53","author":"Lee CH","year":"2013","unstructured":"Lee CH, Hyun SJ, Kim KJ, Jahng TA, Kim HJ. Decompression only versus fusion surgery for lumbar stenosis in elderly patients over 75 years old: which is reasonable?. Neurol Med Chir (Tokyo). 2013, 53:870-4. 10.2176\/nmc.oa2012-0415","journal-title":"Neurol Med Chir (Tokyo)"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_202307_33128","article-title":"Efficacy of minimally invasive transforaminal lumbar interbody fusion plus cement-augmented pedicle screw fixation in the treatment of degenerative lumbar spine disease with osteoporosis in the elderly","volume":"27","author":"Chen TZ","year":"2023","unstructured":"Chen TZ, Lu XJ, Wu DZ, Meng FF, Qin RJ. Efficacy of minimally invasive transforaminal lumbar interbody fusion plus cement-augmented pedicle screw fixation in the treatment of degenerative lumbar spine disease with osteoporosis in the elderly. Eur Rev Med Pharmacol Sci. 2023, 27:6573-82. 10.26355\/eurrev_202307_33128","journal-title":"Eur Rev Med Pharmacol Sci"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s11999-013-3411-y","article-title":"Elderly patients have similar outcomes compared to younger patients after minimally invasive surgery for spinal stenosis","volume":"472","author":"Aleem IS","year":"2014","unstructured":"Aleem IS, Rampersaud YR. Elderly patients have similar outcomes compared to younger patients after minimally invasive surgery for spinal stenosis. Clin Orthop Relat Res. 2014, 472:1824-30. 10.1007\/s11999-013-3411-y","journal-title":"Clin Orthop Relat Res"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1097\/CORR.0000000000001054","article-title":"Elderly patients undergoing minimally invasive transforaminal lumbar interbody fusion may have similar clinical outcomes, perioperative complications, and fusion rates as their younger counterparts","volume":"478","author":"Goh GS","year":"2020","unstructured":"Goh GS, Tay YW, Liow MH, et al.. Elderly patients undergoing minimally invasive transforaminal lumbar interbody fusion may have similar clinical outcomes, perioperative complications, and fusion rates as their younger counterparts. Clin Orthop Relat Res. 2020, 478:822-32. 10.1097\/CORR.0000000000001054","journal-title":"Clin Orthop Relat Res"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1186\/s13018-020-01814-3","article-title":"Enhanced recovery after surgery (ERAS) program for elderly patients with short-level lumbar fusion","volume":"15","author":"Wang P","year":"2020","unstructured":"Wang P, Wang Q, Kong C, et al.. Enhanced recovery after surgery (ERAS) program for elderly patients with short-level lumbar fusion. J Orthop Surg Res. 2020, 15:299. 10.1186\/s13018-020-01814-3","journal-title":"J Orthop Surg Res"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2474-12-189","article-title":"Instrumented intervertebral or posterolateral fusion in elderly patients: clinical results of a single center","volume":"12","author":"Endres S","year":"2011","unstructured":"Endres S, Aigner R, Wilke A. Instrumented intervertebral or posterolateral fusion in elderly patients: clinical results of a single center. BMC Musculoskelet Disord. 2011, 12:189. 10.1186\/1471-2474-12-189","journal-title":"BMC Musculoskelet Disord"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-011-1907-2","article-title":"Instrumented lumbar arthrodesis in elderly patients: prospective study using cannulated cemented pedicle screw instrumentation","volume":"20 Suppl 3","author":"Pi\u00f1era AR","year":"2011","unstructured":"Pi\u00f1era AR, Duran C, Lopez B, Saez I, Correia E, Alvarez L. Instrumented lumbar arthrodesis in elderly patients: prospective study using cannulated cemented pedicle screw instrumentation. Eur Spine J. 2011, 20 Suppl 3:408-14. 10.1007\/s00586-011-1907-2","journal-title":"Eur Spine J"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.3205\/000132","article-title":"Instrumented posterolateral fusion - clinical and functional outcome in elderly patients","volume":"9","author":"Endres S","year":"2011","unstructured":"Endres S. Instrumented posterolateral fusion - clinical and functional outcome in elderly patients. Ger Med Sci. 2011, 9:Doc09. 