{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,6,12]],"date-time":"2025-06-12T04:12:59Z","timestamp":1749701579496,"version":"3.41.0"},"reference-count":22,"publisher":"Springer Science and Business Media LLC","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2025,6,11]]},"DOI":"10.7759\/cureus.85778","type":"journal-article","created":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T15:59:11Z","timestamp":1749657551000},"source":"Crossref","is-referenced-by-count":0,"title":["Tracking the Invisible War: Automated Profiling of Multidrug-Resistant Pathogens in a Tertiary Care Teaching Hospital in Central India"],"prefix":"10.7759","author":[{"given":"Smita V","family":"Mohod","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dilip S","family":"Gedam","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arya L","family":"Rajan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ravindra  K","family":"Khadse","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Riya","family":"John","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"297","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(21)02724-0","article-title":"Global burden of bacterial antimicrobial resistance in 2019: a systematic analysis","volume":"399","year":"2022","unstructured":"Global burden of bacterial antimicrobial resistance in 2019. a systematic analysis. Lancet. 2022, 399:629-55. 10.1016\/S0140-6736(21)02724-0","journal-title":"Lancet"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics11040427","article-title":"Antimicrobial susceptibility testing: a comprehensive review of currently used methods","volume":"11","author":"Gajic I","year":"2022","unstructured":"Gajic I, Kabic J, Kekic D, et al.. Antimicrobial susceptibility testing: a comprehensive review of currently used methods. Antibiotics (Basel). 2022, 11:427. 10.3390\/antibiotics11040427","journal-title":"Antibiotics (Basel)"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/j.diagmicrobio.2006.12.008","article-title":"Laboratory-based evaluation of the colorimetric VITEK-2 Compact system for species identification and of the Advanced Expert System for detection of antimicrobial resistances: VITEK-2 Compact system identification and antimicrobial susceptibility testing","volume":"58","author":"Nakasone I","year":"2007","unstructured":"Nakasone I, Kinjo T, Yamane N, Kisanuki K, Shiohira CM. Laboratory-based evaluation of the colorimetric VITEK-2 Compact system for species identification and of the Advanced Expert System for detection of antimicrobial resistances: VITEK-2 Compact system identification and antimicrobial susceptibility testing. Diagn Microbiol Infect Dis. 2007, 58:191-8. 10.1016\/j.diagmicrobio.2006.12.008","journal-title":"Diagn Microbiol Infect Dis"},{"key":"ref4","unstructured":"CLSI M100. Performance Standards for Antimicrobial Susceptibility Testing. (2025). Accessed. March 1, 2025: https:\/\/clsi.org\/standards\/products\/microbiology\/documents\/m100\/.."},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-018-0404-3","article-title":"Incidence and outcomes of multidrug-resistant gram-negative bacteria infections in intensive care unit from Nepal- a prospective cohort study","volume":"7","author":"Siwakoti S","year":"2018","unstructured":"Siwakoti S, Subedi A, Sharma A, Baral R, Bhattarai NR, Khanal B. Incidence and outcomes of multidrug-resistant gram-negative bacteria infections in intensive care unit from Nepal- a prospective cohort study. Antimicrob Resist Infect Control. 2018, 7:114. 10.1186\/s13756-018-0404-3","journal-title":"Antimicrob Resist Infect Control"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-025-00714-y","article-title":"Prevalence and associated factors of multi-drug resistant bacteria among different clinical specimens at wad Medani, Sudan: a four-year, cross-sectional study","volume":"15","author":"Hamadalneel YB","year":"2025","unstructured":"Hamadalneel YB, Eltoum SF, Almustafa ZM, et al.. Prevalence and associated factors of multi-drug resistant bacteria among different clinical specimens at wad Medani, Sudan: a four-year, cross-sectional study. Sci Rep. 2025, 15:15596. 