{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T05:30:40Z","timestamp":1771997440858,"version":"3.50.1"},"reference-count":23,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,26]]},"DOI":"10.7759\/cureus.84848","type":"journal-article","created":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T17:30:27Z","timestamp":1748280627000},"source":"Crossref","is-referenced-by-count":1,"title":["Comparison of 1-cm Versus 2-cm Excision Margins for Cutaneous Melanoma: A Systematic Review and Meta-Analysis"],"prefix":"10.7759","author":[{"given":"Darya","family":"Pospyelova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Bunola-Hadfield","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martha F","family":"De La Cruz Monroy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahmoud A","family":"Kandil","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lauren-Jane","family":"Fredericks-Bowyer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Haris","family":"Duvnjak","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Himani","family":"Murdeshwar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shafiq","family":"Rahman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","unstructured":"Melanoma. (2025). Accessed. 20 January 2025: https:\/\/www.bad.org.uk\/referrals\/melanoma\/."},{"key":"ref2","unstructured":"Melanoma. (2022). Accessed. 31 October 2024: https:\/\/cks.nice.org.uk\/topics\/melanoma."},{"key":"ref3","unstructured":"Melanoma. assessment and management. (2015). Accessed: 20 January 2025: https:\/\/www.nice.org.uk\/guidance\/ng14."},{"key":"ref4","unstructured":"Melanoma. cutaneous. (2024). Accessed: 31 October 2024: https:\/\/www.nccn.org\/home.."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2015.03.029","article-title":"A retrospective study of 1- versus 2-cm excision margins for cutaneous malignant melanomas thicker than 2 mm","volume":"72","author":"Hunger RE","year":"2015","unstructured":"Hunger RE, Angermeier S, Seyed Jafari SM, Ochsenbein A, Shafighi M. A retrospective study of 1- versus 2-cm excision margins for cutaneous malignant melanomas thicker than 2 mm. J Am Acad Dermatol. 2015, 72:1054-9. 10.1016\/j.jaad.2015.03.029","journal-title":"J Am Acad Dermatol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-323-05711-0.X0001-8","article-title":"Melanoma","author":"Martin D","year":"2018","unstructured":"Martin D, McCarter MD. Melanoma. Abernathy\u2019s Surgical Secrets. Elsevier, Philadelphia; 2018. 10.1016\/B978-0-323-05711-0.X0001-8"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa030681","article-title":"Excision margins in high-risk malignant melanoma","volume":"350","author":"Thomas JM","year":"2004","unstructured":"Thomas JM, Newton-Bishop J, A'Hern R, et al.. Excision margins in high-risk malignant melanoma. N Engl J Med. 2004, 350:757-66. 10.1056\/NEJMoa030681","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-012-2543-8","article-title":"1 or 2 cm margins of excision for T2 melanomas: do they impact recurrence or survival?","volume":"20","author":"Hudson LE","year":"2013","unstructured":"Hudson LE, Maithel SK, Carlson GW, Rizzo M, Murray DR, Hestley AC, Delman KA. 1 or 2 cm margins of excision for T2 melanomas: do they impact recurrence or survival?. Ann Surg Oncol. 2013, 20:346-51. 10.1245\/s10434-012-2543-8","journal-title":"Ann Surg Oncol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1097\/DSS.0000000000000465","article-title":"One-cm versus 2-cm excision margins for patients with intermediate thickness melanoma: a matched-pair analysis","volume":"41","author":"Koskivuo I","year":"2015","unstructured":"Koskivuo I, Giordano S, Ver\u00e4j\u00e4nkorva E, Vihinen P. One-cm versus 2-cm excision margins for patients with intermediate thickness melanoma: a matched-pair analysis. Dermatol Surg. 2015, 41:1130-6. 10.1097\/DSS.0000000000000465","journal-title":"Dermatol Surg"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)31132-8","article-title":"2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial","volume":"394","author":"Utj\u00e9s D","year":"2019","unstructured":"Utj\u00e9s D, Malmstedt J, Teras J, et al.. 2-cm versus 4-cm surgical excision margins for primary cutaneous melanoma thicker than 2 mm: long-term follow-up of a multicentre, randomised trial. Lancet. 2019, 394:8. 10.1016\/S0140-6736(19)31132-8","journal-title":"Lancet"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-016-5167-6","article-title":"Is a wider margin (2 cm vs. 1 cm) for a 1.01-2.0 mm melanoma necessary?","volume":"23","author":"Doepker MP","year":"2016","unstructured":"Doepker MP, Thompson ZJ, Fisher KJ, et al.. Is a wider margin (2 cm vs. 1 cm) for a 1.01-2.0 mm melanoma necessary?. Ann Surg Oncol. 2016, 23:2336-42. 10.1245\/s10434-016-5167-6","journal-title":"Ann Surg Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(15)00482-9","article-title":"Wide versus narrow excision margins for high-risk, primary cutaneous melanomas: long-term follow-up of survival in a randomised trial","volume":"17","author":"Hayes AJ","year":"2016","unstructured":"Hayes AJ, Maynard L, Coombes G, et al.. Wide versus narrow excision margins for high-risk, primary cutaneous melanomas: long-term follow-up of survival in a randomised trial. Lancet Oncol. 2016, 17:184-92. 