10.3205\/000132","journal-title":"Ger Med Sci"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-017-3555-6","article-title":"Is it safe to perform lumbar spine surgery on patients over eighty five?","volume":"41","author":"Bouloussa H","year":"2017","unstructured":"Bouloussa H, Alzakri A, Ghailane S, et al.. Is it safe to perform lumbar spine surgery on patients over eighty five?. Int Orthop. 2017, 41:2091-6. 10.1007\/s00264-017-3555-6","journal-title":"Int Orthop"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e31817e1022","article-title":"Life expectancy after lumbar spine surgery: one- to eleven-year follow-up of 1015 patients","volume":"33","author":"Kim HJ","year":"2008","unstructured":"Kim HJ, Lee HM, Kim HS, Moon ES, Park JO, Lee KJ, Moon SH. Life expectancy after lumbar spine surgery: one- to eleven-year follow-up of 1015 patients. Spine (Phila Pa 1976). 2008, 33:2116-23. 10.1097\/BRS.0b013e31817e1022","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3181c62294","article-title":"Life quality after instrumented lumbar fusion in the elderly","volume":"35","author":"Becker P","year":"2010","unstructured":"Becker P, Bretschneider W, Tuschel A, Ogon M. Life quality after instrumented lumbar fusion in the elderly. Spine (Phila Pa 1976). 2010, 35:1478-81. 10.1097\/BRS.0b013e3181c62294","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/s00586-012-2479-5","article-title":"Long-term health care utilisation and costs after spinal fusion in elderly patients","volume":"22","author":"Andersen T","year":"2013","unstructured":"Andersen T, B\u00fcnger C, S\u00f8gaard R. Long-term health care utilisation and costs after spinal fusion in elderly patients. Eur Spine J. 2013, 22:977-84. 10.1007\/s00586-012-2479-5","journal-title":"Eur Spine J"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1177\/21925682231214067","article-title":"Long-term results of minimally invasive transforaminal lumbar interbody fusion in elderly patients: a 5-year follow-up study","volume":"15","author":"Goh GS","year":"2025","unstructured":"Goh GS, Tay AY, Zeng GJ, Soh RC. Long-term results of minimally invasive transforaminal lumbar interbody fusion in elderly patients: a 5-year follow-up study. Global Spine J. 2025, 15:838-45. 10.1177\/21925682231214067","journal-title":"Global Spine J"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3928\/01477447-20120621-42","article-title":"Lumbar decompression and fusion in a centenarian","volume":"35","author":"Garcia RM","year":"2012","unstructured":"Garcia RM, Belding J, Bohlman HH. Lumbar decompression and fusion in a centenarian. Orthopedics. 2012, 35:e1141-4. 10.3928\/01477447-20120621-42","journal-title":"Orthopedics"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3340\/jkns.2010.48.5.412","article-title":"Lumbar interbody fusion outcomes in degenerative lumbar disease : comparison of results between patients over and under 65 years of age","volume":"48","author":"Jo DJ","year":"2010","unstructured":"Jo DJ, Jun JK, Kim KT, Kim SM. Lumbar interbody fusion outcomes in degenerative lumbar disease : comparison of results between patients over and under 65 years of age. J Korean Neurosurg Soc. 2010, 48:412-8. 10.3340\/jkns.2010.48.5.412","journal-title":"J Korean Neurosurg Soc"},{"key":"ref31","article-title":"Lumbar spinal fusion. A cohort study of complications, reoperations, and resource use in the Medicare population","volume":"18","author":"Deyo RA","year":"1993","unstructured":"Deyo RA, Ciol MA, Cherkin DC, Loeser JD, Bigos SJ. Lumbar spinal fusion. A cohort study of complications, reoperations, and resource use in the Medicare population. Spine (Phila Pa 1976). 1993, 18:1463-70.","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1007\/s00590-014-1556-3","article-title":"Lumbar spine surgery in patients 80 years of age or older: morbidity and mortality","volume":"25 Suppl 1","author":"Balabaud L","year":"2015","unstructured":"Balabaud L, Pitel S, Caux I, Dova C, Richard B, Antonietti P, Mazel C. Lumbar spine surgery in patients 80 years of age or older: morbidity and mortality. Eur J Orthop Surg Traumatol. 2015, 25 Suppl 1:S205-12. 10.1007\/s00590-014-1556-3","journal-title":"Eur J Orthop Surg Traumatol"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s00701-017-3384-9","article-title":"Medical complications and mortality in octogenarians undergoing elective spinal fusion surgeries","volume":"160","author":"Rajpal S","year":"2018","unstructured":"Rajpal S, Lee Nelson E, Villavicencio AT, Telang J, Kantha R, Beasley K, Burneikiene S. Medical complications and mortality in octogenarians undergoing elective spinal fusion surgeries. Acta Neurochir (Wien). 