{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T02:40:04Z","timestamp":1749350404483,"version":"3.41.0"},"reference-count":20,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,7]]},"DOI":"10.7759\/cureus.85536","type":"journal-article","created":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T02:17:26Z","timestamp":1749349046000},"source":"Crossref","is-referenced-by-count":0,"title":["Stereotactic Body Radiation Therapy for Intrahepatic Graft Recurrences of Hepatocellular Carcinoma After Liver Transplantation: A Report of Two Cases"],"prefix":"10.7759","author":[{"given":"Alexander","family":"Piening","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alyssa","family":"Capizzi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeevin","family":"Shahi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.14218\/JCTH.2023.00356","article-title":"Hepatocellular carcinoma incidence and mortality in the USA by sex, age, and race: a nationwide analysis of two decades","volume":"12","author":"Abboud Y","year":"2024","unstructured":"Abboud Y, Ismail M, Khan H, Medina-Morales E, Alsakarneh S, Jaber F, Pyrsopoulos NT. Hepatocellular carcinoma incidence and mortality in the USA by sex, age, and race: a nationwide analysis of two decades. J Clin Transl Hepatol. 2024, 12:172-81. 10.14218\/JCTH.2023.00356","journal-title":"J Clin Transl Hepatol"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1111\/liv.14154","article-title":"The concept of therapeutic hierarchy for patients with hepatocellular carcinoma: a multicenter cohort study","volume":"39","author":"Vitale A","year":"2019","unstructured":"Vitale A, Farinati F, Pawlik TM, et al.. The concept of therapeutic hierarchy for patients with hepatocellular carcinoma: a multicenter cohort study. Liver Int. 2019, 39:1478-89. 10.1111\/liv.14154","journal-title":"Liver Int"},{"key":"ref3","unstructured":"National Comprehensive Cancer Network. Hepatocellular Carcinoma Version 4.2024. (2025). Accessed: February 8, 2025: https:\/\/www.nccn.org\/guidelines\/guidelines-detail?category=1&id=1514."},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i39.11185","article-title":"Managements of recurrent hepatocellular carcinoma after liver transplantation: a systematic review","volume":"21","author":"de'Angelis N","year":"2015","unstructured":"de'Angelis N, Landi F, Carra MC, Azoulay D. Managements of recurrent hepatocellular carcinoma after liver transplantation: a systematic review. World J Gastroenterol. 2015, 21:11185-98. 10.3748\/wjg.v21.i39.11185","journal-title":"World J Gastroenterol"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-014-4273-6","article-title":"Benefit of treating hepatocellular carcinoma recurrence after liver transplantation and analysis of prognostic factors for survival in a large Euro-American series","volume":"22","author":"Sapisochin G","year":"2015","unstructured":"Sapisochin G, Goldaracena N, Astete S, et al.. Benefit of treating hepatocellular carcinoma recurrence after liver transplantation and analysis of prognostic factors for survival in a large Euro-American series. Ann Surg Oncol. 2015, 22:2286-94. 10.1245\/s10434-014-4273-6","journal-title":"Ann Surg Oncol"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.3350\/cmh.2021.0217","article-title":"The management of post-transplantation recurrence of hepatocellular carcinoma","volume":"28","author":"Rajendran L","year":"2022","unstructured":"Rajendran L, Ivanics T, Claasen MP, Muaddi H, Sapisochin G. The management of post-transplantation recurrence of hepatocellular carcinoma. Clin Mol Hepatol. 2022, 28:1-16. 10.3350\/cmh.2021.0217","journal-title":"Clin Mol Hepatol"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.12998\/wjcc.v8.i13.2758","article-title":"Initial experience with stereotactic body radiotherapy for intrahepatic hepatocellular carcinoma recurrence after liver transplantation","volume":"8","author":"Au KP","year":"2020","unstructured":"Au KP, Chiang CL, Chan AC, Cheung TT, Lo CM, Chok KS. Initial experience with stereotactic body radiotherapy for intrahepatic hepatocellular carcinoma recurrence after liver transplantation. World J Clin Cases. 2020, 8:2758-68. 10.12998\/wjcc.v8.i13.2758","journal-title":"World J Clin Cases"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-015-4579-z","article-title":"A phase I dose-escalation trial of single-fraction stereotactic radiation therapy for liver metastases","volume":"23","author":"Meyer JJ","year":"2016","unstructured":"Meyer JJ, Foster RD, Lev-Cohain N, et al.. A phase I dose-escalation trial of single-fraction stereotactic radiation therapy for liver metastases. Ann Surg Oncol. 2016, 23:218-24. 10.1245\/s10434-015-4579-z","journal-title":"Ann Surg Oncol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2021.09.027","article-title":"A story of hypofractionation and the table on the wall","volume":"112","author":"Timmerman R","year":"2022","unstructured":"Timmerman R. A story of hypofractionation and the table on the wall. Int J Radiat Oncol Biol Phys. 2022, 112:4-21. 10.1016\/j.ijrobp.2021.09.027","journal-title":"Int J Radiat Oncol Biol Phys"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3390\/cancers13194882","article-title":"Management of hepatocellular carcinoma recurrence after liver transplantation","volume":"13","author":"Pelizzaro F","year":"2021","unstructured":"Pelizzaro F, Gambato M, Gringeri E, et al.. Management of hepatocellular carcinoma recurrence after liver transplantation. Cancers (Basel). 2021, 13:4882. 10.3390\/cancers13194882","journal-title":"Cancers (Basel)"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.20.00818","article-title":"Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial","volume":"38","author":"Palma DA","year":"2020","unstructured":"Palma DA, Olson R, Harrow S, et al.. Stereotactic ablative radiotherapy for the comprehensive treatment of oligometastatic cancers: long-term results of the SABR-COMET phase II randomized trial. J Clin Oncol. 