{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,21]],"date-time":"2025-11-21T18:24:31Z","timestamp":1763749471644,"version":"3.40.4"},"reference-count":30,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,4,25]]},"DOI":"10.7759\/cureus.83003","type":"journal-article","created":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T20:47:36Z","timestamp":1745614056000},"source":"Crossref","is-referenced-by-count":3,"title":["Radiosurgery to the Medial Thalamus for Chronic Pain: A Single Group Experience and Review of Literature"],"prefix":"10.7759","author":[{"given":"Paola","family":"Del Cid","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandra","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fidel","family":"Campos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claudia","family":"Cruz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alejandro","family":"Blanco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eduardo E","family":"Lovo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1080\/00325481.2019.1574403","article-title":"Reframing chronic pain as a disease, not a symptom: rationale and implications for pain management","volume":"131","author":"Clauw DJ","year":"2019","unstructured":"Clauw DJ, Essex MN, Pitman V, Jones KD. Reframing chronic pain as a disease, not a symptom: rationale and implications for pain management. Postgrad Med. 2019, 131:185-198. 10.1080\/00325481.2019.1574403","journal-title":"Postgrad Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s40122-022-00381-1","article-title":"Deep brain stimulation, stereotactic radiosurgery and high-intensity focused ultrasound targeting the limbic pain matrix: a comprehensive review","volume":"11","author":"N\u00fcssel M","year":"2022","unstructured":"N\u00fcssel M, Zhao Y, Knorr C, et al.. Deep brain stimulation, stereotactic radiosurgery and high-intensity focused ultrasound targeting the limbic pain matrix: a comprehensive review. Pain Ther. 2022, 11:459-476. 10.1007\/s40122-022-00381-1","journal-title":"Pain Ther"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/ons\/opx095","article-title":"Stereotactic radiosurgery for the treatment of chronic intractable pain: a systematic review","volume":"13","author":"Roberts DG","year":"2017","unstructured":"Roberts DG, Pouratian N. Stereotactic radiosurgery for the treatment of chronic intractable pain: a systematic review. Oper Neurosurg (Hagerstown). 2017, 13:543-551. 10.1093\/ons\/opx095","journal-title":"Oper Neurosurg (Hagerstown)"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(20)30233-7","article-title":"Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia","volume":"19","author":"Bendtsen L","year":"2020","unstructured":"Bendtsen L, Zakrzewska JM, Heinskou TB, et al.. Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia. Lancet Neurol. 2020, 19:784-796. 10.1016\/S1474-4422(20)30233-7","journal-title":"Lancet Neurol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-019-04825-x","article-title":"Assessing cancer pain - the first step toward improving patients' quality of life","volume":"27","author":"Minello C","year":"2019","unstructured":"Minello C, George B, Allano G, Maindet C, Burnod A, Lemaire A. Assessing cancer pain - the first step toward improving patients' quality of life. Support Care Cancer. 2019, 27:3095-3104. 10.1007\/s00520-019-04825-x","journal-title":"Support Care Cancer"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-013-0331-1","article-title":"Surgical\/radiological interventions for cancer pain","volume":"17","author":"Harsh V","year":"2013","unstructured":"Harsh V, Viswanathan A. Surgical\/radiological interventions for cancer pain. Curr Pain Headache Rep. 2013, 17:331. 10.1007\/s11916-013-0331-1","journal-title":"Curr Pain Headache Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.6421","article-title":"Stereotactic gamma ray radiosurgery to the centromedian and parafascicular complex of the thalamus for trigeminal neuralgia and other complex pain syndromes","volume":"11","author":"Lovo EE","year":"2019","unstructured":"Lovo EE, Torres B, Campos F, et al.. Stereotactic gamma ray radiosurgery to the centromedian and parafascicular complex of the thalamus for trigeminal neuralgia and other complex pain syndromes. Cureus. 