{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:43:20Z","timestamp":1792809800620,"version":"4.5.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,25]]},"DOI":"10.7759\/cureus.84770","type":"journal-article","created":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T12:57:09Z","timestamp":1748177829000},"source":"Crossref","is-referenced-by-count":3,"title":["Tofacitinib in the Treatment of Refractory Adult-Onset Still\u2019s Disease Co-diagnosed With Celiac Disease: A Case Report"],"prefix":"10.7759","author":[{"given":"Mustafa","family":"Alhayali","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/ard.30.2.121","article-title":"Still's disease in the adult","volume":"30","author":"Bywaters EG","year":"1971","unstructured":"Bywaters EG. Still's disease in the adult. Ann Rheum Dis. 1971, 30:121-33. 10.1136\/ard.30.2.121","journal-title":"Ann Rheum Dis"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1007\/s10067-010-1516-1","article-title":"Clinical features and prognosis in adult-onset Still's disease: a study of 104 cases","volume":"29","author":"Kong XD","year":"2010","unstructured":"Kong XD, Xu D, Zhang W, Zhao Y, Zeng X, Zhang F. Clinical features and prognosis in adult-onset Still's disease: a study of 104 cases. Clin Rheumatol. 2010, 29:1015-9. 10.1007\/s10067-010-1516-1","journal-title":"Clin Rheumatol"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2014.01.058","article-title":"Adult-onset Still's disease","volume":"13","author":"Gerfaud-Valentin M","year":"2014","unstructured":"Gerfaud-Valentin M, Jamilloux Y, Iwaz J, S\u00e8ve P. Adult-onset Still's disease. Autoimmun Rev. 2014, 13:708-22. 10.1016\/j.autrev.2014.01.058","journal-title":"Autoimmun Rev"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2019.04.004","article-title":"Racial\/ethnic variations in morbidity and mortality in adult onset Still\u2019s disease: an analysis of national dataset","volume":"49","author":"Mehta BY","year":"2019","unstructured":"Mehta BY, Ibrahim S, Briggs W, Efthimiou P. Racial\/ethnic variations in morbidity and mortality in adult onset Still\u2019s disease: an analysis of national dataset. Semin Arthritis Rheum. 2019, 49:469-73. 10.1016\/j.semarthrit.2019.04.004","journal-title":"Semin Arthritis Rheum"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-1241.2007.01393.x","article-title":"Adult-onset Still's disease","volume":"63","author":"Cagatay Y","year":"2009","unstructured":"Cagatay Y, Gul A, Cagatay A, et al.. Adult-onset Still's disease. Int J Clin Pract. 2009, 63:1050-5. 10.1111\/j.1742-1241.2007.01393.x","journal-title":"Int J Clin Pract"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/acr.23853","article-title":"Long-term outcomes in juvenile idiopathic arthritis: eighteen years of follow-up in the population-based Nordic juvenile idiopathic arthritis cohort","volume":"72","author":"Glerup M","year":"2020","unstructured":"Glerup M, Rypdal V, Arnstad ED, et al.. Long-term outcomes in juvenile idiopathic arthritis: eighteen years of follow-up in the population-based Nordic juvenile idiopathic arthritis cohort. Arthritis Care Res (Hoboken). 2020, 72:507-16. 10.1002\/acr.23853","journal-title":"Arthritis Care Res (Hoboken)"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/ard-2024-225851","article-title":"EULAR\/PReS recommendations for the diagnosis and management of Still's disease, comprising systemic juvenile idiopathic arthritis and adult-onset Still's disease","volume":"83","author":"Fautrel B","year":"2024","unstructured":"Fautrel B, Mitrovic S, De Matteis A, et al.. EULAR\/PReS recommendations for the diagnosis and management of Still's disease, comprising systemic juvenile idiopathic arthritis and adult-onset Still's disease. Ann Rheum Dis. 2024, 83:1614-27. 10.1136\/ard-2024-225851","journal-title":"Ann Rheum Dis"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3390\/jcm10122633","article-title":"Clinical phenotypes of adult-onset Still\u2019s disease: new insights from pathophysiology and literature findings","volume":"10","author":"Mitrovic S","year":"2021","unstructured":"Mitrovic S, Fautrel B. Clinical phenotypes of adult-onset Still\u2019s disease: new insights from pathophysiology and literature findings. J Clin Med. 2021, 10:2633. 10.3390\/jcm10122633","journal-title":"J Clin Med"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-018-1685-x","article-title":"Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils","volume":"20","author":"Furuya MY","year":"2018","unstructured":"Furuya MY, Asano T, Sumichika Y, et al.. Tofacitinib inhibits granulocyte-macrophage colony-stimulating factor-induced NLRP3 inflammasome activation in human neutrophils. Arthritis Res Ther. 2018, 20:196. 10.1186\/s13075-018-1685-x","journal-title":"Arthritis Res Ther"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izy364","article-title":"A JAK1 selective kinase inhibitor and tofacitinib affect macrophage activation and function","volume":"25","author":"De Vries LC","year":"2019","unstructured":"De Vries LC, Duarte JM, De Krijger M, et al.. A JAK1 selective kinase inhibitor and tofacitinib affect macrophage activation and function. Inflamm Bowel Dis. 2019, 25:647-60. 