{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T04:03:34Z","timestamp":1749355414977,"version":"3.41.0"},"reference-count":15,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,7]]},"DOI":"10.7759\/cureus.85528","type":"journal-article","created":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T20:25:57Z","timestamp":1749327957000},"source":"Crossref","is-referenced-by-count":0,"title":["Systemic Lupus Erythematosus-Associated Thrombotic Thrombocytopenic Purpura: A Case Report"],"prefix":"10.7759","author":[{"given":"Ounci","family":"Es-Saad","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adil","family":"Zyani","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ayman","family":"Bouchlaghem","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajae","family":"Alkouh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Smael","family":"Labib","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1186\/s13023-020-01510-9","article-title":"Immune-mediated thrombotic thrombocytopenic purpura in patients with and without systemic lupus erythematosus: a retrospective study","volume":"15","author":"Yue C","year":"2020","unstructured":"Yue C, Su J, Fan X, et al.. Immune-mediated thrombotic thrombocytopenic purpura in patients with and without systemic lupus erythematosus: a retrospective study. Orphanet J Rare Dis. 2020, 15:225. 10.1186\/s13023-020-01510-9","journal-title":"Orphanet J Rare Dis"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0033029","article-title":"Acquired idiopathic ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in a population from Japan","volume":"7","author":"Matsumoto M","year":"2012","unstructured":"Matsumoto M, Bennett CL, Isonishi A, et al.. Acquired idiopathic ADAMTS13 activity deficient thrombotic thrombocytopenic purpura in a population from Japan. PLoS One. 2012, 7:e33029. 10.1371\/journal.pone.0033029","journal-title":"PLoS One"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/s0049-0172(98)80023-1","article-title":"Review of thrombotic thrombocytopenic purpura in the setting of systemic lupus erythematosus","volume":"28","author":"Musio F","year":"1998","unstructured":"Musio F, Bohen EM, Yuan CM, et al.. Review of thrombotic thrombocytopenic purpura in the setting of systemic lupus erythematosus. Semin Arthritis Rheum. 1998, 28:1-19. 10.1016\/s0049-0172(98)80023-1","journal-title":"Semin Arthritis Rheum"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1186\/s12882-020-01888-5","article-title":"A systematic review of the role of eculizumab in systemic lupus erythematosus-associated thrombotic microangiopathy","volume":"21","author":"Wright RD","year":"2020","unstructured":"Wright RD, Bannerman F, Beresford MW, Oni L. A systematic review of the role of eculizumab in systemic lupus erythematosus-associated thrombotic microangiopathy. BMC Nephrol. 2020, 21:245. 10.1186\/s12882-020-01888-5","journal-title":"BMC Nephrol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-019-0641-y","article-title":"Clinical features and prognosis of patients with thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus: a review of 25 cases","volume":"45","author":"Li J","year":"2019","unstructured":"Li J, Jiang JJ, Wang CY, et al.. Clinical features and prognosis of patients with thrombotic thrombocytopenic purpura associated with systemic lupus erythematosus: a review of 25 cases. Ital J Pediatr. 2019, 45:55. 10.1186\/s13052-019-0641-y","journal-title":"Ital J Pediatr"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(17)30026-1","article-title":"Derivation and external validation of the PLASMIC score","volume":"4","author":"Bendapudi PK","year":"2017","unstructured":"Bendapudi PK, Hurwitz S, Fry A, et al.. Derivation and external validation of the PLASMIC score. Lancet Haematol. 2017, 4:157-64. 10.1016\/S2352-3026(17)30026-1","journal-title":"Lancet Haematol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra020528","article-title":"Thrombotic microangiopathies","volume":"347","author":"Moake JL","year":"2002","unstructured":"Moake JL. Thrombotic microangiopathies. N Engl J Med. 2002, 347:589-600. 10.1056\/NEJMra020528","journal-title":"N Engl J Med"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1161\/01.str.8.6.719","article-title":"Neurological manifestations of systemic lupus erythematosus and thrombotic thrombocytopenic purpura","volume":"8","author":"Petz LD","year":"1977","unstructured":"Petz LD. Neurological manifestations of systemic lupus erythematosus and thrombotic thrombocytopenic purpura. Stroke. 