2019, 11:e6421. 10.7759\/cureus.6421","journal-title":"Cureus"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2022.757241","article-title":"Pain and the triple network model","volume":"13","author":"De Ridder D","year":"2022","unstructured":"De Ridder D, Vanneste S, Smith M, Adhia D. Pain and the triple network model. Front Neurol. 2022, 13:757241. 10.3389\/fneur.2022.757241","journal-title":"Front Neurol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s10194-020-01198-z","article-title":"Burden of illness of trigeminal neuralgia among patients managed in a specialist center in England","volume":"21","author":"O'Callaghan L","year":"2020","unstructured":"O'Callaghan L, Floden L, Vinikoor-Imler L, Symonds T, Giblin K, Hartford C, Zakrzewska JM. Burden of illness of trigeminal neuralgia among patients managed in a specialist center in England. J Headache Pain. 2020, 21:130. 10.1186\/s10194-020-01198-z","journal-title":"J Headache Pain"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3171\/2018.7.GKS181583","article-title":"Medial Gamma Knife thalamotomy for intractable pain","volume":"129","author":"Urgosik D","year":"2018","unstructured":"Urgosik D, Liscak R. Medial Gamma Knife thalamotomy for intractable pain. J Neurosurg. 2018, 129:72-76. 10.3171\/2018.7.GKS181583","journal-title":"J Neurosurg"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1007\/s10143-021-01561-x","article-title":"Medial thalamotomy using stereotactic radiosurgery for intractable pain: a systematic review","volume":"45","author":"Franzini A","year":"2022","unstructured":"Franzini A, Rossini Z, Moosa S, et al.. Medial thalamotomy using stereotactic radiosurgery for intractable pain: a systematic review. Neurosurg Rev. 2022, 45:71-80. 10.1007\/s10143-021-01561-x","journal-title":"Neurosurg Rev"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines9070731","article-title":"Centromedian-parafascicular and somatosensory thalamic deep brain stimulation for treatment of chronic neuropathic pain: a contemporary series of 40 patients","volume":"9","author":"Abdallat M","year":"2021","unstructured":"Abdallat M, Saryyeva A, Blahak C, et al.. Centromedian-parafascicular and somatosensory thalamic deep brain stimulation for treatment of chronic neuropathic pain: a contemporary series of 40 patients. Biomedicines. 2021, 9:731. 10.3390\/biomedicines9070731","journal-title":"Biomedicines"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/braincomms\/fcad003","article-title":"The intralaminar thalamus: a review of its role as a target in functional neurosurgery","volume":"5","author":"Arnts H","year":"2023","unstructured":"Arnts H, Coolen SE, Fernandes FW, Schuurman R, Krauss JK, Groenewegen HJ, van den Munckhof P. The intralaminar thalamus: a review of its role as a target in functional neurosurgery. Brain Commun. 2023, 5:fcad003. 10.1093\/braincomms\/fcad003","journal-title":"Brain Commun"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7091-1376-9_19","article-title":"Radiosurgery as neuromodulation therapy!","volume":"116","author":"R\u00e9gis J","year":"2013","unstructured":"R\u00e9gis J. Radiosurgery as neuromodulation therapy!. Acta Neurochir Suppl. 2013, 116:121-126. 10.1007\/978-3-7091-1376-9_19","journal-title":"Acta Neurochir Suppl"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3171\/jns.2005.102.s_supplement.0276","article-title":"Gamma knife surgery for refractory postherpetic trigeminal neuralgia: targeting in one session both the retrogasserian trigeminal nerve and the centromedian nucleus of the thalamus","volume":"102","author":"Keep MF","year":"2005","unstructured":"Keep MF, DeMare PA, Ashby LS. Gamma knife surgery for refractory postherpetic trigeminal neuralgia: targeting in one session both the retrogasserian trigeminal nerve and the centromedian nucleus of the thalamus. J Neurosurg. 