{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T09:10:06Z","timestamp":1746695406749,"version":"3.40.5"},"reference-count":10,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,8]]},"DOI":"10.7759\/cureus.83704","type":"journal-article","created":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T08:28:55Z","timestamp":1746692935000},"source":"Crossref","is-referenced-by-count":0,"title":["Optic Neuritis As the Initial Presentation of Syphilis"],"prefix":"10.7759","author":[{"given":"Bruno","family":"Bonito","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Joana","family":"Cartucho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Monica F","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"In\u00eas","family":"Ferreira Maia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria do Ros\u00e1rio","family":"Ginga","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2019-232520","article-title":"Neurosyphilis presenting as visually asymptomatic bilateral optic perineuritis","volume":"12","author":"Yosar J","year":"2019","unstructured":"Yosar J. Neurosyphilis presenting as visually asymptomatic bilateral optic perineuritis. BMJ Case Rep. 2019, 12:232520. 10.1136\/bcr-2019-232520","journal-title":"BMJ Case Rep"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1080\/08164622.2021.1906848","article-title":"Ocular syphilis","volume":"104","author":"Tsan GL","year":"2021","unstructured":"Tsan GL, Claiborne RT. Ocular syphilis. Clin Exp Optom. 2021, 104:756-9. 10.1080\/08164622.2021.1906848","journal-title":"Clin Exp Optom"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2013-008891","article-title":"Unilateral swollen optic disc: do not forget neurosyphilis","volume":"2013","author":"Porto L","year":"2013","unstructured":"Porto L, Capelo J, Carragoso A. Unilateral swollen optic disc: do not forget neurosyphilis. BMJ Case Rep. 2013, 2013:10.1136\/bcr-2013-008891","journal-title":"BMJ Case Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.800383","article-title":"An updated review of recent advances in neurosyphilis","volume":"9","author":"Zhou J","year":"2022","unstructured":"Zhou J, Zhang H, Tang K, Liu R, Li J. An updated review of recent advances in neurosyphilis. Front Med (Lausanne). 2022, 9:800383. 10.3389\/fmed.2022.800383","journal-title":"Front Med (Lausanne)"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/621872","article-title":"Neurosyphilis presenting as asymptomatic optic perineuritis","volume":"2012","author":"Parker SE","year":"2012","unstructured":"Parker SE, Pula JH. Neurosyphilis presenting as asymptomatic optic perineuritis. Case Rep Ophthalmol Med. 2012, 2012:621872. 10.1155\/2012\/621872","journal-title":"Case Rep Ophthalmol Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjo.2019.05.009","article-title":"Ocular syphilis: case series (2000-2015) from 2 tertiary care centres in Montreal, Canada","volume":"55","author":"Vadboncoeur J","year":"2020","unstructured":"Vadboncoeur J, Labb\u00e9 AC, Fortin C, et al.. Ocular syphilis: case series (2000-2015) from 2 tertiary care centres in Montreal, Canada. Can J Ophthalmol. 2020, 55:30-7. 10.1016\/j.jcjo.2019.05.009","journal-title":"Can J Ophthalmol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.910337","article-title":"Demographic, clinical and laboratory characteristics of ocular syphilis: 6-years case series study from an eye Center in East-China","volume":"13","author":"Sun CB","year":"2022","unstructured":"Sun CB, Liu GH, Wu R, Liu Z. Demographic, clinical and laboratory characteristics of ocular syphilis: 6-years case series study from an eye Center in East-China. Front Immunol. 2022, 13:910337. 10.3389\/fimmu.2022.910337","journal-title":"Front Immunol"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1111\/jdv.16347","article-title":"The importance of proper and prompt treatment of ocular syphilis: a lesson from permanent vision loss in 52 eyes","volume":"34","author":"Gu X","year":"2020","unstructured":"Gu X, Gao Y, Yan Y, et al.. The importance of proper and prompt treatment of ocular syphilis: a lesson from permanent vision loss in 52 eyes. J Eur Acad Dermatol Venereol. 2020, 34:1569-78. 10.1111\/jdv.16347","journal-title":"J Eur Acad Dermatol Venereol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.2004.020875","article-title":"Neurosyphilis with optic neuritis: an update","volume":"82","author":"Smith GT","year":"2006","unstructured":"Smith GT, Goldmeier D, Migdal C. Neurosyphilis with optic neuritis: an update. Postgrad Med J. 2006, 82:36-9. 10.1136\/pgmj.2004.020875","journal-title":"Postgrad Med J"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00080-24","article-title":"Could ceftriaxone be a viable alternative to penicillin for the treatment of ocular syphilis?","volume":"68","author":"Gu X","year":"2024","unstructured":"Gu X, Lu H, Yang Y, et al.. Could ceftriaxone be a viable alternative to penicillin for the treatment of ocular syphilis?. Antimicrob Agents Chemother. 2024, 68:e0008024. 10.1128\/aac.00080-24","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/360539-optic-neuritis-as-the-initial-presentation-of-syphilis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,8]],"date-time":"2025-05-08T08:28:55Z","timestamp":1746692935000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/360539-optic-neuritis-as-the-initial-presentation-of-syphilis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,8]]},"references-count":10,"URL":"https:\/\/doi.org\/10.7759\/cureus.83704","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,8]]}}}