2018, 160:171-9. 10.1007\/s00701-017-3384-9","journal-title":"Acta Neurochir (Wien)"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0b013e3182098bfa","article-title":"Minimally invasive lumbar interbody fusion in patients older than 70 years of age: analysis of peri- and postoperative complications","volume":"68","author":"Karikari IO","year":"2011","unstructured":"Karikari IO, Grossi PM, Nimjee SM, et al.. Minimally invasive lumbar interbody fusion in patients older than 70 years of age: analysis of peri- and postoperative complications. Neurosurgery. 2011, 68:897-902. 10.1227\/NEU.0b013e3182098bfa","journal-title":"Neurosurgery"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1016\/j.otsr.2020.01.003","article-title":"Minimally invasive unilateral lumbar interbody fusion (UNILIF) in over-80-year-olds. Continuous series of 42 patients at 1.4 years' follow-up","volume":"106","author":"Ould-Slimane M","year":"2020","unstructured":"Ould-Slimane M, Cantogrel P, Lef\u00e8vre E, Parent HF, Gauth\u00e9 R. Minimally invasive unilateral lumbar interbody fusion (UNILIF) in over-80-year-olds. Continuous series of 42 patients at 1.4 years' follow-up. Orthop Traumatol Surg Res. 2020, 106:275-9. 10.1016\/j.otsr.2020.01.003","journal-title":"Orthop Traumatol Surg Res"},{"key":"ref36","article-title":"Multilevel spinal fusion in the aged: not a panacea","volume":"77","author":"R\u00f6llinghoff M","year":"2011","unstructured":"R\u00f6llinghoff M, Zarghooni K, Groos D, Siewe J, Eysel P, Sobottke R. Multilevel spinal fusion in the aged: not a panacea. Acta Orthop Belg. 2011, 77:97-102.","journal-title":"Acta Orthop Belg"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001364","article-title":"Patient-rated outcomes of lumbar fusion in patients with degenerative disease of the lumbar spine: does age matter?","volume":"41","author":"Marbacher S","year":"2016","unstructured":"Marbacher S, Mannion AF, Burkhardt JK, et al.. Patient-rated outcomes of lumbar fusion in patients with degenerative disease of the lumbar spine: does age matter?. Spine (Phila Pa 1976). 2016, 41:893-900. 10.1097\/BRS.0000000000001364","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1007\/s00264-018-3875-1","article-title":"Peri-operative complications of lumbar spine surgery in patients over eighty five years of age: a retrospective cohort study","volume":"42","author":"Onda S","year":"2018","unstructured":"Onda S, Kanayama M, Hashimoto T, Oha F, Iwata A, Tanaka M, Kaneko K. Peri-operative complications of lumbar spine surgery in patients over eighty five years of age: a retrospective cohort study. Int Orthop. 2018, 42:1083-9. 10.1007\/s00264-018-3875-1","journal-title":"Int Orthop"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2011.09.005","article-title":"Perioperative and postoperative complications of single-level minimally invasive transforaminal lumbar interbody fusion in elderly adults","volume":"19","author":"Lee P","year":"2012","unstructured":"Lee P, Fessler RG. Perioperative and postoperative complications of single-level minimally invasive transforaminal lumbar interbody fusion in elderly adults. J Clin Neurosci. 2012, 19:111-4. 10.1016\/j.jocn.2011.09.005","journal-title":"J Clin Neurosci"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.2106\/00004623-200311000-00004","article-title":"Perioperative complications of posterior lumbar decompression and arthrodesis in older adults","volume":"85","author":"Carreon LY","year":"2003","unstructured":"Carreon LY, Puno RM, Dimar JR 2nd, Glassman SD, Johnson JR. Perioperative complications of posterior lumbar decompression and arthrodesis in older adults. J Bone Joint Surg Am. 2003, 85:2089-92. 10.2106\/00004623-200311000-00004","journal-title":"J Bone Joint Surg Am"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.14444\/2022","article-title":"Posterior lumbar interbody fusion with instrumented posterolateral fusion in adult spondylolisthesis: description and association of clinico-surgical variables with prognosis in a series of 36 cases","volume":"9","author":"Lara-Almunia M","year":"2015","unstructured":"Lara-Almunia M, Gomez-Moreta JA, Hernandez-Vicente J. Posterior lumbar interbody fusion with instrumented posterolateral fusion in adult spondylolisthesis: description and association of clinico-surgical variables with prognosis in a series of 36 cases. Int J Spine Surg. 2015, 9:22. 