{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,4]],"date-time":"2026-09-04T03:39:43Z","timestamp":1788493183463,"version":"build-2803163510"},"reference-count":28,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,15]]},"DOI":"10.7759\/cureus.84151","type":"journal-article","created":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T07:32:06Z","timestamp":1747294326000},"source":"Crossref","is-referenced-by-count":2,"title":["Accuracy Assessment of Customized Titanium Plates Compared to 3D-Printed Splints in Le Fort I Osteotomy: A Randomized Clinical Trial Evaluating Clinical and Radiographic Outcomes"],"prefix":"10.7759","author":[{"given":"Abdelkareem M","family":"Abdelhamid","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Atef M","family":"Hassan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wael A","family":"El-Mohandes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2020.08.014","article-title":"Impact of orthognathic surgery on quality of life of patients with dentofacial deformity: a systematic review and meta-analysis","volume":"59","author":"Meger MN","year":"2021","unstructured":"Meger MN, Fatturi AL, Gerber JT, Weiss SG, Rocha JS, Scariot R, Wambier LM. Impact of orthognathic surgery on quality of life of patients with dentofacial deformity: a systematic review and meta-analysis. Br J Oral Maxillofac Surg. 2021, 59:265-71. 10.1016\/j.bjoms.2020.08.014","journal-title":"Br J Oral Maxillofac Surg"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2009.06.030","article-title":"Computer planning and intraoperative navigation in orthognathic surgery","volume":"69","author":"Bell RB","year":"2011","unstructured":"Bell RB. Computer planning and intraoperative navigation in orthognathic surgery. J Oral Maxillofac Surg. 2011, 69:592-605. 10.1016\/j.joms.2009.06.030","journal-title":"J Oral Maxillofac Surg"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2006.10.005","article-title":"Accuracy of the computer-aided surgical simulation (CASS) system in the treatment of patients with complex craniomaxillofacial deformity: a pilot study","volume":"65","author":"Xia JJ","year":"2007","unstructured":"Xia JJ, Gateno J, Teichgraeber JF, Christensen AM, Lasky RE, Lemoine JJ, Liebschner MA. Accuracy of the computer-aided surgical simulation (CASS) system in the treatment of patients with complex craniomaxillofacial deformity: a pilot study. J Oral Maxillofac Surg. 2007, 65:248-54. 10.1016\/j.joms.2006.10.005","journal-title":"J Oral Maxillofac Surg"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e3181f3c6a8","article-title":"Simulation-guided navigation: a new approach to improve intraoperative three-dimensional reproducibility during orthognathic surgery","volume":"21","author":"Mazzoni S","year":"2010","unstructured":"Mazzoni S, Badiali G, Lancellotti L, Babbi L, Bianchi A, Marchetti C. Simulation-guided navigation: a new approach to improve intraoperative three-dimensional reproducibility during orthognathic surgery. J Craniofac Surg. 2010, 21:1698-705. 10.1097\/SCS.0b013e3181f3c6a8","journal-title":"J Craniofac Surg"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2011.12.017","article-title":"Computer-aided design and computer-aided manufacturing locating guides accompanied with prebent titanium plates in orthognathic surgery","volume":"70","author":"Bai S","year":"2012","unstructured":"Bai S, Shang H, Liu Y, Zhao J, Zhao Y. Computer-aided design and computer-aided manufacturing locating guides accompanied with prebent titanium plates in orthognathic surgery. J Oral Maxillofac Surg. 2012, 70:2419-26. 10.1016\/j.joms.2011.12.017","journal-title":"J Oral Maxillofac Surg"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.07.007","article-title":"A paradigm shift in orthognathic surgery? A comparison of navigation, computer-aided designed\/computer-aided manufactured splints, and \"classic\" intermaxillary splints to surgical transfer of virtual orthognathic planning","volume":"71","author":"Zinser MJ","year":"2013","unstructured":"Zinser MJ, Sailer HF, Ritter L, Braumann B, Maegele M, Z\u00f6ller JE. A paradigm shift in orthognathic surgery? A comparison of navigation, computer-aided designed\/computer-aided manufactured splints, and \"classic\" intermaxillary splints to surgical transfer of virtual orthognathic planning. J Oral Maxillofac Surg. 2013, 71:2151.e1-21. 