{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T20:40:43Z","timestamp":1784752843470,"version":"3.55.0"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,8]]},"DOI":"10.7759\/cureus.83752","type":"journal-article","created":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:51:51Z","timestamp":1746751911000},"source":"Crossref","is-referenced-by-count":2,"title":["Comparative Effectiveness of High-Flow Nasal Cannula and Noninvasive Ventilation in Acute Hypoxemic Respiratory Failure: A Scoping Review"],"prefix":"10.7759","author":[{"given":"Viktor","family":"Kunder","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johnathon","family":"Harris","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dyese","family":"Moody","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1097\/01.CCM.0000057906.89552.8F","article-title":"Epidemiology and outcome of acute respiratory failure in intensive care unit patients","volume":"31","author":"Vincent JL","year":"2003","unstructured":"Vincent JL, Sakr Y, Ranieri VM. Epidemiology and outcome of acute respiratory failure in intensive care unit patients. Crit Care Med. 2003, 31:S296-S299. 10.1097\/01.CCM.0000057906.89552.8F","journal-title":"Crit Care Med"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2020.5394","article-title":"Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy","volume":"323","author":"Grasselli G","year":"2020","unstructured":"Grasselli G, Zangrillo A, Zanella A, et al.. Baseline characteristics and outcomes of 1591 patients infected with SARS-CoV-2 admitted to ICUs of the Lombardy region, Italy. JAMA. 2020, 323:1574-1581. 10.1001\/jama.2020.5394","journal-title":"JAMA"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000684","article-title":"The PANDORA study: prevalence and outcome of acute hypoxemic respiratory failure in the pre-COVID-19 era","volume":"4","author":"Villar J","year":"2022","unstructured":"Villar J, Mora-Ordo\u00f1ez JM, Soler JA, et al.. The PANDORA study: prevalence and outcome of acute hypoxemic respiratory failure in the pre-COVID-19 era. Crit Care Explor. 2022, 4:e0684. 10.1097\/CCE.0000000000000684","journal-title":"Crit Care Explor"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-024-07609-y","article-title":"Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study","volume":"50","author":"Ling RR","year":"2024","unstructured":"Ling RR, Ponnapa Reddy M, Subramaniam A, et al.. Epidemiology of acute hypoxaemic respiratory failure in Australian and New Zealand intensive care units during 2005-2022. A binational, registry-based study. Intensive Care Med. 2024, 50:1861-1872. 10.1007\/s00134-024-07609-y","journal-title":"Intensive Care Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa022450","article-title":"One-year outcomes in survivors of the acute respiratory distress syndrome","volume":"348","author":"Herridge MS","year":"2003","unstructured":"Herridge MS, Cheung AM, Tansey CM, et al.. One-year outcomes in survivors of the acute respiratory distress syndrome. N Engl J Med. 2003, 348:683-693. 10.1056\/NEJMoa022450","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/crj.13245","article-title":"Risk factors of unfavorable outcomes in chronic obstructive pulmonary disease patients treated with noninvasive ventilation for acute hypercapnic respiratory failure","volume":"14","author":"Gungor S","year":"2020","unstructured":"Gungor S, Mocin OY, Tuncay E, et al.. Risk factors of unfavorable outcomes in chronic obstructive pulmonary disease patients treated with noninvasive ventilation for acute hypercapnic respiratory failure. Clin Respir J. 2020, 14:1083-1089. 10.1111\/crj.13245","journal-title":"Clin Respir J"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.5664\/jcsm.3794","article-title":"Obstructive sleep apnea, obesity, and the development of acute respiratory distress syndrome","volume":"10","author":"Karnatovskaia LV","year":"2014","unstructured":"Karnatovskaia LV, Lee AS, Bender SP, Talmor D, Festic E. Obstructive sleep apnea, obesity, and the development of acute respiratory distress syndrome. J Clin Sleep Med. 2014, 10:657-662. 