2005, 102:276-282. 10.3171\/jns.2005.102.s_supplement.0276","journal-title":"J Neurosurg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-030-69217-9_15","article-title":"Pituitary radiosurgery for management of intractable pain: Tokyo Women's Medical University experience and literature review","volume":"128","author":"Chernov MF","year":"2021","unstructured":"Chernov MF, Hayashi M. Pituitary radiosurgery for management of intractable pain: Tokyo Women's Medical University experience and literature review. Acta Neurochir Suppl. 2021, 128:133-144. 10.1007\/978-3-030-69217-9_15","journal-title":"Acta Neurochir Suppl"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.25430","article-title":"Radiomodulation in mixed, complex cancer pain by triple target irradiation in the brain: a preliminary experience","volume":"14","author":"Lovo EE","year":"2022","unstructured":"Lovo EE, Moreira A, Cruz C, et al.. Radiomodulation in mixed, complex cancer pain by triple target irradiation in the brain: a preliminary experience. Cureus. 2022, 14:e25430. 10.7759\/cureus.25430","journal-title":"Cureus"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1159\/000075108","article-title":"Role of pituitary radiosurgery for the management of intractable pain and potential future applications","volume":"81","author":"Hayashi M","year":"2004","unstructured":"Hayashi M, Taira T, Chernov M, et al.. Role of pituitary radiosurgery for the management of intractable pain and potential future applications. Stereotact Funct Neurosurg. 2004, 81:75-83. 10.1159\/000075108","journal-title":"Stereotact Funct Neurosurg"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.4811","article-title":"Automated stereotactic gamma ray radiosurgery to the pituitary gland in terminally ill cancer patients with opioid refractory pain","volume":"11","author":"Lovo EE","year":"2019","unstructured":"Lovo EE, Campos FJ, Caceros VE, Minervini M, Cruz CB, Arias JC, Reyes WA. Automated stereotactic gamma ray radiosurgery to the pituitary gland in terminally ill cancer patients with opioid refractory pain. Cureus. 2019, 11:e4811. 10.7759\/cureus.4811","journal-title":"Cureus"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.20971","article-title":"Radioneuromodulation by dual-target irradiation in pain crisis from trigeminal neuralgia","volume":"14","author":"Lovo EE","year":"2022","unstructured":"Lovo EE, Moreira A, Barahona KC, Caceros V, Cruz C, Arias J. Radioneuromodulation by dual-target irradiation in pain crisis from trigeminal neuralgia. Cureus. 2022, 14:e20971. 10.7759\/cureus.20971","journal-title":"Cureus"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.3171\/2020.4.JNS20558","article-title":"Gamma Knife central lateral thalamotomy for the treatment of neuropathic pain","volume":"135","author":"Franzini A","year":"2021","unstructured":"Franzini A, Attuati L, Zaed I, Moosa S, Stravato A, Navarria P, Picozzi P. Gamma Knife central lateral thalamotomy for the treatment of neuropathic pain. J Neurosurg. 2021, 135:228-236. 10.3171\/2020.4.JNS20558","journal-title":"J Neurosurg"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.14700","article-title":"Neuromodulation via focal radiation: radiomodulation update","volume":"13","author":"Schneider MB","year":"2021","unstructured":"Schneider MB, Walcott B, Adler JR Jr. Neuromodulation via focal radiation: radiomodulation update. Cureus. 2021, 13:e14700. 10.7759\/cureus.14700","journal-title":"Cureus"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.51602","article-title":"Dual-target radiosurgery for concomitant continuous pain presentation of trigeminal neuralgia: radiomodulation effect and dose","volume":"16","author":"Moreira A","year":"2024","unstructured":"Moreira A, Santos Hern\u00e1ndez DA, Caceros V, et al.. Dual-target radiosurgery for concomitant continuous pain presentation of trigeminal neuralgia: radiomodulation effect and dose. Cureus. 2024, 16:e51602. 