10.14444\/2022","journal-title":"Int J Spine Surg"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/j.wneu.2016.03.052","article-title":"Postoperative complications for elderly patients after single-level lumbar fusions for spondylolisthesis","volume":"91","author":"Lieber BA","year":"2016","unstructured":"Lieber BA, Chiang V, Prabhu AV, et al.. Postoperative complications for elderly patients after single-level lumbar fusions for spondylolisthesis. World Neurosurg. 2016, 91:149-53. 10.1016\/j.wneu.2016.03.052","journal-title":"World Neurosurg"},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1186\/s12893-024-02356-9","article-title":"Predictors of achieving minimal clinically important difference in functional status for elderly patients with degenerative lumbar spinal stenosis undergoing lumbar decompression and fusion surgery","volume":"24","author":"Hou X","year":"2024","unstructured":"Hou X, Hu H, Cui P, Kong C, Wang W, Lu S. Predictors of achieving minimal clinically important difference in functional status for elderly patients with degenerative lumbar spinal stenosis undergoing lumbar decompression and fusion surgery. BMC Surg. 2024, 24:59. 10.1186\/s12893-024-02356-9","journal-title":"BMC Surg"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000251918.19508.b3","article-title":"Risk factors for the development of perioperative complications in elderly patients undergoing lumbar decompression and arthrodesis for spinal stenosis: an analysis of 166 patients","volume":"32","author":"Cassinelli EH","year":"2007","unstructured":"Cassinelli EH, Eubanks J, Vogt M, Furey C, Yoo J, Bohlman HH. Risk factors for the development of perioperative complications in elderly patients undergoing lumbar decompression and arthrodesis for spinal stenosis: an analysis of 166 patients. Spine (Phila Pa 1976). 2007, 32:230-5. 10.1097\/01.brs.0000251918.19508.b3","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.3171\/SPI\/2008\/9\/8\/137","article-title":"Single-level instrumented mini-open transforaminal lumbar interbody fusion in elderly patients","volume":"9","author":"Lee DY","year":"2008","unstructured":"Lee DY, Jung TG, Lee SH. Single-level instrumented mini-open transforaminal lumbar interbody fusion in elderly patients. J Neurosurg Spine. 2008, 9:137-44. 10.3171\/SPI\/2008\/9\/8\/137","journal-title":"J Neurosurg Spine"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1080\/17453670710014789","article-title":"Supplementary pedicle screw fixation in spinal fusion for degenerative spondylolisthesis in patients aged 65 and over: outcome after a minimum of 2 years follow-up in 82 patients","volume":"79","author":"Wu CH","year":"2008","unstructured":"Wu CH, Kao YH, Yang SC, Fu TS, Lai PL, Chen WJ. Supplementary pedicle screw fixation in spinal fusion for degenerative spondylolisthesis in patients aged 65 and over: outcome after a minimum of 2 years follow-up in 82 patients. Acta Orthop. 2008, 79:67-73. 10.1080\/17453670710014789","journal-title":"Acta Orthop"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-022-01756-w","article-title":"Surgical management of lumbar spinal stenosis in patients over 80: is there an increased risk?","volume":"45","author":"Rault F","year":"2022","unstructured":"Rault F, Briant AR, Kamga H, Gaberel T, Emery E. Surgical management of lumbar spinal stenosis in patients over 80: is there an increased risk?. Neurosurg Rev. 2022, 45:2385-99. 10.1007\/s10143-022-01756-w","journal-title":"Neurosurg Rev"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1016\/j.spinee.2017.08.250","article-title":"Surgical outcomes in the elderly with degenerative spondylolisthesis: comparative study between patients over 80 years of age and under 80 years-a gender-, diagnosis-, and surgical method-matched two-cohort analyses","volume":"18","author":"Liao JC","year":"2018","unstructured":"Liao JC, Chen WJ. Surgical outcomes in the elderly with degenerative spondylolisthesis: comparative study between patients over 80 years of age and under 80 years-a gender-, diagnosis-, and surgical method-matched two-cohort analyses. Spine J. 2018, 18:734-9. 