10.1016\/j.joms.2013.07.007","journal-title":"J Oral Maxillofac Surg"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/s0278-2391(99)90633-x","article-title":"Bimaxillary surgery using an intermediate splint to position the maxilla","volume":"57","author":"Ellis E 3rd","year":"1999","unstructured":"Ellis E 3rd. Bimaxillary surgery using an intermediate splint to position the maxilla. J Oral Maxillofac Surg. 1999, 57:53-6. 10.1016\/s0278-2391(99)90633-x","journal-title":"J Oral Maxillofac Surg"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2009.06.009","article-title":"Virtual model surgery and wafer fabrication for orthognathic surgery","volume":"38","author":"Choi JY","year":"2009","unstructured":"Choi JY, Song KG, Baek SH. Virtual model surgery and wafer fabrication for orthognathic surgery. Int J Oral Maxillofac Surg. 2009, 38:1306-10. 10.1016\/j.ijom.2009.06.009","journal-title":"Int J Oral Maxillofac Surg"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/SCS.0b013e31829a80d9","article-title":"Accuracy of upper jaw positioning with intermediate splint fabrication after virtual planning in bimaxillary orthognathic surgery","volume":"24","author":"Sun Y","year":"2013","unstructured":"Sun Y, Luebbers HT, Agbaje JO, Schepers S, Vrielinck L, Lambrichts I, Politis C. Accuracy of upper jaw positioning with intermediate splint fabrication after virtual planning in bimaxillary orthognathic surgery. J Craniofac Surg. 2013, 24:1871-6. 10.1097\/SCS.0b013e31829a80d9","journal-title":"J Craniofac Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2013.06.213","article-title":"Short- and long-term changes of condylar position after bilateral sagittal split ramus osteotomy for mandibular advancement in combination with Le Fort I osteotomy evaluated by cone-beam computed tomography","volume":"71","author":"Chen S","year":"2013","unstructured":"Chen S, Lei J, Wang X, Fu KY, Farzad P, Yi B. Short- and long-term changes of condylar position after bilateral sagittal split ramus osteotomy for mandibular advancement in combination with Le Fort I osteotomy evaluated by cone-beam computed tomography. J Oral Maxillofac Surg. 2013, 71:1956-66. 10.1016\/j.joms.2013.06.213","journal-title":"J Oral Maxillofac Surg"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2018.10.012","article-title":"Toward a higher accuracy in orthognathic surgery by using intraoperative computer navigation, 3D surgical guides, and\/or customized osteosynthesis plates: a systematic review","volume":"46","author":"Van den Bempt M","year":"2018","unstructured":"Van den Bempt M, Liebregts J, Maal T, Berg\u00e9 S, Xi T. Toward a higher accuracy in orthognathic surgery by using intraoperative computer navigation, 3D surgical guides, and\/or customized osteosynthesis plates: a systematic review. J Craniomaxillofac Surg. 2018, 46:2108-19. 10.1016\/j.jcms.2018.10.012","journal-title":"J Craniomaxillofac Surg"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2017.01.004","article-title":"Surgical navigation: a systematic review of indications, treatments, and outcomes in oral and maxillofacial surgery","volume":"75","author":"Azarmehr I","year":"2017","unstructured":"Azarmehr I, Stokbro K, Bell RB, Thygesen T. Surgical navigation: a systematic review of indications, treatments, and outcomes in oral and maxillofacial surgery. J Oral Maxillofac Surg. 2017, 75:1987-2005. 10.1016\/j.joms.2017.01.004","journal-title":"J Oral Maxillofac Surg"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2017.06.027","article-title":"Clinical accuracy of waferless maxillary positioning using customized surgical guides and patient specific osteosynthesis in bimaxillary orthognathic surgery","volume":"45","author":"Heufelder M","year":"2017","unstructured":"Heufelder M, Wilde F, Pietzka S, Mascha F, Winter K, Schramm A, Rana M. Clinical accuracy of waferless maxillary positioning using customized surgical guides and patient specific osteosynthesis in bimaxillary orthognathic surgery. J Craniomaxillofac Surg. 2017, 45:1578-85. 