{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,18]],"date-time":"2026-07-18T21:09:06Z","timestamp":1784408946828,"version":"3.55.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,26]]},"DOI":"10.7759\/cureus.84863","type":"journal-article","created":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T04:56:11Z","timestamp":1748321771000},"source":"Crossref","is-referenced-by-count":1,"title":["A Case of Graves\u2019 Disease Exacerbation Triggered by BNT162b2 Vaccination"],"prefix":"10.7759","author":[{"given":"Hideyuki","family":"Iwamoto","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tomohiko","family":"Kimura","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erina","family":"Nakao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fuminori","family":"Tatsumi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideaki","family":"Kaneto","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1007\/s12020-017-1306-5","article-title":"Epidemiology, management and outcomes of Graves' disease-real life data","volume":"56","author":"Hussain YS","year":"2017","unstructured":"Hussain YS, Hookham JC, Allahabadia A, Balasubramanian SP. Epidemiology, management and outcomes of Graves' disease-real life data. Endocrine. 2017, 56:568-578. 10.1007\/s12020-017-1306-5","journal-title":"Endocrine"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3389\/fpubh.2023.1259084","article-title":"Temporary impact on medical system and effectiveness of mitigation strategies after COVID-19 policy adjustment in China: a modeling study","volume":"11","author":"Hon C","year":"2023","unstructured":"Hon C, Liang J, Chen R, et al.. Temporary impact on medical system and effectiveness of mitigation strategies after COVID-19 policy adjustment in China: a modeling study. Front Public Health. 2023, 11:1259084. 10.3389\/fpubh.2023.1259084","journal-title":"Front Public Health"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3389\/fpsyt.2023.1179803","article-title":"Behind the scenes of the healthcare COVID-19 pandemic crisis: potential affecting factors of healthcare work sustainability in Romania during 2020-2022","volume":"14","author":"Savu C","year":"2023","unstructured":"Savu C, Arma\u0219 I, Burcea M, Dobre D. Behind the scenes of the healthcare COVID-19 pandemic crisis: potential affecting factors of healthcare work sustainability in Romania during 2020-2022. Front Psychiatry. 2023, 14:1179803. 10.3389\/fpsyt.2023.1179803","journal-title":"Front Psychiatry"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-021-00578-z","article-title":"Immunological mechanisms of vaccine-induced protection against COVID-19 in humans","volume":"21","author":"Sadarangani M","year":"2021","unstructured":"Sadarangani M, Marchant A, Kollmann TR. Immunological mechanisms of vaccine-induced protection against COVID-19 in humans. Nat Rev Immunol. 2021, 21:475-484. 10.1038\/s41577-021-00578-z","journal-title":"Nat Rev Immunol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2034577","article-title":"Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine","volume":"383","author":"Polack FP","year":"2020","unstructured":"Polack FP, Thomas SJ, Kitchin N, et al.. Safety and efficacy of the BNT162b2 mRNA COVID-19 vaccine. N Engl J Med. 2020, 383:2603-2615. 10.1056\/NEJMoa2034577","journal-title":"N Engl J Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2021.15072","article-title":"Surveillance for adverse events after COVID-19 mRNA vaccination","volume":"326","author":"Klein NP","year":"2021","unstructured":"Klein NP, Lewis N, Goddard K, et al.. Surveillance for adverse events after COVID-19 mRNA vaccination. JAMA. 2021, 326:1390-1399. 10.1001\/jama.2021.15072","journal-title":"JAMA"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s12902-023-01387-2","article-title":"Graves' disease after exposure to the SARS-CoV-2 vaccine: a case report and review of the literature","volume":"23","author":"Takedani K","year":"2023","unstructured":"Takedani K, Notsu M, Ishiai N, Asami Y, Uchida K, Kanasaki K. Graves' disease after exposure to the SARS-CoV-2 vaccine: a case report and review of the literature. BMC Endocr Disord. 2023, 23:132. 