{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T20:10:06Z","timestamp":1748203806914,"version":"3.41.0"},"reference-count":27,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,25]]},"DOI":"10.7759\/cureus.84792","type":"journal-article","created":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T19:41:08Z","timestamp":1748202068000},"source":"Crossref","is-referenced-by-count":0,"title":["Survival Disparities in Adenocarcinoma Within Adenomatous Polyps: A National Cancer Database Analysis"],"prefix":"10.7759","author":[{"given":"Catherine S","family":"Taghizadeh","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Beau","family":"Hsia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanick","family":"Tade","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susan","family":"Rafie","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Akaash","family":"Surendra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter T","family":"Silberstein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Deepak","family":"Vadehra","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy J","family":"Brown","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"Colorectal polyps. (2023). Accessed. November 25, 2024: https:\/\/www.mountsinai.org\/health-library\/diseases-conditions\/colorectal-polyps#:~:text=Adenomatous%20polyps%20are%20...."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-023-04460-5","article-title":"Metastasis organotropism in colorectal cancer: advancing toward innovative therapies","volume":"21","author":"He K","year":"2023","unstructured":"He K, Wang Z, Luo M, et al.. Metastasis organotropism in colorectal cancer: advancing toward innovative therapies. J Transl Med. 2023, 21:612. 10.1186\/s12967-023-04460-5","journal-title":"J Transl Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3322\/caac.21763","article-title":"Cancer statistics, 2023","volume":"73","author":"Siegel RL","year":"2023","unstructured":"Siegel RL, Miller KD, Wagle NS, Jemal A. Cancer statistics, 2023. CA Cancer J Clin. 2023, 73:17-48. 10.3322\/caac.21763","journal-title":"CA Cancer J Clin"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2021.4847","article-title":"Emerging trends in colorectal cancer: dysregulated signaling pathways (review)","volume":"47","author":"Ahmad R","year":"2021","unstructured":"Ahmad R, Singh JK, Wunnava A, Al-Obeed O, Abdulla M, Srivastava SK. Emerging trends in colorectal cancer: dysregulated signaling pathways (review). Int J Mol Med. 2021, 47:14. 10.3892\/ijmm.2021.4847","journal-title":"Int J Mol Med"},{"key":"ref5","unstructured":"Cancerous polyps. overview, definition &amp; treatment. (2022). Accessed: November 25, 2024: https:\/\/my.clevelandclinic.org\/health\/symptoms\/22453-cancerous-polyps."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-916274","article-title":"Colorectal cancer: epidemiology, risk factors, and health services","volume":"18","author":"Amersi F","year":"2005","unstructured":"Amersi F, Agustin M, Ko CY. Colorectal cancer: epidemiology, risk factors, and health services. Clin Colon Rectal Surg. 2005, 18:133-40. 10.1055\/s-2005-916274","journal-title":"Clin Colon Rectal Surg"},{"key":"ref7","unstructured":"Colorectal cancer signs and symptoms. (2024). Accessed. April 22, 2025: https:\/\/www.cancer.org\/cancer\/types\/colon-rectal-cancer\/detection-diagnosis-staging\/signs-and-symptoms.html."},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-21525-4","article-title":"Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations","volume":"8","author":"Druliner BR","year":"2018","unstructured":"Druliner BR, Wang P, Bae T, et al.. Molecular characterization of colorectal adenomas with and without malignancy reveals distinguishing genome, transcriptome and methylome alterations. Sci Rep. 2018, 8:3161. 10.1038\/s41598-018-21525-4","journal-title":"Sci Rep"},{"key":"ref9","unstructured":"Colon cancer treatment. (2025). Accessed. April 22, 2025: https:\/\/www.cancer.gov\/types\/colorectal\/patient\/colon-treatment-pdq."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.06.178","article-title":"Use of adjuvant chemotherapy and radiation therapy for colorectal cancer in a population-based cohort","volume":"21","author":"Ayanian JZ","year":"2003","unstructured":"Ayanian JZ, Zaslavsky AM, Fuchs CS, et al.. Use of adjuvant chemotherapy and radiation therapy for colorectal cancer in a population-based cohort. J Clin Oncol. 