10.5664\/jcsm.3794","journal-title":"J Clin Sleep Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-020-03108-w","article-title":"Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study","volume":"24","author":"Ketcham SW","year":"2020","unstructured":"Ketcham SW, Sedhai YR, Miller HC, et al.. Causes and characteristics of death in patients with acute hypoxemic respiratory failure and acute respiratory distress syndrome: a retrospective cohort study. Crit Care. 2020, 24:391. 10.1186\/s13054-020-03108-w","journal-title":"Crit Care"},{"key":"ref9","article-title":"Ventilator complications","author":"Haribhai S","year":"2025","unstructured":"Haribhai S, Mahboobi SK. Ventilator complications. StatPearls Publishing, Treasure Island, FL; 2025."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.chest.2017.01.004","article-title":"Can high-flow nasal cannula reduce the rate of endotracheal intubation in adult patients with acute respiratory failure compared with conventional oxygen therapy and noninvasive positive pressure ventilation? A systematic review and meta-analysis","volume":"151","author":"Ni YN","year":"2017","unstructured":"Ni YN, Luo J, Yu H, et al.. Can high-flow nasal cannula reduce the rate of endotracheal intubation in adult patients with acute respiratory failure compared with conventional oxygen therapy and noninvasive positive pressure ventilation? A systematic review and meta-analysis. Chest. 2017, 151:764-775. 10.1016\/j.chest.2017.01.004","journal-title":"Chest"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2017.07.083","article-title":"The effect of high-flow nasal cannula in reducing the mortality and the rate of endotracheal intubation when used before mechanical ventilation compared with conventional oxygen therapy and noninvasive positive pressure ventilation. A systematic review and meta-analysis","volume":"36","author":"Ni YN","year":"2018","unstructured":"Ni YN, Luo J, Yu H, Liu D, Liang BM, Liang ZA. The effect of high-flow nasal cannula in reducing the mortality and the rate of endotracheal intubation when used before mechanical ventilation compared with conventional oxygen therapy and noninvasive positive pressure ventilation. A systematic review and meta-analysis. Am J Emerg Med. 2018, 36:226-233. 10.1016\/j.ajem.2017.07.083","journal-title":"Am J Emerg Med"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.5005\/jp-journals-10071-G23186","article-title":"ISCCM guidelines for the use of non-invasive ventilation in acute respiratory failure in adult ICUs","volume":"24","author":"Chawla R","year":"2020","unstructured":"Chawla R, Dixit SB, Zirpe KG, et al.. ISCCM guidelines for the use of non-invasive ventilation in acute respiratory failure in adult ICUs. Indian J Crit Care Med. 2020, 24:S61-S81. 10.5005\/jp-journals-10071-G23186","journal-title":"Indian J Crit Care Med"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/cc13103","article-title":"Non-invasive ventilation for acute hypoxemic respiratory failure: intubation rate and risk factors","volume":"17","author":"Thille AW","year":"2013","unstructured":"Thille AW, Contou D, Fragnoli C, C\u00f3rdoba-Izquierdo A, Boissier F, Brun-Buisson C. Non-invasive ventilation for acute hypoxemic respiratory failure: intubation rate and risk factors. Crit Care. 2013, 17:R269. 10.1186\/cc13103","journal-title":"Crit Care"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1136\/bmjspcare-2018-001672","article-title":"Assisted ventilation in motor neurone disease during inpatient palliative care: barriers and utilisation","volume":"10","author":"Gleeson A","year":"2020","unstructured":"Gleeson A, Johnson F. Assisted ventilation in motor neurone disease during inpatient palliative care: barriers and utilisation. BMJ Support Palliat Care. 2020, 10:358-362. 10.1136\/bmjspcare-2018-001672","journal-title":"BMJ Support Palliat Care"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1471-6712.2009.00740.x","article-title":"How to cope with the mask? Experiences of mask treatment in patients with acute chronic obstructive pulmonary disease-exacerbations","volume":"24","author":"Torheim H","year":"2010","unstructured":"Torheim H, Gjengedal E. How to cope with the mask? Experiences of mask treatment in patients with acute chronic obstructive pulmonary disease-exacerbations. Scand J Caring Sci. 2010, 24:499-506. 