2020, 38:2830-8. 10.1200\/JCO.20.00818","journal-title":"J Clin Oncol"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jss.2015.07.033","article-title":"Is radiofrequency ablation applicable for recurrent hepatocellular carcinoma after liver transplantation?","volume":"200","author":"Huang J","year":"2016","unstructured":"Huang J, Yan L, Wu H, Yang J, Liao M, Zeng Y. Is radiofrequency ablation applicable for recurrent hepatocellular carcinoma after liver transplantation?. J Surg Res. 2016, 200:122-30. 10.1016\/j.jss.2015.07.033","journal-title":"J Surg Res"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1200\/JCO-24-01532","article-title":"Radiofrequency ablation versus stereotactic body radiotherapy for recurrent small hepatocellular carcinoma: a randomized, open-label, controlled trial","volume":"43","author":"Xi M","year":"2025","unstructured":"Xi M, Yang Z, Hu L, et al.. Radiofrequency ablation versus stereotactic body radiotherapy for recurrent small hepatocellular carcinoma: a randomized, open-label, controlled trial. J Clin Oncol. 2025, 43:1073-82. 10.1200\/JCO-24-01532","journal-title":"J Clin Oncol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2018.12.005","article-title":"Clinical feasibility and efficacy of stereotactic body radiotherapy for hepatocellular carcinoma: a systematic review and meta-analysis of observational studies","volume":"131","author":"Rim CH","year":"2019","unstructured":"Rim CH, Kim HJ, Seong J. Clinical feasibility and efficacy of stereotactic body radiotherapy for hepatocellular carcinoma: a systematic review and meta-analysis of observational studies. Radiother Oncol. 2019, 131:135-44. 10.1016\/j.radonc.2018.12.005","journal-title":"Radiother Oncol"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1290691","article-title":"Overall survival in advanced hepatocellular carcinoma treated with concomitant systemic therapy and stereotactic body radiation therapy or systemic therapy alone","volume":"13","author":"Piening A","year":"2023","unstructured":"Piening A, Swaminath A, Dombrowski J, Teague RM, Al-Hammadi N, Shahi J. Overall survival in advanced hepatocellular carcinoma treated with concomitant systemic therapy and stereotactic body radiation therapy or systemic therapy alone. Front Oncol. 2023, 13:1290691. 10.3389\/fonc.2023.1290691","journal-title":"Front Oncol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2024.5403","article-title":"Stereotactic body radiotherapy vs sorafenib alone in hepatocellular carcinoma: the NRG oncology\/RTOG 1112 phase 3 randomized clinical trial","volume":"11","author":"Dawson LA","year":"2025","unstructured":"Dawson LA, Winter KA, Knox JJ, et al.. Stereotactic body radiotherapy vs sorafenib alone in hepatocellular carcinoma: the NRG oncology\/RTOG 1112 phase 3 randomized clinical trial. JAMA Oncol. 2025, 11:136-44. 10.1001\/jamaoncol.2024.5403","journal-title":"JAMA Oncol"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.7759\/cureus.9988","article-title":"Stereotactic body radiation therapy for recurrent, isolated hepatocellular carcinoma lymph node metastasis with or without prior liver transplantation","volume":"12","author":"Walburn T","year":"2020","unstructured":"Walburn T, Moon AM, Hayashi PH, et al.. Stereotactic body radiation therapy for recurrent, isolated hepatocellular carcinoma lymph node metastasis with or without prior liver transplantation. Cureus. 2020, 12:e9988. 10.7759\/cureus.9988","journal-title":"Cureus"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.3390\/cancers15184574","article-title":"Immunotherapy and liver transplantation: a narrative review of basic and clinical data","volume":"15","author":"Wassmer CH","year":"2023","unstructured":"Wassmer CH, El Hajji S, Papazarkadas X, Compagnon P, Tabrizian P, Lacotte S, Toso C. Immunotherapy and liver transplantation: a narrative review of basic and clinical data. Cancers (Basel). 2023, 15:4574. 10.3390\/cancers15184574","journal-title":"Cancers (Basel)"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2015.01.001","article-title":"Survival of patients treated with sorafenib for hepatocellular carcinoma recurrence after liver transplantation: a systematic review and meta-analysis","volume":"47","author":"Mancuso A","year":"2015","unstructured":"Mancuso A, Mazzola A, Cabibbo G, et al.. Survival of patients treated with sorafenib for hepatocellular carcinoma recurrence after liver transplantation: a systematic review and meta-analysis. Dig Liver Dis. 2015, 47:324-30. 10.1016\/j.dld.2015.01.001","journal-title":"Dig Liver Dis"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1111\/ajt.15551","article-title":"Preliminary experience on safety of regorafenib after sorafenib failure in recurrent hepatocellular carcinoma after liver transplantation","volume":"19","author":"Iavarone M","year":"2019","unstructured":"Iavarone M, Invernizzi F, Czauderna C, et al.. Preliminary experience on safety of regorafenib after sorafenib failure in recurrent hepatocellular carcinoma after liver transplantation. Am J Transplant. 2019, 19:3176-84. 10.1111\/ajt.15551","journal-title":"Am J Transplant"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/344409-stereotactic-body-radiation-therapy-for-intrahepatic-graft-recurrences-of-hepatocellular-carcinoma-after-liver-transplantation-a-report-of-two-cases","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,8]],"date-time":"2025-06-08T02:17:27Z","timestamp":1749349047000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/344409-stereotactic-body-radiation-therapy-for-intrahepatic-graft-recurrences-of-hepatocellular-carcinoma-after-liver-transplantation-a-report-of-two-cases"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,7]]},"references-count":20,"URL":"https:\/\/doi.org\/10.7759\/cureus.85536","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,7]]}}}