2003, 21:1293-300. 10.1200\/JCO.2003.06.178","journal-title":"J Clin Oncol"},{"key":"ref11","unstructured":"Colorectal cancer survival rates. colorectal cancer prognosis. (2025). Accessed: March 1, 2025: https:\/\/www.cancer.org\/cancer\/types\/colon-rectal-cancer\/detection-diagnosis-staging\/survival-rates.html."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-71999-8","article-title":"Sex differences in survival outcomes of early-onset colorectal cancer","volume":"14","author":"Afify AY","year":"2024","unstructured":"Afify AY, Ashry MH, Hassan H. Sex differences in survival outcomes of early-onset colorectal cancer. Sci Rep. 2024, 14:22041. 10.1038\/s41598-024-71999-8","journal-title":"Sci Rep"},{"key":"ref13","unstructured":"Participant user files. (2025). Accessed. November 25, 2024: https:\/\/www.facs.org\/quality-programs\/cancer-programs\/national-cancer-database\/puf\/?utm_medium=email&amp;utm_source=trans...."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3390\/medsci6020031","article-title":"Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells","volume":"6","author":"Testa U","year":"2018","unstructured":"Testa U, Pelosi E, Castelli G. Colorectal cancer: genetic abnormalities, tumor progression, tumor heterogeneity, clonal evolution and tumor-initiating cells. Med Sci (Basel). 2018, 6:31. 10.3390\/medsci6020031","journal-title":"Med Sci (Basel)"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.14309\/ajg.0000000000002171","article-title":"Molecular characteristics of early-onset colorectal cancer according to detailed anatomical locations: comparison with later-onset cases","volume":"118","author":"Ugai T","year":"2023","unstructured":"Ugai T, Haruki K, Harrison TA, et al.. Molecular characteristics of early-onset colorectal cancer according to detailed anatomical locations: comparison with later-onset cases. Am J Gastroenterol. 2023, 118:712-26. 10.14309\/ajg.0000000000002171","journal-title":"Am J Gastroenterol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.4174\/astr.2017.93.5.266","article-title":"Histopathologic risk factors for lymph node metastasis in patients with T1 colorectal cancer","volume":"93","author":"Ha RK","year":"2017","unstructured":"Ha RK, Han KS, Sohn DK, et al.. Histopathologic risk factors for lymph node metastasis in patients with T1 colorectal cancer. Ann Surg Treat Res. 2017, 93:266-71. 10.4174\/astr.2017.93.5.266","journal-title":"Ann Surg Treat Res"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0000000000003854","article-title":"Lymphovascular infiltration, not depth of invasion, is the critical risk factor of metastases in early colorectal cancer: retrospective population-based cohort study on prospectively collected data, including validation","volume":"275","author":"R\u00f6nnow CF","year":"2022","unstructured":"R\u00f6nnow CF, Arthursson V, Toth E, Krarup PM, Syk I, Thorlacius H. Lymphovascular infiltration, not depth of invasion, is the critical risk factor of metastases in early colorectal cancer: retrospective population-based cohort study on prospectively collected data, including validation. Ann Surg. 2022, 275:e148-54. 10.1097\/SLA.0000000000003854","journal-title":"Ann Surg"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v29.i13.1911","article-title":"Application of nanotechnology in reversing therapeutic resistance and controlling metastasis of colorectal cancer","volume":"29","author":"Ren SN","year":"2023","unstructured":"Ren SN, Zhang ZY, Guo RJ, Wang DR, Chen FF, Chen XB, Fang XD. Application of nanotechnology in reversing therapeutic resistance and controlling metastasis of colorectal cancer. World J Gastroenterol. 2023, 29:1911-41. 10.3748\/wjg.v29.i13.1911","journal-title":"World J Gastroenterol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1200\/JGO.19.00367","article-title":"Treatment of patients with late-stage colorectal cancer: ASCO resource-stratified guideline","volume":"6","author":"Chiorean EG","year":"2020","unstructured":"Chiorean EG, Nandakumar G, Fadelu T, et al.. Treatment of patients with late-stage colorectal cancer: ASCO resource-stratified guideline. JCO Glob Oncol. 