10.1111\/j.1471-6712.2009.00740.x","journal-title":"Scand J Caring Sci"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1186\/s13613-019-0608-6","article-title":"\"I had the feeling that I was trapped\": a bedside qualitative study of cognitive and affective attitudes toward noninvasive ventilation in patients with acute respiratory failure","volume":"9","author":"Iosifyan M","year":"2019","unstructured":"Iosifyan M, Schmidt M, Hurbault A, et al.. \"I had the feeling that I was trapped\": a bedside qualitative study of cognitive and affective attitudes toward noninvasive ventilation in patients with acute respiratory failure. Ann Intensive Care. 2019, 9:134. 10.1186\/s13613-019-0608-6","journal-title":"Ann Intensive Care"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0000000000002361","article-title":"Noninvasive ventilation in acute hypoxemic nonhypercapnic respiratory failure: a systematic review and meta-analysis","volume":"45","author":"Xu XP","year":"2017","unstructured":"Xu XP, Zhang XC, Hu SL, et al.. Noninvasive ventilation in acute hypoxemic nonhypercapnic respiratory failure: a systematic review and meta-analysis. Crit Care Med. 2017, 45:e727-e733. 10.1097\/CCM.0000000000002361","journal-title":"Crit Care Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1503326","article-title":"High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure","volume":"372","author":"Frat JP","year":"2015","unstructured":"Frat JP, Thille AW, Mercat A, et al.. High-flow oxygen through nasal cannula in acute hypoxemic respiratory failure. N Engl J Med. 2015, 372:2185-2196. 10.1056\/NEJMoa1503326","journal-title":"N Engl J Med"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4187\/respcare.09130","article-title":"Comparison of high-flow nasal cannula and noninvasive ventilation in acute hypoxemic respiratory failure due to severe COVID-19 pneumonia","volume":"66","author":"Nair PR","year":"2021","unstructured":"Nair PR, Haritha D, Behera S, et al.. Comparison of high-flow nasal cannula and noninvasive ventilation in acute hypoxemic respiratory failure due to severe COVID-19 pneumonia. Respir Care. 2021, 66:1824-1830. 10.4187\/respcare.09130","journal-title":"Respir Care"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000123","article-title":"Pediatric sepsis definition-a systematic review protocol by the pediatric sepsis definition taskforce","volume":"2","author":"Menon K","year":"2020","unstructured":"Menon K, Schlapbach LJ, Akech S, et al.. Pediatric sepsis definition-a systematic review protocol by the pediatric sepsis definition taskforce. Crit Care Explor. 2020, 2:e0123. 10.1097\/CCE.0000000000000123","journal-title":"Crit Care Explor"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.resp.2022.103842","article-title":"Noninvasive ventilation and high-flow nasal cannula in patients with acute hypoxemic respiratory failure by covid-19: a retrospective study of the feasibility, safety and outcomes","volume":"298","author":"Costa WN","year":"2022","unstructured":"Costa WN, Miguel JP, Prado FD, Lula LH, Amarante GA, Righetti RF, Yamaguti WP. Noninvasive ventilation and high-flow nasal cannula in patients with acute hypoxemic respiratory failure by covid-19: a retrospective study of the feasibility, safety and outcomes. Respir Physiol Neurobiol. 2022, 298:103842. 10.1016\/j.resp.2022.103842","journal-title":"Respir Physiol Neurobiol"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-022-03905-5","article-title":"Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study","volume":"26","author":"Wendel-Garcia PD","year":"2022","unstructured":"Wendel-Garcia PD, Mas A, Gonz\u00e1lez-Isern C, et al.. Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study. Crit Care. 2022, 26:37. 10.1186\/s13054-022-03905-5","journal-title":"Crit Care"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1186\/s12873-021-00402-w","article-title":"Comparison of hypoxemia, intubation procedure, and complications for non-invasive ventilation against high-flow nasal cannula oxygen therapy for patients with acute hypoxemic respiratory failure: a non-randomized retrospective analysis for effectiveness and safety (NIVaHIC-aHRF)","volume":"21","author":"Zhang C","year":"2021","unstructured":"Zhang C, Ou M. Comparison of hypoxemia, intubation procedure, and complications for non-invasive ventilation against high-flow nasal cannula oxygen therapy for patients with acute hypoxemic respiratory failure: a non-randomized retrospective analysis for effectiveness and safety (NIVaHIC-aHRF). BMC Emerg Med. 2021, 21:6. 