{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,11]],"date-time":"2026-06-11T10:25:14Z","timestamp":1781173514446,"version":"3.54.1"},"reference-count":29,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,5,28]]},"DOI":"10.7759\/cureus.85004","type":"journal-article","created":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T04:00:01Z","timestamp":1748491201000},"source":"Crossref","is-referenced-by-count":2,"title":["Anti-M Antibody in Blood Transfusion: An Underestimated Factor in Service Delays and Expenditures"],"prefix":"10.7759","author":[{"given":"Suman S","family":"Routray","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nirupama","family":"Sahoo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biswajit","family":"Bhuyan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sukanta","family":"Tripathy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gopal K","family":"Ray","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Devi","family":"Acharya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abhra","family":"Barman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","article-title":"Prevalence of Rh, Duffy, Kell, Kidd & MNSs blood group antigens in the Indian blood donor population","volume":"137","author":"Makroo RN","year":"2013","unstructured":"Makroo RN, Bhatia A, Gupta R, Phillip J. Prevalence of Rh, Duffy, Kell, Kidd & MNSs blood group antigens in the Indian blood donor population. Indian J Med Res. 2013, 137:521-6.","journal-title":"Indian J Med Res"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/j.htct.2020.09.150","article-title":"Anti-M antibody and ABO blood grouping discrepancy: a report of three cases with review of literature","volume":"44","author":"Ferdowsi S","year":"2022","unstructured":"Ferdowsi S, Mohammadi S, Ahmadnezhad M, Herfat F, Rezvani A, Eshghi P, Oodi A. Anti-M antibody and ABO blood grouping discrepancy: a report of three cases with review of literature. Hematol Transfus Cell Ther. 2022, 44:288-90. 10.1016\/j.htct.2020.09.150","journal-title":"Hematol Transfus Cell Ther"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1055\/s-0037-1607028","article-title":"Anti-M alloimmunization: management and outcome at a single institution","volume":"7","author":"Stetson B","year":"2017","unstructured":"Stetson B, Scrape S, Markham KB. Anti-M alloimmunization: management and outcome at a single institution. AJP Rep. 2017, 7:e205-10. 10.1055\/s-0037-1607028","journal-title":"AJP Rep"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmae038","article-title":"Acute hemolytic transfusion reaction caused by anti-M antibodies: a case report and literature review","volume":"55","author":"He Y","year":"2024","unstructured":"He Y, Li Y, Wang Q. Acute hemolytic transfusion reaction caused by anti-M antibodies: a case report and literature review. Lab Med. 2024, 55:795-801. 10.1093\/labmed\/lmae038","journal-title":"Lab Med"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.7860\/NJLM\/2024\/70035.2880","article-title":"Impact of anti-M on grouping and cross matching: the challenges faced in three cases","volume":"13","author":"Jonahs B","year":"2024","unstructured":"Jonahs B, Krishnamoorthy R, Ashwin NR, Rathan N, Kumar S. Impact of anti-M on grouping and cross matching: the challenges faced in three cases. Natl Lab Med. 2024, 13:7-10. 10.7860\/NJLM\/2024\/70035.2880","journal-title":"Natl Lab Med"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.4103\/ajts.AJTS_4_17","article-title":"Prevalence of irregular red cell antibody in healthy blood donors attending a tertiary care hospital in North India","volume":"12","author":"Makroo RN","year":"2018","unstructured":"Makroo RN, Rajput S, Agarwal S, Chowdhry M, Prakash B, Karna P. Prevalence of irregular red cell antibody in healthy blood donors attending a tertiary care hospital in North India. Asian J Transfus Sci. 2018, 12:17-20. 10.4103\/ajts.AJTS_4_17","journal-title":"Asian J Transfus Sci"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.5603\/jtm.99707","article-title":"Interference of anti-M antibody with ABO blood grouping--own experience","volume":"17","author":"Sowa B","year":"2024","unstructured":"Sowa B, Kunysz M. Interference of anti-M antibody with ABO blood grouping--own experience. J Transf Med. 2024, 17:1-6. 10.5603\/jtm.99707","journal-title":"J Transf Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/IJPM.IJPM_166_19","article-title":"Management of transfusion needs in a case of immunizing anti-M antibody in a patient with acute myeloid leukemia","volume":"63","author":"Navkudkar A","year":"2020","unstructured":"Navkudkar A, Desai P, Thakkar R, Rajadhyaksha S. Management of transfusion needs in a case of immunizing anti-M antibody in a patient with acute myeloid leukemia. Indian J Pathol Microbiol. 2020, 63:251-4. 