{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T04:21:03Z","timestamp":1745554863074,"version":"3.40.4"},"reference-count":18,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,24]]},"DOI":"10.7759\/cureus.82919","type":"journal-article","created":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T16:24:47Z","timestamp":1745511887000},"source":"Crossref","is-referenced-by-count":0,"title":["Intranasal Midazolam Prior to Enema for Management of Constipation in the Pediatric Emergency Department"],"prefix":"10.7759","author":[{"given":"Brian L","family":"Park","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emine","family":"Tunc","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pingping","family":"Qu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eileen","family":"Klein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Patrick","family":"Solari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2022.01.065 Full text linksCite","article-title":"Emergency department diagnosis and management of constipation in the United States, 2006-2017","volume":"54","author":"Zhou AZ","year":"2022","unstructured":"Zhou AZ, Lorenz D, Simon NJ, et al.. Emergency department diagnosis and management of constipation in the United States, 2006-2017. Am J Emerg Med. 2022, 54:91-96. 10.1016\/j.ajem.2022.01.065 Full text linksCite","journal-title":"Am J Emerg Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2015.03.016","article-title":"A multicenter study on childhood constipation and fecal incontinence: effects on quality of life","volume":"166","author":"Kovacic K","year":"2015","unstructured":"Kovacic K, Sood MR, Mugie S, et al.. A multicenter study on childhood constipation and fecal incontinence: effects on quality of life. J Pediatr. 2015, 166:1482-7.e1. 10.1016\/j.jpeds.2015.03.016","journal-title":"J Pediatr"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/MPG.0000000000000266","article-title":"Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN","volume":"58","author":"Tabbers MM","year":"2014","unstructured":"Tabbers MM, DiLorenzo C, Berger MY, et al.. Evaluation and treatment of functional constipation in infants and children: evidence-based recommendations from ESPGHAN and NASPGHAN. J Pediatr Gastroenterol Nutr. 2014, 58:258-74. 10.1097\/MPG.0000000000000266","journal-title":"J Pediatr Gastroenterol Nutr"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2021.09.006","article-title":"Intranasal fentanyl and midazolam use in children 3 years of age and younger in the emergency department","volume":"61","author":"Chang JG","year":"2021","unstructured":"Chang JG, Regen RB, Peravali R, et al.. Intranasal fentanyl and midazolam use in children 3 years of age and younger in the emergency department. J Emerg Med. 2021, 61:731-9. 10.1016\/j.jemermed.2021.09.006","journal-title":"J Emerg Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD009491.pub2","article-title":"Midazolam for sedation before procedures","volume":"2016","author":"Conway A","year":"2016","unstructured":"Conway A, Rolley J, Sutherland JR. Midazolam for sedation before procedures. Cochrane Database Syst Rev. 2016, 2016:CD009491. 10.1002\/14651858.CD009491.pub2","journal-title":"Cochrane Database Syst Rev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e31816ecb6f","article-title":"Atomized intranasal midazolam use for minor procedures in the pediatric emergency department","volume":"24","author":"Lane RD","year":"2008","unstructured":"Lane RD, Schunk JE. Atomized intranasal midazolam use for minor procedures in the pediatric emergency department. Pediatr Emerg Care. 2008, 24:300-3. 10.1097\/PEC.0b013e31816ecb6f","journal-title":"Pediatr Emerg Care"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2018.04.063","article-title":"Adverse events and satisfaction with use of intranasal midazolam for emergency department procedures in children","volume":"37","author":"Malia L","year":"2019","unstructured":"Malia L, Laurich VM, Sturm JJ. Adverse events and satisfaction with use of intranasal midazolam for emergency department procedures in children. Am J Emerg Med. 2019, 37:85-8. 10.1016\/j.ajem.2018.04.063","journal-title":"Am J Emerg Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jemermed.2017.05.029","article-title":"Evaluating clinical effectiveness and pharmacokinetic profile of atomized intranasal midazolam in children undergoing laceration repair","volume":"53","author":"Mellion SA","year":"2017","unstructured":"Mellion SA, Bourne D, Brou L, et al.. Evaluating clinical effectiveness and pharmacokinetic profile of atomized intranasal midazolam in children undergoing laceration repair. J Emerg Med. 2017, 53:397-404. 10.1016\/j.jemermed.2017.05.029","journal-title":"J Emerg Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2017.02.015","article-title":"When to pick the nose: out-of-hospital and emergency department intranasal administration of medications","volume":"70","author":"Rech MA","year":"2017","unstructured":"Rech MA, Barbas B, Chaney W, et al.. When to pick the nose: out-of-hospital and emergency department intranasal administration of medications. Ann Emerg Med. 2017, 70:203-11. 