10.1186\/s12873-021-00402-w","journal-title":"BMC Emerg Med"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.45798","article-title":"Comparison of high flow nasal cannula and continuous positive airway pressure in COVID-19 patients with acute respiratory distress syndrome in critical care unit: a randomized control study","volume":"15","author":"Mirunalini G","year":"2023","unstructured":"Mirunalini G, Anand K, Pushparani A, Kadirvelu G. Comparison of high flow nasal cannula and continuous positive airway pressure in COVID-19 patients with acute respiratory distress syndrome in critical care unit: a randomized control study. Cureus. 2023, 15:e45798. 10.7759\/cureus.45798","journal-title":"Cureus"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.3390\/medicina60010071","article-title":"Stratification of COVID-19 patients with moderate-to-severe hypoxemic respiratory failure for response to high-flow nasal cannula: a retrospective observational study","volume":"60","author":"Bagnato G","year":"2023","unstructured":"Bagnato G, Imbalzano E, Ioppolo C, et al.. Stratification of COVID-19 patients with moderate-to-severe hypoxemic respiratory failure for response to high-flow nasal cannula: a retrospective observational study. Medicina (Kaunas). 2023, 60:128. 10.3390\/medicina60010071","journal-title":"Medicina (Kaunas)"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S206567","article-title":"High flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study","volume":"14","author":"Sun J","year":"2019","unstructured":"Sun J, Li Y, Ling B, et al.. High flow nasal cannula oxygen therapy versus non-invasive ventilation for chronic obstructive pulmonary disease with acute-moderate hypercapnic respiratory failure: an observational cohort study. Int J Chron Obstruct Pulmon Dis. 2019, 14:1229-1237. 10.2147\/COPD.S206567","journal-title":"Int J Chron Obstruct Pulmon Dis"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.65709","article-title":"The use of high-flow nasal cannula in the emergency department and a comparison of its efficacy with noninvasive ventilation","volume":"16","author":"Shinde V","year":"2024","unstructured":"Shinde V, Mavudelli SJ. The use of high-flow nasal cannula in the emergency department and a comparison of its efficacy with noninvasive ventilation. Cureus. 2024, 16:e65709. 10.7759\/cureus.65709","journal-title":"Cureus"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2253-14-66","article-title":"Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV)","volume":"14","author":"Schwabbauer N","year":"2014","unstructured":"Schwabbauer N, Berg B, Blumenstock G, Haap M, Hetzel J, Riessen R. Nasal high-flow oxygen therapy in patients with hypoxic respiratory failure: effect on functional and subjective respiratory parameters compared to conventional oxygen therapy and non-invasive ventilation (NIV). BMC Anesthesiol. 2014, 14:66. 10.1186\/1471-2253-14-66","journal-title":"BMC Anesthesiol"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3390\/medicina58060769","article-title":"Predictors of noninvasive respiratory support failure in COVID-19 patients: a prospective observational study","volume":"58","author":"Zablockis R","year":"2022","unstructured":"Zablockis R, \u0160lekyt\u0117 G, Mere\u0161kevi\u010dien\u0117 R, K\u0117velaitien\u0117 K, Zablockien\u0117 B, Danila E. Predictors of noninvasive respiratory support failure in COVID-19 patients: a prospective observational study. Medicina (Kaunas). 2022, 58:769. 10.3390\/medicina58060769","journal-title":"Medicina (Kaunas)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/363831-comparative-effectiveness-of-high-flow-nasal-cannula-and-noninvasive-ventilation-in-acute-hypoxemic-respiratory-failure-a-scoping-review","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,9]],"date-time":"2025-05-09T00:51:52Z","timestamp":1746751912000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/363831-comparative-effectiveness-of-high-flow-nasal-cannula-and-noninvasive-ventilation-in-acute-hypoxemic-respiratory-failure-a-scoping-review"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,8]]},"references-count":29,"URL":"https:\/\/doi.org\/10.7759\/cureus.83752","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,8]]}}}