2020, 6:414-38. 10.1200\/JGO.19.00367","journal-title":"JCO Glob Oncol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-87929-x","article-title":"Clinicopathological factors associated with synchronous distant metastasis and prognosis of stage T1 colorectal cancer patients","volume":"11","author":"Li Q","year":"2021","unstructured":"Li Q, Wang G, Luo J, Li B, Chen W. Clinicopathological factors associated with synchronous distant metastasis and prognosis of stage T1 colorectal cancer patients. Sci Rep. 2021, 11:8722. 10.1038\/s41598-021-87929-x","journal-title":"Sci Rep"},{"key":"ref21","unstructured":"Colorectal cancer facts and statistics. (2025). Accessed. April 22, 2025: https:\/\/colorectalcancer.org\/basics\/facts-and-statistics."},{"key":"ref22","unstructured":"Epidemiology and risk factors for colorectal cancer. (2025). Accessed. April 22, 2025: https:\/\/www.uptodate.com\/contents\/epidemiology-and-risk-factors-for-colorectal-cancer."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.26677","article-title":"Socioeconomic status and the risk of colorectal cancer: an analysis of more than a half million adults in the National Institutes of Health-AARP Diet and Health Study","volume":"118","author":"Doubeni CA","year":"2012","unstructured":"Doubeni CA, Laiyemo AO, Major JM, et al.. Socioeconomic status and the risk of colorectal cancer: an analysis of more than a half million adults in the National Institutes of Health-AARP Diet and Health Study. Cancer. 2012, 118:3636-44. 10.1002\/cncr.26677","journal-title":"Cancer"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.3390\/ijerph182212164","article-title":"Impact of socioeconomic status on cancer incidence risk, cancer staging, and survival of patients with colorectal cancer under universal health insurance coverage in Taiwan","volume":"18","author":"Kuo WY","year":"2021","unstructured":"Kuo WY, Hsu HS, Kung PT, Tsai WC. Impact of socioeconomic status on cancer incidence risk, cancer staging, and survival of patients with colorectal cancer under universal health insurance coverage in Taiwan. Int J Environ Res Public Health. 2021, 18:12164. 10.3390\/ijerph182212164","journal-title":"Int J Environ Res Public Health"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2024.05.031","article-title":"Low neighborhood socioeconomic status is associated with poor outcomes in young adults with colorectal cancer","volume":"176","author":"Ko TM","year":"2024","unstructured":"Ko TM, Laraia KN, Alexander HR, et al.. Low neighborhood socioeconomic status is associated with poor outcomes in young adults with colorectal cancer. Surgery. 2024, 176:626-32. 10.1016\/j.surg.2024.05.031","journal-title":"Surgery"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.2105\/ajph.90.11.1746","article-title":"Effects of health insurance and race on colorectal cancer treatments and outcomes","volume":"90","author":"Roetzheim RG","year":"2000","unstructured":"Roetzheim RG, Pal N, Gonzalez EC, Ferrante JM, Van Durme DJ, Krischer JP. Effects of health insurance and race on colorectal cancer treatments and outcomes. Am J Public Health. 2000, 90:1746-54. 10.2105\/ajph.90.11.1746","journal-title":"Am J Public Health"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.5114\/pg.2018.81072","article-title":"Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors","volume":"14","author":"Rawla P","year":"2019","unstructured":"Rawla P, Sunkara T, Barsouk A. Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors. Prz Gastroenterol. 2019, 14:89-103. 10.5114\/pg.2018.81072","journal-title":"Prz Gastroenterol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/362910-survival-disparities-in-adenocarcinoma-within-adenomatous-polyps-a-national-cancer-database-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,25]],"date-time":"2025-05-25T19:41:11Z","timestamp":1748202071000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/362910-survival-disparities-in-adenocarcinoma-within-adenomatous-polyps-a-national-cancer-database-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,25]]},"references-count":27,"URL":"https:\/\/doi.org\/10.7759\/cureus.84792","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,25]]}}}