10.4103\/IJPM.IJPM_166_19","journal-title":"Indian J Pathol Microbiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.5858\/2003-127-0533-TASCFS","article-title":"Type and screen completion for scheduled surgical procedures. A College of American Pathologists Q-Probes study of 8941 type and screen tests in 108 institutions","volume":"127","author":"Friedberg RC","year":"2003","unstructured":"Friedberg RC, Jones BA, Walsh MK. Type and screen completion for scheduled surgical procedures. A College of American Pathologists Q-Probes study of 8941 type and screen tests in 108 institutions. Arch Pathol Lab Med. 2003, 127:533-40. 10.5858\/2003-127-0533-TASCFS","journal-title":"Arch Pathol Lab Med"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2023.1264853","article-title":"Rare blood group registry in India-current challenges and future perspectives","volume":"14","author":"Datta SS","year":"2023","unstructured":"Datta SS, Sil S, Mandal S. Rare blood group registry in India-current challenges and future perspectives. Front Genet. 2023, 14:1264853. 10.3389\/fgene.2023.1264853","journal-title":"Front Genet"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4103\/ajts.AJTS_54_18","article-title":"Patient blood management in a patient with multiple red cell antibodies (anti-C, anti-e, and anti-K) undergoing liver transplant in South India: a team approach","volume":"14","author":"Sachan D","year":"2020","unstructured":"Sachan D, Tiwari AK, Dara R, Jothimani D, Kaliamoorthy I, Reddy SM, Rela M. Patient blood management in a patient with multiple red cell antibodies (anti-C, anti-e, and anti-K) undergoing liver transplant in South India: a team approach. Asian J Transfus Sci. 2020, 14:74-8. 10.4103\/ajts.AJTS_54_18","journal-title":"Asian J Transfus Sci"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03568.x","article-title":"Incomplete pretransfusion testing leads to surgical delays","volume":"52","author":"McWilliams B","year":"2012","unstructured":"McWilliams B, Yazer MH, Cramer J, Triulzi DJ, Waters JH. Incomplete pretransfusion testing leads to surgical delays. Transfusion. 2012, 52:2139-44; quiz 2145. 10.1111\/j.1537-2995.2012.03568.x","journal-title":"Transfusion"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.2450\/2014.0172-14","article-title":"Prevention of surgical delays by pre-admission type and screen in patients with scheduled surgical procedures: improved efficiency","volume":"13","author":"Pei Z","year":"2015","unstructured":"Pei Z, Szallasi A. Prevention of surgical delays by pre-admission type and screen in patients with scheduled surgical procedures: improved efficiency. Blood Transfus. 2015, 13:310-2. 10.2450\/2014.0172-14","journal-title":"Blood Transfus"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_296_19","article-title":"Prevalence of red blood cell antibodies in whole blood donors: a single-centre experience in north India","volume":"152","author":"Solanki A","year":"2020","unstructured":"Solanki A, Chandra T, Singh A. Prevalence of red blood cell antibodies in whole blood donors: a single-centre experience in north India. Indian J Med Res. 2020, 152:280-4. 10.4103\/ijmr.IJMR_296_19","journal-title":"Indian J Med Res"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1111\/j.1537-2995.2012.03582.x","article-title":"Red blood cell alloantibodies: a 45-year historical review at a rural tertiary care center","volume":"52","author":"Petras ML","year":"2012","unstructured":"Petras ML, Leach MK, Szczepiorkowski ZM, Dunbar NM. Red blood cell alloantibodies: a 45-year historical review at a rural tertiary care center. Transfusion. 2012, 52:1380-2. 10.1111\/j.1537-2995.2012.03582.x","journal-title":"Transfusion"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.21037\/atm-22-4999","article-title":"Analysis of anti-M antibody status and blood transfusion strategy in Hunan, China","volume":"10","author":"Wang S","year":"2022","unstructured":"Wang S, Wang J, Mo X, Wang Z, Wu Y, Liu F, Qu L. Analysis of anti-M antibody status and blood transfusion strategy in Hunan, China. Ann Transl Med. 2022, 10:1166. 10.21037\/atm-22-4999","journal-title":"Ann Transl Med"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1093\/labmed\/lmz078","article-title":"Anti-M-induced delayed hemolytic transfusion reaction","volume":"51","author":"Fadeyi EA","year":"2020","unstructured":"Fadeyi EA, Naal T, Green M, Simmons JH, Jones MR, Pomper GJ. Anti-M-induced delayed hemolytic transfusion reaction. Lab Med. 2020, 51:426-9. 10.1093\/labmed\/lmz078","journal-title":"Lab Med"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.102954","article-title":"Neonatal pure red cell aplasia due to anti-M","volume":"91","author":"Hinchliffe RF","year":"2006","unstructured":"Hinchliffe RF, Nolan B, Vora AJ, Stamps R. Neonatal pure red cell aplasia due to anti-M. Arch Dis Child Fetal Neonatal Ed. 2006, 91:F467-8. 10.1136\/adc.2006.102954","journal-title":"Arch Dis Child Fetal Neonatal Ed"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.4103\/0973-6247.150968","article-title":"Maternal anti-M induced hemolytic disease of newborn followed by prolonged anemia in newborn twins","volume":"9","author":"Arora S","year":"2015","unstructured":"Arora S, Doda V, Maria A, Kotwal U, Goyal S. Maternal anti-M induced hemolytic disease of newborn followed by prolonged anemia in newborn twins. Asian J Transfus Sci. 2015, 9:98-101. 