{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T06:01:13Z","timestamp":1787032873298,"version":"build-2736575974"},"reference-count":16,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,7]]},"DOI":"10.7759\/cureus.83676","type":"journal-article","created":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T16:37:16Z","timestamp":1746635836000},"source":"Crossref","is-referenced-by-count":1,"title":["Povidone-Iodine as an Adjuvant Therapy for Refractory Gonorrhea Keratoconjunctivitis: A Case Report"],"prefix":"10.7759","author":[{"given":"Sinan","family":"Albear","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen","family":"LoBue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ayorinde","family":"Cooley","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Traeson","family":"Brandenburg","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rebecca","family":"Friedes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Park","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1038\/eye.2015.57","article-title":"Prevalence of gonococcal conjunctivitis in adults and neonates","volume":"29","author":"McAnena L","year":"2015","unstructured":"McAnena L, Knowles SJ, Curry A, Cassidy L. Prevalence of gonococcal conjunctivitis in adults and neonates. Eye (Lond). 2015, 29:875-80. 10.1038\/eye.2015.57","journal-title":"Eye (Lond)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(87)90095-6","article-title":"Gonococcal keratoconjunctivitis","volume":"32","author":"Ullman S","year":"1987","unstructured":"Ullman S, Roussel TJ, Forster RK. Gonococcal keratoconjunctivitis. Surv Ophthalmol. 1987, 32:199-208. 10.1016\/0039-6257(87)90095-6","journal-title":"Surv Ophthalmol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-9496-0_3","article-title":"Antimicrobial resistance in Neisseria gonorrhoeae and treatment of gonorrhea","author":"Unemo M","year":"2019","unstructured":"Unemo M, Golparian D, Eyre DW. Antimicrobial resistance in Neisseria gonorrhoeae and treatment of gonorrhea. Neisseria gonorrhoeae. Methods in Molecular Biology. Christodoulides M (ed): Humana, New York, NY; 2019. 10.1007\/978-1-4939-9496-0_3"},{"key":"ref4","article-title":"Action of povidone-iodine against methicillin-sensitive and -resistant cultures of Staphylococcus aureus","volume":"69","author":"Lacey RW","year":"1993","unstructured":"Lacey RW, Catto A. Action of povidone-iodine against methicillin-sensitive and -resistant cultures of Staphylococcus aureus. Postgrad Med J. 1993, 69:S78-83.","journal-title":"Postgrad Med J"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/ICU.0000000000000437","article-title":"The use of povidone-iodine in ophthalmology","volume":"29","author":"Grzybowski A","year":"2018","unstructured":"Grzybowski A, Kanclerz P, Myers WG. The use of povidone-iodine in ophthalmology. Curr Opin Ophthalmol. 2018, 29:19-32. 10.1097\/ICU.0000000000000437","journal-title":"Curr Opin Ophthalmol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0000000000002006","article-title":"Increasing povidone-iodine exposure in endothelial keratoplasty tissue processing and fungal infection impact","volume":"38","author":"Salisbury CD","year":"2019","unstructured":"Salisbury CD, Kirk CN, Lee WB, Hamilton SM, Kozarsky AM, Meinecke E, Stulting RD. Increasing povidone-iodine exposure in endothelial keratoplasty tissue processing and fungal infection impact. Cornea. 2019, 38:1093-6. 10.1097\/ICO.0000000000002006","journal-title":"Cornea"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200008033430507","article-title":"The red eye","volume":"343","author":"Leibowitz HM","year":"2000","unstructured":"Leibowitz HM. The red eye. N Engl J Med. 2000, 343:345-51. 10.1056\/NEJM200008033430507","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/sj.eye.6700112","article-title":"Gonococcal keratoconjunctivitis in adults","volume":"16","author":"Lee JS","year":"2002","unstructured":"Lee JS, Choi HY, Lee JE, Lee SH, Oum BS. Gonococcal keratoconjunctivitis in adults. Eye (Lond). 2002, 16:646-9. 10.1038\/sj.eye.6700112","journal-title":"Eye (Lond)"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9394(14)74560-x","article-title":"The sensitivity of Neisseria gonorrhoeae, Chlamydia trachomatis, and herpes simplex type II to disinfection with povidone-iodine","volume":"109","author":"Benevento WJ","year":"1990","unstructured":"Benevento WJ, Murray P, Reed CA, Pepose JS. The sensitivity of Neisseria gonorrhoeae, Chlamydia trachomatis, and herpes simplex type II to disinfection with povidone-iodine. Am J Ophthalmol. 