{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,11]],"date-time":"2025-04-11T04:10:55Z","timestamp":1744344655932,"version":"3.40.4"},"reference-count":19,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,10]]},"DOI":"10.7759\/cureus.82001","type":"journal-article","created":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T12:46:24Z","timestamp":1744289184000},"source":"Crossref","is-referenced-by-count":0,"title":["Hidden Cancer as the Cause of an Ischemic Stroke: A Case Report"],"prefix":"10.7759","author":[{"given":"Yi-Hong","family":"Wu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tung-Chou","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"2023 Cause of Death Statistics. Ministry of Health and Welfare. (2024). Accessed. February 15, 2025: http:\/\/www.mohw.gov.tw\/cp-7162-79789-2.html."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2012.11.016","article-title":"Trends in cancer diagnoses among inpatients hospitalized with stroke","volume":"22","author":"Sanossian N","year":"2013","unstructured":"Sanossian N, Djabiras C, Mack WJ, Ovbiagele B. Trends in cancer diagnoses among inpatients hospitalized with stroke. J Stroke Cerebrovasc Dis. 2013, 22:1146-50. 10.1016\/j.jstrokecerebrovasdis.2012.11.016","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2015.02.006","article-title":"Predictors of occult cancer in acute ischemic stroke patients","volume":"24","author":"Cocho D","year":"2015","unstructured":"Cocho D, Gendre J, Boltes A, et al.. Predictors of occult cancer in acute ischemic stroke patients. J Stroke Cerebrovasc Dis. 2015, 24:1324-8. 10.1016\/j.jstrokecerebrovasdis.2015.02.006","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1159\/000440730","article-title":"Cancer-associated stroke: the Bergen NORSTROKE study","volume":"5","author":"Selvik HA","year":"2015","unstructured":"Selvik HA, Thomassen L, Bjerkreim AT, N\u00e6ss H. Cancer-associated stroke: the Bergen NORSTROKE study. Cerebrovasc Dis Extra. 2015, 5:107-13. 10.1159\/000440730","journal-title":"Cerebrovasc Dis Extra"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1177\/17562864221106362","article-title":"Cancer and stroke: commonly encountered by clinicians, but little evidence to guide clinical approach","volume":"15","author":"Woock M","year":"2022","unstructured":"Woock M, Martinez-Majander N, Seiffge DJ, et al.. Cancer and stroke: commonly encountered by clinicians, but little evidence to guide clinical approach. Ther Adv Neurol Disord. 2022, 15:10.1177\/17562864221106362","journal-title":"Ther Adv Neurol Disord"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2008.01.007","article-title":"First-ever stroke as initial presentation of systemic cancer","volume":"17","author":"Taccone FS","year":"2008","unstructured":"Taccone FS, Jeangette SM, Blecic SA. First-ever stroke as initial presentation of systemic cancer. J Stroke Cerebrovasc Dis. 2008, 17:169-74. 10.1016\/j.jstrokecerebrovasdis.2008.01.007","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1160\/TH16-08-0615","article-title":"Cancer-associated venous thromboembolism: Burden, mechanisms, and management","volume":"117","author":"Ay C","year":"2017","unstructured":"Ay C, Pabinger I, Cohen AT. Cancer-associated venous thromboembolism: Burden, mechanisms, and management. Thromb Haemost. 2017, 117:219-30. 10.1160\/TH16-08-0615","journal-title":"Thromb Haemost"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.112.658625","article-title":"Stroke and cancer: the importance of cancer-associated hypercoagulation as a possible stroke etiology","volume":"43","author":"Schwarzbach CJ","year":"2012","unstructured":"Schwarzbach CJ, Schaefer A, Ebert A, et al.. Stroke and cancer: the importance of cancer-associated hypercoagulation as a possible stroke etiology. Stroke. 2012, 43:3029-34. 10.1161\/STROKEAHA.112.658625","journal-title":"Stroke"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1177\/1747493020971104","article-title":"Frequency and predictors of occult cancer in ischemic stroke: a systematic review and meta-analysis","volume":"16","author":"Rioux B","year":"2021","unstructured":"Rioux B, Touma L, Nehme A, Gore G, Keezer MR, Gioia LC. Frequency and predictors of occult cancer in ischemic stroke: a systematic review and meta-analysis. Int J Stroke. 2021, 16:12-9. 10.1177\/1747493020971104","journal-title":"Int J Stroke"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0044959","article-title":"Clues to occult cancer in patients with ischemic stroke","volume":"7","author":"Kim SJ","year":"2012","unstructured":"Kim SJ, Park JH, Lee MJ, Park YG, Ahn MJ, Bang OY. Clues to occult cancer in patients with ischemic stroke. PLoS One. 2012, 7:e44959. 