{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,15]],"date-time":"2025-04-15T04:01:20Z","timestamp":1744689680943,"version":"3.40.4"},"reference-count":13,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,14]]},"DOI":"10.7759\/cureus.82221","type":"journal-article","created":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T08:11:44Z","timestamp":1744618304000},"source":"Crossref","is-referenced-by-count":0,"title":["Diagnostic Challenges of Upper Gastrointestinal Tract Crohn\u2019s Disease"],"prefix":"10.7759","author":[{"given":"Sruthi","family":"Beladev","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Krupa A","family":"Joseph","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikhil Charles","family":"Madathiparambu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.121533","article-title":"Sleisenger and Fordtran\u2019s gastrointestinal and liver disease","volume":"56","author":"Adams DH","year":"2007","unstructured":"Adams DH. Sleisenger and Fordtran\u2019s gastrointestinal and liver disease. Gut. 2007, 56:1175. 10.1136\/gut.2007.121533","journal-title":"Gut"},{"key":"ref2","unstructured":"Montreal classification of inflammatory bowel disease [Internet]. (2023). https.\/\/radiopaedia.org\/articles\/montreal-classification-of-inflammatory-bowel-disease-2."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2021.105810","article-title":"Upper gastrointestinal tract involvement in Crohn\u2019s disease: a case report","volume":"81","author":"Orrell M","year":"2021","unstructured":"Orrell M, van 't Hullenaar C, Gosling J. Upper gastrointestinal tract involvement in Crohn\u2019s disease: a case report. Int J Surg Case Rep. 2021, 81:105810. 10.1016\/j.ijscr.2021.105810","journal-title":"Int J Surg Case Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/milmed\/usab517","article-title":"Upper gastrointestinal manifestations of Crohn\u2019s disease: differential diagnosis and treatment of an uncommon presentation of Crohn\u2019s disease","volume":"188","author":"Mehta K","year":"2021","unstructured":"Mehta K, Kurtz MT. Upper gastrointestinal manifestations of Crohn\u2019s disease: differential diagnosis and treatment of an uncommon presentation of Crohn\u2019s disease. Mil Med. 2021, 188:2750-4. 10.1093\/milmed\/usab517","journal-title":"Mil Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/PAP.0000000000000311","article-title":"Upper gastrointestinal tract involvement in inflammatory bowel diseases: histologic clues and pitfalls","volume":"29","author":"K\u0151v\u00e1ri B","year":"2022","unstructured":"K\u0151v\u00e1ri B, Pai RK. Upper gastrointestinal tract involvement in inflammatory bowel diseases: histologic clues and pitfalls. Adv Anat Pathol. 2022, 29:2-14. 10.1097\/PAP.0000000000000311","journal-title":"Adv Anat Pathol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjw168","article-title":"3rd European evidence-based consensus on the diagnosis and management of Crohn\u2019s disease 2016: part 1: diagnosis and medical management","volume":"11","author":"Gomoll\u00f3n F","year":"2017","unstructured":"Gomoll\u00f3n F, Dignass A, Annese V, et al.. 3rd European evidence-based consensus on the diagnosis and management of Crohn\u2019s disease 2016: part 1: diagnosis and medical management. J Crohns Colitis. 2017, 11:3-25. 10.1093\/ecco-jcc\/jjw168","journal-title":"J Crohns Colitis"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.4292\/wjgpt.v10.i2.35","article-title":"Crohn's disease of esophagus, stomach and duodenum","volume":"10","author":"Pimentel AM","year":"2019","unstructured":"Pimentel AM, Rocha R, Santana GO. Crohn's disease of esophagus, stomach and duodenum. World J Gastrointest Pharmacol Ther. 2019, 10:35-49. 10.4292\/wjgpt.v10.i2.35","journal-title":"World J Gastrointest Pharmacol Ther"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2072-0","article-title":"Upper gastrointestinal involvement of Crohn's disease: a prospective study on the role of upper endoscopy in the diagnostic work-up","volume":"57","author":"Annunziata ML","year":"2012","unstructured":"Annunziata ML, Caviglia R, Papparella LG, Cicala M. Upper gastrointestinal involvement of Crohn's disease: a prospective study on the role of upper endoscopy in the diagnostic work-up. Dig Dis Sci. 2012, 57:1618-23. 10.1007\/s10620-012-2072-0","journal-title":"Dig Dis Sci"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/bs.acc.2018.07.005","article-title":"Fecal calprotectin","volume":"87","author":"Ayling RM","year":"2018","unstructured":"Ayling RM, Kok K. Fecal calprotectin. Adv Clin Chem. 2018, 87:161-90. 10.1016\/bs.acc.2018.07.005","journal-title":"Adv Clin Chem"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/nu15051179","article-title":"Fecal calprotectin elevations associated with food intolerance\/malabsorption are significantly reduced with targeted diets","volume":"15","author":"Schnedl WJ","year":"2023","unstructured":"Schnedl WJ, Michaelis S, Enko D, Mangge H. Fecal calprotectin elevations associated with food intolerance\/malabsorption are significantly reduced with targeted diets. Nutrients. 2023, 15:10.3390\/nu15051179","journal-title":"Nutrients"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.13866","article-title":"Oral and upper gastrointestinal Crohn's disease","volume":"33","author":"Laube R","year":"2018","unstructured":"Laube R, Liu K, Schifter M, Yang JL, Suen MK, Leong RW. Oral and upper gastrointestinal Crohn's disease. J Gastroenterol Hepatol. 2018, 33:355-64. 10.1111\/jgh.13866","journal-title":"J Gastroenterol Hepatol"},{"key":"ref12","unstructured":"Role of diet in the development and management of Crohn\u2019s disease [Internet]. (2020). https.\/\/pubmed.ncbi.nlm.nih.gov\/32185530\/."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/crocol\/otad077","article-title":"Diet and nutrition in inflammatory bowel disease: a review of the literature","volume":"6","author":"Manski S","year":"2024","unstructured":"Manski S, Noverati N, Policarpo T, Rubin E, Shivashankar R. Diet and nutrition in inflammatory bowel disease: a review of the literature. Crohns Colitis 360. 2024, 6:1-10. 10.1093\/crocol\/otad077","journal-title":"Crohns Colitis 360"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/298697-diagnostic-challenges-of-upper-gastrointestinal-tract-crohns-disease","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,14]],"date-time":"2025-04-14T08:11:50Z","timestamp":1744618310000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/298697-diagnostic-challenges-of-upper-gastrointestinal-tract-crohns-disease"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,14]]},"references-count":13,"URL":"https:\/\/doi.org\/10.7759\/cureus.82221","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,14]]}}}