10.7759\/cureus.51602","journal-title":"Cureus"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1227\/neu.0000000000002211","article-title":"Gamma knife central lateral thalamotomy for chronic neuropathic pain: a single-center, retrospective study","volume":"92","author":"Franzini A","year":"2023","unstructured":"Franzini A, Ninatti G, Rossini Z, et al.. Gamma knife central lateral thalamotomy for chronic neuropathic pain: a single-center, retrospective study. Neurosurgery. 2023, 92:363-369. 10.1227\/neu.0000000000002211","journal-title":"Neurosurgery"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.15194","article-title":"Gamma ray radiosurgery for trigeminal neuralgia: targeting proximal or distal to the dorsal root entry zone","volume":"13","author":"Lovo EE","year":"2021","unstructured":"Lovo EE, Moreira A, Barahona KC, et al.. Gamma ray radiosurgery for trigeminal neuralgia: targeting proximal or distal to the dorsal root entry zone. Cureus. 2021, 13:e15194. 10.7759\/cureus.15194","journal-title":"Cureus"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3171\/sup.2006.105.7.222","article-title":"Gamma Knife surgery targeting the centromedian nucleus of the thalamus for the palliative management of thalamic pain: durable response in stroke-induced thalamic pain syndrome","volume":"105","author":"Keep MF","year":"2006","unstructured":"Keep MF, Mastrofrancesco L, Craig AD, Ashby LS. Gamma Knife surgery targeting the centromedian nucleus of the thalamus for the palliative management of thalamic pain: durable response in stroke-induced thalamic pain syndrome. J Neurosurg. 2006, 105:222-228. 10.3171\/sup.2006.105.7.222","journal-title":"J Neurosurg"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.surneu.2003.08.033","article-title":"Linear accelerator thalamotomy","volume":"62","author":"Frighetto L","year":"2004","unstructured":"Frighetto L, De Salles A, Wallace R, Ford J, Selch M, Cabatan-Awang C, Solberg T. Linear accelerator thalamotomy. Surg Neurol. 2004, 62:106-113. 10.1016\/j.surneu.2003.08.033","journal-title":"Surg Neurol"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-7091-9371-6_22","article-title":"Medial thalamotomy with the Leksell Gamma Knife for treatment of chronic pain","volume":"62","author":"Young RF","year":"1994","unstructured":"Young RF, Jacques DS, Rand RW, Copcutt BR. Medial thalamotomy with the Leksell Gamma Knife for treatment of chronic pain. Acta Neurochir Suppl. 1994, 62:105-110. 10.1007\/978-3-7091-9371-6_22","journal-title":"Acta Neurochir Suppl"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1080\/01616412.1995.11740287","article-title":"Technique of stereotactic medial thalamotomy with the Leksell Gamma Knife for treatment of chronic pain","volume":"17","author":"Young RF","year":"1995","unstructured":"Young RF, Jacques DS, Rand RW, Copcutt BC, Vermeulen SS, Posewitz AE. Technique of stereotactic medial thalamotomy with the Leksell Gamma Knife for treatment of chronic pain. Neurol Res. 1995, 17:59-65. 10.1080\/01616412.1995.11740287","journal-title":"Neurol Res"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1007\/BF01402072","article-title":"Gammathalamotomy in intractable pain","volume":"52","author":"Steiner L","year":"1980","unstructured":"Steiner L, Forster D, Leksell L, Meyerson BA, Bo\u00ebthius J. Gammathalamotomy in intractable pain. Acta Neurochir (Wien). 1980, 52:173-184. 10.1007\/BF01402072","journal-title":"Acta Neurochir (Wien)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/351105-radiosurgery-to-the-medial-thalamus-for-chronic-pain-a-single-group-experience-and-review-of-literature","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,4,25]],"date-time":"2025-04-25T20:47:37Z","timestamp":1745614057000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/351105-radiosurgery-to-the-medial-thalamus-for-chronic-pain-a-single-group-experience-and-review-of-literature"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,4,25]]},"references-count":30,"URL":"https:\/\/doi.org\/10.7759\/cureus.83003","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,4,25]]}}}