10.1038\/s41598-025-00714-y","journal-title":"Sci Rep"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1186\/s13756-017-0222-z","article-title":"High burden of antimicrobial resistance among gram negative bacteria causing healthcare associated infections in a critical care unit of Nepal","volume":"6","author":"Parajuli NP","year":"2017","unstructured":"Parajuli NP, Acharya SP, Mishra SK, Parajuli K, Rijal BP, Pokhrel BM. High burden of antimicrobial resistance among gram negative bacteria causing healthcare associated infections in a critical care unit of Nepal. Antimicrob Resist Infect Control. 2017, 6:67. 10.1186\/s13756-017-0222-z","journal-title":"Antimicrob Resist Infect Control"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.4103\/0377-4929.134698","article-title":"Prevalence of blaTEM , blaSHV and blaCTX-M genes in clinical isolates of Escherichia coli and Klebsiella pneumoniae from Northeast India","volume":"57","author":"Bora A","year":"2014","unstructured":"Bora A, Hazarika NK, Shukla SK, Prasad KN, Sarma JB, Ahmed G. Prevalence of blaTEM , blaSHV and blaCTX-M genes in clinical isolates of Escherichia coli and Klebsiella pneumoniae from Northeast India. Indian J Pathol Microbiol. 2014, 57:249-54. 10.4103\/0377-4929.134698","journal-title":"Indian J Pathol Microbiol"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.4103\/ijmr.IJMR_2085_17","article-title":"Molecular characterization &amp; epidemiology of carbapenem-resistant Acinetobacter baumannii collected across India","volume":"149","author":"Vijayakumar S","year":"2019","unstructured":"Vijayakumar S, Mathur P, Kapil A, et al.. Molecular characterization &amp;amp; epidemiology of carbapenem-resistant Acinetobacter baumannii collected across India. Indian J Med Res. 2019, 149:240-6. 10.4103\/ijmr.IJMR_2085_17","journal-title":"Indian J Med Res"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1054\/drup.2000.0152","article-title":"Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment","volume":"3","author":"Hancock RE","year":"2000","unstructured":"Hancock RE, Speert DP. Antibiotic resistance in Pseudomonas aeruginosa: mechanisms and impact on treatment. Drug Resist Updat. 2000, 3:247-55. 10.1054\/drup.2000.0152","journal-title":"Drug Resist Updat"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkz326","article-title":"Mechanisms and phenotypic consequences of acquisition of tigecycline resistance by Stenotrophomonas maltophilia","volume":"74","author":"Blanco P","year":"2019","unstructured":"Blanco P, Corona F, Martinez JL. Mechanisms and phenotypic consequences of acquisition of tigecycline resistance by Stenotrophomonas maltophilia. J Antimicrob Chemother. 2019, 74:3221-30. 10.1093\/jac\/dkz326","journal-title":"J Antimicrob Chemother"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.44.7.1878-1886.2000","article-title":"Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum","volume":"44","author":"Bellais S","year":"2000","unstructured":"Bellais S, Aubert D, Naas T, Nordmann P. Molecular and biochemical heterogeneity of class B carbapenem-hydrolyzing beta-lactamases in Chryseobacterium meningosepticum. Antimicrob Agents Chemother. 2000, 44:1878-86. 10.1128\/AAC.44.7.1878-1886.2000","journal-title":"Antimicrob Agents Chemother"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1128\/JCM.38.1.460-461.2000","article-title":"Isolation of Pantoea agglomerans in two cases of septic monoarthritis after plant thorn and wood sliver injuries","volume":"38","author":"De Champs C","year":"2000","unstructured":"De Champs C, Le Seaux S, Dubost JJ, Boisgard S, Sauvezie B, Sirot J. Isolation of Pantoea agglomerans in two cases of septic monoarthritis after plant thorn and wood sliver injuries. J Clin Microbiol. 2000, 38:460-1. 10.1128\/JCM.38.1.460-461.2000","journal-title":"J Clin Microbiol"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0224731","article-title":"Molecular validation of clinical Pantoea isolates identified by MALDI-TOF","volume":"14","author":"Soutar CD","year":"2019","unstructured":"Soutar CD, Stavrinides J. Molecular validation of clinical Pantoea isolates identified by MALDI-TOF. PLoS One. 2019, 14:e0224731. 10.1371\/journal.pone.0224731","journal-title":"PLoS One"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.4103\/ijo.IJO_1455_19","article-title":"Kocuria kristinae interface keratitis following deep anterior lamellar keratoplasty","volume":"68","author":"Kate A","year":"2020","unstructured":"Kate A, Joseph J, Bagga B. Kocuria kristinae interface keratitis following deep anterior lamellar keratoplasty. Indian J Ophthalmol. 