10.1093\/ibd\/izy364","journal-title":"Inflamm Bowel Dis"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1186\/s13075-018-1800-z","article-title":"Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still's disease","volume":"21","author":"Hu Q","year":"2019","unstructured":"Hu Q, Shi H, Zeng T, et al.. Increased neutrophil extracellular traps activate NLRP3 and inflammatory macrophages in adult-onset Still's disease. Arthritis Res Ther. 2019, 21:9. 10.1186\/s13075-018-1800-z","journal-title":"Arthritis Res Ther"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1136\/annrheumdis-2019-216699","article-title":"Tofacitinib in refractory adult-onset Still's disease: 14 cases from a single centre in China","volume":"79","author":"Hu Q","year":"2020","unstructured":"Hu Q, Wang M, Jia J, et al.. Tofacitinib in refractory adult-onset Still's disease: 14 cases from a single centre in China. Ann Rheum Dis. 2020, 79:842-4. 10.1136\/annrheumdis-2019-216699","journal-title":"Ann Rheum Dis"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keac440","article-title":"JAK inhibitors in difficult-to-treat adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis","volume":"62","author":"Gillard L","year":"2023","unstructured":"Gillard L, Pouchot J, Cohen-Aubart F, et al.. JAK inhibitors in difficult-to-treat adult-onset Still's disease and systemic-onset juvenile idiopathic arthritis. Rheumatology (Oxford). 2023, 62:1594-604. 10.1093\/rheumatology\/keac440","journal-title":"Rheumatology (Oxford)"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1093\/rap\/rkae117.038","article-title":"The use of JAK inhibitors in difficult-to-treat adult-onset Still\u2019s disease","volume":"8","author":"Elfar E","year":"2024","unstructured":"Elfar E, Mahto A. The use of JAK inhibitors in difficult-to-treat adult-onset Still\u2019s disease. Rheumatol Adv Pract. 2024, 8:rkae117.038. 10.1093\/rap\/rkae117.038","journal-title":"Rheumatol Adv Pract"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/03009742.2020.1729405","article-title":"Tofacitinib-induced remission in refractory adult-onset Still's disease complicated by macrophage activation syndrome","volume":"49","author":"Honda M","year":"2020","unstructured":"Honda M, Moriyama M, Kondo M, Kumakura S, Murakawa Y. Tofacitinib-induced remission in refractory adult-onset Still's disease complicated by macrophage activation syndrome. Scand J Rheumatol. 2020, 49:336-8. 10.1080\/03009742.2020.1729405","journal-title":"Scand J Rheumatol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1007\/s00393-020-00853-9","article-title":"Successful treatment of adult Still's disease with tofacitinib in a\u00a0HIV-2 positive female patient. (Article in German)","volume":"79","author":"Hoff P","year":"2020","unstructured":"Hoff P, Walther M, Wesselmann H, Weinerth J, Feist E, Ohrndorf S. Successful treatment of adult Still's disease with tofacitinib in a\u00a0HIV-2 positive female patient. (Article in German). Z Rheumatol. 2020, 79:1046-9. 10.1007\/s00393-020-00853-9","journal-title":"Z Rheumatol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/key414","article-title":"Treatment of refractory adult onset Still's disease with combination anakinra and baricitinib therapy","volume":"58","author":"Ladhari C","year":"2019","unstructured":"Ladhari C, Jorgensen C, Pers YM. Treatment of refractory adult onset Still's disease with combination anakinra and baricitinib therapy. Rheumatology (Oxford). 2019, 58:736-7. 10.1093\/rheumatology\/key414","journal-title":"Rheumatology (Oxford)"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s40268-023-00417-7","article-title":"Efficacy of baricitinib in patients with refractory adult-onset Still\u2019s disease","volume":"23","author":"Sun Z","year":"2023","unstructured":"Sun Z, Li R, Wang Y, Han F, Wei W, Li X. Efficacy of baricitinib in patients with refractory adult-onset Still\u2019s disease. Drugs R D. 2023, 23:109-20. 10.1007\/s40268-023-00417-7","journal-title":"Drugs R D"},{"key":"ref19","doi-asserted-by":"crossref","DOI":"10.4103\/0019-5359.33191","article-title":"Celiac disease: association with adult-onset Still's disease: apropos of a clinical case","volume":"61","author":"Kumar S","year":"2007","unstructured":"Kumar S, Gupta N, Jhamb R, Mishra D. Celiac disease: association with adult-onset Still's disease: apropos of a clinical case. Indian J Med Sci. 2007, 61:414-7.","journal-title":"Indian J Med Sci"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/s0165-2478(02)00243-2","article-title":"Relationship between IL-18 and sICAM-1 serum levels in patients affected by coeliac disease: preliminary considerations","volume":"85","author":"Merendino RA","year":"2003","unstructured":"Merendino RA, Di Pasquale G, Sturniolo GC, et al.. Relationship between IL-18 and sICAM-1 serum levels in patients affected by coeliac disease: preliminary considerations. Immunol Lett. 2003, 85:257-60. 10.1016\/s0165-2478(02)00243-2","journal-title":"Immunol Lett"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/371748-tofacitinib-in-the-treatment-of-refractory-adult-onset-stills-disease-co-diagnosed-with-celiac-disease-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T12:57:10Z","timestamp":1748177830000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/371748-tofacitinib-in-the-treatment-of-refractory-adult-onset-stills-disease-co-diagnosed-with-celiac-disease-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,25]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.84770","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,25]]}}}