10.1016\/j.jcms.2017.06.027","journal-title":"J Craniomaxillofac Surg"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-025-03635-5","article-title":"CONSORT 2025 statement: updated guideline for reporting randomized trials","author":"Hopewell S","year":"2025","unstructured":"Hopewell S, Chan AW, Collins GS, et al.. CONSORT 2025 statement: updated guideline for reporting randomized trials. Nat Med. 2025, 10.1038\/s41591-025-03635-5","journal-title":"Nat Med"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2020.11.008","article-title":"Accuracy of splint vs splintless technique for virtually planned orthognathic surgery: A voxel-based three-dimensional analysis","volume":"49","author":"Karanxha L","year":"2021","unstructured":"Karanxha L, Rossi D, Hamanaka R, et al.. Accuracy of splint vs splintless technique for virtually planned orthognathic surgery: A voxel-based three-dimensional analysis. J Craniomaxillofac Surg. 2021, 49:1-8. 10.1016\/j.jcms.2020.11.008","journal-title":"J Craniomaxillofac Surg"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4103\/0253-7176.116232","article-title":"How to calculate sample size for different study designs in medical research?","volume":"35","author":"Charan J","year":"2013","unstructured":"Charan J, Biswas T. How to calculate sample size for different study designs in medical research?. Indian J Psychol Med. 2013, 35:121-6. 10.4103\/0253-7176.116232","journal-title":"Indian J Psychol Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/0278-2391(90)90532-7","article-title":"Accuracy of model surgery: evaluation of an old technique and introduction of a new one","volume":"48","author":"Ellis E 3rd","year":"1990","unstructured":"Ellis E 3rd. Accuracy of model surgery: evaluation of an old technique and introduction of a new one. J Oral Maxillofac Surg. 1990, 48:1161-7. 10.1016\/0278-2391(90)90532-7","journal-title":"J Oral Maxillofac Surg"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2011.11.009","article-title":"Computer-assisted orthognathic surgery: feasibility study using multiple CAD\/CAM surgical splints","volume":"113","author":"Zinser MJ","year":"2012","unstructured":"Zinser MJ, Mischkowski RA, Sailer HF, Z\u00f6ller JE. Computer-assisted orthognathic surgery: feasibility study using multiple CAD\/CAM surgical splints. Oral Surg Oral Med Oral Pathol Oral Radiol. 2012, 113:673-87. 10.1016\/j.oooo.2011.11.009","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.21608\/EDJ.2019.72225","article-title":"Computer guided maxillary positioning using osteotomy\/plates locating surgical guides in management of maxillary deficiency","volume":"65","author":"Askar N","year":"2019","unstructured":"Askar N, Omara M. Computer guided maxillary positioning using osteotomy\/plates locating surgical guides in management of maxillary deficiency. Egypt Dent J. 2019, 65:2103-13. 10.21608\/EDJ.2019.72225","journal-title":"Egypt Dent J"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.tripleo.2010.05.052","article-title":"CAD\/CAM surface templates as an alternative to the intermediate wafer in orthognathic surgery","volume":"110","author":"Bai S","year":"2010","unstructured":"Bai S, Bo B, Bi Y, et al.. CAD\/CAM surface templates as an alternative to the intermediate wafer in orthognathic surgery. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010, 110:e1-7. 10.1016\/j.tripleo.2010.05.052","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjoms.2013.03.007","article-title":"A novel method of computer aided orthognathic surgery using individual CAD\/CAM templates: a combination of osteotomy and repositioning guides","volume":"51","author":"Li B","year":"2013","unstructured":"Li B, Zhang L, Sun H, Yuan J, Shen SG, Wang X. A novel method of computer aided orthognathic surgery using individual CAD\/CAM templates: a combination of osteotomy and repositioning guides. Br J Oral Maxillofac Surg. 2013, 51:e239-44. 10.1016\/j.bjoms.2013.03.007","journal-title":"Br J Oral Maxillofac Surg"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1007\/s11548-015-1223-0","article-title":"Development of customized positioning guides using computer-aided design and manufacturing technology for orthognathic surgery","volume":"10","author":"Lin HH","year":"2015","unstructured":"Lin HH, Chang HW, Lo LJ. Development of customized positioning guides using computer-aided design and manufacturing technology for orthognathic surgery. Int J Comput Assist Radiol Surg. 2015, 10:2021-33. 