2020, 68:1463-6. 10.4103\/ijo.IJO_1455_19","journal-title":"Indian J Ophthalmol"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1099\/mgen.0.001055","article-title":"Emergence of linezolid-resistant Enterococcus faecium in a tertiary hospital in Copenhagen","volume":"9","author":"Misiakou MA","year":"2023","unstructured":"Misiakou MA, Hertz FB, Sch\u00f8nning K, H\u00e4ussler S, Nielsen KL. Emergence of linezolid-resistant Enterococcus faecium in a tertiary hospital in Copenhagen. Microb Genom. 2023, 9:10.1099\/mgen.0.001055","journal-title":"Microb Genom"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.4103\/0255-0857.93032","article-title":"Prevalence and antimicrobial resistance pattern of multidrug-resistant enterococci isolated from clinical specimens","volume":"30","author":"Salem-Bekhit MM","year":"2012","unstructured":"Salem-Bekhit MM, Moussa IM, Muharram MM, Alanazy FK, Hefni HM. Prevalence and antimicrobial resistance pattern of multidrug-resistant enterococci isolated from clinical specimens. Indian J Med Microbiol. 2012, 30:44-51. 10.4103\/0255-0857.93032","journal-title":"Indian J Med Microbiol"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/S0196655304005425","article-title":"National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004","volume":"32","year":"2004","unstructured":"National Nosocomial Infections Surveillance (NNIS) System Report, data summary from January 1992 through June 2004, issued October 2004. Am J Infect Control. 2004, 32.470-85. 10.1016\/S0196655304005425","journal-title":"Am J Infect Control"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1111\/myc.13070","article-title":"Fluconazole-resistant Candida parapsilosis strains with a Y132F substitution in the ERG11 gene causing invasive infections in a neonatal unit, South Africa","volume":"63","author":"Magobo RE","year":"2020","unstructured":"Magobo RE, Lockhart SR, Govender NP. Fluconazole-resistant Candida parapsilosis strains with a Y132F substitution in the ERG11 gene causing invasive infections in a neonatal unit, South Africa. Mycoses. 2020, 63:471-7. 10.1111\/myc.13070","journal-title":"Mycoses"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofy358","article-title":"Twenty years of the SENTRY antifungal surveillance program: results for Candida species from 1997-2016","volume":"6","author":"Pfaller MA","year":"2019","unstructured":"Pfaller MA, Diekema DJ, Turnidge JD, Castanheira M, Jones RN. Twenty years of the SENTRY antifungal surveillance program: results for Candida species from 1997-2016. Open Forum Infect Dis. 2019, 6:S79-94. 10.1093\/ofid\/ofy358","journal-title":"Open Forum Infect Dis"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1590\/0074-02760170391","article-title":"The war on cryptococcosis: a review of the antifungal arsenal","volume":"113","author":"Mourad A","year":"2018","unstructured":"Mourad A, Perfect JR. The war on cryptococcosis: a review of the antifungal arsenal. Mem Inst Oswaldo Cruz. 2018, 113:e170391. 10.1590\/0074-02760170391","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1080\/mmy.40.5.479.484","article-title":"Fungemia in a cancer patient caused by fluconazole-resistant Cryptococcus laurentii","volume":"40","author":"Averbuch D","year":"2002","unstructured":"Averbuch D, Boekhoutt T, Falk R, Engelhard D, Shapiro M, Block C, Polacheck I. Fungemia in a cancer patient caused by fluconazole-resistant Cryptococcus laurentii. Med Mycol. 2002, 40:479-84. 10.1080\/mmy.40.5.479.484","journal-title":"Med Mycol"}],"container-title":["Cureus"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.cureus.com\/articles\/371908-tracking-the-invisible-war-automated-profiling-of-multidrug-resistant-pathogens-in-a-tertiary-care-teaching-hospital-in-central-india","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,11]],"date-time":"2025-06-11T15:59:12Z","timestamp":1749657552000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.cureus.com\/articles\/371908-tracking-the-invisible-war-automated-profiling-of-multidrug-resistant-pathogens-in-a-tertiary-care-teaching-hospital-in-central-india"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,11]]},"references-count":22,"URL":"https:\/\/doi.org\/10.7759\/cureus.85778","relation":{},"ISSN":["2168-8184"],"issn-type":[{"value":"2168-8184","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6,11]]}}}