10.1371\/journal.pone.0044959","journal-title":"PLoS One"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1159\/000316764","article-title":"Acute stroke patients have occult malignancy more often than expected","volume":"64","author":"Uemura J","year":"2010","unstructured":"Uemura J, Kimura K, Sibazaki K, Inoue T, Iguchi Y, Yamashita S. Acute stroke patients have occult malignancy more often than expected. Eur Neurol. 2010, 64:140-4. 10.1159\/000316764","journal-title":"Eur Neurol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/ana.22050","article-title":"Coagulopathy and embolic signal in cancer patients with ischemic stroke","volume":"68","author":"Seok JM","year":"2010","unstructured":"Seok JM, Kim SG, Kim JW, Chung CS, Kim GM, Lee KH, Bang OY. Coagulopathy and embolic signal in cancer patients with ischemic stroke. Ann Neurol. 2010, 68:213-9. 10.1002\/ana.22050","journal-title":"Ann Neurol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1159\/000484668","article-title":"When to screen ischaemic stroke patients for cancer","volume":"45","author":"Selvik HA","year":"2018","unstructured":"Selvik HA, Bjerkreim AT, Thomassen L, Waje-Andreassen U, Naess H, Kvistad CE. When to screen ischaemic stroke patients for cancer. Cerebrovasc Dis. 2018, 45:42-7. 10.1159\/000484668","journal-title":"Cerebrovasc Dis"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2020.105366","article-title":"D-dimer and body CT to identify occult malignancy in acute ischemic stroke","volume":"29","author":"Rosenberg J","year":"2020","unstructured":"Rosenberg J, Do D, Cucchiara B, Mess\u00e9 SR. D-dimer and body CT to identify occult malignancy in acute ischemic stroke. J Stroke Cerebrovasc Dis. 2020, 29:105366. 10.1016\/j.jstrokecerebrovasdis.2020.105366","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.10.022","article-title":"Predictive value of plasma (D)-dimer levels for cancer-related stroke: a 3-year retrospective study","volume":"23","author":"Guo YJ","year":"2014","unstructured":"Guo YJ, Chang MH, Chen PL, Lee YS, Chang YC, Liao YC. Predictive value of plasma (D)-dimer levels for cancer-related stroke: a 3-year retrospective study. J Stroke Cerebrovasc Dis. 2014, 23:e249-54. 10.1016\/j.jstrokecerebrovasdis.2013.10.022","journal-title":"J Stroke Cerebrovasc Dis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1111\/ijs.12124","article-title":"Ischemic stroke in patients with cancer: is it different from usual strokes?","volume":"9","author":"Lee EJ","year":"2014","unstructured":"Lee EJ, Nah HW, Kwon JY, Kang DW, Kwon SU, Kim JS. Ischemic stroke in patients with cancer: is it different from usual strokes?. Int J Stroke. 2014, 9:406-12. 10.1111\/ijs.12124","journal-title":"Int J Stroke"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.5853\/jos.2020.00619","article-title":"Outcome of stroke patients with cancer and nonbacterial thrombotic endocarditis","volume":"22","author":"Yoo J","year":"2020","unstructured":"Yoo J, Choi JK, Kim YD, Nam HS, Park H, Lee HS, Heo JH. Outcome of stroke patients with cancer and nonbacterial thrombotic endocarditis. J Stroke. 2020, 22:245-53. 10.5853\/jos.2020.00619","journal-title":"J Stroke"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088283","article-title":"Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality","volume":"9","author":"Lau KK","year":"2014","unstructured":"Lau KK, Wong YK, Teo KC, et al.. Stroke patients with a past history of cancer are at increased risk of recurrent stroke and cardiovascular mortality. PLoS One. 2014, 9:e88283. 10.1371\/journal.pone.0088283","journal-title":"PLoS One"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14172","article-title":"Rivaroxaban versus aspirin for secondary prevention of ischaemic stroke in patients with cancer: a subgroup analysis of the NAVIGATE ESUS randomized trial","volume":"27","author":"Martinez-Majander N","year":"2020","unstructured":"Martinez-Majander N, Ntaios G, Liu YY, et al.. Rivaroxaban versus aspirin for secondary prevention of ischaemic stroke in patients with cancer: a subgroup analysis of the NAVIGATE ESUS randomized trial. Eur J Neurol. 2020, 27:841-8. 10.1111\/ene.14172","journal-title":"Eur J Neurol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/354041-hidden-cancer-as-the-cause-of-an-ischemic-stroke-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,10]],"date-time":"2025-04-10T12:46:26Z","timestamp":1744289186000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/354041-hidden-cancer-as-the-cause-of-an-ischemic-stroke-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,10]]},"references-count":19,"URL":"https:\/\/doi.org\/10.7759\/cureus.82001","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,10]]}}}