10.1016\/j.spinee.2017.08.250","journal-title":"Spine J"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.F.00186","article-title":"Surgical outcomes of posterior lumbar interbody fusion in elderly patients","volume":"88","author":"Okuda S","year":"2006","unstructured":"Okuda S, Oda T, Miyauchi A, Haku T, Yamamoto T, Iwasaki M. Surgical outcomes of posterior lumbar interbody fusion in elderly patients. J Bone Joint Surg Am. 2006, 88:2714-20. 10.2106\/JBJS.F.00186","journal-title":"J Bone Joint Surg Am"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1093\/neuros\/nyz444","article-title":"The effect of older age on the perioperative outcomes of spinal fusion surgery in patients with lumbar degenerative disc disease with spondylolisthesis: a propensity score-matched analysis","volume":"87","author":"Badhiwala JH","year":"2020","unstructured":"Badhiwala JH, Karmur BS, Hachem LD, et al.. The effect of older age on the perioperative outcomes of spinal fusion surgery in patients with lumbar degenerative disc disease with spondylolisthesis: a propensity score-matched analysis. Neurosurgery. 2020, 87:672-8. 10.1093\/neuros\/nyz444","journal-title":"Neurosurgery"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S378327","article-title":"The impact of frailty on perioperative outcomes in patients receiving short-level posterior lumbar interbody fusion: a stepwise propensity score matching analysis","volume":"17","author":"Cui P","year":"2022","unstructured":"Cui P, Wang P, Wang J, Liu X, Kong C, Lu S. The impact of frailty on perioperative outcomes in patients receiving short-level posterior lumbar interbody fusion: a stepwise propensity score matching analysis. Clin Interv Aging. 2022, 17:1297-306. 10.2147\/CIA.S378327","journal-title":"Clin Interv Aging"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1097\/MD.0000000000038719","article-title":"The impact of instrumented lumbar fusion surgery on psychiatric problems in elderly patients with degenerative spinal stenosis: the observational study","volume":"103","author":"Choi WR","year":"2024","unstructured":"Choi WR, Ahn SM, Kim SH, Kim KY, Son HJ, Kang CN. The impact of instrumented lumbar fusion surgery on psychiatric problems in elderly patients with degenerative spinal stenosis: the observational study. Medicine (Baltimore). 2024, 103:e38719. 10.1097\/MD.0000000000038719","journal-title":"Medicine (Baltimore)"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.4103\/1011-4564.192818","article-title":"The incidences of perioperative complications in the elderly following minimally invasive lumbar transforaminal interbody fusion","volume":"36","author":"Yang YS","year":"2016","unstructured":"Yang YS, Hsieh CT, Lin JH, Chiang YH. The incidences of perioperative complications in the elderly following minimally invasive lumbar transforaminal interbody fusion. J Med Sci. 2016, 36:175-9. 10.4103\/1011-4564.192818","journal-title":"J Med Sci"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0b013e3182023796","article-title":"Lumbar fusion in octogenarians: the promise of minimally invasive surgery","volume":"35","author":"Rodgers WB","year":"2010","unstructured":"Rodgers WB, Gerber EJ, Rodgers JA. Lumbar fusion in octogenarians: the promise of minimally invasive surgery. Spine (Phila Pa 1976). 2010, 35:S355-60. 10.1097\/BRS.0b013e3182023796","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.21037\/jss.2019.03.06","article-title":"The prevalence of complications associated with lumbar and thoracic spinal deformity surgery in the elderly population: a meta-analysis","volume":"5","author":"Smith C","year":"2019","unstructured":"Smith C, Lamba N, Ou Z, et al.. The prevalence of complications associated with lumbar and thoracic spinal deformity surgery in the elderly population: a meta-analysis. J Spine Surg. 2019, 5:223-35. 10.21037\/jss.2019.03.06","journal-title":"J Spine Surg"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000953","article-title":"The aging of the global population: the changing epidemiology of disease and spinal disorders","volume":"77 Suppl 4","author":"Fehlings MG","year":"2015","unstructured":"Fehlings MG, Tetreault L, Nater A, et al.. The aging of the global population: the changing epidemiology of disease and spinal disorders. Neurosurgery. 