1990, 109:329-33. 10.1016\/s0002-9394(14)74560-x","journal-title":"Am J Ophthalmol"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/bjo.87.12.1449","article-title":"A double application approach to ophthalmia neonatorum prophylaxis","volume":"87","author":"Isenberg SJ","year":"2003","unstructured":"Isenberg SJ, Apt L, Del Signore M, Gichuhi S, Berman NG. A double application approach to ophthalmia neonatorum prophylaxis. Br J Ophthalmol. 2003, 87:1449-52. 10.1136\/bjo.87.12.1449","journal-title":"Br J Ophthalmol"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmm049","article-title":"Prophylaxis of ophthalmia neonatorum comparison of betadine, erythromycin and no prophylaxis","volume":"53","author":"Ali Z","year":"2007","unstructured":"Ali Z, Khadije D, Elahe A, Mohammad M, Fateme Z, Narges Z. Prophylaxis of ophthalmia neonatorum comparison of betadine, erythromycin and no prophylaxis. J Trop Pediatr. 2007, 53:388-92. 10.1093\/tropej\/fmm049","journal-title":"J Trop Pediatr"},{"key":"ref12","article-title":"Update to CDC\u2019s sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections","volume":"61","author":"Centers for Disease Control and Prevention (CDC)","year":"2012","unstructured":"Centers for Disease Control and Prevention (CDC). Update to CDC\u2019s sexually transmitted diseases treatment guidelines, 2010: oral cephalosporins no longer a recommended treatment for gonococcal infections. MMWR Morb Mortal Wkly Rep. 2012, 61:590-4.","journal-title":"MMWR Morb Mortal Wkly Rep"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2013.12.001","article-title":"Povidone-iodine for endophthalmitis prophylaxis","volume":"157","author":"Ahmed Y","year":"2014","unstructured":"Ahmed Y, Scott IU, Pathengay A, Bawdekar A, Flynn HW Jr. Povidone-iodine for endophthalmitis prophylaxis. Am J Ophthalmol. 2014, 157:503-4. 10.1016\/j.ajo.2013.12.001","journal-title":"Am J Ophthalmol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2012.03.006","article-title":"Evidence-based guidelines for cataract surgery: guidelines based on data in the European Registry of Quality Outcomes for Cataract and Refractive Surgery database","volume":"38","author":"Lundstr\u00f6m M","year":"2012","unstructured":"Lundstr\u00f6m M, Barry P, Henry Y, Rosen P, Stenevi U. Evidence-based guidelines for cataract surgery: guidelines based on data in the European Registry of Quality Outcomes for Cataract and Refractive Surgery database. J Cataract Refract Surg. 2012, 38:1086-93. 10.1016\/j.jcrs.2012.03.006","journal-title":"J Cataract Refract Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.15.4.635-639.1982","article-title":"Increased bactericidal activity of dilute preparations of povidone-iodine solutions","volume":"15","author":"Berkelman RL","year":"1982","unstructured":"Berkelman RL, Holland BW, Anderson RL. Increased bactericidal activity of dilute preparations of povidone-iodine solutions. J Clin Microbiol. 1982, 15:635-9. 10.1128\/jcm.15.4.635-639.1982","journal-title":"J Clin Microbiol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrs.2010.11.028","article-title":"In vitro efficacy of a povidone-iodine 0.4% and dexamethasone 0.1% suspension against ocular pathogens","volume":"37","author":"Pelletier JS","year":"2011","unstructured":"Pelletier JS, Miller D, Liang B, Capriotti JA. In vitro efficacy of a povidone-iodine 0.4% and dexamethasone 0.1% suspension against ocular pathogens. J Cataract Refract Surg. 2011, 37:763-6. 10.1016\/j.jcrs.2010.11.028","journal-title":"J Cataract Refract Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/356138-povidone-iodine-as-an-adjuvant-therapy-for-refractory-gonorrhea-keratoconjunctivitis-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,7]],"date-time":"2025-05-07T16:37:17Z","timestamp":1746635837000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/356138-povidone-iodine-as-an-adjuvant-therapy-for-refractory-gonorrhea-keratoconjunctivitis-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,7]]},"references-count":16,"URL":"https:\/\/doi.org\/10.7759\/cureus.83676","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,7]]}}}