10.4103\/0973-6247.150968","journal-title":"Asian J Transfus Sci"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/trf.17249","article-title":"A single-center, retrospective analysis of 17 cases of hemolytic disease of the fetus and newborn caused by anti-M antibodies","volume":"63","author":"He Y","year":"2023","unstructured":"He Y, Gao W, Li Y, Xu C, Wang Q. A single-center, retrospective analysis of 17 cases of hemolytic disease of the fetus and newborn caused by anti-M antibodies. Transfusion. 2023, 63:494-506. 10.1111\/trf.17249","journal-title":"Transfusion"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1111\/trf.16594","article-title":"Allo-anti-M: Detection peaks around 2\u2009years of age, but may be attenuated by red blood cell transfusion","volume":"61","author":"Tamai Y","year":"2021","unstructured":"Tamai Y, Ohto H, Yasuda H, et al.. Allo-anti-M: Detection peaks around 2\u2009years of age, but may be attenuated by red blood cell transfusion. Transfusion. 2021, 61:2718-26. 10.1111\/trf.16594","journal-title":"Transfusion"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.5348\/100067Z02AJ2022SR","article-title":"Spectrum of clinically significant anti-M antibody in patients requiring transfusion","volume":"12","author":"Jain A","year":"2022","unstructured":"Jain A, Singh L, Kaur A, Sharma RR. Spectrum of clinically significant anti-M antibody in patients requiring transfusion. Int J Blood Transfus Immunohematol. 2022, 12:1-5. 10.5348\/100067Z02AJ2022SR","journal-title":"Int J Blood Transfus Immunohematol"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1159\/000501861","article-title":"Pathophysiology of alloimmunization","volume":"47","author":"Molina-Aguilar R","year":"2020","unstructured":"Molina-Aguilar R, G\u00f3mez-Ruiz S, Vela-Ojeda J, Montiel-Cervantes LA, Reyes-Maldonado E. Pathophysiology of alloimmunization. Transfus Med Hemother. 2020, 47:152-9. 10.1159\/000501861","journal-title":"Transfus Med Hemother"},{"key":"ref24","article-title":"Distribution and prevalence of ABO and Rh phenotype blood groups in eastern India","volume":"4","author":"Mahapatra S","year":"2014","unstructured":"Mahapatra S, Sahoo D, Patjoshi S, Sahu A, Parida P, Mishra S. Distribution and prevalence of ABO and Rh phenotype blood groups in eastern India. J Pharm Biomed Sci. 2014, 4:712-4.","journal-title":"J Pharm Biomed Sci"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.4103\/0971-6866.38979","article-title":"Bombay phenotype in Orissa: what could we make out of it?","volume":"13","author":"Ghosh K","year":"2007","unstructured":"Ghosh K, Vasantha K. Bombay phenotype in Orissa: what could we make out of it?. Indian J Hum Genet. 2007, 13:79-80. 10.4103\/0971-6866.38979","journal-title":"Indian J Hum Genet"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1111\/vox.12168","article-title":"MN typing discrepancies based on GYPA-B-A hybrid","volume":"107","author":"Polin H","year":"2014","unstructured":"Polin H, Danzer M, Reiter A, Brisner M, Gaszner W, Weinberger J, Gabriel C. MN typing discrepancies based on GYPA-B-A hybrid. Vox Sang. 2014, 107:393-8. 10.1111\/vox.12168","journal-title":"Vox Sang"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.21307\/immunohematology-2019-377","article-title":"Molecular basis of MNS blood group variants","volume":"22","author":"Palacajornsuk P","year":"2006","unstructured":"Palacajornsuk P. Molecular basis of MNS blood group variants. Immunohematology. 2006, 22:171-82. 10.21307\/immunohematology-2019-377","journal-title":"Immunohematology"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.21037\/aob-21-9","article-title":"Glycophorins and the MNS blood group system: a narrative review","volume":"6","author":"Lopez GH","year":"2021","unstructured":"Lopez GH, Hyland CA, Flower RL. Glycophorins and the MNS blood group system: a narrative review. Ann Blood. 2021, 6:10.21037\/aob-21-9","journal-title":"Ann Blood"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V84.7.2340.2340","article-title":"Anti-M monoclonal antibodies cross-reacting with variant Mg antigen: an example of modulation of antigenic properties of peptide by its glycosylation","volume":"84","author":"Jaskiewicz E","year":"1994","unstructured":"Jaskiewicz E, Czerwinski M, Syper D, Lisowska E. Anti-M monoclonal antibodies cross-reacting with variant Mg antigen: an example of modulation of antigenic properties of peptide by its glycosylation. Blood. 1994, 84:2340-5. 10.1182\/blood.V84.7.2340.2340","journal-title":"Blood"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/367597-anti-m-antibody-in-blood-transfusion-an-underestimated-factor-in-service-delays-and-expenditures","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,5,29]],"date-time":"2025-05-29T04:00:02Z","timestamp":1748491202000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/367597-anti-m-antibody-in-blood-transfusion-an-underestimated-factor-in-service-delays-and-expenditures"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,5,28]]},"references-count":29,"URL":"https:\/\/doi.org\/10.7759\/cureus.85004","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,5,28]]}}}