10.1007\/s11548-015-1223-0","journal-title":"Int J Comput Assist Radiol Surg"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.joms.2016.01.016","article-title":"Custom-machined miniplates and bone-supported guides for orthognathic surgery: a new surgical procedure","volume":"74","author":"Brunso J","year":"2016","unstructured":"Brunso J, Franco M, Constantinescu T, Barbier L, Santamar\u00eda JA, Alvarez J. Custom-machined miniplates and bone-supported guides for orthognathic surgery: a new surgical procedure. J Oral Maxillofac Surg. 2016, 74:1061.e1-1061.e12. 10.1016\/j.joms.2016.01.016","journal-title":"J Oral Maxillofac Surg"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2014.10.024","article-title":"Patient specific implants (PSI) in reconstruction of orbital floor and wall fractures","volume":"43","author":"Gander T","year":"2015","unstructured":"Gander T, Essig H, Metzler P, Lindhorst D, Dubois L, R\u00fccker M, Schumann P. Patient specific implants (PSI) in reconstruction of orbital floor and wall fractures. J Craniomaxillofac Surg. 2015, 43:126-30. 10.1016\/j.jcms.2014.10.024","journal-title":"J Craniomaxillofac Surg"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2016.09.008","article-title":"The use of patient-specific implants in orthognathic surgery: a series of 32 maxillary osteotomy patients","volume":"44","author":"Suojanen J","year":"2016","unstructured":"Suojanen J, Leikola J, Stoor P. The use of patient-specific implants in orthognathic surgery: a series of 32 maxillary osteotomy patients. J Craniomaxillofac Surg. 2016, 44:1913-6. 10.1016\/j.jcms.2016.09.008","journal-title":"J Craniomaxillofac Surg"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0093402","article-title":"Comparison of the accuracy of voxel based registration and surface based registration for 3D assessment of surgical change following orthognathic surgery","volume":"9","author":"Almukhtar A","year":"2014","unstructured":"Almukhtar A, Ju X, Khambay B, McDonald J, Ayoub A. Comparison of the accuracy of voxel based registration and surface based registration for 3D assessment of surgical change following orthognathic surgery. PLoS One. 2014, 9:e93402. 10.1371\/journal.pone.0093402","journal-title":"PLoS One"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijom.2019.08.005","article-title":"Splintless surgery using patient-specific osteosynthesis in Le Fort I osteotomies: a randomized controlled multi-centre trial","volume":"49","author":"Kraeima J","year":"2020","unstructured":"Kraeima J, Schepers RH, Spijkervet FK, Maal TJ, Baan F, Witjes MJ, Jansma J. Splintless surgery using patient-specific osteosynthesis in Le Fort I osteotomies: a randomized controlled multi-centre trial. Int J Oral Maxillofac Surg. 2020, 49:454-60. 10.1016\/j.ijom.2019.08.005","journal-title":"Int J Oral Maxillofac Surg"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcms.2019.02.011","article-title":"Accuracy of patient-specific implants and additive-manufactured surgical splints in orthognathic surgery - a three-dimensional retrospective study","volume":"47","author":"R\u00fcckschlo\u00df T","year":"2019","unstructured":"R\u00fcckschlo\u00df T, Ristow O, M\u00fcller M, et al.. Accuracy of patient-specific implants and additive-manufactured surgical splints in orthognathic surgery - a three-dimensional retrospective study. J Craniomaxillofac Surg. 2019, 47:847-53. 10.1016\/j.jcms.2019.02.011","journal-title":"J Craniomaxillofac Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/368870-accuracy-assessment-of-customized-titanium-plates-compared-to-3d-printed-splints-in-le-fort-i-osteotomy-a-randomized-clinical-trial-evaluating-clinical-and-radiographic-outcomes","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,15]],"date-time":"2025-05-15T07:32:07Z","timestamp":1747294327000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/368870-accuracy-assessment-of-customized-titanium-plates-compared-to-3d-printed-splints-in-le-fort-i-osteotomy-a-randomized-clinical-trial-evaluating-clinical-and-radiographic-outcomes"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,15]]},"references-count":28,"URL":"https:\/\/doi.org\/10.7759\/cureus.84151","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,15]]}}}