2015, 77 Suppl 4:S1-5. 10.1227\/NEU.0000000000000953","journal-title":"Neurosurgery"},{"key":"ref57","unstructured":"World Bank Group. World Bank open data. (2025). Accessed: February 23, 2025: https:\/\/data.worldbank.org."},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000002822","article-title":"Trends in lumbar fusion procedure rates and associated hospital costs for degenerative spinal diseases in the United States, 2004 to 2015","volume":"44","author":"Martin BI","year":"2019","unstructured":"Martin BI, Mirza SK, Spina N, Spiker WR, Lawrence B, Brodke DS. Trends in lumbar fusion procedure rates and associated hospital costs for degenerative spinal diseases in the United States, 2004 to 2015. Spine (Phila Pa 1976). 2019, 44:369-76. 10.1097\/BRS.0000000000002822","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1097\/01.brs.0000192678.25586.e5","article-title":"Predicting morbidity and mortality of lumbar spine arthrodesis in patients in their ninth decade","volume":"31","author":"Raffo CS","year":"2006","unstructured":"Raffo CS, Lauerman WC. Predicting morbidity and mortality of lumbar spine arthrodesis in patients in their ninth decade. Spine (Phila Pa 1976). 2006, 31:99-103. 10.1097\/01.brs.0000192678.25586.e5","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1097\/01.BRS.0000048494.66599.DF","article-title":"Surgery of the lumbar spine for spinal stenosis in 118 patients 70 years of age or older","volume":"28","author":"Ragab AA","year":"2003","unstructured":"Ragab AA, Fye MA, Bohlman HH. Surgery of the lumbar spine for spinal stenosis in 118 patients 70 years of age or older. Spine (Phila Pa 1976). 2003, 28:348-53. 10.1097\/01.BRS.0000048494.66599.DF","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001025","article-title":"The incidence of durotomy and its clinical and economic impact in primary, short-segment lumbar fusion: an analysis of 17,232 cases","volume":"40","author":"Buck JS","year":"2015","unstructured":"Buck JS, Yoon ST. The incidence of durotomy and its clinical and economic impact in primary, short-segment lumbar fusion: an analysis of 17,232 cases. Spine (Phila Pa 1976). 2015, 40:1444-50. 10.1097\/BRS.0000000000001025","journal-title":"Spine (Phila Pa 1976)"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1227\/NEU.0000000000000943","article-title":"Management of degenerative lumbar spinal stenosis in the elderly","volume":"77 Suppl 4","author":"Shamji MF","year":"2015","unstructured":"Shamji MF, Mroz T, Hsu W, Chutkan N. Management of degenerative lumbar spinal stenosis in the elderly. Neurosurgery. 2015, 77 Suppl 4:S68-74. 10.1227\/NEU.0000000000000943","journal-title":"Neurosurgery"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.2106\/JBJS.H.00288","article-title":"Outcome of lumbar arthrodesis in patients sixty-five years of age or older","volume":"91","author":"Glassman SD","year":"2009","unstructured":"Glassman SD, Polly DW, Bono CM, Burkus K, Dimar JR. Outcome of lumbar arthrodesis in patients sixty-five years of age or older. J Bone Joint Surg Am. 2009, 91:783-90. 10.2106\/JBJS.H.00288","journal-title":"J Bone Joint Surg Am"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1097\/BRS.0000000000001188","article-title":"Patient-based surgical outcomes of posterior lumbar interbody fusion: patient satisfaction analysis","volume":"41","author":"Okuda S","year":"2016","unstructured":"Okuda S, Fujimori T, Oda T, et al.. Patient-based surgical outcomes of posterior lumbar interbody fusion: patient satisfaction analysis. Spine (Phila Pa 1976). 2016, 41:E148-54. 10.1097\/BRS.0000000000001188","journal-title":"Spine (Phila Pa 1976)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/347823-assessing-morbidity-and-outcomes-of-posterior-lumbar-fusion-in-elderly-patients-a-systematic-review-and-meta-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T14:17:21Z","timestamp":1744208241000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/347823-assessing-morbidity-and-outcomes-of-posterior-lumbar-fusion-in-elderly-patients-a-systematic-review-and-meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,9]]},"references-count":64,"URL":"https:\/\/doi.org\/10.7759\/cureus.81959","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,9]]}}}