10.1016\/j.annemergmed.2017.02.015","journal-title":"Ann Emerg Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200009000-00016","article-title":"Midazolam: effects on amnesia and anxiety in children","volume":"93","author":"Kain ZN","year":"2000","unstructured":"Kain ZN, Hofstadter MB, Mayes LC, et al.. Midazolam: effects on amnesia and anxiety in children. Anesthesiology. 2000, 93:676-84. 10.1097\/00000542-200009000-00016","journal-title":"Anesthesiology"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2013.02.028","article-title":"Autism spectrum disorders in children with functional defecation disorders","volume":"163","author":"Peeters B","year":"2013","unstructured":"Peeters B, Noens I, Philips EM, et al.. Autism spectrum disorders in children with functional defecation disorders. J Pediatr. 2013, 163:873-8. 10.1016\/j.jpeds.2013.02.028","journal-title":"J Pediatr"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1469-8749.2010.03701.x","article-title":"Prevalence and clinical presentation of constipation in children with severe generalized cerebral palsy","volume":"52","author":"Veugelers R","year":"2010","unstructured":"Veugelers R, Benninga MA, Calis EA, et al.. Prevalence and clinical presentation of constipation in children with severe generalized cerebral palsy. Dev Med Child Neurol. 2010, 52:e216-21. 10.1111\/j.1469-8749.2010.03701.x","journal-title":"Dev Med Child Neurol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1177\/0962280211427759","article-title":"Extension of the modified Poisson regression model to prospective studies with correlated binary data","volume":"22","author":"Zou GY","year":"2013","unstructured":"Zou GY, Donner A. Extension of the modified Poisson regression model to prospective studies with correlated binary data. Stat Methods Med Res. 2013, 22:661-70. 10.1177\/0962280211427759","journal-title":"Stat Methods Med Res"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.18637\/jss.v015.i02","article-title":"The R package geepack for generalized estimating equations","volume":"15","author":"H\u00f8jsgaard S","year":"2005","unstructured":"H\u00f8jsgaard S, Halekoh U, Yan J. The R package geepack for generalized estimating equations. Jr Sta Sof. 2005, 15:1-11. 10.18637\/jss.v015.i02","journal-title":"Jr Sta Sof"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2021-052481","article-title":"Racial\/ethnic differences in ED opioid prescriptions for long bone fractures: trends over time","volume":"148","author":"Goyal MK","year":"2021","unstructured":"Goyal MK, Drendel AL, Chamberlain JM, et al.. Racial\/ethnic differences in ED opioid prescriptions for long bone fractures: trends over time. Pediatrics. 2021, 148:10.1542\/peds.2021-052481","journal-title":"Pediatrics"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s12887-021-02715-y","article-title":"Racial and ethnic disparities in opioid use for adolescents at US emergency departments","volume":"21","author":"Phan MT","year":"2021","unstructured":"Phan MT, Tomaszewski DM, Arbuckle C, et al.. Racial and ethnic disparities in opioid use for adolescents at US emergency departments. BMC Pediatr. 2021, 21:252. 10.1186\/s12887-021-02715-y","journal-title":"BMC Pediatr"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1111\/acem.14274","article-title":"Racial and ethnic disparities in bronchiolitis management in freestanding children's hospitals","volume":"28","author":"Honcoop AC","year":"2021","unstructured":"Honcoop AC, Poitevien P, Kerns E, et al.. Racial and ethnic disparities in bronchiolitis management in freestanding children's hospitals. Acad Emerg Med. 2021, 28:1043-50. 10.1111\/acem.14274","journal-title":"Acad Emerg Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0000000000002610","article-title":"Racial and ethnic differences in ondansetron use for acute gastroenteritis in children","volume":"38","author":"Dickerson-Young T","year":"2022","unstructured":"Dickerson-Young T, Uspal NG, Prince WB, et al.. Racial and ethnic differences in ondansetron use for acute gastroenteritis in children. Pediatr Emerg Care. 2022, 38:380-5. 10.1097\/PEC.0000000000002610","journal-title":"Pediatr Emerg Care"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/336342-intranasal-midazolam-prior-to-enema-for-management-of-constipation-in-the-pediatric-emergency-department","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,24]],"date-time":"2025-04-24T16:24:47Z","timestamp":1745511887000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/336342-intranasal-midazolam-prior-to-enema-for-management-of-constipation-in-the-pediatric-emergency-department"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,24]]},"references-count":18,"URL":"https:\/\/doi.org\/10.7759\/cureus.82919","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,24]]}}}