{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T00:36:20Z","timestamp":1788568580272,"version":"build-2803163510"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,5]]},"DOI":"10.7759\/cureus.85420","type":"journal-article","created":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T18:06:32Z","timestamp":1749146792000},"source":"Crossref","is-referenced-by-count":3,"title":["Multidrug-Resistant Candida in Bloodstream Infections: A Growing Concern in Indian Healthcare"],"prefix":"10.7759","author":[{"given":"Shailendra  K","family":"Yadav","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D","family":"Himanshu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prashant","family":"Gupta","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anuradha","family":"Nischal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Virendra","family":"Atam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wahid","family":"Ali","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ambuj","family":"Yadav","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay","family":"Sonkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vivek","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3390\/jof11030217","article-title":"Epidemiology and clinical features of Candida bloodstream infections: a 10-year retrospective study in a Korean teaching hospital","volume":"11","author":"Yu SN","year":"2025","unstructured":"Yu SN, Hong SI, Park JW, Jeon MH, Cho OH. Epidemiology and clinical features of Candida bloodstream infections: a 10-year retrospective study in a Korean teaching hospital. J Fungi (Basel). 2025, 11:10.3390\/jof11030217","journal-title":"J Fungi (Basel)"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra1315399","article-title":"Invasive candidiasis","volume":"373","author":"Kullberg BJ","year":"2015","unstructured":"Kullberg BJ, Arendrup MC. Invasive candidiasis. N Engl J Med. 2015, 373:1445-56. 10.1056\/NEJMra1315399","journal-title":"N Engl J Med"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/civ933","article-title":"Clinical practice guidelines for the management of candidiasis: 2016 update by the Infectious Diseases Society of America","volume":"62","author":"Pappas PG","year":"2016","unstructured":"Pappas PG, Kauffman CA, Andes DR, et al.. Clinical practice guidelines for the management of candidiasis: 2016 update by the Infectious Diseases Society of America. Clin Infect Dis. 2016, 62:e1-50. 10.1093\/cid\/civ933","journal-title":"Clin Infect Dis"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1586\/14787210.4.5.875","article-title":"Candida infections in the intensive care unit: epidemiology, risk factors and therapeutic strategies","volume":"4","author":"Bassetti M","year":"2006","unstructured":"Bassetti M, Righi E, Tumbarello M, Di Biagio A, Rosso R, Viscoli C. Candida infections in the intensive care unit: epidemiology, risk factors and therapeutic strategies. Expert Rev Anti Infect Ther. 2006, 4:875-85. 10.1586\/14787210.4.5.875","journal-title":"Expert Rev Anti Infect Ther"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00091-13","article-title":"Molecular and nonmolecular diagnostic methods for invasive fungal infections","volume":"27","author":"Arvanitis M","year":"2014","unstructured":"Arvanitis M, Anagnostou T, Fuchs BB, Caliendo AM, Mylonakis E. Molecular and nonmolecular diagnostic methods for invasive fungal infections. Clin Microbiol Rev. 2014, 27:490-526. 10.1128\/CMR.00091-13","journal-title":"Clin Microbiol Rev"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1099\/jmm.0.045054-0","article-title":"Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options","volume":"62","author":"Sardi JC","year":"2013","unstructured":"Sardi JC, Scorzoni L, Bernardi T, Fusco-Almeida AM, Mendes Giannini MJ. Candida species: current epidemiology, pathogenicity, biofilm formation, natural antifungal products and new therapeutic options. J Med Microbiol. 2013, 62:10-24. 10.1099\/jmm.0.045054-0","journal-title":"J Med Microbiol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1007\/s00134-014-3603-2","article-title":"Incidence, characteristics and outcome of ICU-acquired candidemia in India","volume":"41","author":"Chakrabarti A","year":"2015","unstructured":"Chakrabarti A, Sood P, Rudramurthy SM, et al.. Incidence, characteristics and outcome of ICU-acquired candidemia in India. Intensive Care Med. 2015, 41:285-95. 10.1007\/s00134-014-3603-2","journal-title":"Intensive Care Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1006290","article-title":"Candida auris: a rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally","volume":"13","author":"Chowdhary A","year":"2017","unstructured":"Chowdhary A, Sharma C, Meis JF. Candida auris: a rapidly emerging cause of hospital-acquired multidrug-resistant fungal infections globally. PLoS Pathog. 2017, 13:e1006290. 10.1371\/journal.ppat.1006290","journal-title":"PLoS Pathog"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_134_20","article-title":"Candidemia in intensive care units: a major health concern in India","volume":"151","author":"Sharma A","year":"2020","unstructured":"Sharma A, Gupta N. Candidemia in intensive care units: a major health concern in India. Indian J Med Res. 2020, 151:441-6. 10.4103\/ijmr.IJMR_134_20","journal-title":"Indian J Med Res"},{"key":"ref10","article-title":"Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008","volume":"3","author":"Pfaller MA","year":"2014","unstructured":"Pfaller MA, Andes DR, Diekema DJ, et al.. Epidemiology and outcomes of invasive candidiasis due to non-albicans species of Candida in 2,496 patients: data from the Prospective Antifungal Therapy (PATH) registry 2004-2008. PloS one. 2014, 3:101510.","journal-title":"PloS one"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00029-06","article-title":"Epidemiology of invasive candidiasis: a persistent public health problem","volume":"20","author":"Pfaller MA","year":"2007","unstructured":"Pfaller MA, Diekema DJ. Epidemiology of invasive candidiasis: a persistent public health problem. Clin Microbiol Rev. 2007, 20:133-63. 