10.1186\/s12902-023-01387-2","journal-title":"BMC Endocr Disord"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2021.102738","article-title":"A case of Graves' disease and type 1 diabetes mellitus following SARS-CoV-2 vaccination","volume":"125","author":"Patrizio A","year":"2021","unstructured":"Patrizio A, Ferrari SM, Antonelli A, Fallahi P. A case of Graves' disease and type 1 diabetes mellitus following SARS-CoV-2 vaccination. J Autoimmun. 2021, 125:102738. 10.1016\/j.jaut.2021.102738","journal-title":"J Autoimmun"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1210\/clinem\/dgac119","article-title":"SARS-CoV-2 mRNA vaccination and Graves' disease: a report of 12 cases and review of the literature","volume":"107","author":"Chee YJ","year":"2022","unstructured":"Chee YJ, Liew H, Hoi WH, et al.. SARS-CoV-2 mRNA vaccination and Graves' disease: a report of 12 cases and review of the literature. J Clin Endocrinol Metab. 2022, 107:e2324-e2330. 10.1210\/clinem\/dgac119","journal-title":"J Clin Endocrinol Metab"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.04.055","article-title":"Vaccine adjuvants: understanding the structure and mechanism of adjuvanticity","volume":"37","author":"Shi S","year":"2019","unstructured":"Shi S, Zhu H, Xia X, Liang Z, Ma X, Sun B. Vaccine adjuvants: understanding the structure and mechanism of adjuvanticity. Vaccine. 2019, 37:3167-3178. 10.1016\/j.vaccine.2019.04.055","journal-title":"Vaccine"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.1c05922","article-title":"Polyethylene glycol immunogenicity: theoretical, clinical, and practical aspects of anti-polyethylene glycol antibodies","volume":"15","author":"Chen BM","year":"2021","unstructured":"Chen BM, Cheng TL, Roffler SR. Polyethylene glycol immunogenicity: theoretical, clinical, and practical aspects of anti-polyethylene glycol antibodies. ACS Nano. 2021, 15:14022-14048. 10.1021\/acsnano.1c05922","journal-title":"ACS Nano"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.617089","article-title":"Reaction of human monoclonal antibodies to SARS-CoV-2 proteins with tissue antigens: implications for autoimmune diseases","volume":"11","author":"Vojdani A","year":"2020","unstructured":"Vojdani A, Vojdani E, Kharrazian D. Reaction of human monoclonal antibodies to SARS-CoV-2 proteins with tissue antigens: implications for autoimmune diseases. Front Immunol. 2020, 11:617089. 10.3389\/fimmu.2020.617089","journal-title":"Front Immunol"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2022.938001","article-title":"Graves' disease following vaccination against SARS-CoV-2: a systematic review of the reported cases","volume":"13","author":"Triantafyllidis KK","year":"2022","unstructured":"Triantafyllidis KK, Giannos P, Stathi D, Kechagias KS. Graves' disease following vaccination against SARS-CoV-2: a systematic review of the reported cases. Front Endocrinol (Lausanne). 2022, 13:938001. 10.3389\/fendo.2022.938001","journal-title":"Front Endocrinol (Lausanne)"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines9080815","article-title":"Vaccinations and autoimmune diseases","volume":"9","author":"Olivieri B","year":"2021","unstructured":"Olivieri B, Betterle C, Zanoni G. Vaccinations and autoimmune diseases. Vaccines (Basel). 2021, 9:815. 10.3390\/vaccines9080815","journal-title":"Vaccines (Basel)"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3390\/medicina59020364","article-title":"Vaccines and autoimmunity-from side effects to ASIA syndrome","volume":"59","author":"Seida I","year":"2023","unstructured":"Seida I, Seida R, Elsalti A, Mahroum N. Vaccines and autoimmunity-from side effects to ASIA syndrome. Medicina (Kaunas). 2023, 59:364. 10.3390\/medicina59020364","journal-title":"Medicina (Kaunas)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/364550-a-case-of-graves-disease-exacerbation-triggered-by-bnt162b2-vaccination","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,27]],"date-time":"2025-05-27T04:56:11Z","timestamp":1748321771000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/364550-a-case-of-graves-disease-exacerbation-triggered-by-bnt162b2-vaccination"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,26]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.84863","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,26]]}}}