10.1016\/S1470-2045(15)00482-9","journal-title":"Lancet Oncol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2015.10.013","article-title":"Surgical excision margins in primary cutaneous melanoma: a meta-analysis and Bayesian probability evaluation","volume":"42","author":"Wheatley K","year":"2016","unstructured":"Wheatley K, Wilson JS, Gaunt P, Marsden JR. Surgical excision margins in primary cutaneous melanoma: a meta-analysis and Bayesian probability evaluation. Cancer Treat Rev. 2016, 42:73-81. 10.1016\/j.ctrv.2015.10.013","journal-title":"Cancer Treat Rev"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.137.10.1101","article-title":"Excision margins in the treatment of primary cutaneous melanoma: a systematic review of randomized controlled trials comparing narrow vs wide excision","volume":"137","author":"Lens MB","year":"2002","unstructured":"Lens MB, Dawes M, Goodacre T, Bishop JA. Excision margins in the treatment of primary cutaneous melanoma: a systematic review of randomized controlled trials comparing narrow vs wide excision. Arch Surg. 2002, 137:1101-5. 10.1001\/archsurg.137.10.1101","journal-title":"Arch Surg"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000097","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"6","author":"Moher D","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. PLoS Med. 2009, 6:e1000097. 10.1371\/journal.pmed.1000097","journal-title":"PLoS Med"},{"key":"ref16","unstructured":"The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. (2024). Accessed. 31 October 2024: https:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp."},{"key":"ref17","article-title":"Chapter 8: Assessing risk of bias in a randomized trial","author":"Higgins JP","year":"2023","unstructured":"Higgins JP, Savovi\u0107 J, Page MJ, Elbers RG, Sterne JA. Chapter 8: Assessing risk of bias in a randomized trial. Cochrane Handbook for Systematic Reviews of Interventions version 6.5. Higgins JP, Thomas J, Chandler J, Cumpston M, Li T, Page MJ, Welch VA (ed): Cochrane, London; 2023."},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-015-4575-3","article-title":"Minimum safe pathologic excision margins for primary cutaneous melanomas (1-2 mm in thickness): analysis of 2131 patients treated at a single center","volume":"23","author":"Haydu LE","year":"2016","unstructured":"Haydu LE, Stollman JT, Scolyer RA, et al.. Minimum safe pathologic excision margins for primary cutaneous melanomas (1-2 mm in thickness): analysis of 2131 patients treated at a single center. Ann Surg Oncol. 2016, 23:1071-81. 10.1245\/s10434-015-4575-3","journal-title":"Ann Surg Oncol"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23886","article-title":"Reducing margins of wide local excision in head and neck melanoma for function and cosmesis: 5-year local recurrence-free survival","volume":"111","author":"Rawlani R","year":"2015","unstructured":"Rawlani R, Rawlani V, Qureshi HA, Kim JY, Wayne JD. Reducing margins of wide local excision in head and neck melanoma for function and cosmesis: 5-year local recurrence-free survival. J Surg Oncol. 2015, 111:795-9. 10.1002\/jso.23886","journal-title":"J Surg Oncol"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-018-6470-1","article-title":"1 versus 2-cm excision margins for PT2-PT4 primary cutaneous melanoma (MelMarT): a feasibility study","volume":"25","author":"Moncrieff MD","year":"2018","unstructured":"Moncrieff MD, Gyorki D, Saw R, et al.. 1 versus 2-cm excision margins for PT2-PT4 primary cutaneous melanoma (MelMarT): a feasibility study. Ann Surg Oncol. 2018, 25:2541-9. 10.1245\/s10434-018-6470-1","journal-title":"Ann Surg Oncol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1097\/PRS.0000000000002367","article-title":"Malignant melanoma: beyond the basics","volume":"138","author":"Pavri SN","year":"2016","unstructured":"Pavri SN, Clune J, Ariyan S, Narayan D. Malignant melanoma: beyond the basics. Plast Reconstr Surg. 2016, 138:330e-40e. 10.1097\/PRS.0000000000002367","journal-title":"Plast Reconstr Surg"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1177\/229255031202000108","article-title":"Cosmetic outcomes following head and neck melanoma reconstruction: the patient's perspective","volume":"20","author":"Buck D 2nd","year":"2012","unstructured":"Buck D 2nd, Rawlani V, Wayne J, et al.. Cosmetic outcomes following head and neck melanoma reconstruction: the patient's perspective. Can J Plast Surg. 2012, 20:e10-5. 10.1177\/229255031202000108","journal-title":"Can J Plast Surg"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.cpsurg.2024.101440","article-title":"Challenges in rural plastic surgery: availability, scope of practice, and motivating factors","volume":"61","author":"Koenig ZA","year":"2024","unstructured":"Koenig ZA, Henderson JT, Meaike JD, Gelman JJ. Challenges in rural plastic surgery: availability, scope of practice, and motivating factors. Curr Probl Surg. 2024, 61:101440. 10.1016\/j.cpsurg.2024.101440","journal-title":"Curr Probl Surg"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/363140-comparison-of-1-cm-versus-2-cm-excision-margins-for-cutaneous-melanoma-a-systematic-review-and-meta-analysis","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,26]],"date-time":"2025-05-26T17:30:29Z","timestamp":1748280629000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/363140-comparison-of-1-cm-versus-2-cm-excision-margins-for-cutaneous-melanoma-a-systematic-review-and-meta-analysis"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,26]]},"references-count":23,"URL":"https:\/\/doi.org\/10.7759\/cureus.84848","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,26]]}}}