10.1128\/CMR.00029-06","journal-title":"Clin Microbiol Rev"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(17)30316-X","article-title":"The global problem of antifungal resistance: prevalence, mechanisms, and management","volume":"17","author":"Perlin DS","year":"2017","unstructured":"Perlin DS, Rautemaa-Richardson R, Alastruey-Izquierdo A. The global problem of antifungal resistance: prevalence, mechanisms, and management. Lancet Infect Dis. 2017, 17:383-92. 10.1016\/S1473-3099(17)30316-X","journal-title":"Lancet Infect Dis"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-019-4710-z","article-title":"Antifungal resistance in patients with Candidaemia: a retrospective cohort study","volume":"20","author":"Aldardeer NF","year":"2020","unstructured":"Aldardeer NF, Albar H, Al-Attas M, Eldali A, Qutub M, Hassanien A, Alraddadi B. Antifungal resistance in patients with Candidaemia: a retrospective cohort study. BMC Infect Dis. 2020, 20:55. 10.1186\/s12879-019-4710-z","journal-title":"BMC Infect Dis"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.01909-17","article-title":"Diagnosing invasive candidiasis","volume":"56","author":"Clancy CJ","year":"2018","unstructured":"Clancy CJ, Nguyen MH. Diagnosing invasive candidiasis. J Clin Microbiol. 2018, 56:10.1128\/JCM.01909-17","journal-title":"J Clin Microbiol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix131","article-title":"Multidrug-resistant Candida: epidemiology, molecular mechanisms, and treatment","volume":"216","author":"Arendrup MC","year":"2017","unstructured":"Arendrup MC, Patterson TF. Multidrug-resistant Candida: epidemiology, molecular mechanisms, and treatment. J Infect Dis. 2017, 216:S445-51. 10.1093\/infdis\/jix131","journal-title":"J Infect Dis"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.3390\/jof9101012","article-title":"Paradigm shift: Candida parapsilosis sensu stricto as the most prevalent candida species isolated from bloodstream infections with increasing azole-non-susceptibility rates: trends from 2015-2022 survey","volume":"9","author":"Franconi I","year":"2023","unstructured":"Franconi I, Rizzato C, Tavanti A, Falcone M, Lupetti A. Paradigm shift: Candida parapsilosis sensu stricto as the most prevalent candida species isolated from bloodstream infections with increasing azole-non-susceptibility rates: trends from 2015-2022 survey. J Fungi (Basel). 2023, 9:10.3390\/jof9101012","journal-title":"J Fungi (Basel)"},{"key":"ref17","article-title":"Risk factors for candidemia: a comprehensive review","volume":"82","author":"Cheng MP","year":"2019","unstructured":"Cheng MP, Paquette K, Landry JS, et al.. Risk factors for candidemia: a comprehensive review. Int J Infect Dis. 2019, 82:88-94.","journal-title":"Int J Infect Dis"},{"key":"ref18","article-title":"Prevalence of Candida species and antifungal susceptibility patterns in patients with candidemia in a tertiary care hospital in India","volume":"13","author":"Kaur M","year":"2020","unstructured":"Kaur M, Chakrabarti A, Shankarnarayan SA, et al.. Prevalence of Candida species and antifungal susceptibility patterns in patients with candidemia in a tertiary care hospital in India. Infect Drug Resist. 2020, 13:1211-7.","journal-title":"Infect Drug Resist"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1177\/11786337211026927","article-title":"Candida bloodstream infections: changes in epidemiology and increase in drug resistance","volume":"14","author":"Kotey FC","year":"2021","unstructured":"Kotey FC, Dayie NT, Tetteh-Uarcoo PB, Donkor ES. Candida bloodstream infections: changes in epidemiology and increase in drug resistance. Infect Dis (Auckl). 2021, 14:11786337211026927. 10.1177\/11786337211026927","journal-title":"Infect Dis (Auckl)"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1017\/ice.2019.296","article-title":"Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: summary of data reported to the National Healthcare Safety Network, 2015-2017","volume":"41","author":"Weiner-Lastinger LM","year":"2020","unstructured":"Weiner-Lastinger LM, Abner S, Edwards JR, et al.. Antimicrobial-resistant pathogens associated with adult healthcare-associated infections: summary of data reported to the National Healthcare Safety Network, 2015-2017. Infect Control Hosp Epidemiol. 2020, 41:1-18. 10.1017\/ice.2019.296","journal-title":"Infect Control Hosp Epidemiol"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.4103\/0974-2727.141506","article-title":"The epidemiological profile of candidemia at an Indian trauma care center","volume":"6","author":"Tak V","year":"2014","unstructured":"Tak V, Mathur P, Varghese P, Gunjiyal J, Xess I, Misra MC. The epidemiological profile of candidemia at an Indian trauma care center. J Lab Physicians. 2014, 6:96-101. 10.4103\/0974-2727.141506","journal-title":"J Lab Physicians"},{"key":"ref22","article-title":"A case report with dual diagnosis of candidiasis in a patient with uncontrolled diabetes mellitus","volume":"31","author":"Dadgal KV","year":"2024","unstructured":"Dadgal KV, Mohod S. A case report with dual diagnosis of candidiasis in a patient with uncontrolled diabetes mellitus. Cureus. 2024, 31:16.","journal-title":"Cureus"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/353685-multidrug-resistant-candida-in-bloodstream-infections-a-growing-concern-in-indian-healthcare","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,5]],"date-time":"2025-06-05T18:06:33Z","timestamp":1749146793000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/353685-multidrug-resistant-candida-in-bloodstream-infections-a-growing-concern-in-indian-healthcare"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,5]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.85420","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,5]]}}}