1977, 8:719-22. 10.1161\/01.str.8.6.719","journal-title":"Stroke"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3390\/idr15040035","article-title":"Anaplasma phagocytophilum encephalitis: a case report and literature review of neurologic manifestations of anaplasmosis","volume":"15","author":"Cosiquien RJ","year":"2023","unstructured":"Cosiquien RJ, Stojiljkovic N, Nordstrom CW, Amadi E, Lutwick L, Dumic I. Anaplasma phagocytophilum encephalitis: a case report and literature review of neurologic manifestations of anaplasmosis. Infect Dis Rep. 2023, 15:354-9. 10.3390\/idr15040035","journal-title":"Infect Dis Rep"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-03-341131","article-title":"A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura","volume":"118","author":"Scully M","year":"2011","unstructured":"Scully M, McDonald V, Cavenagh J, Hunt BJ, Longair I, Cohen H, Machin SJ. A phase 2 study of the safety and efficacy of rituximab with plasma exchange in acute acquired thrombotic thrombocytopenic purpura. Blood. 2011, 118:1746-53. 10.1182\/blood-2011-03-341131","journal-title":"Blood"},{"key":"ref11","article-title":"Neurologic manifestations of thrombotic thrombocytopenic purpura: a systematic review","volume":"49","author":"Kello N","year":"2019","unstructured":"Kello N, Anderson M, Farge D, et al.. Neurologic manifestations of thrombotic thrombocytopenic purpura: a systematic review. Semin Arthritis Rheum. 2019, 49:585-90.","journal-title":"Semin Arthritis Rheum"},{"key":"ref12","doi-asserted-by":"crossref","DOI":"10.1016\/0049-0172(94)90073-6","article-title":"Systemic lupus erythematosus complicated by thrombotic microangiopathy","volume":"24","author":"Jain R","year":"1994","unstructured":"Jain R, Chartash R, Susin M, et al.. Systemic lupus erythematosus complicated by thrombotic microangiopathy. Semin Arthritis Rheum. 1994, 24:173-82.","journal-title":"Semin Arthritis Rheum"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.semarthrit.2018.11.005","article-title":"Secondary thrombotic microangiopathy in systemic lupus erythematosus and antiphospholipid syndrome, the role of complement and use of eculizumab: case series and review of literature","volume":"49","author":"Kello N","year":"2019","unstructured":"Kello N, Khoury LE, Marder G, Furie R, Zapantis E, Horowitz DL. Secondary thrombotic microangiopathy in systemic lupus erythematosus and antiphospholipid syndrome, the role of complement and use of eculizumab: case series and review of literature. Semin Arthritis Rheum. 2019, 49:74-83. 10.1016\/j.semarthrit.2018.11.005","journal-title":"Semin Arthritis Rheum"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2022.1097528","article-title":"Case report: thrombotic microangiopathy concomitant with macrophage activation syndrome in systemic lupus erythematosus refractory to conventional treatment successfully treated with eculizumab","volume":"9","author":"Yamaguchi M","year":"2022","unstructured":"Yamaguchi M, Mizuno M, Kitamura F, et al.. Case report: thrombotic microangiopathy concomitant with macrophage activation syndrome in systemic lupus erythematosus refractory to conventional treatment successfully treated with eculizumab. Front Med (Lausanne). 2022, 9:1097528. 10.3389\/fmed.2022.1097528","journal-title":"Front Med (Lausanne)"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1097\/01.md.0000133622.03370.07","article-title":"Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement","volume":"83","author":"Coppo P","year":"2004","unstructured":"Coppo P, Bengoufa D, Veyradier A, et al.. Severe ADAMTS13 deficiency in adult idiopathic thrombotic microangiopathies defines a subset of patients characterized by various autoimmune manifestations, lower platelet count, and mild renal involvement. Medicine (Baltimore). 2004, 83:233-44. 10.1097\/01.md.0000133622.03370.07","journal-title":"Medicine (Baltimore)"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/360578-systemic-lupus-erythematosus-associated-thrombotic-thrombocytopenic-purpura-a-case-report","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,7]],"date-time":"2025-06-07T20:25:58Z","timestamp":1749327958000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/360578-systemic-lupus-erythematosus-associated-thrombotic-thrombocytopenic-purpura-a-case-report"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,7]]},"references-count":15,"URL":"https:\/\/doi.org\/10.7759\/cureus.85528","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,7]]}}}